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1. A system to monitor segmental intracellular, interstitial, and intravascular volume and circulatory changes during acute hemodialysis

Author

Montgomery Leslie D., Montgomery Richard W., Gerth Wayne A., Loughry Marty, Lew Susie Q., and Velasquez Manuel T.

Subjects
bioimpedance, plethysmograph, spectroscopy, compartment volumes, blood flow, Medicine (General), R5-920
Abstract

This paper describes a new combined impedance plethysmographic (IPG) and electrical bioimpedance spectroscopic (BIS) instrument and software that allows noninvasive real-time measurement of segmental blood flow and changes in intracellular, interstitial, and intravascular volumes during various fluid management procedures. The impedance device can be operated either as a fixed frequency IPG for the quantification of segmental blood flow and hemodynamics or as a multi-frequency BIS for the recording of intracellular and extracellular resistances at 40 discrete input frequencies. The extracellular volume is then deconvoluted to obtain its intra-vascular and interstitial component volumes as functions of elapsed time. The purpose of this paper is to describe this instrumentation and to demonstrate the information that can be obtained by using it to monitor segmental compartment volumes and circulatory responses of end stage renal disease patients during acute hemodialysis. Such information may prove valuable in the diagnosis and management of rapid changes in the body fluid balance and various clinical treatments.

Published
2017
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2. Hypernatremia in Hyperglycemia: Clinical Features and Relationship to Fractional Changes in Body Water and Monovalent Cations during Its Development

Author

Wagner, Brent, Ing, Todd S, Roumelioti, Maria-Eleni, Sam, Ramin, Argyropoulos, Christos P, Lew, Susie Q, Unruh, Mark L, Dorin, Richard I, Degnan, James H, and Tzamaloukas, Antonios H

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, hyperglycemia, hypernatremia, osmotic diuresis, sodium in fluids lost, potassium in fluids lost, Clinical Sciences, Biomedical and clinical sciences
Abstract

In hyperglycemia, the serum sodium concentration ([Na]S) receives influences from (a) the fluid exit from the intracellular compartment and thirst, which cause [Na]S decreases; (b) osmotic diuresis with sums of the urinary sodium plus potassium concentration lower than the baseline euglycemic [Na]S, which results in a [Na]S increase; and (c), in some cases, gains or losses of fluid, sodium, and potassium through the gastrointestinal tract, the respiratory tract, and the skin. Hyperglycemic patients with hypernatremia have large deficits of body water and usually hypovolemia and develop severe clinical manifestations and significant mortality. To assist with the correction of both the severe dehydration and the hypovolemia, we developed formulas computing the fractional losses of the body water and monovalent cations in hyperglycemia. The formulas estimate varying losses between patients with the same serum glucose concentration ([Glu]S) and [Na]S but with different sums of monovalent cation concentrations in the lost fluids. Among subjects with the same [Glu]S and [Na]S, those with higher monovalent cation concentrations in the fluids lost have higher fractional losses of body water. The sum of the monovalent cation concentrations in the lost fluids should be considered when computing the volume and composition of the fluid replacement for hyperglycemic syndromes.

Published
2024

3. Pseudohyponatremia: Mechanism, Diagnosis, Clinical Associations and Management.

Author

Aziz, Fahad, Sam, Ramin, Lew, Susie Q, Massie, Larry, Misra, Madhukar, Roumelioti, Maria-Eleni, Argyropoulos, Christos P, Ing, Todd S, and Tzamaloukas, Antonios H

Subjects
dilution effect, electrolyte exclusion effect, hyperviscosity, hyponatremia, pseudohypernatremia, pseudohyponatremia, pseudonormonatremia, serum lipids, serum proteins, serum sodium concentration, serum solids content, serum water sodium concentration, Clinical Sciences
Abstract

Pseudohyponatremia remains a problem for clinical laboratories. In this study, we analyzed the mechanisms, diagnosis, clinical consequences, and conditions associated with pseudohyponatremia, and future developments for its elimination. The two methods involved assess the serum sodium concentration ([Na]S) using sodium ion-specific electrodes: (a) a direct ion-specific electrode (ISE), and (b) an indirect ISE. A direct ISE does not require dilution of a sample prior to its measurement, whereas an indirect ISE needs pre-measurement sample dilution. [Na]S measurements using an indirect ISE are influenced by abnormal concentrations of serum proteins or lipids. Pseudohyponatremia occurs when the [Na]S is measured with an indirect ISE and the serum solid content concentrations are elevated, resulting in reciprocal depressions in serum water and [Na]S values. Pseudonormonatremia or pseudohypernatremia are encountered in hypoproteinemic patients who have a decreased plasma solids content. Three mechanisms are responsible for pseudohyponatremia: (a) a reduction in the [Na]S due to lower serum water and sodium concentrations, the electrolyte exclusion effect; (b) an increase in the measured sample's water concentration post-dilution to a greater extent when compared to normal serum, lowering the [Na] in this sample; (c) when serum hyperviscosity reduces serum delivery to the device that apportions serum and diluent. Patients with pseudohyponatremia and a normal [Na]S do not develop water movement across cell membranes and clinical manifestations of hypotonic hyponatremia. Pseudohyponatremia does not require treatment to address the [Na]S, making any inadvertent correction treatment potentially detrimental.

