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158 results on '"Li, Xiangqun"'

7. Glycan-Based Cellular Communication: Techniques for Carbohydrate-Protein Interactions

Author

Peng George Wang, Cheng Ma, Shukkoor Muhammed Kondengaden, Eugene Joeh, Zak Vilen, Timothy O'Leary, Mia L. Huang, Jeffrey C. Gildersleeve, John Faulkner, Xuehong Song, Lianchun Wang, James Hooper, Yuan Guo, Dejian Zhou, Zachary Klamer, Brian Haab, Abdul Rehman, Lei Li, Xiangqun Zeng, Sheng-Ce Tao, S and Peng George Wang, Cheng Ma, Shukkoor Muhammed Kondengaden, Eugene Joeh, Zak Vilen, Timothy O'Leary, Mia L. Huang, Jeffrey C. Gildersleeve, John Faulkner, Xuehong Song, Lianchun Wang, James Hooper, Yuan Guo, Dejian Zhou, Zachary Klamer, Brian Haab, Abdul Rehman, Lei Li, Xiangqun Zeng, Sheng-Ce Tao, S

Published
2020

19. Factors associated with treatment response to CD19 CAR-T therapy among a large cohort of B cell acute lymphoblastic leukemia

Author

Zhang, Xian, primary, Yang, Junfang, additional, Li, Jingjing, additional, Li, Wenqian, additional, Song, Dan, additional, Lu, Xin-an, additional, Wu, Fei, additional, Li, Jianqiang, additional, Chen, Dandan, additional, Li, Xiangqun, additional, Xu, Zhongwei, additional, Liu, Shuqiang, additional, Li, Ziyu, additional, Ying, Kui, additional, and Lu, Peihua, additional

Published
2021
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23. Factors Predicting Long-Term Survival Following CD19 CAR T-Cell Therapy in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Author

Zhang, Xian, primary, Yang, Junfang, additional, Li, Wenqian, additional, Zhang, Gailing, additional, Su, Yunchao, additional, Shi, Yanze, additional, Song, Dan, additional, Zhang, Min, additional, He, Jiujiang, additional, Xu, Li, additional, Li, Jingjing, additional, Lu, Xinan, additional, Li, Jianqiang, additional, Li, Xiangqun, additional, Xu, Zhongwei, additional, Li, Ziyu, additional, and Lu, Peihua, additional

Published
2020
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24. Feasibility, and Efficacy of Donor-Derived cd19-Targeted Car t-Cell Therapy in Refractory/Relapsed(r/r)b-Cell Acute Lymphoblastic Leukemia (b-all) Patients

Author

Zhang, Xian, primary, Yang, Junfang, additional, Li, Wenqian, additional, Zhang, Gailing, additional, Su, Yunchao, additional, Shi, Yanze, additional, Song, Dan, additional, Zhang, Min, additional, He, Jiujiang, additional, Xu, Li, additional, Qiu, Liyuan, additional, Lu, Xin-An, additional, Wu, Fei, additional, Li, Jianqiang, additional, Chen, Dandan, additional, Li, Xiangqun, additional, Li, Ziyu, additional, Li, Jingjing, additional, and Lu, Peihua, additional

Published
2020
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31. Analysis of Factors Predicting Treatment Response of 254 Patients Who Received CD19-Targeted CAR-T Cell Therapy for Relapsed/Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Author

Zhang, Xian, primary, Yang, Junfang, primary, Shi, Yanze, primary, Song, Dan, primary, Li, Jingjing, primary, Lu, Xin-an, primary, Wu, Fei, primary, Li, Jianqiang, primary, Chen, Dandan, primary, Li, Xiangqun, primary, Xu, Zhongwei, primary, Liu, Shuqiang, primary, Li, Ziyu, primary, YIng, Kui, primary, Wang, Wenya, primary, and Lu, Peihua, primary

Published
2019
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33. Prognosis and long-term neurodevelopmental outcome in conservatively treated twin-to-twin transfusion syndrome

Author

Ochiai Masayuki, Tsukimori Kiyomi, Yumoto Yasuo, Otera Yuka, Fukushima Kotaro, Morokuma Seiichi, Li Xiangqun, Hara Toshiro, and Wake Norio

Subjects
fetus, TTTS, long-term outcome, Gynecology and obstetrics, RG1-991
Abstract

Abstract Background Amnioreduction remains a treatment option for pregnancies with twin-to-twin transfusion syndrome (TTTS) not meeting criteria for laser surgery or those in which it is not feasible. Amnioreduction is a relatively simple treatment which does not require sophisticated technical equipment. Previous reports of conservative management have indicated that major neurodevelopmental impairment occurs in 14.3-26% of survivors. The purpose of this study was to investigate long-term neurodevelopmental outcome in conservatively treated TTTS. Methods During the nine-year study period from January 1996 to December 2004, all pregnancies with TTTS who were admitted to our center were investigated. TTTS was diagnosed by using standard prenatal ultrasound criteria, and staged according to the criteria of Quintero et al. We reviewed gestational age at diagnosis, gestational age at delivery, the stage of TTTS at diagnosis, and diagnosis to delivery interval. Neonatal cranial ultrasound findings were reviewed and the neurodevelopmental outcomes were evaluated. Results Twenty-one pregnancies with TTTS were included. Thirteen pregnancies (62%) were treated with serial amnioreduction. The mean gestational age at delivery was 28 weeks (22 - 34 weeks). The perinatal mortality rate was 42.9%. Twenty survivors were followed up until at least 3 years of age. The mean age at follow-up was 6.3 years (3 - 12 years). Six children (30%) had neurodevelopmental impairment. Four children (20%) had major neurodevelopmental impairment and two children (10%) had minor neurodevelopmental impairment. Children with neurodevelopmental impairment were delivered before 29 weeks of gestation. Conclusions Our study showed a high rate of perinatal mortality and a high rate of major neurodevelopmental impairment in conservatively treated TTTS. The long-term outcomes for the survivors with TTTS were good when survivors were delivered after 29 weeks of gestation.

