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1. Treatment patterns for AL amyloidosis after frontline daratumumab, bortezomib, cyclophosphamide, and dexamethasone treatment failures

Author

Zanwar, Saurabh, Gertz, Morie A., Muchtar, Eli, Buadi, Francis K., Kourelis, Taxiarchis, Gonsalves, Wilson, Go, Ronald S., Hayman, Suzanne, Kapoor, Prashant, Binder, Moritz, Cook, Joselle, Dingli, David, Leung, Nelson, Lin, Yi, Warsame, Rahma, Fonder, Amie, Hobbs, Miriam, Hwa, Yi Lisa, Kyle, Robert A., Rajkumar, S. Vincent, Kumar, Shaji, and Dispenzieri, Angela

Published
2024
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2. Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management

Author

Khurana, Arushi, Rosenthal, Allison C., Mohty, Razan, Gaddam, Mamatha, Bansal, Radhika, Hathcock, Matthew A., Nedved, Adrienne N., Durani, Urshila, Iqbal, Madiha, Wang, Yucai, Paludo, Jonas, Villasboas, J. C., Dingli, David, Kourelis, Taxiarchis, Leung, Nelson, Alkhateeb, Hassan, Ruff, Michael W., Gallo de Moraes, Alice, Vergidis, Paschalis, Herrmann, Joerg, Kenderian, Saad S., Bennani, N. Nora, Johnston, Patrick B., Ansell, Stephen M., and Lin, Yi

Published
2024
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3. Diagnostic yield of exome and genome sequencing after non-diagnostic multi-gene panels in patients with single-system diseases

Author

Wilke, Matheus V. M. B., Klee, Eric W., Dhamija, Radhika, Fervenza, Fernando C., Thomas, Brittany, Leung, Nelson, Hogan, Marie C., Hager, Megan M., Kolbert, Kayla J., Kemppainen, Jennifer L., Loftus, Elle C., Leitzen, Katie M., Vitek, Carolyn R., McAllister, Tammy, Lazaridis, Konstantinos N., and Pinto e Vairo, Filippo

Published
2024
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4. Outcomes of patients with multiple myeloma refractory to standard dose vs low dose lenalidomide

Author

Goel, Utkarsh, Charalampous, Charalampos, Kapoor, Prashant, Binder, Moritz, Buadi, Francis K., Dingli, David, Dispenzieri, Angela, Fonder, Amie, Gertz, Morie A., Gonsalves, Wilson I., Hayman, Suzanne R., Hobbs, Miriam A., Hwa, Yi L., Kourelis, Taxiarchis, Lacy, Martha Q., Leung, Nelson, Lin, Yi, Warsame, Rahma M., Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2024
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5. Assessment of Glomerular Filtration Rate in Patients with Cancer: A Statement from the American Society of Onco-Nephrology

Author

Kitchlu, Abhijat, Costa E Silva, Verônica T., Anand, Shuchi, Kala, Jaya, Abudayyeh, Ala, Inker, Lesley A., Rosner, Mitchell H., Karam, Sabine, Gudsoorkar, Prakash, Gupta, Shruti, Chen, Sheldon, Klomjit, Nattawat, Leung, Nelson, Milanez, Tomaz, Motwani, Shveta S., Khalid, Sheikh B., Srinivasan, Vinay, Wanchoo, Rimda, Beumer, Jan H., Liu, Geoffrey, Tannir, Nizar M., Orchanian-Cheff, Ani, Geng, Yimin, and Herrmann, Sandra M.

Published
2024
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6. Assessment of GFR in Patients with Cancer Part 2: Anticancer Therapies – Perspectives from the ASON

Author

Kitchlu, Abhijat, Costa E Silva, Verônica T., Anand, Shuchi, Kala, Jaya, Abudayyeh, Ala, Inker, Lesley A., Rosner, Mitchell H., Karam, Sabine, Gudsoorkar, Prakash, Gupta, Shruti, Chen, Sheldon, Klomjit, Nattawat, Leung, Nelson, Milanez, Tomaz, Motwani, Shveta S., Khalid, Sheikh B., Srinivasan, Vinay, Wanchoo, Rimda, Beumer, Jan H., Liu, Geoffrey, Tannir, Nizar M., Orchanian-Cheff, Ani, Geng, Yimin, and Herrmann, Sandra M.

