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Multi-modality magnetic resonance imaging (MRI) can provide complementary information for computer-aided diagnosis. Traditional deep learning algorithms are suitable for identifying specific anatomical structures segmenting lesions and classifying diseases with magnetic resonance images. However, manual labels are limited due to high expense, which hinders further improvement of model accuracy. Self-supervised learning (SSL) can effectively learn feature representations from unlabeled data by pre-training and is demonstrated to be effective in natural image analysis. Most SSL methods ignore the similarity of multi-modality MRI, leading to model collapse. This limits the efficiency of pre-training, causing low accuracy in downstream segmentation and classification tasks. To solve this challenge, we establish and validate a multi-modality MRI masked autoencoder consisting of hybrid mask pattern (HMP) and pyramid barlow twin (PBT) module for SSL on multi-modality MRI analysis. The HMP concatenates three masking steps forcing the SSL to learn the semantic connections of multi-modality images by reconstructing the masking patches. We have proved that the proposed HMP can avoid model collapse. The PBT module exploits the pyramidal hierarchy of the network to construct barlow twin loss between masked and original views, aligning the semantic representations of image patches at different vision scales in latent space. Experiments on BraTS2023, PI-CAI, and lung gas MRI datasets further demonstrate the superiority of our framework over the state-of-the-art. The performance of the segmentation and classification is substantially enhanced, supporting the accurate detection of small lesion areas. The code is available at https://github.com/LinxuanHan/M2-MAE.

Magnetic resonance imaging (MRI) using hyperpolarized noble gases provides a way to visualize the structure and function of human lung, but the long imaging time limits its broad research and clinical applications. Deep learning has demonstrated great potential for accelerating MRI by reconstructing images from undersampled data. However, most existing deep conventional neural networks (CNN) directly apply square convolution to k-space data without considering the inherent properties of k-space sampling, limiting k-space learning efficiency and image reconstruction quality. In this work, we propose an encoding enhanced (EN2) complex CNN for highly undersampled pulmonary MRI reconstruction. EN2 employs convolution along either the frequency or phase-encoding direction, resembling the mechanisms of k-space sampling, to maximize the utilization of the encoding correlation and integrity within a row or column of k-space. We also employ complex convolution to learn rich representations from the complex k-space data. In addition, we develop a feature-strengthened modularized unit to further boost the reconstruction performance. Experiments demonstrate that our approach can accurately reconstruct hyperpolarized 129Xe and 1H lung MRI from 6-fold undersampled k-space data and provide lung function measurements with minimal biases compared with fully-sampled image. These results demonstrate the effectiveness of the proposed algorithmic components and indicate that the proposed approach could be used for accelerated pulmonary MRI in research and clinical lung disease patient care.

In this work, we study stochastic non-cooperative games, where only noisy black-box function evaluations are available to estimate the cost function for each player. Since each player's cost function depends on both its own decision variables and its rivals' decision variables, local information needs to be exchanged through a center/network in most existing work for seeking the Nash equilibrium. We propose a new stochastic distributed learning algorithm that does not require communications among players. The proposed algorithm uses simultaneous perturbation method to estimate the gradient of each cost function, and uses mirror descent method to search for the Nash equilibrium. We provide asymptotic analysis for the bias and variance of gradient estimates, and show the proposed algorithm converges to the Nash equilibrium in mean square for the class of strictly monotone games at a rate faster than the existing algorithms. The effectiveness of the proposed method is buttressed in a numerical experiment.

Coronal mass ejections (CMEs) and coronal jets are two types of common solar eruptive phenomena, which often independently happen at different spatial scales. In this work, we present a stereoscopic observation of a large-scale CME flux rope arising from an unwinding blowout jet in a multipolar complex magnetic system. Based on a multi-band observational analysis, we find that this whole event starts with a small filament whose eruption occurs at a coronal geyser site after a series of homologous jets. Aided by magnetic field extrapolations, it reveals that the coronal geyser site forms above an elongate opposite-polarity interface, where the emergence-driven photospheric flux cancellation and repetitive reconnection are responsible for those preceding recurrent jets and also contribute to the ultimate filament destabilization. By interacting with overlying fields, the erupting filament breaks one of its legs and results in an unwinding blowout jet. Our estimation suggests that around 1.4$-$2.0 turns of twist release in its jet spire. This prominent twist transport in jet spire rapidly creates a newborn larger-scale flux rope from the jet base to a remote site. Soon after its formation, this large-scale flux rope erupts towards the outer coronae causing an Earth-directed CME. In its source region, two sets of distinct post-flare loops form in succession, indicating this eruption involves two-stage of flare magnetic reconnection. This work not only reveals a real magnetic coupling process between different eruptive activities but provides a new hint for understanding the creation of large-scale CME flux ropes during the solar eruption., Comment: Accepted in February 10, 2021 Submitted to ApJ

We consider a simulation optimization problem for a context-dependent decision-making. A Gaussian mixture model is proposed to capture the performance clustering phenomena of context-dependent designs. Under a Bayesian framework, we develop a dynamic sampling policy to efficiently learn both the global information of each cluster and local information of each design for selecting the best designs in all contexts. The proposed sampling policy is proved to be consistent and achieve the asymptotically optimal sampling ratio. Numerical experiments show that the proposed sampling policy significantly improves the efficiency in context-dependent simulation optimization.