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2. Robotic Versus Open Kidney Transplantation from Deceased Donors: A Prospective Observational Study

Author

Campi, R., Pecoraro, A., Li Marzi, V., Tuccio, A., Giancane, S., Peris, A., Cirami, C.L., Breda, Alberto, Vignolini, G., Serni, S., and Universitat Autònoma de Barcelona

Subjects
Deceased donor, Complications, Urology, Transplant, Kidney, Renal function, Robotic
Abstract

Background: While robot-assisted kidney transplantation (RAKT) from living donors has been shown to achieve favourable outcomes, there is a lack of evidence on the safety and efficacy of RAKT as compared with the gold standard open kidney transplantation (OKT) in the setting of deceased donors, who represent the source of most grafts worldwide.& nbsp;Objective: To compare the intraoperative, perioperative, and midterm outcomes of RAKT versus OKT from donors after brain death (DBDs).& nbsp;Design, setting, and participants: Data from consecutive patients undergoing RAKT or OKT from DBDs at a single academic centre between October 2017 and December 2020 were prospectively collected.& nbsp;Intervention: RAKT or OKT.& nbsp;Outcome measurements and statistical analysis: The primary outcomes were intraoperative adverse events, postoperative surgical complications, delayed graft function (DGF), and midterm functional outcomes. A multivariable logistic regression analysis assessed the independent predictors of DGF, trifecta, and suboptimal graft function (estimated glomerular filtration rate [eGFR] < 45 ml/min/1.73 m2) at the last follow-up.& nbsp;Results and limitations: Overall, 138 patients were included (117 [84.7%] OKTs and 21 [15.3%] RAKTs). The yearly proportion of RAKT ranged between 10% and 18% during the study period. The OKT and RAKT cohorts were comparable regarding all graft-related characteristics, while they differed regarding a few donor-and recipient-related factors. The median second warm ischaemic time, ureterovesical anastomosis time, postoperative complication rate, and eGFR trajectories did not differ significantly between the groups. A higher proportion of patients undergoing OKT experienced DGF; yet, at a median follow-up of 31 mo (interquartile range 19- 44), there was no difference between the groups regarding the dialysis-free and overall survival. At the multivariable analysis, donor-and/or recipient-related factors, but not the surgical approach, were independent predictors of DGF, trifecta, and suboptimal graft function at the last follow-up. The study is limited by its non randomised nature and the small sample size.& nbsp;Conclusions: Our study provides preliminary evidence supporting the noninferiority of RAKT from DBDs as compared with the gold standard OKT in carefully selected recipients.& nbsp;Patient summary: Kidney transplantation using kidneys from deceased donors is still being performed with an open surgical approach in most transplant centres worldwide. In fact, no study has compared the outcomes of open and minimally invasive (robotic) kidney transplantation from deceased donors. In this study, we evaluated whether robotic kidney transplantation using grafts from deceased donors was not inferior to open kidney transplantation regarding the intraoperative, postoperative, and midterm functional outcomes. We found that, in experienced hands and provided that there was a time-efficient organisation of the transplantation pathway, robotic kidney transplantation from deceased donors was feasible and achieved noninferior outcomes as compared with open kidney transplantation.(C) 2022 The Author(s). Published by Elsevier B.V. on behalf of European Association of Urology.& nbsp

Published
2022

3. Robot-assisted kidney transplantation: our 5-year experience

Author

Pecoraro, A., primary, Stracci, D., additional, Gallo, M.L., additional, Mariotti, A., additional, Marzocco, A., additional, Livio, V., additional, Mazzola, L., additional, Dibilio, E., additional, Polverino, P., additional, Nicoletti, R., additional, Lo Re, M., additional, Conte, F.L., additional, Alberti, A., additional, Li Marzi, V., additional, Vignolini, G., additional, Sebastianelli, A., additional, Sessa, F., additional, Campi, R., additional, and Serni, S., additional

Published
2022
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4. A multicenter italian study: the coexistent overactive-underactive bladder (COUB) syndrome