Published
2024
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7. Correction: Tracking daratumumab clearance using mass spectrometry: implications on M protein monitoring and reusing daratumumab

Author

Abdallah, Nadine, Murray, David, Dispenzieri, Angela, Kapoor, Prashant, Gertz, Morie A., Lacy, Martha Q., Hayman, Suzanne R., Buadi, Francis K., Gonsalves, Wilson, Muchtar, Eli, Leung, Nelson, Dingli, David, Kourelis, Taxiarchis, Warsame, Rahma, Binder, Moritz, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji

Published
2024
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8. Correction: Family history of plasma cell disorders is associated with improved survival in MGUS, multiple myeloma, and systemic AL amyloidosis

Author

Visram, Alissa, Vachon, Celine, Baughn, Linda B., Larson, Dirk, Smadbeck, James, Dispenzieri, Angela, Kapoor, Prashant, Lacy, Martha Q., Gertz, Morie A., Buadi, Francis K., Hayman, Suzanne R., Dingli, David, Kourelis, Taxiarchis, Gonsalves, Wilson, Warsame, Rahma, Muchtar, Eli, Leung, Nelson, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji

Published
2024
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10. Correction: Value of bone marrow examination in determining response to therapy in patients with multiple myeloma in the context of mass spectrometry-based M-protein assessment

Author

Claveau, Jean-Sébastien, Murray, David L., Dispenzieri, Angela, Kapoor, Prashant, Binder, Moritz, Buadi, Francis, Dingli, David, Fonder, Amie, Gertz, Morie, Gonsalves, Wilson, Hayman, Suzanne, Hobbs, Miriam, Hwa, Yi Lisa, Kourelis, Taxiarchis, Lacy, Martha, Leung, Nelson, Lin, Yi, Warsame, Rahma, Kyle, Robert A., Rajkumar, Vincent, and Kumar, Shaji K.

Published
2024
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12. Association of Thrombocytopenia With Disease Burden, High-Risk Cytogenetics, and Survival in Newly Diagnosed Multiple Myeloma Patients Treated With Novel Therapies

Author

Charalampous, Charalampos, Goel, Utkarsh, Kapoor, Prashant, Binder, Moritz, Buadi, Francis, Dingli, David, Dispenzieri, Angela, Fonder, Amie, Gertz, Morie, Gonsalves, Wilson, Hayman, Suzanne, Hobbs, Miriam, Hwa, Yi Lisa, Kourelis, Taxiarchis, Lacy, Martha, Leung, Nelson, Lin, Yi, Warsame, Rahma, Kyle, Robert A., Rajkumar, Vincent, and Kumar, Shaji K

Published
2024
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14. Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia. 2022 Jul;36(7):1720–1748

