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225 results on '"Li, Jieping"'

13. HDAC I/IIb selective inhibitor purinostat mesylate in relapsed and refractory diffuse large B-cell lymphoma: A single agent phase IIa trial.

Author

Chen, Lijuan, primary, Yang, Linyu, additional, Wang, Jie, additional, Liang, Rui, additional, Li, He, additional, Liu, Mengke, additional, Wen, Yi, additional, Liu, Lin, additional, Tang, Xiaoqiong, additional, Li, Jieping, additional, Lai, Xun, additional, Wu, Huijing, additional, Li, Yajun, additional, Huang, Shihua, additional, Yang, Lihua, additional, Tan, Ke, additional, Wang, Li, additional, Niu, Ting, additional, and Zhao, Weili, additional

Published
2024
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15. Clinical Characteristics and Prognostic Influence Factors of Patients with AIDS-related Malignant Tumor

Author

LEI Haike, LI Xiaosheng, LI Jieping, LIU Jun, XIAO Chunyan, WANG Ying, ZHANG Wei, LIU Yao, and WU Yongzhong

Subjects
hiv, malignant tumor, clinical features, survival, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Objective To analyze the clinical characteristics and survival prognosis of patients with AIDS-related malignant tumor. Methods We retrospectively analyzed the data of 354 patients with AIDS-related malignant tumor. Univariate analysis was conducted by Log rank test and multivariate analysis was conducted by Cox proportional risk regression model. Results The average age of the patients was 54.10±12.96 years old. The ratio of male to female patients was 2.1:1. The number of patients with AIDS complicated with lymphoma was the most, accounting for 28.25%. The 1-, 3- and 5-year survival rates were 78.48%, 62.13% and 55.31%, respectively. Univariate analysis showed that there were statistical differences in prognosis of patients with different types of malignant tumor, age, gender, medical insurance type, number of admissions after diagnosis of AIDS, average length of stay, radiotherapy or not, leaving hospital according to medical advice. Multivariate analysis showed that gender, number of admissions after diagnosis of AIDS, average length of stay, proportion of out-of-pocket and leaving hospital according to medical advice were independent risk factors affecting the survival and prognosis of patients. Conclusion AIDS is easily complicated with lymphoma, lung cancer and cervical cancer. The patients received insufficient anti-tumor courses in hospital.

Published
2022
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16. A genome‐wide association study uncovers a ZmRap2.7‐ZCN9/ZCN10 module to regulate ABA signalling and seed vigour in maize.

Author

Guo, Shasha, Ai, Junmin, Zheng, Nannan, Hu, Hairui, Xu, Zhuoyi, Chen, Quanquan, Li, Li, Liu, Yunjun, Zhang, Hongwei, Li, Jieping, Pan, Qingchun, Chen, Fanjun, Yuan, Lixing, Fu, Junjie, Gu, Riliang, Wang, Jianhua, and Du, Xuemei

Subjects
TRANSCRIPTION factors, FLOWERING time, CROP yields, ABSCISIC acid, ROOT development
Abstract

Summary: Seed vigour, including rapid, uniform germination and robust seedling establishment under various field conditions, is becoming an increasingly essential agronomic trait for achieving high yield in crops. However, little is known about this important seed quality trait. In this study, we performed a genome‐wide association study to identify a key transcription factor ZmRap2.7, which regulates seed vigour through transcriptionally repressing expressions of three ABA signalling genes ZmPYL3, ZmPP2C and ZmABI5 and two phosphatidylethanolamine‐binding genes ZCN9 and ZCN10. In addition, ZCN9 and ZCN10 proteins could interact with ZmPYL3, ZmPP2C and ZmABI5 proteins, and loss‐of‐function of ZmRap2.7 and overexpression of ZCN9 and ZCN10 reduced ABA sensitivity and seed vigour, suggesting a complex regulatory network for regulation of ABA signalling mediated seed vigour. Finally, we showed that four SNPs in ZmRap2.7 coding region influenced its transcriptionally binding activity to the downstream gene promoters. Together with previously identified functional variants within and surrounding ZmRap2.7, we concluded that the distinct allelic variations of ZmRap2.7 were obtained independently during maize domestication and improvement, and responded separately for the diversities of seed vigour, flowering time and brace root development. These results provide novel genes, a new regulatory network and an evolutional mechanism for understanding the molecular mechanism of seed vigour. [ABSTRACT FROM AUTHOR]

Published
2024
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17. A simple and efficient Agrobacterium tumefaciens mediated transgenic system for tetraploid potato cultivar Desiree

