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Background: Insomnia is a common sleep disorder, which seriously affects people's quality of life and work ability. In China, auricular therapy and moxibustion therapy have a long history in treating insomnia. Clinical studies have shown that auricular point and moxibustion can effectively improve insomnia symptoms. At present, auricular point combined with moxibustion in the treatment of insomnia has been widely used in China, but its overall effectiveness and safety are still unclear. There’s a lack of systematic evaluation of auricular point combined with moxibustion in the treatment of insomnia. This paper aims to evaluate the efficacy and safety of auricular point combined with moxibustion in the treatment of insomnia. Methods: Retrieve randomized controlled trials of auricular point combined with moxibustion from PubMed, EMbase, Cochrane Library, Web of Science, China National Knowledge Infrastructure(CNKI), WanFang, the Chongqing VIP Chinese Science and Technology Periodical Database, and China biomedical literature database(CBM) from their establishment to August 2020. Search Baidu Scholar, Google Scholar, International Clinical Trials Registry Platform (ICTRP), and Chinese Clinical Trials Registry (ChiCTR) for unpublished grey literature. Two researchers independently applied RevMan 5.3 software for data extraction and risk assessment of bias. Results: This study evaluated the efficacy and safety of auricular point combined with moxibustion in the treatment of insomnia from Pittsburgh sleep quality index(PSQI), Rhone planck sleepiness scale(RPSSR), Traditional chinese medicine syndrome scores, Hamilton anxiety scale(HAMA), Hamilton Depression(HAMD), 5-hydroxytryptamine(5-HT), incidence of adverse reactions and other aspects. Conclusion: This study will provide theoretical support for the clinical application of auricular point combined with moxibustion in the treatment of insomnia.

Background Fire needle therapy is an ancient external treatment method of traditional Chinese medicine. This therapy is simple to operate and has fewer side effects. Gouty arthritis is common disease that is often characterized by high excruciating pain on joint. Evidence from clinical studies show that fire needle exert therapeutic effects on gout arthritis, but no evidence-based medicine is available. This study aimed to evaluate the efficacy and safety of fire acupuncture in the treatment of gout arthritis. Methods Randomized controlled trials (RCTs) of fire needle in the treatment of GA published until May，2020 will be searched in the English databases (PubMed, EMBASE, web of science, the Cochrane Library）and Chinese databases (China National Knowledge Infrastructure, the Chongqing VIP Chinese Science and Technology Periodical Database, Wanfang database, and China biomedical literature database). Additional search will be performed on Google academy and Baidu Academy. Data will be extracted from the studies by two reviewers working independently. Subsequently, quality assessment and a meta-analysis will be carried out for the studies using RevMan 5.3. Results The efficacy and safety of fire needle in the treatment of GA will be evaluated based on overall effective rate, VAS, BUA, CRP, joint swelling and pain score, adverse reaction rate, and other clinical outcomes. Conclusions The proposed systematic review and meta-analysis are expected to provide reliable evidence for the clinical benefits of fire-needle therapy in GA.