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The theory of menstrual axis can be traced back to Neijing and matured in modern times. Predecessors， such as professor Luo Yuankai and professor Yang Jialin systematically proposed that “kidney-Tiangui-Chongren-uterus” is the main axis of menstruation， which has been fully recognized by the experts in this field.“Pivot movement” is the core academic thought of Huang Yuanyu， a famous doctor in Qing dynasty， emphasizing the important influence of Qi ascending and descending movement in Zhongtu on human physiology and pathology. Based on the theory of “pivot movement” proposed by Huang Yuanyu and the elaboration of traditional Chinese medicine for menstruation， the authors tentatively proposed that the “spleen-liver-Chongren-uterus menstrual axis” is the key axis of the generation and regulation of menstruation in women of childbearing age. They also shared the experience of treating menstrual diseases based upon the spleen and spleen-liver theories， aiming to provide theorectical basis for the prevention and treatment of menstrual diseases.

Microwave thermal therapy (MWTT) is a novel clinical treatment of tumors via inducing thermal effect and anti‐tumor immune response, exhibiting advantages of deep penetration, minimal invasion, and high heat conversion efficiency. However, effective ablation is difficult to cover the entire tumor area, and heat‐shock protein 90 (HSP90) is often upregulated after ablation to generate heat tolerance of sublethal tumors and weaken the induced antitumor immune effect, resulting in a high rate of tumor recurrence and metastasis. Herein, a multifunctional nanoregulator of metal phenolic network‐coated ZnS (ZnS@Ga‐tannic acid, ZGT) is proposed to release H2S for synergically enhancing MWTT. Under the costimulation of MW radiation and acidic tumor microenvironment, ZGT can improve the MW thermal effects of tumors to promote thermal damage and release H2S to induce tumor apoptosis. The released H2S can also inhibit the production of ATP and then downregulate the expression of HSP90, strengthening the activated systemic antitumor immune response after ablation. This nanoregulator provides a new way for achieving compensation effect for MWTT. The strategy of H2S gas to downregulate HSP90 and positively regulate antitumor immune response introduces a novel direction for reducing the risk of tumor recurrence and metastasis after thermal therapy. [ABSTRACT FROM AUTHOR]

Precise individual tree or sample-based inventories derived from 3D point cloud data of mobile laser scanning can improve our comprehensive understanding of the structure, function, resilience, biodiversity, and ecosystem services of urban forests. This study assessed the performance of a handheld laser scanning system (HLS) for the extraction of tree position, diameter at breast height (DBH), and tree height (H) in an urban area. A total of 2083 trees of 13 species from 34 plots were analyzed. The results showed that the registration of tree positions using ground control points (GCPs) demonstrated high accuracy, with errors consistently below 0.4 m, except for a few instances. The extraction accuracy of DBH for all trees and individual species remained consistently high, with a total root mean square error (RMSE) of 2.06 cm (6.89%) and a bias of 0.62 cm (2.07%). Notably, broad-leaved trees outperformed coniferous trees, with RMSE and bias values of 1.86 cm (6%) and 0.76 cm (2.46%), respectively, compared to 2.54 cm (9.46%) and 0.23 cm (0.84%), respectively. The accuracy of H extraction varied significantly among different species, with R2 values ranging from 0.65 to 0.92. Generally, both DBH and H were underestimated compared to ground measurements. Linear mixed-effects models (LMEs) were applied to evaluate factors affecting the performance of HLS with the plot as a random factor. LME analysis revealed that plant type and terrain significantly influenced the accuracy of DBH and H derived from HLS data, while other fixed factors such as plot area, tree density, and trajectory length showed no significance. With a large sample size, we concluded that the HLS demonstrated sufficient accuracy in extracting individual tree parameters in urban forests. [ABSTRACT FROM AUTHOR]

Protected areas (PAs) are an important estate for sustainable development. Children in PAs are of particular concern, as they are potential future stakeholders of this estate, yet they may be the ones affected the most by the conservation and development programs in PAs. However, knowledge on children in PAs has been very limited, which threatens the probability of the success of both nature conservation and sustainable development. In this paper, we present the findings from a questionnaire survey targeted at schoolchildren in China's PAs. Our sample consisted of 41 primary schools across China. We looked at 22 indexes of the sample, inferred the conditions in the whole PAs using an exact binomial test, and compared them with those in other rural or urban areas in China. We found that schoolchildren in PAs are substantially disadvantaged in terms of many indexes, both in school and at home. We discuss possible reasons, link these results to Sustainable Development Goals (SDGs), and discuss some policy implications. With this preliminary study, we hope to stimulate additional research on the conditions of children in PAs and their potential implications for sustainable development. [ABSTRACT FROM AUTHOR]