Author

Alaggio, Rita, Amador, Catalina, Anagnostopoulos, Ioannis, Attygalle, Ayoma D., de Oliveira Araujo, Iguaracyra Barreto, Berti, Emilio, Bhagat, Govind, Borges, Anita Maria, Boyer, Daniel, Calaminici, Mariarita, Chadburn, Amy, Chan, John K. C., Cheuk, Wah, Chng, Wee-Joo, Choi, John K., Chuang, Shih-Sung, Coupland, Sarah E., Czader, Magdalena, Dave, Sandeep S., de Jong, Daphne, Di Napoli, Arianna, Du, Ming-Qing, Elenitoba-Johnson, Kojo S., Ferry, Judith, Geyer, Julia, Gratzinger, Dita, Guitart, Joan, Gujral, Sumeet, Harris, Marian, Harrison, Christine J., Hartmann, Sylvia, Hochhaus, Andreas, Jansen, Patty M., Karube, Kennosuke, Kempf, Werner, Khoury, Joseph, Kimura, Hiroshi, Klapper, Wolfram, Kovach, Alexandra E., Kumar, Shaji, Lazar, Alexander J., Lazzi, Stefano, Leoncini, Lorenzo, Leung, Nelson, Leventaki, Vasiliki, Li, Xiao-Qiu, Lim, Megan S., Liu, Wei-Ping, Louissaint, Jr, Abner, Marcogliese, Andrea, Medeiros, L. Jeffrey, Michal, Michael, Miranda, Roberto N., Mitteldorf, Christina, Montes-Moreno, Santiago, Morice, William, Nardi, Valentina, Naresh, Kikkeri N., Natkunam, Yasodha, Ng, Siok-Bian, Oschlies, Ilske, Ott, German, Parrens, Marie, Pulitzer, Melissa, Rajkumar, S. Vincent, Rawstron, Andrew C., Rech, Karen, Rosenwald, Andreas, Said, Jonathan, Sarkozy, Clémentine, Sayed, Shahin, Saygin, Caner, Schuh, Anna, Sewell, William, Siebert, Reiner, Sohani, Aliyah R., Suzuki, Ritsuro, Tooze, Reuben, Traverse-Glehen, Alexandra, Vega, Francisco, Vergier, Beatrice, Wechalekar, Ashutosh D., Wood, Brent, Xerri, Luc, and Xiao, Wenbin

Published
2023
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15. Multimode photon blockade

Author

Chakram, Srivatsan, He, Kevin, Dixit, Akash V, Oriani, Andrew E, Naik, Ravi K, Leung, Nelson, Kwon, Hyeokshin, Ma, Wen-Long, Jiang, Liang, and Schuster, David I

Subjects
quant-ph, cond-mat.mes-hall, cond-mat.supr-con, Mathematical Sciences, Physical Sciences, Fluids & Plasmas
Abstract

Interactions are essential for the creation of correlated quantum many-body states. Although two-body interactions underlie most natural phenomena, three- and four-body interactions are important for the physics of nuclei1, exotic few-body states in ultracold quantum gases2, the fractional quantum Hall effect3, quantum error correction4 and holography5,6. Recently, a number of artificial quantum systems have emerged as simulators for many-body physics, featuring the ability to engineer strong interactions. However, the interactions in these systems have largely been limited to the two-body paradigm and require building up multibody interactions by combining two-body forces. Here we implement a scheme to create a higher-order interaction between photons stored in multiple electromagnetic modes of a microwave cavity. The system is dressed such that there is collectively no interaction until a target total photon number is reached across multiple distinct modes, at which point the photons interact strongly. In our demonstration, we create interactions involving up to three bodies and across up to five modes. We harness the interaction to prepare single-mode Fock states and multimode W states, which we verify by introducing a multimode Wigner tomography method.

Published
2022

16. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

Author

Alaggio, Rita, Amador, Catalina, Anagnostopoulos, Ioannis, Attygalle, Ayoma D, Araujo, Iguaracyra Barreto de Oliveira, Berti, Emilio, Bhagat, Govind, Borges, Anita Maria, Boyer, Daniel, Calaminici, Mariarita, Chadburn, Amy, Chan, John KC, Cheuk, Wah, Chng, Wee-Joo, Choi, John K, Chuang, Shih-Sung, Coupland, Sarah E, Czader, Magdalena, Dave, Sandeep S, de Jong, Daphne, Du, Ming-Qing, Elenitoba-Johnson, Kojo S, Ferry, Judith, Geyer, Julia, Gratzinger, Dita, Guitart, Joan, Gujral, Sumeet, Harris, Marian, Harrison, Christine J, Hartmann, Sylvia, Hochhaus, Andreas, Jansen, Patty M, Karube, Kennosuke, Kempf, Werner, Khoury, Joseph, Kimura, Hiroshi, Klapper, Wolfram, Kovach, Alexandra E, Kumar, Shaji, Lazar, Alexander J, Lazzi, Stefano, Leoncini, Lorenzo, Leung, Nelson, Leventaki, Vasiliki, Li, Xiao-Qiu, Lim, Megan S, Liu, Wei-Ping, Louissaint, Abner, Marcogliese, Andrea, Medeiros, L Jeffrey, Michal, Michael, Miranda, Roberto N, Mitteldorf, Christina, Montes-Moreno, Santiago, Morice, William, Nardi, Valentina, Naresh, Kikkeri N, Natkunam, Yasodha, Ng, Siok-Bian, Oschlies, Ilske, Ott, German, Parrens, Marie, Pulitzer, Melissa, Rajkumar, S Vincent, Rawstron, Andrew C, Rech, Karen, Rosenwald, Andreas, Said, Jonathan, Sarkozy, Clémentine, Sayed, Shahin, Saygin, Caner, Schuh, Anna, Sewell, William, Siebert, Reiner, Sohani, Aliyah R, Tooze, Reuben, Traverse-Glehen, Alexandra, Vega, Francisco, Vergier, Beatrice, Wechalekar, Ashutosh D, Wood, Brent, Xerri, Luc, and Xiao, Wenbin

