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4 results on '"Leser, Gunilla"'

3. The Curative and Palliative Potential of the Monoclonal Antibody MOv18 Labelled with [sup 211] At in Nude Mice with Intraperitoneally growing Ovarian Cancer Xenografts - A Long-Term Study.

Author

Andersson, Håkan, Lindegren, Sture, Bäck, Tom, Jacobsson, Lars, Leser, Gunilla, and Horvath, György

Subjects
MONOCLONAL antibodies, OVARIAN diseases, THERAPEUTICS
Abstract

Investigates the therapeutic efficacy of [sup 112]astatine-labelled specific monoclonal antibody in nude mice with intraperitoneally growing ovarian cancer xenograft. Injection of antibody peritoneally on microscopic cancer growth; Prolonged survival on treated mice; Treatment delayed production of ascites.

Published
2000

4. Biokinetics of the Monoclonal Antibodies MOv 18, OV 185 and OV 197 Labelled with 125I According to the m-MeATE Method or the Iodogen Method in Nude Mice with Ovarian Cancer Xenografts.

Author

Andersson, Håkan, Lindegren, Sture, Bäck, Tom, Jacobsson, Lars, Leser, Gunilla, and Horvath, György

Subjects
CHEMICAL kinetics, MONOCLONAL antibodies, OVARIAN transplantation
Abstract

Investigates the biodistribution of the radiolabelled monoclonal antibodies MO[sub v]18, OV185 and OV197 in nude mice with ovarian cancer xenograft. Identification of the tumor/blood ratio and the localization index; Rate of tumor uptake in relation to tumor size; Details of the labelling with [sup 125]I according to the iodegen method.

Published
1999

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