1. Evaluation of an Artificial Intelligence System for Retinopathy of Prematurity Screening in Nepal and Mongolia
- Author
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Emily Cole, MD, MPH, Nita G. Valikodath, MD, MS, Tala Al-Khaled, MD, Sanyam Bajimaya, MBBS, MD, Sagun KC, MSc, Tsengelmaa Chuluunbat, MD, Bayalag Munkhuu, MD, Karyn E. Jonas, MSN, RN-BC, Chimgee Chuluunkhuu, MD, Leslie D. MacKeen, BSc, Vivien Yap, MD, Joelle Hallak, PhD, Susan Ostmo, MSc, Wei-Chi Wu, MD, PhD, Aaron S. Coyner, PhD, Praveer Singh, PhD, Jayashree Kalpathy-Cramer, PhD, Michael F. Chiang, MD, J. Peter Campbell, MD, MPH, and R. V. Paul Chan, MD more...
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Artificial intelligence ,Deep learning ,Mongolia ,Nepal ,Retinopathy of prematurity ,Ophthalmology ,RE1-994 - Abstract
Purpose: To evaluate the performance of a deep learning (DL) algorithm for retinopathy of prematurity (ROP) screening in Nepal and Mongolia. Design: Retrospective analysis of prospectively collected clinical data. Participants: Clinical information and fundus images were obtained from infants in 2 ROP screening programs in Nepal and Mongolia. Methods: Fundus images were obtained using the Forus 3nethra neo (Forus Health) in Nepal and the RetCam Portable (Natus Medical, Inc.) in Mongolia. The overall severity of ROP was determined from the medical record using the International Classification of ROP (ICROP). The presence of plus disease was determined independently in each image using a reference standard diagnosis. The Imaging and Informatics for ROP (i-ROP) DL algorithm was trained on images from the RetCam to classify plus disease and to assign a vascular severity score (VSS) from 1 through 9. Main Outcome Measures: Area under the receiver operating characteristic curve and area under the precision-recall curve for the presence of plus disease or type 1 ROP and association between VSS and ICROP disease category. Results: The prevalence of type 1 ROP was found to be higher in Mongolia (14.0%) than in Nepal (2.2%; P more...
- Published
- 2022
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