Author

Mancini, V., primary, Martino, L., additional, d’Altilia, N., additional, Annese, P., additional, Illiano, E., additional, Costantini, E., additional, Serati, M., additional, Li Marzi, V., additional, Greco, P., additional, Gubbiotti, M., additional, Giannantoni, A., additional, Balzarro, M., additional, Rubilotta, E., additional, Busetto, G.M., additional, Bettocchi, C., additional, Cormio, L., additional, and Carrieri, G., additional

Published
2022
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6. Perioperative Outcomes of Open, Laparoscopic, and Robotic Partial Nephrectomy: A Prospective Multicenter Observational Study (The RECORd 2 Project)

Author

Bravi, C, Larcher, A, Capitanio, U, Mari, A, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Bove, P, Brunocilla, E, Da Pozzo, L, Di Maida, F, Fiori, C, Gontero, P, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Porpiglia, F, Schiavina, R, Schips, L, Simeone, C, Siracusano, S, Terrone, C, Trombetta, C, Volpe, A, Montorsi, F, Ficarra, V, Carini, M, Minervini, A, Bravi C. A., Larcher A., Capitanio U., Mari A., Antonelli A., Artibani W., Barale M., Bertini R., Bove P., Brunocilla E., Da Pozzo L., Di Maida F., Fiori C., Gontero P., Li Marzi V., Longo N., Mirone V., Montanari E., Porpiglia F., Schiavina R., Schips L., Simeone C., Siracusano S., Terrone C., Trombetta C., Volpe A., Montorsi F., Ficarra V., Carini M., Minervini A., Bravi, C, Larcher, A, Capitanio, U, Mari, A, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Bove, P, Brunocilla, E, Da Pozzo, L, Di Maida, F, Fiori, C, Gontero, P, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Porpiglia, F, Schiavina, R, Schips, L, Simeone, C, Siracusano, S, Terrone, C, Trombetta, C, Volpe, A, Montorsi, F, Ficarra, V, Carini, M, Minervini, A, Bravi C. A., Larcher A., Capitanio U., Mari A., Antonelli A., Artibani W., Barale M., Bertini R., Bove P., Brunocilla E., Da Pozzo L., Di Maida F., Fiori C., Gontero P., Li Marzi V., Longo N., Mirone V., Montanari E., Porpiglia F., Schiavina R., Schips L., Simeone C., Siracusano S., Terrone C., Trombetta C., Volpe A., Montorsi F., Ficarra V., Carini M., and Minervini A.

Abstract

Background: Partial nephrectomy (PN) has a non-negligible perioperative morbidity. Comparative evidence of the available surgical techniques is limited. Objective: To compare the perioperative outcomes of open, laparoscopic, and robotic PN. Methods: Data of 2331 patients treated with PN for cT1 renal tumors were extracted from the RECORd2 database, a prospective multicenter project. Multivariable regression models assessed the relationship between surgical technique and surgical margins, warm ischemia time, postoperative complications, and acute kidney injury (AKI). The probability of achieving a modified trifecta (negative margins, warm ischemia time <25 min, and no Clavien–Dindo ≥2 complications) was examined for each surgical approach. Results: Minimally invasive techniques had lower rate of Clavien–Dindo ≥2 complications than that of open surgery (odds ratio [OR] for robotic surgery: 0.27; 95% confidence interval [95% CI]: 0.15–0.47, p < 0.0001; OR for laparoscopy: 0.52; 95% CI: 0.34–0.78; p = 0.002). The probability of receiving ischemia was highest for robotic PN (p < 0.001). Among on-clamp PN, laparoscopy had longer ischemia than open (estimate: 1.09; 95% CI: –0.00 to 2.18; p = 0.050) and robotic (estimate: 1.36; 95% CI: 0.31–2.40; p = 0.011) surgery. When compared with open PN, the risk of AKI was roughly halved for patients treated by robotic and laparoscopic surgery (both p < 0.0001). Positive margins rate did not differ between the groups (all p ≥ 0.1). The likelihood to achieve a modified trifecta was not affected by surgical technique in the overall population (all p ≥ 0.075). In Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score < 10 lesions, robotic surgery had higher probability of achieving a modified trifecta than open PN (OR: 1.66; 95% CI: 1.09–2.53; p = 0.018) and laparoscopy (OR: 1.34; 95% CI: 0.94–1.90; p = 0.11). Conclusions: In PADUA < 10 renal tumors, robotic PN allows for higher rates of trifecta than