Subjects
Cancer, Hematologic Neoplasms, Humans, Lymphoma, World Health Organization, Clinical Sciences, Oncology and Carcinogenesis, Immunology
Abstract

We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.

Published
2022

19. Comparison of daratumumab-based regimens as second-line therapy in relapsed/refractory multiple myeloma

Author

Charalampous, Charalampos, Goel, Utkarsh, Kapoor, Prashant, Binder, Moritz, Buadi, Francis K., Cook, Joselle, Dingli, David, Dispenzieri, Angela, Fonder, Amie L., Gertz, Morie A., Gonsalves, Wilson, Hayman, Suzanne R., Hobbs, Miriam A., Hwa, Yi L., Kourelis, Taxiarchis, Lacy, Martha Q., Leung, Nelson, Lin, Yi, Warsame, Rahma, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2023
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20. Long-term outcomes of allogeneic stem cell transplant in multiple myeloma

Author

Schmidt, Walker M., Perera, Nirosha D., Buadi, Francis K., Hayman, Suzanne R., Kumar, Shaji K., Dispenzieri, Angela, Dingli, David, Cook, Joselle, Lacy, Martha Q., Kapoor, Prashant, Leung, Nelson, Muchtar, Eli, Warsame, Rahma M., Kourelis, Taxiarchis, Binder, Moritz, Gonsalves, Wilson I., Hogan, William J., and Gertz, Morie A.

Published
2023
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22. Defining drug/drug class refractoriness vs lines of therapy in relapsed/refractory multiple myeloma

Author

Goel, Utkarsh, Charalampous, Charalampos, Kapoor, Prashant, Binder, Moritz, Buadi, Francis K., Dingli, David, Dispenzieri, Angela, Fonder, Amie, Gertz, Morie A., Gonsalves, Wilson I., Hayman, Suzanne R., Hobbs, Miriam A., Hwa, Yi L., Kourelis, Taxiarchis, Lacy, Martha Q., Leung, Nelson, Lin, Yi, Warsame, Rahma M., Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2023
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24. Autosomal dominant ApoA4 mutations present as tubulointerstitial kidney disease with medullary amyloidosis

Author

Kmochová, Tereza, Kidd, Kendrah O., Orr, Andrew, Hnízda, Aleš, Hartmannová, Hana, Hodaňová, Kateřina, Vyleťal, Petr, Naušová, Karolína, Brinsa, Vítězslav, Trešlová, Helena, Sovová, Jana, Barešová, Veronika, Svojšová, Klára, Vrbacká, Alena, Stránecký, Viktor, Robins, Victoria C., Taylor, Abbigail, Martin, Lauren, Rivas-Chavez, Ana, Payne, Riley, Bleyer, Heidi A., Williams, Adrienne, Rennke, Helmut G., Weins, Astrid, Short, Patrick J., Agrawal, Varun, Storsley, Leroy J., Waikar, Sushrut S., McPhail, Ellen D., Dasari, Surendra, Leung, Nelson, Hewlett, Tom, Yorke, Jake, Gaston, Daniel, Geldenhuys, Laurette, Samuels, Mark, Levine, Adam P., West, Michael, Hůlková, Helena, Pompach, Petr, Novák, Petr, Weinberg, Richard B., Bedard, Karen, Živná, Martina, Sikora, Jakub, Bleyer, Anthony J., Sr., and Kmoch, Stanislav