Published
2023

5. The role of intra- and interdialytic sodium balance and restriction in dialysis therapies

Author

Lew, Susie Q, Asci, Gulay, Rootjes, Paul A, Ok, Ercan, Penne, Erik L, Sam, Ramin, Tzamaloukas, Antonios H, Ing, Todd S, and Raimann, Jochen G

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Nutrition, Kidney Disease, Renal and urogenital, sodium, chronic kidney disease, salt, dialysis, hypertension, extracellular volume, diet, Biomedical and clinical sciences, Health sciences
Abstract

The relationship between sodium, blood pressure and extracellular volume could not be more pronounced or complex than in a dialysis patient. We review the patients' sources of sodium exposure in the form of dietary salt intake, medication administration, and the dialysis treatment itself. In addition, the roles dialysis modalities, hemodialysis types, and dialysis fluid sodium concentration have on blood pressure, intradialytic symptoms, and interdialytic weight gain affect patient outcomes are discussed. We review whether sodium restriction (reduced salt intake), alteration in dialysis fluid sodium concentration and the different dialysis types have any impact on blood pressure, intradialytic symptoms, and interdialytic weight gain.

Published
2023

7. Using herbs medically without knowing their composition: are we playing Russian roulette?

Author

Kohn, Orly F, Lew, Susie Q, Wong, Steve Siu-Man, Sam, Ramin, Chen, Hung-Chun, Raimann, Jochen G, Leehey, David J, Tzamaloukas, Antonios H, and Ing, Todd S

Subjects
Medical Biotechnology, Biomedical and Clinical Sciences, Engineering, Biomedical Engineering, Complementary and Integrative Health, Nutrition, Complementary Therapies, Drugs, Chinese Herbal, Humans, Liver, Phytotherapy, Russia, Complementary and alternative medicine, kidney, liver, blood, herbal medicine, traditional medicine, adverse reactions, Medical and Health Sciences, Economics, General & Internal Medicine, Medical biotechnology, Biomedical engineering
Abstract

Herbal medicine, a form of complementary and alternative medicine (CAM), is used throughout the world, in both developing and developed countries. The ingredients in herbal medicines are not standardized by any regulatory agency. Variability exists in the ingredients as well as in their concentrations. Plant products may become contaminated with bacteria and fungi during storage. Therefore, harm can occur to the kidney, liver, and blood components after ingestion. We encourage scientific studies to identify the active ingredients in herbs and to standardize their concentrations in all herbal preparations. Rigorous studies need to be performed in order to understand the effect of herbal ingredients on different organ systems as well as these substances' interaction with other medications.

Published
2022

8. Tunneled Dialysis Catheters: Perspective from a Single Interventional Radiology Center

Author

McCormick, Ellen, Sarin, Shawn, and Lew, Susie Q.

Subjects
Chronic kidney failure -- Care and treatment -- Patient outcomes, Radiology, Interventional -- Methods, Acute renal failure -- Care and treatment -- Patient outcomes, Hemodialysis -- Methods, Catheters -- Usage, Health
Abstract

Tunneled dialysis catheters (TDCs) serve as vascular access for hemodialysis (HD) or plasmapheresis. This study examines the frequency and indications for TDC placement and removal by an interventional radiology service over a 5-year period. Indications for catheter placement (n = 289) included HD for patients with end stage kidney disease (65%) or acute kidney injury (AKI, 24%), and plasmapheresis (11%). Indications for catheter removal included infection (20%), dysfunction (33%), no longer needed (40%), and patient issues (7%). TDCs provide access for HD when a functioning arteriovenous access does not exist. Using a TDC in patients with AKI reduces catheter complications, such as mechanical dysfunction and infection, and provides better dialysis delivery. TDC placement in patients with AKI, despite its time and resource intensity, provides medical and financial benefits. Keywords: End stage kidney disease, interventional radiology, tunneled dialysis catheter, non-tunneled dialysis catheter, acute kidney injury., NCPD 1.2 contact hours Summary * Tunneled dialysis catheters play a key role in providing vascular access for hemodialysis and plasmapheresis. * Tunneled dialysis catheters serve as the vascular access [...]

Published
2023
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10. Edelman Revisited: Concepts, Achievements, and Challenges

Author

Rohrscheib, Mark, Sam, Ramin, Raj, Dominic S, Argyropoulos, Christos P, Unruh, Mark L, Lew, Susie Q, Ing, Todd S, Levin, Nathan W, and Tzamaloukas, Antonios H

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Generic health relevance, dysnatremia, hyponatremia, hypernatremia, osmotic sodium inactivation, hydrophilic compounds, Biomedical and clinical sciences, Health sciences
Abstract

The key message from the 1958 Edelman study states that combinations of external gains or losses of sodium, potassium and water leading to an increase of the fraction (total body sodium plus total body potassium) over total body water will raise the serum sodium concentration ([Na]S), while external gains or losses leading to a decrease in this fraction will lower [Na]S. A variety of studies have supported this concept and current quantitative methods for correcting dysnatremias, including formulas calculating the volume of saline needed for a change in [Na]S are based on it. Not accounting for external losses of sodium, potassium and water during treatment and faulty values for body water inserted in the formulas predicting the change in [Na]S affect the accuracy of these formulas. Newly described factors potentially affecting the change in [Na]S during treatment of dysnatremias include the following: (a) exchanges during development or correction of dysnatremias between osmotically inactive sodium stored in tissues and osmotically active sodium in solution in body fluids; (b) chemical binding of part of body water to macromolecules which would decrease the amount of body water available for osmotic exchanges; and (c) genetic influences on the determination of sodium concentration in body fluids. The effects of these newer developments on the methods of treatment of dysnatremias are not well-established and will need extensive studying. Currently, monitoring of serum sodium concentration remains a critical step during treatment of dysnatremias.