Published
2011
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35. Sliding Mode Control of Grid Chaotic Oscillation based on Immune Algorithm

Author

Liu Jianhua, Yang Longyue, and Li Xiangqun

Subjects
Numerical Analysis, Variable structure control, Computer science, Oscillation, Applied Mathematics, Chaotic, Mode (statistics), Terminal sliding mode, Grid, Sliding mode control, Computer Science Applications, Nonlinear Sciences::Chaotic Dynamics, Computational Theory and Mathematics, Control theory, Algorithm, Analysis
Abstract

The bifurcation and chaos phenomenon which exist in power grid are threats to the stable operation of power grid and the safety of people and equipment. In order to eliminate the chaos phenomena in power grid, a kind of non-singular terminal sliding mode (NTSM) variable structure control method based on immune algorithm is put forward. The second-order model of grid chaotic oscillation is built and to be controlled by non-singular terminal sliding mode va riable structure controller. Meanwhile, the immune algorithm is introduced to optimize the sliding mode controller parameters. By means of simulation, the effectiveness of this method in the grid chaos control is verified.

Published
2014

39. Changes in the epidemic of pulmonary tuberculosis in Shanghai from 1992 to 2016.

Author

Dong, Sijia, Shen, Xin, Xia, Zhen, Li, Xiangqun, Pan, Qichao, and Zhao, Qi

Subjects
TUBERCULOSIS, EPIDEMICS, DISEASE incidence, TRENDS
Abstract

Copyright of Tropical Medicine & International Health is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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40. Later emergence of acquired drug resistance and its effect on treatment outcome in patients treated with Standard Short-Course Chemotherapy for tuberculosis

Author

Gao, Jingtao, primary, Ma, Yan, additional, Du, Jian, additional, Zhu, Guofeng, additional, Tan, Shouyong, additional, Fu, Yanyong, additional, Ma, Liping, additional, Zhang, Lianying, additional, Liu, Feiying, additional, Hu, Daiyu, additional, Zhang, Yanling, additional, Li, Xiangqun, additional, Li, Liang, additional, and Li, Qi, additional

Published
2016
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41. OMNeT++ and Mixim-based protocol simulator for satellite network

Author

Li Xiangqun, Hu Xiaohui, Wang Lu, Xu Fanjiang, Chen Jing, and Liu Lixiang

Subjects
Protocol stack, Engineering, business.industry, Physics::Space Physics, Communications satellite, Wireless, Topology (electrical circuits), Satellite, business, User requirements document, Protocol (object-oriented programming), Computer network, Graphical user interface
Abstract

In this paper, we present a novel satellite network simulation platform (SNSP) based on OMNeT++ and MiXiM for researchers to develop better protocols for satellite networks. In this platform, multi-formatted satellite orbit data are permitted as input, and inter-satellite links (ISL) are created according to satellites position and specified connection rules. Correspondingly, the satellite network topology will be built dynamically. Two kinds of wireless channels that include microwave channels and laser channels are provided to simulate the signal transmission in space. A three layer fundamental satellite protocol stack is provided to utilize new satellite communication protocols as default. Meanwhile, the performance analysis of satellite communication protocol can be observed easily from the friendly graphical user interface. With modularized architecture, SNSP can be extended flexibly according to user requirements. In addition, an example is provided to illustrate how to develop protocol in our platform1,2

Published
2011

43. Total chemical synthesis of human T-cell leukemia virus type 1 (HTLV-1) protease via native chemical ligation: Reexamination of the functional effect of C-terminal truncation

Author

Li, Changqing, Li, Xiangqun, and Lu, Wuyuan

Subjects
Human T-lymphotropic virus 1, Kinetics, viruses, Aspartic Acid Endopeptidases, Humans, Protein Multimerization, Article, Catalysis, Protein Structure, Secondary, Protein Structure, Tertiary
Abstract

Human T-cell leukemia virus 1 (HTLV-1) protease, a member of the aspartic acid protease family, plays critical roles in the pathogenesis of the virus and is an attractive viral target for therapeutic intervention. HTLV-1 protease consists of 125 amino acid residues and functions as a homodimer stabilized in part by a four-stranded beta-sheet comprising the N- and C-termini. Compared with many other viral proteases such as HIV-1 protease, HTLV-1 protease is elongated by an extra 10 amino acid residue "tail" at the C-terminus. The structural and functional role of the extra C-terminal residues in the catalysis of HTLV-1 protease has been a subject of debate for years. Using the native chemical ligation technique pioneered by Kent and coworkers, we chemically synthesized a full-length HTLV protease and a C-terminally truncated form encompassing residues 1-116. Enzyme kinetic analysis using three different peptide substrates indicated that truncation of the C-terminal tail lowered the turnover number of the viral enzyme by a factor of 2 and its catalytic efficiency by roughly 10-fold. Our findings differ from the two extreme views that the C-terminal tail of HTLV-1 protease is either fully dispensable or totally required for enzyme dimerization and/or catalysis.

Published
2010

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