Published
2024
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29. Multimode photon blockade

Author

Chakram, Srivatsan, He, Kevin, Dixit, Akash V., Oriani, Andrew E., Naik, Ravi K., Leung, Nelson, Kwon, Hyeokshin, Ma, Wen-Long, Jiang, Liang, and Schuster, David I.

Subjects
Quantum Physics, Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Superconductivity
Abstract

Interactions are essential for the creation of correlated quantum many-body states. While two-body interactions underlie most natural phenomena, three- and four-body interactions are important for the physics of nuclei [1], exotic few-body states in ultracold quantum gases [2], the fractional quantum Hall effect [3], quantum error correction [4], and holography [5, 6]. Recently, a number of artificial quantum systems have emerged as simulators for many-body physics, featuring the ability to engineer strong interactions. However, the interactions in these systems have largely been limited to the two-body paradigm, and require building up multi-body interactions by combining two-body forces. Here, we demonstrate a pure N-body interaction between microwave photons stored in an arbitrary number of electromagnetic modes of a multimode cavity. The system is dressed such that there is collectively no interaction until a target total photon number is reached across multiple distinct modes, at which point they interact strongly. The microwave cavity features 9 modes with photon lifetimes of $\sim 2$ ms coupled to a superconducting transmon circuit, forming a multimode circuit QED system with single photon cooperativities of $\sim10^9$. We generate multimode interactions by using cavity photon number resolved drives on the transmon circuit to blockade any multiphoton state with a chosen total photon number distributed across the target modes. We harness the interaction for state preparation, preparing Fock states of increasing photon number via quantum optimal control pulses acting only on the cavity modes. We demonstrate multimode interactions by generating entanglement purely with uniform cavity drives and multimode photon blockade, and characterize the resulting two- and three-mode W states using a new protocol for multimode Wigner tomography., Comment: 5 pages of main text with 5 figures. 11 pages of supplementary information with 10 figures

Published
2020
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30. Impact of cytogenetic abnormalities on the risk of disease progression in solitary bone plasmacytomas

Author

Yadav, Udit, Kumar, Shaji K., Baughn, Linda B., Dispenzieri, Angela, Greipp, Patricia, Ketterling, Rhett, Jevremovic, Dragan, Buadi, Francis K., Dingli, David, Lacy, Martha Q., Fonseca, Rafael, Bergsagel, P. Leif, Ailawadhi, Sikander, Roy, Vivek, Parrondo, Ricardo, Sher, Taimur, Hayman, Suzanne R., Kapoor, Prashant, Leung, Nelson, Cook, Joselle, Binder, Moritz, Muchtar, Eli, Warsame, Rahma, Kourelis, Taxiarchis V., Go, Ronald S., Lin, Yi, Seth, Abhishek, Lester, Scott C., Breen, William G., Kyle, Robert A., Gertz, Morie A., Rajkumar, S. Vincent, and Gonsalves, Wilson I.

Published
2023
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32. Value of bone marrow examination in determining response to therapy in patients with multiple myeloma in the context of mass spectrometry-based M-protein assessment

Author

Claveau, Jean-Sébastien, Murray, David L., Dispenzieri, Angela, Kapoor, Prashant, Binder, Moritz, Buadi, Francis, Dingli, David, Fonder, Amie, Gertz, Morie, Gonsalves, Wilson, Hayman, Suzanne, Hobbs, Miriam, Hwa, Yi Lisa, Kourelis, Taxiarchis, Lacy, Martha, Leung, Nelson, Lin, Yi, Warsame, Rahma, Kyle, Robert A., Rajkumar, Vincent, and Kumar, Shaji K.

