620 results on '"Levings, Megan K."'
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2. Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice
3. SARS-CoV-2 Variants Omicron BA.4/5 and XBB.1.5 Significantly Escape T Cell Recognition in Solid-organ Transplant Recipients Vaccinated Against the Ancestral Strain
4. Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation
5. Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-Versus-Host Disease
6. Adaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults ≥ 50 years: a prospective, observational cohort study
7. Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation
8. PHLPP Signaling in Immune Cells
9. CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation
10. Interactions between islets and regulatory immune cells in health and type 1 diabetes
11. Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection.
12. Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers
13. 1165. Longitudinal Evaluation of SARS-CoV-2 Antibody Response Using Dried Blood Spot Samples Following Vaccination with Three and Four Doses of mRNA-1273, BNT162b2 and/or ChAdOx1-S in Adults Aged 50 and Above: Interim Analysis from the PREVENT-COVID Study
14. 216.6: Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation
15. 213.2: Preliminary Results of the First Clinical Trial to Prevent Graft Rejection in Heart Transplant Children Employing a Cellular Therapy With Autologous Treg Obtained From Thymic Tissue (thyTreg)
16. Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients
17. Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel Disease
18. First-in-human therapy with Treg produced from thymic tissue (thyTreg) in a heart transplant infant
19. Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection
20. Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection
21. A germline heterozygous dominant negativeIKZF2variant causing syndromic primary immune regulatory disorder and ICHAD
22. 3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
23. Adaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults > 50 years: a prospective, observational cohort study
24. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice
25. Alleviating graft-versus-host disease by directing regulatory T cells to the gut … It is all about location, location, location
26. mRNA vaccines take on immune tolerance
27. Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol
28. Transduction of Human T Cell Subsets with Lentivirus
29. Eras of designer Tregs: Harnessing synthetic biology for immune suppression.
30. CAR Tregs protect alloimmune islets against autoimmune destruction
31. CD4+ T Regulatory Cells and Modulation of Undesired Immune Responses
32. Engineering therapeutic T cells to suppress alloimmune responses using TCRs, CARs, or BARs
33. Cancer immunotherapies repurposed for use in autoimmunity
34. Antigen-specific regulatory T cells: are police CARs the answer?
35. Sex biased human thymic architecture guides T cell development through spatially defined niches
36. Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion
37. Targeting regulatory T cell metabolism in disease: novel therapeutic opportunities
38. Strategies for optimizing CITE-seq for human islets and other tissues
39. T cell activation induced marker assays in health and disease
40. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes
41. Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease
42. “FIRST-IN-HUMAN” CLINICAL TRIAL EMPLOYING ADOPTIVE TRANSFER OF AUTOLOGOUS THYMUS-DERIVED TREG CELLS (THYTREG) TO PREVENT GRAFT REJECTION IN HEART-TRANSPLANTED CHILDREN
43. Flagellin-specific human CAR Tregs for immune regulation in IBD
44. Manufacturing next-generation regulatory T-cell therapies
45. Integration of exogenous and endogenous co-stimulatory signals by CAR-Tregs
46. Consequences of adjusting cell density and feed frequency on serum-free expansion of thymic regulatory T cells
47. Fecal microbiota transplant treatment for recurrent Clostridioides difficile infection enhances adaptive immunity to TcdB
48. Taking regulatory T-cell therapy one step further
49. Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis
50. CD56brightCD16– natural killer cells as an important regulatory mechanism in chronic graft-versus-host disease
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