Published
2022

11. A four‐stream method for providing variable dialysis fluid bicarbonate concentrations for bicarbonate‐based dialysis fluid delivery systems

Author

Lew, Susie Q, Sam, Ramin, Tzamaloukas, Antonios H, and Ing, Todd S

Subjects
Engineering, Biomedical Engineering, Bioengineering, Kidney Disease, Dialysis Solutions, Humans, Renal Dialysis, Sodium Bicarbonate, Sodium Chloride, acid concentrate, base concentrate, bicarbonate, dialysate, dialysis fluid, end stage kidney disease, fluid delivery system, four-stream dialysis, hemodialysis, Clinical Sciences, Biomedical engineering
Abstract

BackgroundHemodialysis corrects metabolic acidosis by transferring bicarbonate or bicarbonate equivalents across the dialysis membrane from the dialysis fluid to the plasma. With the conventional three-stream bicarbonate-based dialysis fluid delivery system, a change in the bicarbonate concentration results in changes in the other electrolytes. In practice, the dialysis machine draws either a little less or more from the bicarbonate concentrate and a little more or less from the acid concentrate, respectively in a three-stream delivery system. The result not only changes the bicarbonate concentration of the final dialysis fluid but also causes a minor change in the other ingredients.MethodsWe propose a four-stream bicarbonate-based dialysis fluid delivery system consisting of an acid concentrate, a base concentrate, a product water, and a new sodium chloride concentrate.ResultsBy adjusting the flow rate ratio between the sodium chloride and sodium bicarbonate concentrates, one can achieve the desired bicarbonate concentration in the dialysis fluid without changing the concentration of sodium or ingredients in the acid concentrate. The chloride concentration mirrors the change in bicarbonate but in the opposite direction.ConclusionA four-stream, bicarbonate-based dialysis fluid delivery system allows the bicarbonate concentration to be changed without changing the other constituents of the final dialysis fluid.

Published
2021

14. ACR Appropriateness Criteria® Dialysis Fistula Malfunction

Author

Higgins, Mikhail C.S.S., Diamond, Matthew, Mauro, David M., Kapoor, Baljendra S., Steigner, Michael L., Fidelman, Nicholas, Aghayev, Ayaz, Chamarthy, Murthy R.K., Dedier, Julien, Dillavou, Ellen D., Felder, Mila, Lew, Susie Q., Lockhart, Mark E., Siracuse, Jeffrey J., Dill, Karin E., and Hohenwalter, Eric J.

Published
2023
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17. Medical Subspecialty Telehealth Consults

Author

Lew, Susie Q., additional, Sharma, Shailendra, additional, Siegel, Marc O., additional, Akselrod, Hana, additional, Kaur, Simranjit, additional, Kumar, Anita, additional, Borum, Marie L., additional, and Gross, Hartmut, additional

Published
2021
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18. ACR Appropriateness Criteria® Hydronephrosis on Prior Imaging-Unknown Cause.

Author

Whitworth III, Pat, Courtney, Kelsey G., Oto, Aytekin, Allen, Brian C., Akin, Oguz, Barker, Samantha J., Bartel, Twyla B., DuBeau, Catherine, Gerena, Marielia, Kraft, Kate H., Lew, Susie Q., Mankowski Gettle, Lori, Turkbey, Baris, Uyeda, Jennifer W., and Nikolaidis, Paul

Abstract

Initial imaging evaluation of hydronephrosis of unknown etiology is a complex subject and is dependent on clinical context. In asymptomatic patients, it is often best conducted via CT urography (CTU) without and with contrast, MR urography (MRU) without and with contrast, or scintigraphic evaluation with mercaptoacetyltriglycine (MAG3) imaging. For symptomatic patients, CTU without and with contrast, MRU without and with contrast, MAG3 scintigraphy, or ultrasound of the kidneys and bladder with Doppler imaging are all viable initial imaging studies. In asymptomatic pregnant patients, nonionizing imaging with US of the kidneys and bladder with Doppler imaging is preferred. Similarly, in symptomatic pregnant patients, US of the kidneys and bladder with Doppler imaging or MRU without contrast is the imaging study of choice, as both ionizing radiation and gadolinium contrast are avoided in pregnancy. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Contributors

