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Objective: The aim of the study was to decrease the transportation cost while reducing the nutrition loss of Urechis unicinctus. Methods: Chitosan was used for pretreatment of Urechis unicinctus, and the changes of the main nutritional and physiological indexes of the three groups i.e., control group, after waterless preservation group and recovered group, were measured. Results: The optimal concentration of chitosan was 3 g/L. After being pretreated by chitosan, the survival rate of Urechis unicinctus could reach 67% after 64 h of waterless preservation. The survival rate, muscle glycogen, water holding capacity of the experimental group were all significantly higher than those of the control group （P＜0.05）. Compared with those groups without recovered, the content of crude protein, lactic acid, crude fat, and water were all dramatically decreased after recovered no matter in control group or in experimental group （P＜0.01）. Conclusion: Chitosan can improve the survival rate and quality of Urechis unicinctus after waterless preservation. This research provides reference for the study on waterless preservation method of Urechis unicinctus, and has certain application research value.

Ginsenoside compound K (CK) is the major intestinal bacterial metabolite of ginsenosides that exhibits anticancer potential in various cancer cells both in vitro and in vivo. The anticancer types, mechanisms, and effects of CK in the past decade have been summarized in this review. Briefly, CK exerts anticancer effects via multiple molecular mechanisms, including the inhibition of proliferation, invasion, and migration, the induction of apoptosis and autophagy, and anti‐angiogenesis. Some signaling pathways play a significant role in related processes, such as PI3K/Akt/mTOR, JNK/MAPK pathway, and reactive oxygen species (ROS). Moreover, the effects of CK combined with nanocarriers for anticancer efficiency are discussed in this review. Furthermore, we aimed to review the research progress of CK against cancer in the past decade, which might provide theoretical support and effective reference for further research on the medicinal value of small molecules, such as CK. [ABSTRACT FROM AUTHOR]

A 2D membrane-based separation technique has been increasingly applied to solve the problem of fresh water shortage via ion rejection. However, these 2D membranes often suffer from a notorious swelling problem when immersed in solution, resulting in poor rejection for the monovalent metal ion. The design of the antiswelling 2D lamellar membranes has been proved to be a big challenge for highly efficient desalination. Here a kind of self-crosslinked MXene membrane is proposed for ion rejection with an obviously suppressed swelling property, which takes advantage of the hydroxyl terminal groups on the MXene nanosheets by forming Ti-O-Ti bonds between the neighboring nanosheets via the self-crosslinking reaction (-OH + -OH = -O- + H 2 O) through a facile thermal treatment. The permeation rates of the monovalent metal ions through the self-crosslinked MXene membrane are about two orders of magnitude lower than those through the pristine MXene membrane, which indicates the obviously improved performance of the ion exclusion by self-crosslinking between the MXene lamellae. Moreover, the excellent stability of the self-crosslinked MXene membrane during the 70 h long-term ion separation also demonstrates its promising antiswelling property. Such a facile and efficient self-crosslinking strategy gives the MXene membrane a good antiswelling property for metal ion rejection, which is also suitable for many other 2D materials with tunable surface functional groups during membrane assembly.