Author

Xu, Chunjiang, primary, Qi, Lipan, additional, Chang, Shiwei, additional, Yuan, Pingping, additional, Zhang, Zhenxin, additional, Shan, Youjiao, additional, Magembe, Eric, additional, Kear, Philip, additional, Feng, Yan, additional, Li, Yafei, additional, Ji, Yihong, additional, Wang, Lei, additional, and Li, Jieping, additional

Published
2024
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18. Trade‐offs between the accumulation of cuticular wax and jasmonic acid‐mediated herbivory resistance in maize

Author

Liu, Jiong, primary, Li, Lu, additional, Xiong, Zhilong, additional, Robert, Christelle A.M., additional, Li, Baozhu, additional, He, Shan, additional, Chen, Wenjie, additional, Bi, Jiasheng, additional, Zhai, Guanqing, additional, Guo, Siyi, additional, Zhang, Hui, additional, Li, Jieping, additional, Zhou, Shutang, additional, Zhang, Xi, additional, and Song, Chun‐Peng, additional

Published
2024
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20. Antibody responses to SARS‐CoV‐2 Omicron infection in patients with hematological malignancies: A multicenter, prospective cohort study

Author

Li, Jun, primary, Liu, Yi, additional, Wei, Xia, additional, Liu, Zhanshu, additional, Yang, Zailiang, additional, Liu, Ling, additional, Zhou, Meiyu, additional, Xu, Guofa, additional, Chen, Lanting, additional, Ding, Yao, additional, Lei, Haike, additional, Yang, Zailin, additional, Chen, Shuang, additional, Zhang, Xiaomei, additional, Tang, Yifeng, additional, Fu, Huihui, additional, He, Sanxiu, additional, Guo, Bingling, additional, Liang, Xiping, additional, Zhang, Lingqian, additional, Zhang, Wenjun, additional, Wu, Jing, additional, Wang, Chaoyu, additional, Hu, Chongling, additional, Hu, Renzhi, additional, Luo, Xin, additional, Quan, Xi, additional, Zeng, Chensi, additional, Liang, Shunsi, additional, Liu, Tingting, additional, Lv, Jing, additional, Luo, Qin, additional, Qi, Qin, additional, Xu, Luxiang, additional, Xiong, Yan, additional, Liu, Jueyin, additional, Huang, Dehong, additional, Xiao, Chunyan, additional, Liu, Jun, additional, Yang, Tao, additional, Xiang, Ying, additional, Li, Qiying, additional, Nan, Yingyu, additional, Li, Jieping, additional, Zhang, Yong, additional, Wu, Yongzhong, additional, and Liu, Yao, additional

Published
2023
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32. Efficacy and Safety of Zanubrutinib Combined with R-CHOP Regimen in the Treatment of Newly Diagnosed Diffuse Large B-Cell Lymphoma with Extranodal Involvement: A Single-Arm, Prospective Phase II Trial

Author

Yang, Tao, primary, Li, Jun, additional, Zhang, Wenjun, additional, Guo, Bingling, additional, Hu, Chongling, additional, Quan, Xi, additional, Zeng, Chensi, additional, Ding, Yao, additional, Huang, Dehong, additional, Xiao, Chunyan, additional, Liu, Jun, additional, Wu, Jing, additional, Wang, Chaoyu, additional, Liang, Xiping, additional, Zhang, Lingqian, additional, Yang, Zailin, additional, Liang, Shunsi, additional, Hu, Renzhi, additional, Liu, Tingting, additional, Li, Qiying, additional, Li, Jieping, additional, Nan, Yingyu, additional, Xiang, Ying, additional, and Liu, Yao, additional

Published
2022
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33. Clinical Characteristics and Outcomes of Newly Diagnosed Patients with HIV-Associated Aggressive B-Cell NHL in China

Author

Wang, Chaoyu, primary, Liu, Jun, additional, Guo, Bingling, additional, Hu, Renzhi, additional, Liu, Tingting, additional, Wu, Jing, additional, Ding, Yao, additional, Hu, Chongling, additional, Liang, Shunsi, additional, Xiao, Chunyan, additional, Huang, Dehong, additional, Yang, Tao, additional, Zhang, Wenjun, additional, Yang, Zailin, additional, Li, Jieping, additional, Nan, Yingyu, additional, Li, Qiying, additional, Xiang, Ying, additional, and Liu, Yao, additional

Published
2022
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34. Efficacy and Safety of Polatuzumab Vedotin in Combination with Rituximab Plus Bendamustine in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Single Center Analysis of Pola Compassionate Use Program (CUP) in China