Author

Alshihiri, Saad, primary, Amatya, Kaushalendra, additional, Argyropoulos, Christos P., additional, Berman, Nathaniel, additional, Centron, Patricia, additional, Chilcot, Joseph, additional, Christian Cornelius, Matthew, additional, Cohen, Scott D., additional, Cukor, Daniel, additional, De Geest, Sabina M., additional, Denhaerynck, Kris, additional, Dobbels, Fabienne, additional, Engel, Kristy L., additional, Farrington, Ken, additional, Foy, Capri G., additional, Graham Ford, C., additional, Gray, Nicholas A., additional, Griva, Konstadina, additional, Hooper, Stephen R., additional, Jhamb, Manisha, additional, Johansen, Kirsten L., additional, Kimmel, Paul L., additional, Kuntz, Kristin K., additional, Levy, Norman B., additional, Lew, Susie Q., additional, Mehrotra, Rajnish, additional, Moxey-Mims, Marva M., additional, Myaskovsky, Larissa, additional, Nataatmadja, Melissa S., additional, Newman, Stanton P., additional, Norton, Jenna M., additional, Parker Gregg, L., additional, Quinn, Davin K., additional, Ribaut, Janette, additional, Roumelioti, Maria-Eleni, additional, Steel, Jennifer, additional, Susan Hedayati, S., additional, Unruh, Mark L., additional, Varma, Elly, additional, Wang, Connie J., additional, Weinman, John, additional, Wetmore, James B., additional, and Won, Alice, additional

Published
2021
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22. Nonsurgical and Minimally Invasive Correction of Peritoneal Dialysis Catheter Complications

Author

Lew, Susie Q.

Subjects
Continuous ambulatory peritoneal dialysis -- Complications and side effects, Catheterization -- Complications and side effects, Peritoneal dialysis -- Complications and side effects, Iatrogenic diseases -- Care and treatment, Primary nursing -- Methods, Health
Abstract

Peritoneal dialysis catheter complications that require nonsurgical or noninvasive correction by peritoneal dialysis (PD) nurses or practitioner are reviewed. Topics reviewed include compromised PD fluid flow, pericatheter fluid leakage, mechanical integrity disruption, catheter extrusion, and exit site/tunnel complications. Key Words: Peritoneal dialysis catheter, peritoneal dialysis catheter repair, peritoneal dialysis catheter malfunction, peritoneal dialysis catheter displacement, peritoneal dialysis catheter migration, peritoneal dialysis catheter extrusion., [NC PD] 1.2 contact hours The peritoneal dialysis (PD) catheter plays a key role in the movement of PD fluid in and out of the abdominal cavity known as the [...]

Published
2021
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25. List of Contributors

Author

Abramovitz, Blaise, primary, Adu, Dwomoa, additional, Afshinnia, Farsad, additional, Agarwal, Anupam, additional, Andrews, Sarah C., additional, Appel, Gerald, additional, Bailey, James L., additional, Bakris, George L., additional, Bauer, Carolyn A., additional, Baxi, Pravir V., additional, Berns, Jeffrey S., additional, Birks, Peter, additional, Bomback, Andrew, additional, Bose, Anirban, additional, Brosius, Frank C., additional, Brown, Lee K., additional, Bushinsky, David A., additional, Busse, Laurence W., additional, Campbell, Ruth C., additional, Canney, Mark, additional, Cathro, Helen, additional, Chávez-Iñiguez, Jonathan, additional, Chawla, Lakhmir S., additional, Chen, Sheldon, additional, Chertow, Glenn M., additional, Chew, Emily Y., additional, Chonchol, Michel, additional, Clegg, Deborah J., additional, Clive, David M., additional, Clive, Pia H., additional, Cohen, Scott D., additional, Collins, Ashte' K., additional, Cooper, James E., additional, Correa-Rotter, Ricardo, additional, Cukor, Daniel, additional, Dalal, Monica, additional, Davenport, Andrew, additional, Davis, Scott, additional, Davison, Sara N., additional, Delanaye, Pierre, additional, de Zeeuw, Dick, additional, Dobre, Mirela A., additional, Drawz, Paul, additional, Ebert, Natalie, additional, Eggers, Paul, additional, Ferrè, Silvia, additional, Freedman, Barry