Published
2023
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33. Outcomes of patients with primary refractory multiple myeloma in the era of triplet and quadruplet induction therapy

Author

Charalampous, Charalampos, Goel, Utkarsh, Kapoor, Prashant, Binder, Moritz, Buadi, Francis K., Cook, Joselle, Dingli, David, Dispenzieri, Angela, Fonder, Amie L., Gertz, Morie A., Gonsalves, Wilson, Hayman, Suzanne R., Hobbs, Miriam A., Hwa, Yi L., Kourelis, Taxiarchis, Lacy, Martha Q., Leung, Nelson, Lin, Yi, Warsame, Rahma, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2023
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34. Partial Compilation of Variational Algorithms for Noisy Intermediate-Scale Quantum Machines

Author

Gokhale, Pranav, Ding, Yongshan, Propson, Thomas, Winkler, Christopher, Leung, Nelson, Shi, Yunong, Schuster, David I., Hoffmann, Henry, and Chong, Frederic T.

Subjects
Quantum Physics, Electrical Engineering and Systems Science - Systems and Control
Abstract

Quantum computing is on the cusp of reality with Noisy Intermediate-Scale Quantum (NISQ) machines currently under development and testing. Some of the most promising algorithms for these machines are variational algorithms that employ classical optimization coupled with quantum hardware to evaluate the quality of each candidate solution. Recent work used GRadient Descent Pulse Engineering (GRAPE) to translate quantum programs into highly optimized machine control pulses, resulting in a significant reduction in the execution time of programs. This is critical, as quantum machines can barely support the execution of short programs before failing. However, GRAPE suffers from high compilation latency, which is untenable in variational algorithms since compilation is interleaved with computation. We propose two strategies for partial compilation, exploiting the structure of variational circuits to pre-compile optimal pulses for specific blocks of gates. Our results indicate significant pulse speedups ranging from 1.5x-3x in typical benchmarks, with only a small fraction of the compilation latency of GRAPE., Comment: Appearing in the 52nd Annual IEEE/ACM International Symposium on Microarchitecture (MICRO-52), October 12-16, 2019, Columbus, OH, USA

Published
2019
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35. Management of multiple myeloma-related renal impairment: recommendations from the International Myeloma Working Group

Author

Dimopoulos, Meletios A, Merlini, Giampaolo, Bridoux, Frank, Leung, Nelson, Mikhael, Joseph, Harrison, Simon J, Kastritis, Efstathios, Garderet, Laurent, Gozzetti, Alessandro, van de Donk, Niels W C J, Weisel, Katja C, Badros, Ashraf Z, Beksac, Meral, Hillengass, Jens, Mohty, Mohamad, Ho, P Joy, Ntanasis-Stathopoulos, Ioannis, Mateos, Maria-Victoria, Richardson, Paul, Blade, Joan, Moreau, Philippe, San-Miguel, Jesus, Munshi, Nikhil, Rajkumar, S Vincent, Durie, Brian G M, Ludwig, Heinz, and Terpos, Evangelos

Published
2023
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36. Optimized Compilation of Aggregated Instructions for Realistic Quantum Computers

Author

Shi, Yunong, Leung, Nelson, Gokhale, Pranav, Rossi, Zane, Schuster, David I., Hoffman, Henry, and Chong, Fred T.