Author

Yang, Tao, primary, Li, Jun, additional, Zhang, Lingqian, additional, Hu, Renzhi, additional, Wu, Jing, additional, Ding, Yao, additional, Liang, Xiping, additional, Quan, Xi, additional, Hu, Chongling, additional, Zhang, Wenjun, additional, Guo, Bingling, additional, Wang, Chaoyu, additional, Li, Qiying, additional, Li, Jieping, additional, Nan, Yingyu, additional, Xiang, Ying, additional, and Liu, Yao, additional

Published
2022
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35. A novel germline HAVCR2 (TIM-3) compound heterozygous mutation is related to hemophagocytic lymphohistiocytic syndrome in EBV-positive peripheral T-cell lymphoma (NOS) with down-regulated TIM-3 signaling

Author

Zhang, Yang, primary, Wang, Zhihua, additional, Hu, Guoyu, additional, Li, Jieping, additional, Chen, Yongheng, additional, Jiang, Yi, additional, Zhong, Haiying, additional, Liu, Xianling, additional, Hu, Chunhong, additional, Peng, Honglin, additional, Xu, Yunxiao, additional, Cheng, Zhao, additional, and Zhang, Guangsen, additional

Published
2022
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37. A reductase in the lipid metabolism at cross roads between cuticular wax production and jasmonic acid-mediated defenses in maize

Author

Liu, Jiong, primary, Li, Lu, additional, Robert, Christelle AM, additional, Li, Baozhu, additional, He, Shan, additional, Xiong, Zhilong, additional, Chen, Wenjie, additional, Bi, Jiasheng, additional, Zhai, Guanqing, additional, Guo, Siyi, additional, Zhang, Hui, additional, Li, Jieping, additional, Zhou, Shutang, additional, Zhang, Xi, additional, and Song, Chun-Peng, additional

Published
2022
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38. Clinical applicability of targeted next-generation sequencing for precision medicine in diffuse large B-cell lymphoma.

Author

Huang, Dehong, primary, Liu, Yao, additional, Li, Jieping, additional, Yang, Tao, additional, Liu, Jun, additional, Xiao, Chunyan, additional, Guo, Bingling, additional, Wu, Jing, additional, Liang, Xiping, additional, Zhang, Wenjun, additional, Luo, Xin, additional, Zhang, Lingqian, additional, Xiang, Ying, additional, Li, Qiying, additional, Nan, Yingyu, additional, Wang, Xiaoxuan, additional, Du, Furong, additional, and Song, Chao, additional

Published
2022
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41. The maize single-nucleus transcriptome comprehensively describes signaling networks governing movement and development of grass stomata

Author

Sun, Guiling, primary, Xia, Mingzhang, additional, Li, Jieping, additional, Ma, Wen, additional, Li, Qingzeng, additional, Xie, Jinjin, additional, Bai, Shenglong, additional, Fang, Shanshan, additional, Sun, Ting, additional, Feng, Xinlei, additional, Guo, Guanghui, additional, Niu, Yanli, additional, Hou, Jingyi, additional, Ye, Wenling, additional, Ma, Jianchao, additional, Guo, Siyi, additional, Wang, Hongliang, additional, Long, Yu, additional, Zhang, Xuebin, additional, Zhang, Junli, additional, Zhou, Hui, additional, Li, Baozhu, additional, Liu, Jiong, additional, Zou, Changsong, additional, Wang, Hai, additional, Huang, Jinling, additional, Galbraith, David W, additional, and Song, Chun-Peng, additional

Published
2022
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43. Clinical Characteristics and Outcomes of Newly Diagnosed Patients with Human Immunodeficiency Virus-Associated Lymphoma Administered Highly Active Antiretroviral Therapy: Central and Western China Aids Lymphoma League 001 Study (cw-CALL 001)

Author

Wang, Chaoyu, primary, Liu, Jun, additional, Lei, Haike, additional, Li, Yu, additional, Wu, Jian, additional, Guo, Bingling, additional, Hu, Renzhi, additional, Liu, Tingting, additional, Wu, Jing, additional, Ding, Yao, additional, Hu, Chongling, additional, Liang, Shunsi, additional, Xiao, Chunyan, additional, Liang, Xiping, additional, Huang, Dehong, additional, Yang, Tao, additional, Zhang, Wenjun, additional, Yang, Zailin, additional, Li, Jieping, additional, Nan, Yingyu, additional, Li, Qiying, additional, Xiang, Ying, additional, Wu, Yongzhong, additional, and Liu, Yao, additional

Published
2022
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44. Clinical characteristics and outcomes of newly diagnosed patients with HIV‐associated aggressive B‐cell NHL in China.