I., additional, Furth, Susan L., additional, Gao, Bixia, additional, García-García, Guillermo, additional, Gashti, Casey N., additional, Germino, Gregory G., additional, Goldsmith, David, additional, Golestaneh, Ladan, additional, Goligorsky, Michael S., additional, Greenberg, Arthur, additional, Gregg, L. Parker, additional, Guay-Woodford, Lisa M., additional, Hamm, Lee, additional, Hart, Allyson, additional, Haselby, Danielle, additional, Hedayati, S. Susan, additional, Heerspink, Hiddo J.L., additional, Herzog, Charles A., additional, Hostetter, Thomas H., additional, House, Andrew A., additional, Hruska, Keith A., additional, Ishani, Areef, additional, Isom, Robert T., additional, James, Matthew T., additional, Jhaveri, Kenar D., additional, Johansen, Kirsten, additional, Johnson, Richard J., additional, Kang, Duk-Hee, additional, Kanno, Hiroko, additional, Kanno, Yoshihiko, additional, Karambelkar, Amrita D., additional, Karet Frankl, Fiona E., additional, Khoury, Charbel C., additional, Kimmel, Paul L., additional, Kopp, Jeffrey B., additional, Korbet, Stephen M., additional, Kruzel-Davila, Etty, additional, Kummer, Andrew, additional, LaFave, Laura, additional, Lakkis, Jay I., additional, Lerman, Lilach O., additional, Levin, Adeera, additional, Lew, Susie Q., additional, Luyckx, Valerie A., additional, Mattoo, Tej K., additional, Maynard, Sharon E., additional, McCullough, Peter A., additional, Mehrotra, Rajnish, additional, Meyer, Timothy W., additional, Mitch, William E., additional, Moe, Orson W., additional, Mohandes, Samer, additional, Moss, Alvin H., additional, Moxey-Mims, Marva, additional, Murugapandian, Sangeetha, additional, Nath, Karl A., additional, Neugarten, Joel, additional, Neyra, Javier A., additional, Nissenson, Allen R., additional, Nobakht, Ehsan, additional, Nolin, Thomas D., additional, Norris, Keith C., additional, Norton, Jenna M., additional, Nowak, Kristen L., additional, Ojo, Akinlolu O., additional, Pahl, Madeleine V., additional, Paller, Mark S., additional, Palmer, Biff F., additional, Palmer, Nicholette D., additional, Patel, Samir S., additional, Pecoits-Filho, Roberto, additional, Peitzman, Steven J., additional, Peixoto, Aldo J., additional, Pham, Phuong-Thu T., additional, Pham, Phuong-Chi T., additional, Piraino, Beth, additional, Pisoni, Roberto, additional, Rabelink, Ton, additional, Radhakrishnan, Jai, additional, Rahman, Mahboob, additional, Raj, Dominic S., additional, Ramírez-Sandoval, Juan C., additional, Rangaswami, Janani, additional, Reckelhoff, Jane F., additional, Regunathan-Shenk, Renu, additional, Reule, Scott, additional, Ronco, Claudio, additional, Rosenberg, Mark E., additional, Rosner, Mitchell H., additional, Rovin, Brad, additional, Roy-Chaudhury, Prabir, additional, Ruebner, Rebecca, additional, Rule, Andrew D., additional, Sands, Jeff M., additional, Schlanger, Lynn E., additional, Schrauben, Sarah J., additional, Seliger, Stephen, additional, Shah, Maulin, additional, Sterns, Richard H., additional, Stites, Erik, additional, Sugatani, Toshifumi, additional, Textor, Stephen C., additional, Thadhani, Ravi, additional, Thajudeen, Bijin, additional, Thakar, Surabhi, additional, Thomas, George, additional, Townsend, Raymond R., additional, Turner, Jeffrey, additional, Unruh, Mark L., additional, Urquhart, Bradley L., additional, Vassalotti, Joseph A., additional, Vaziri, Nosratola D., additional, Velasquez, Manuel T., additional, Ver Halen, Nisha, additional, Waddy, Salina P., additional, Wang, Jinwei, additional, Weber, Marc, additional, Weir, Matthew R., additional, White, Christine A., additional, Whittier, William L., additional, Williams, Matthew J., additional, Wiseman, Alexander C., additional, Wymer, David C., additional, Wymer, David T.G., additional, Yee, Jerry, additional, Zhang, Luxia, additional, Zhuang, Shougang, additional, and Ziyadeh, Fuad N., additional