Subjects
Quantum Physics, Computer Science - Computation and Language
Abstract

Recent developments in engineering and algorithms have made real-world applications in quantum computing possible in the near future. Existing quantum programming languages and compilers use a quantum assembly language composed of 1- and 2-qubit (quantum bit) gates. Quantum compiler frameworks translate this quantum assembly to electric signals (called control pulses) that implement the specified computation on specific physical devices. However, there is a mismatch between the operations defined by the 1- and 2-qubit logical ISA and their underlying physical implementation, so the current practice of directly translating logical instructions into control pulses results in inefficient, high-latency programs. To address this inefficiency, we propose a universal quantum compilation methodology that aggregates multiple logical operations into larger units that manipulate up to 10 qubits at a time. Our methodology then optimizes these aggregates by (1) finding commutative intermediate operations that result in more efficient schedules and (2) creating custom control pulses optimized for the aggregate (instead of individual 1- and 2-qubit operations). Compared to the standard gate-based compilation, the proposed approach realizes a deeper vertical integration of high-level quantum software and low-level, physical quantum hardware. We evaluate our approach on important near-term quantum applications on simulations of superconducting quantum architectures. Our proposed approach provides a mean speedup of $5\times$, with a maximum of $10\times$. Because latency directly affects the feasibility of quantum computation, our results not only improve performance but also have the potential to enable quantum computation sooner than otherwise possible., Comment: 13 pages, to apper in ASPLOS

Published
2019
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37. Outcomes after biochemical or clinical progression in patients with multiple myeloma

Author

Goldman-Mazur, Sarah, Visram, Alissa, Kapoor, Prashant, Dispenzieri, Angela, Lacy, Martha Q., Gertz, Morie A., Buadi, Francis K., Hayman, Suzanne R., Dingli, David, Kourelis, Taxiarchis, Gonsalves, Wilson, Warsame, Rahma, Muchtar, Eli, Leung, Nelson, Binder, Moritz, Fonder, Amie, Hobbs, Miriam, Hwa, Yi Lisa, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2023
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39. Pathological characteristics of light chain crystalline podocytopathy

Author

Nasr, Samih H., Kudose, Satoru, Javaugue, Vincent, Harel, Stéphanie, Said, Samar M., Pascal, Virginie, Stokes, M. Barry, Vrana, Julie A., Dasari, Surendra, Theis, Jason D., Osuchukwu, George A., Sathick, Insara Jaffer, Das, Arjun, Kashkouli, Ali, Suchin, Elliot J., Liss, Yaakov, Suldan, Zalman, Verine, Jerome, Arnulf, Bertrand, Talbot, Alexis, Sethi, Sanjeev, Zaidan, Mohamad, Goujon, Jean-Michel, Valeri, Anthony M., Mcphail, Ellen D., Sirac, Christophe, Leung, Nelson, Bridoux, Frank, and D’Agati, Vivette D.

Published
2023
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41. Complement gene variant effect on relapse of complement-mediated thrombotic microangiopathy after eculizumab cessation

Author

Amer, Hatem, Fervenza, Fernando, Leung, Nelson, Tran, Cheryl, Zand, Ladan, Alkhateeb, Hassan, Go, Ronald, Hogan, William, Hook, Christopher, Pruthi, Rajiv, Sridharan, Meera, Adamski, Jill, Murray, David, Winters, Jeffrey, Alexander, Mariam, Chen, Dong, Moyer, Ann, Sethi, Sanjeev, Willrich, Maria, Heikal, Nahla, Acosta-Medina, Aldo A., Moyer, Ann M., Go, Ronald S., Willrich, Maria Alice V., Fervenza, Fernando C., Bourlon, Christianne, Winters, Jeffrey L., Spears, Grant M., and Bryant, Sandra C.

Published
2023
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42. First relapse in patients with multiple myeloma: Outcomes and predictors.

Author

Seth, Sukriti, primary, Kapoor, Prashant, additional, Buadi, Francis, additional, Binder, Moritz, additional, Cook, Joselle, additional, Dispenzieri, Angela, additional, Dingli, David, additional, Fonder, Amie L., additional, Gertz, Morie A., additional, Gonsalves, Wilson I., additional, Hayman, Suzanne R., additional, Hwa, Lisa, additional, Hobbs, Miriam A., additional, Kourelis, Taxiarchis, additional, Leung, Nelson, additional, Lin, Yi, additional, Muchtar, Eli, additional, Warsame, Rahma M., additional, Rajkumar, S. Vincent, additional, and Kumar, Shaji, additional

Published
2024
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43. A Dissipatively Stabilized Mott Insulator of Photons

