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Your search keyword '"Li, Cai-Lan"' showing total 14 results
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14 results on '"Li, Cai-Lan"'

5. Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo

Author

Li, Cai-Lan, primary, Tan, Li-Hua, additional, Wang, Yong-Fu, additional, Luo, Chao-Dan, additional, Chen, Han-Bin, additional, Lu, Qiang, additional, Li, Yu-Cui, additional, Yang, Xiao-Bo, additional, Chen, Jian-Nan, additional, Liu, Yu-Hong, additional, Xie, Jian-Hui, additional, and Su, Zi-Ren, additional

Published
2019
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9. Pharmacokinetic Interaction between Magnolol and Piperine in Rats

Author

Chen, Xiao-Ying, primary, Yang, Guang-Hua, additional, Li, Cai-Lan, additional, Yu, Xiu-Ting, additional, Wang, Xiu-Fen, additional, Zheng, Yi-Feng, additional, Xie, Jian-Hui, additional, Lai, Xiao-Ping, additional, Su, Zi-Ren, additional, Liang, Yong-Zhuo, additional, and Lin, Ji, additional

Published
2016
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14. Protective Effect of SFE-CO 2 of Ligusticum chuanxiong Hort Against d-Galactose-Induced Injury in the Mouse Liver and Kidney.

Author

Mo ZZ, Liu YH, Li CL, Xu LQ, Wen LL, Xian YF, Lin ZX, Zhan JY, Chen JN, Xu FF, and Su ZR

Subjects
Aging pathology, Alanine Transaminase blood, Animals, Antioxidants pharmacology, Aspartate Aminotransferases blood, Blood Urea Nitrogen, Body Weight drug effects, Creatinine blood, Cyclooxygenase 2 metabolism, Galactose, Gas Chromatography-Mass Spectrometry, Gene Expression Regulation drug effects, Inflammation pathology, Inhibitory Concentration 50, Kidney drug effects, Kidney enzymology, Kidney pathology, Lipid Peroxidation drug effects, Liver drug effects, Liver enzymology, Liver pathology, Male, Mice, NF-kappa B metabolism, Nitric Oxide Synthase Type II metabolism, Organ Specificity, Plant Extracts chemistry, Carbon Dioxide chemistry, Chromatography, Supercritical Fluid, Kidney injuries, Ligusticum chemistry, Liver injuries, Plant Extracts pharmacology, Protective Agents pharmacology
Abstract

This study was designed to explore how supercritical fluid CO 2 extract of Ligusticum chuanxiong Hort (CX) protects mouse liver and kidney from d-galactose-induced injury. The antioxidant capacity of CX was confirmed both in vitro and in vivo. The d-galactose-induced malondialdehyde increase was attenuated by CX, as well as the increase in aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen, and creatinine level. In addition, the activities of antioxidant enzymes were markedly renewed, and the gene expressions of these enzymes were upregulated in CX groups. The results of histological analysis suggested that CX could effectively attenuate the d-galactose-induced structure damage. Furthermore, results of Western blotting analysis showed that CX significantly inhibited the upregulation of nuclear factor protein expression caused by d-galactose. In conclusion, CX could attenuate the liver and kidney injury in d-galactose-treated mice, and the mechanism might be associated with attenuating oxidative stress and inflammatory response.

Published
2017
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