Published
2020
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31. Contributors

Author

Albright, Robert C., primary, Amerling, Richard, additional, Angeli, Paolo, additional, Angelotti, Maria Lucia, additional, Antonelli, Massimo, additional, Antoniotti, Riccardo, additional, Arulkumaran, Nishkantha, additional, Asfar, Pierre, additional, Ash, Stephen R., additional, Aucella, Filippo, additional, Aucella, Francesco, additional, Ave, Samuele, additional, Bagshaw, Sean M., additional, Balaraman, Vasanthi, additional, Baldwin, Ian, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barnela, Shriganesh R., additional, Bayır, Hülya, additional, Beaulieu, Monica, additional, Bellasi, Antonio, additional, Bellomo, Rinaldo, additional, Beloncle, François, additional, Bhansali, Arjun, additional, Bihorac, Azra, additional, Billings, Frederic T., additional, Birk, Horst-Walter, additional, Bonilla-Reséndiz, Luis Ignacio, additional, Bouchard, Josée, additional, Bourke, Edmund, additional, Braitberg, George, additional, Brendolan, Alessandra, additional, Brocca, Alessandra, additional, Brophy, Patrick D., additional, Bucala, Richard, additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Busse, Laurence W., additional, Caires, Renato Antunes, additional, Caironi, Pietro, additional, Camilla, Roberta, additional, Campos, Israel, additional, Canaud, Bernard, additional, Cantaluppi, Vincenzo, additional, Martinez, Maria P., additional, Capasso, Giovambattista, additional, Carcillo, Joseph A., additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castellano, Giuseppe, additional, Catania, Matteo, additional, Cawcutt, Kelly A., additional, Cerda, Jorge, additional, Charen, Elliot, additional, Chawla, Lakhmir S., additional, Chiaramonte, Stefano, additional, Chua, Horng-Ruey, additional, Cianciaruso, Bruno, additional, Ciceri, Paola, additional, Cieslak, Jacek, additional, Clark, William R., additional, Claure-Del Granado, Rolando, additional, Clementi, Anna, additional, Co, Ivan N., additional, Coelho, Fernanda Oliveira, additional, Conte, Ferruccio, additional, Corey, Howard E., additional, Cosmai, Laura, additional, Costalonga, Elerson Carlos, additional, Costamagna, Andrea, additional, Costanzo, Maria Rosa, additional, Cozzolino, Mario, additional, Cramer, Carl H., additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Creteur, Jacques, additional, Crew, R. John, additional, da Costa e Silva, Verônica Torres, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, D'Costa, Rohit, additional, Dean, Dawson F., additional, Debiais, Charlotte, additional, de Cal, Massimo, additional, Dedhia, Paras, additional, de Grooth, Harm-Jan, additional, Dell'Aquila, Roberto, additional, Dellepiane, Sergio, additional, Dellinger, Richard Phillip, additional, Del Vecchio, Lucia, additional, Depner, Thomas A., additional, De Rosa, Silvia, additional, Deutschman, Clifford S., additional, Devarajan, Prasad, additional, Dewitte, A., additional, Di Iorio, Biagio R., additional, Di Lullo, Luca, additional, Di Micco, Lucia, additional, Di Nardo, Matteo, additional, Ding, Xiaoqiang, additional, D'Ippoliti, Fiorella, additional, Di Somma, Salvatore, additional, Doi, Kent, additional, Dries, David J., additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durand, Francois, additional, Eadon, Michael T., additional, Eckstein, Devin, additional, Egi, Moritoki, additional, Eiam-Ong, Somchai, additional, Elbers, Paul W.G., additional, Elli, Francesca, additional, Elliott, Steve, additional, Emlet, David R., additional, Endre, Zoltan, additional, Evans, Roger G., additional, Fanelli, Vito, additional, Fattahi, Fatemeh, additional, Federspiel, Christine Kinggaard, additional, Ferrada, Marcela A., additional, Ferrari, Fiorenza, additional, Fiaccadori, Enrico, additional, Fiorentino, Marco, additional, Fisher, Caleb, additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Francoz, Claire, additional, French, Craig, additional, Fuhrman, Dana Y., additional, Fumagalli, Giordano, additional, Galbusera, Miriam, additional, Gallieni, Maurizio, additional, Gammill, Hilary S., additional, Gao, Dayong, additional, Garzotto, Francesco, additional, Gatta, Giuseppe, additional, Genga, Kelly R., additional, Genovesi, Simonetta, additional, Genyk, Yuri S., additional, Geradin, Christel, additional, Gesualdo, Loreto, additional, Giavarina, Davide, additional, Giuliani, Anna, additional, Glezerman, Ilya G., additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gómez, Hernando, additional, Granata, Antonio, additional, Grandaliano, Giuseppe, additional, Grasselli, Giacomo, additional, Groeneveld, A.B. Johan, additional, Guerci, Philippe, additional, Gunnerson, Kyle J., additional, Harbord, Nikolas, additional, Harshman, Lyndsay A., additional, Hennessy, Anthony J., additional, Hill, Graham L., additional, Hobson, Charles, additional, Hohenstein, Bernd, additional, Honoré, Patrick M., additional, Horwitz, Edward, additional, Hosseinian, Leila, additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Humes, H. David, additional, Husain-Syed, Faeq, additional, Ince, Can, additional, Ing, Todd S., additional, Jacobs, Rita, additional, Jaswal, Dharmvir, additional, Jeyabalan, Arun, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Joyce, Emily, additional, Kane-Gill, Sandra L., additional, Kaplan, Lewis J., additional, Kashani, Kianoush, additional, Katz, Nevin, additional, Kellum, John A., additional, Khanna, Ramesh, additional, Kim-Campbell, Nahmah, additional, King, Joshua D., additional, Kirwan, Christopher J., additional, Kiss, Joseph E., additional, Klein, David, additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lachance, Philippe, additional, Lameire, Norbert, additional, Langer, Thomas, additional, Lankadeva, Yugeesh