Author

Wang, Chaoyu, Liu, Jun, Lei, Haike, Li, Yu, Wu, Jian, Guo, Bingling, Hu, Renzhi, Liu, Tingting, Wu, Jing, Ding, Yao, Hu, Chongling, Liang, Shunsi, Xiao, Chunyan, Liang, Xiping, Huang, Dehong, Yang, Tao, Zhang, Wenjun, Yang, Zailin, Li, Jieping, and Nan, Yingyu

Subjects
RITUXIMAB, NON-Hodgkin's lymphoma, TREATMENT effectiveness, LACTATE dehydrogenase, PROGNOSIS, CANCER hospitals
Abstract

Little is known about the incidence, clinical characteristics and prognostic factors in HIV associated lymphoma as these are less common than HIV‐negative lymphoma in China. Currently, there are no standard guidelines for treatment of these patients. Therefore, we performed a study to analyse the clinical characteristics and outcomes of newly diagnosed HIV‐associated aggressive B‐cell non‐Hodgkin's lymphoma (NHL) patients in Chongqing University Cancer Hospital (CUCH). Totally 86 newly diagnosed HIV‐associated aggressive B‐cell NHL patients in CUCH, southwest China, from July 2008 to August 2021, were analysed. In the entire cohort, median age was 48 years (range, 23–87 years), and more patients were male (87.2%). Most patients had elevated lactate dehydrogenase (LDH) (82.6%), advanced ann arbor stage (80.2%) and high IPI score (IPI score, 3–5) (62.7%) at diagnosis. Median CD4+ T‐cell count at diagnosis was 191/μl (range, 4–1022), 84 patients (97.7%) were on combination antiretroviral therapy (cART) at lymphoma diagnosis. In DLBCL patients, cox multivariate analysis showed that age ≥ 60 (HR = 2.251, 95%CI 1.122–4.516; p = 0.012), elevated LDH (HR = 4.452, 95%CI 1.027–19.297; p = 0.041) and received less than two cycles of chemotherapy (HR = 0.629, 95%CI 0.589–1.071; p = 0.012) were independent risk factors for adverse prognosis based on PFS. Age ≥ 60 (HR = 3.162, 95%CI 1.500–6.665; p = 0.002) and received less than two cycles of chemotherapy (HR = 0.524, 95%CI 0.347–0.791; p = 0.002) were also independent risk factor for adverse prognosis based on OS. In BL patients, cox multivariate analysis showed that elevated LDH and received less than two cycles of chemotherapy were independent risk factors for adverse prognosis. In the DLBCL group, median PFS times in the received rituximab and no received rituximab groups were not reached and 12 months, respectively (p = 0.006). Median OS times were not reached and 36 months, respectively (p = 0.021). In the BL group, median PFS times in the received rituximab and no received rituximab groups were not reached and 4.8 months, respectively (p = 0.046). Median OS times were not reached and 10.1 months, respectively (p = 0.035). Overall, these data indicated that standardized anti‐lymphoma therapy and rituximab administration were significantly associated with improved outcomes in patients with HIV‐associated DLBCL and BL. [ABSTRACT FROM AUTHOR]

Published
2022
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47. Additional file 1 of A simple method for the application of exogenous phytohormones to the grass leaf base protodermal zone to improve grass leaf epidermis development research

Author

Li, Jieping, Feng, Xinlei, and Xie, Jinjin

Abstract

Additional file 1: Figure S1. The development pathway of stomata in the second leaf at 7 days after sowing maize seedling. (A) Large scale confocal images of maize leaf protoderm. (B-F) Series events of stomata development. Figure S2. The phenotype of wheat and maize seedlings treated with different concentration of 2,4-D. (A) Wheat seedlings treated with different concentration 2,4-D (4 �� 10-3~4 �� 10-1 mg/ml). (B) Confocal images of maize leaf protoderm treated with different concentrations of 2,4-D (4 �� 10-3~4 �� 10-1 mg/ml). Scale bar = 20 um. (C) Maize seedlinggs treated with different concentration 2,4-D (0.4-40 mg/ml). The white bar in A and C represents 1 cm.

Published
2021
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50. PES1 promotes breast cancer by differentially regulating ERα and ERβ

Author

Cheng, Long, Li, Jieping, Han, Yongjian, Lin, Jing, Niu, Chang, Zhou, Zhichao, Yuan, Bin, Huang, Ke, Li, Jiezhi, Jiang, Kai, Zhang, Hao, Ding, Lihua, Xu, Xiaojie, and Ye, Qinong

Subjects
Genetic transcription, Estrogen, Breast cancer, Health care industry
Abstract

The initiation of breast cancer is associated with increased expression of tumor-promoting estrogen receptor α (ERα) protein and decreased expression of tumor-suppressive ERβ protein. However, the mechanism underlying this process [...]

Published
2012
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