Author

Ma, Ruichao, Saxberg, Brendan, Owens, Clai, Leung, Nelson, Lu, Yao, Simon, Jonathan, and Schuster, David I.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

Superconducting circuits are a competitive platform for quantum computation because they offer controllability, long coherence times and strong interactions - properties that are essential for the study of quantum materials comprising microwave photons. However, intrinsic photon losses in these circuits hinder the realization of quantum many-body phases. Here we use superconducting circuits to explore strongly correlated quantum matter by building a Bose-Hubbard lattice for photons in the strongly interacting regime. We develop a versatile method for dissipative preparation of incompressible many-body phases through reservoir engineering and apply it to our system to stabilize a Mott insulator of photons against losses. Site- and time-resolved readout of the lattice allows us to investigate the microscopic details of the thermalization process through the dynamics of defect propagation and removal in the Mott phase. Our experiments demonstrate the power of superconducting circuits for studying strongly correlated matter in both coherent and engineered dissipative settings. In conjunction with recently demonstrated superconducting microwave Chern insulators, we expect that our approach will enable the exploration of topologically ordered phases of matter., Comment: Maintext 10 pages, 5 figures; Supplementary Information with 12 figures and 3 tables. Very similar to the published version

Published
2018
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45. Phase 2 trial of ixazomib, cyclophosphamide, and dexamethasone for previously untreated light chain amyloidosis

Author

Muchtar, Eli, Gertz, Morie A., LaPlant, Betsy R., Buadi, Francis K., Leung, Nelson, O'Brien, Patrick, Bergsagel, P. Leif, Fonder, Amie, Hwa, Yi Lisa, Hobbs, Miriam, Helgeson, Dania K., Bradt, Erin E., Gonsalves, Wilson, Lacy, Martha Q., Kapoor, Prashant, Siddiqui, Mustaqueem, Larsen, Jeremy T., Warsame, Rahma, Hayman, Suzanne R., Go, Ronald S., Dingli, David, Kourelis, Taxiarchis V., Dispenzieri, Angela, Rajkumar, S. Vincent, and Kumar, Shaji K.

Published
2022
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49. Clinical activity of single-dose systemic oncolytic VSV virotherapy in patients with relapsed refractory T-cell lymphoma

Author

Cook, Joselle, Peng, Kah-Whye, Witzig, Thomas E., Broski, Stephen M., Villasboas, Jose C., Paludo, Jonas, Patnaik, Mrinal, Rajkumar, Vincent, Dispenzieri, Angela, Leung, Nelson, Buadi, Francis, Bennani, Nora, Ansell, Stephen M., Zhang, Lianwen, Packiriswamy, Nandakumar, Balakrishnan, Baskar, Brunton, Bethany, Giers, Marissa, Ginos, Brenda, Dueck, Amylou C., Geyer, Susan, Gertz, Morie A., Warsame, Rahma, Go, Ronald S., Hayman, Suzanne R., Dingli, David, Kumar, Shaji, Bergsagel, Leif, Munoz, Javier L., Gonsalves, Wilson, Kourelis, Taxiarchis, Muchtar, Eli, Kapoor, Prashant, Kyle, Robert A., Lin, Yi, Siddiqui, Mustaqeem, Fonder, Amie, Hobbs, Miriam, Hwa, Lisa, Naik, Shruthi, Russell, Stephen J., and Lacy, Martha Q.

Published
2022
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50. Family history of plasma cell disorders is associated with improved survival in MGUS, multiple myeloma, and systemic AL amyloidosis

Author

Visram, Alissa, Vachon, Celine, Baughn, Linda B., Larson, Dirk, Smadbeck, James, Dispenzieri, Angela, Kapoor, Prashant, Lacy, Martha Q., Gertz, Morie A., Buadi, Francis K., Hayman, Suzanne R., Dingli, David, Kourelis, Taxiarchis, Gonsalves, Wilson, Warsame, Rahma, Muchtar, Eli, Leung, Nelson, Kyle, Robert A., Rajkumar, S. Vincent, and Kumar, Shaji

Published
2022
Full Text
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