R., additional, Laurin, Louis-Philippe, additional, Lazzeri, Elena, additional, Leblanc, Martine, additional, Lefebvre, Joannie, additional, Lentini, Paolo, additional, Leray-Moragués, Hélène, additional, Levin, Adeera, additional, Lew, Susie Q., additional, Liapis, Helen, additional, Liu, Kathleen D., additional, Livigni, Sergio, additional, Locatelli, Francesco, additional, Lorenzin, Anna, additional, Lu, Jian-Da, additional, Lu, Renhua, additional, Lysak, Nicholas, additional, Macedo, Etienne, additional, Madan, Niti, additional, Madore, François, additional, Maerz, Linda L., additional, Maiden, Matthew J., additional, Malhotra, Rakesh, additional, Marengo, Marita, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marino, Rossella, additional, Marshall, Mark R., additional, Mårtensson, Johan, additional, Matsuura, Ryo, additional, May, Clive N., additional, Mazzone, Patrizio, additional, McCauley, Jerry, additional, McCullough, Peter A., additional, McMahon, Blaithin A., additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Menon, Madhav, additional, Meola, Mario, additional, Mérouani, Aicha, additional, Meuwly, Jean-Yves, additional, Milla, Paola, additional, Misra, Madhukar, additional, Misra, Paraish S., additional, Mizock, Barry A., additional, Modi, Jwalant R., additional, Moeckel, Gilbert, additional, Molitoris, Bruce A., additional, Morabito, Santo, additional, Mucelli, Roberto Pozzi, additional, Murray, Patrick T., additional, Murugan, Raghavan, additional, Nadim, Mitra K., additional, Nair, Devika, additional, Nalesso, Federico, additional, Neri, Mauro, additional, Nguyen, Trung C., additional, Ni, Zhaohui, additional, Noris, Marina, additional, Novick, Tessa, additional, O'Horo, John C., additional, Okusa, Mark Douglas, additional, Opal, Steven M., additional, Opdam, Helen Ingrid, additional, Ostermann, Marlies, additional, Ottaviano, Emerenziana, additional, Oudemans-van Straaten, Heleen M., additional, Overgaard-Steensen, Christian, additional, Padalino, Massimo A., additional, Panichi, Vincenzo, additional, Parameswaran, Priyanka, additional, Patel, Samir S., additional, Payen, Didier, additional, Pea, Federico, additional, Peacock, W. Frank, additional, Peart, Sandrica Young, additional, Peerapornratana, Sadudee, additional, Pelosi, Paolo, additional, Peng, Zhi-Yong, additional, Perico, Norberto, additional, Peruzzi, Licia, additional, Pesce, Francesco, additional, Pesenti, Antonio, additional, Petrucci, Ilaria, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Piano, Salvatore, additional, Pinsky, Michael R., additional, Piquilloud, Lise, additional, Pistolesi, Valentina, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Podestá, Manuel Alfredo, additional, Porta, Camillo, additional, Pozzato, Marco, additional, Prencipe, Michele, additional, Prowle, John R., additional, Puthucheary, Zudin A., additional, Qu, Lirong, additional, Rachoin, Jean-Sebastien, additional, Radhakrishnan, Jai, additional, Ranieri, V. Marco, additional, Ratanarat, Ranistha, additional, Remuzzi, Giuseppe, additional, Resnick, Shelby, additional, Rewa, Oleksa G., additional, Ricci, Zaccaria, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Rizo-Topete, Lilia M., additional, Roessler, Eric, additional, Romagnani, Paola, additional, Romagnoli, Stefano, additional, Ronco, Claudio, additional, Ronco, Federico, additional, Rosner, Mitchell H., additional, Rossetti, Emanuele, additional, Russell, James A., additional, Saab, Georges, additional, Sabatino, Alice, additional, Saboo, Sonali S., additional, Samoni, Sara, additional, Sappington, Penny Lynn, additional, Sartori, Marco, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schneider, Antoine Guillaume, additional, Schraverus, Pieter, additional, Schulte, Wibke, additional, Segoloni, Giuseppe, additional, Semler, Matthew W., additional, Sharma, Aashish, additional, Shaw, Andrew, additional, Sheth, Naitik, additional, Shukla, Ashutosh, additional, Siddall, Eric C., additional, Sievers, Theodore M., additional, Siew, Edward D., additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Singh, Pooja, additional, Smith, Loren E., additional, Soni, Sachin S., additional, Soto, Mara Serrano, additional, Spapen, Herbert D., additional, Srisawat, Nattachai, additional, Srivastava, Ajay, additional, Stellin, Giovanni, additional, Symons, Jordan M., additional, Szamosfalvi, Balazs, additional, Tai, Kian Bun, additional, Takalkar, Unmesh V., additional, Teitelbaum, Isaac, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Tonon, Marta, additional, Trepiccione, Francesco, additional, Triulzi, Darrell, additional, Tushar, Chopra, additional, Uchino, Shigehiko, additional, Valika, Ali, additional, Van Biesen, Wim, additional, Vandenberghe, Wim, additional, Vanholder, Raymond, additional, Vanmassenhove, Jill, additional, Verbine, Anton, additional, Vergano, Marco, additional, Villa, Gianluca, additional, Villeneuve, Pierre-Marc, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Virzì, Grazia Maria, additional, Visconti, Federico, additional, Visvanathan, Ravindran, additional, Van Vong, Li, additional, Walmrath, Hans-Dieter, additional, Ward, Peter A., additional, Weir, Matthew A., additional, Wen, Xiaoyan, additional, Wendon, Julia, additional, Winchester, James Frank, additional, Wong, Adrian, additional, Woodhouse, Elke L., additional, Xue, Jun, additional, Yadav, Anju, additional, Yerram, Preethi, additional, Yessayan, Lenar, additional, Yeun, Jane Y., additional, Yu, Alex W., additional, Zaccaria, Marta, additional, Zacchia, Miriam, additional, Zachariah, Teena P., additional, Zamperetti, Nereo, additional, Zampieri, Fernando G., additional, Zanco, Pierluigi, additional, Zanella, Alberto, additional, Zanoli, Luca, additional, Zappitelli, Michael, additional, Zaragoza, Jose J., additional, Zarbock, Alexander, additional, Zaroccolo, Marta, additional, Zhang, Han, additional, and Zimmer, Andrea, additional

Published
2019
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36. Improving Specialty Care Access via Telemedicine

Author

Burke, Guenevere V., primary, Osman, Kareem A., additional, Lew, Susie Q., additional, Ehrhardt, Nicole, additional, Robie, Andrew C., additional, Amdur, Richard L., additional, Martin, Lisa W., additional, and Sikka, Neal, additional

Published
2023
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38. Keys to Driving Implementation of the New Kidney Care Models

Author

Kshirsagar, Abhijit V., primary, Weiner, Daniel E., additional, Mendu, Mallika L., additional, Liu, Frank, additional, Lew, Susie Q., additional, O’Neil, Terrence J., additional, Bieber, Scott D., additional, White, David L., additional, Zimmerman, Jonathan, additional, and Mohan, Sumit, additional

Published
2022
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41. Edelman Revisited: Concepts, Achievements, and Challenges

Author

Rohrscheib, Mark, primary, Sam, Ramin, additional, Raj, Dominic S., additional, Argyropoulos, Christos P., additional, Unruh, Mark L., additional, Lew, Susie Q., additional, Ing, Todd S., additional, Levin, Nathan W., additional, and Tzamaloukas, Antonios H., additional

Published
2022
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44. List of Contributors

Author

Afshinnia, Farsad, primary, Agarwal, Anupam, additional, Appel, Gerald B., additional, Bagby, Susan P., additional, Bailey, James L., additional, Bakris, George L., additional, Barrett, Brendan J., additional, Bauer, Carolyn A., additional, Berl, Tomas, additional, Berns, Jeffrey S., additional, Bomback, Andrew, additional, Bose, Anirban, additional, Brosius, Frank C., additional, Brown, Lee K., additional, Bushinsky, David A., additional, Busse, Laurence W., additional, Campbell, Ruth C., additional, Cathro, Helen, additional, Chawla, Lakhmir S., additional, Chen, Sheldon, additional, Chertow, Glenn M., additional, Chew, Emily, additional, Chonchol, Michel, additional, Clive, David M., additional, Cohen, Debbie L., additional, Cohen, Lewis M., additional, Cohen, Scott D., additional, Collins, Ashte’ K., additional, Combs, Sara, additional, Correa-Rotter, Ricardo, additional, Cukor, Daniel, additional, Dalal, Monica, additional, Dancik, Tavis, additional, Davenport, Andrew, additional, Davison, Sara, additional, Zeeuw, Dick de, additional, Delanaye, Pierre, additional, Dharia, Sushma M., additional, Dobre, Mirela A., additional, Drawz, Paul, additional, Dreisbach, Albert W., additional, Emmett, Michael, additional, Fanton, John H., additional, Felsenfeld, Arnold J., additional, Fernandez, Hilda, additional, Flessner, Michael F., additional, Freedman, Barry I., additional, Fruchter, Yvette, additional, Furth, Susan L., additional, García-García, Guillermo, additional, Germain, Michael J., additional, Germino, Gregory G., additional, Goligorsky, Michael S., additional, Greenberg, Arthur, additional, Guay-Woodford, Lisa M., additional, Hawkins, Katrina, additional, Herzog, Charles A., additional, Holley, Jean L., additional, Hostetter, Thomas H., additional, House, Andrew A., additional, Hruska, Keith A., additional, Huan, Yonghong, additional, Ibrahim, Hassan N., additional, Imran, Nashat, additional, Iñiguez, Jonathan Chávez, additional, Isom, Robert T., additional, Jablonski, Kristen L., additional, Jhaveri, Kenar D., additional, Johansen, Kirsten, additional, Johnson, Richard J., additional, Junghare, Milind Y., additional, Kang, Duk-Hee, additional, Karadsheh, Feras F., additional, Kari, Jameela, additional, Kasiske, Bertram L., additional, Khoury, Charbel C., additional, Kimmel, Paul L., additional, Kopp, Jeffrey B., additional, Kummer, Andrew, additional, Heerspink, Hiddo J.Lambers, additional, Lerman, Lilach O., additional, Levin, Adeera, additional, Levine, Barton S., additional, Lew, Susie Q., additional, Mandayam, Sreedhar, additional, Mattoo, Tej K., additional, Maynard, Sharon E., additional, Meyer, Timothy W., additional, Mitch, William E., additional, Moss, Alvin H., additional, Moxey-Mims, Marva, additional, Muntner, Paul, additional, Murray, Anne M., additional, Nath, Karl A., additional, Neugarten, Joel, additional, No, Gloria, additional, Pahl, Madeleine V., additional, Paller, Mark S., additional, Palmer, Biff F., additional, Parfrey, Patrick S., additional, Patel, Samir S., additional, Pecoits-Filho, Roberto, additional, Peitzman, Steven J., additional, Peixoto, Aldo J., additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Rabelink, Ton J., additional, Radhakrishnan, Jai, additional, Raed, Anas, additional, Raj, Dominic S., additional, Ramirez-Sandoval, Juan Carlos, additional, Reckelhoff, Jane F., additional, Ronco, Claudio, additional, Rosenberg, Mark E., additional, Rosner, Mitchell H., additional, Rovin, Brad, additional, Roy-Chaudhury, Prabir, additional, Ruebner, Rebecca, additional, Rule, Andrew D., additional, Sands, Jeff M., additional, Scheinman, Steven J., additional, Schlanger, Lynn E., additional, Seifert, Michael E., additional, Seliger, Stephen, additional, Singh, Ajay K., additional, Stendahl, John C., additional, Surendran, Kameswaran, additional, Textor, Stephen C., additional, Thadhani, Ravi I., additional, Townsend, Raymond R., additional, Unruh, Mark L., additional, Vassalotti, Joseph A., additional, Vaziri, Nosratola D., additional, Velasquez, Manuel T., additional, Ver Halen, Nisha, additional, Wang, Connie J., additional, Wanner, Christoph, additional, Weber, Marc, additional, Weir, Matthew R., additional, Wing, Maria R., additional, Winn, Michelle P., additional, Wymer, David C., additional, Yee, Jerry, additional, and Ziyadeh, Fuad N., additional

Published
2015
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