Published
2021

7. Perioperative Outcomes of Open, Laparoscopic, and Robotic Partial Nephrectomy: A Prospective Multicenter Observational Study (The RECORd 2 Project)

Author

Bravi, C. A., Larcher, A., Capitanio, U., Mari, A., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Bove, P., Brunocilla, E., Da Pozzo, L., Di Maida, F., Fiori, C., Gontero, P., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Porpiglia, F., Schiavina, R., Schips, L., Simeone, C., Siracusano, S., Terrone, C., Trombetta, C., Volpe, A., Montorsi, F., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Borghesi, M., Celia, A., Cindolo, L., Costantini, E., Daja, J., Falsaperla, M., Furlan, M., Morgia, G., Porreca, A., Roscigno, M., Selli, C., Simonato, A., Tellini, R., Vespasiani, G., Villari, D., Bravi, C, Larcher, A, Capitanio, U, Mari, A, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Bove, P, Brunocilla, E, Da Pozzo, L, Di Maida, F, Fiori, C, Gontero, P, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Porpiglia, F, Schiavina, R, Schips, L, Simeone, C, Siracusano, S, Terrone, C, Trombetta, C, Volpe, A, Montorsi, F, Ficarra, V, Carini, M, Minervini, A, Bravi, C. A., Larcher, A., Capitanio, U., Mari, A., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Bove, P., Brunocilla, E., Da Pozzo, L., Di Maida, F., Fiori, C., Gontero, P., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Porpiglia, F., Schiavina, R., Schips, L., Simeone, C., Siracusano, S., Terrone, C., Trombetta, C., Volpe, A., Montorsi, F., Ficarra, V., Carini, M., Minervini, A., and Bravi CA, Larcher A, Capitanio U, Mari A, Antonelli A, Artibani W, Barale M, Bertini R, Bove P, Brunocilla E, Da Pozzo L, Di Maida F, Fiori C, Gontero P, Li Marzi V, Longo N, Mirone V, Montanari E, Porpiglia F, Schiavina R, Schips L, Simeone C, Siracusano S, Terrone C, Trombetta C, Volpe A, Montorsi F, Ficarra V, Carini M, Minervini A

Subjects
Male, medicine.medical_specialty, Urology, medicine.medical_treatment, 030232 urology & nephrology, Acute kidney injury, Laparoscopy, Partial nephrectomy, Perioperative outcomes, Renal cell carcinoma, Robotic surgery, Trifecta, Nephrectomy, 03 medical and health sciences, 0302 clinical medicine, Robotic Surgical Procedures, Ischemia, Medicine, Humans, Minimally Invasive Surgical Procedures, Prospective Studies, Perioperative Period, Aged, medicine.diagnostic_test, business.industry, renal carcinoma, Odds ratio, Perioperative, Middle Aged, medicine.disease, Confidence interval, Kidney Neoplasms, Surgery, Settore MED/24, 030220 oncology & carcinogenesis, Female, Acute kidney injury, Laparoscopy, Partial nephrectomy, Perioperative outcomes, Renal cell carcinoma, Robotic surgery, Trifecta, business, Perioperative outcome
Abstract

Background: Partial nephrectomy (PN) has a non-negligible perioperative morbidity. Comparative evidence of the available surgical techniques is limited. Objective: To compare the perioperative outcomes of open, laparoscopic, and robotic PN. Methods: Data of 2331 patients treated with PN for cT1 renal tumors were extracted from the RECORd2 database, a prospective multicenter project. Multivariable regression models assessed the relationship between surgical technique and surgical margins, warm ischemia time, postoperative complications, and acute kidney injury (AKI). The probability of achieving a modified trifecta (negative margins, warm ischemia time

Published
2021

8. Gender disparities in kidney surgery: A real-life snapshot for a large prospective, multicenter observational study (the RECORd2 Project)

Author

Mari, A., primary, Antonelli, A., additional, Tafuri, A., additional, Tellini, R., additional, Brunocilla, E., additional, Capitanio, U., additional, Di Maida, F., additional, Gontero, P., additional, Grosso, A.A., additional, Nardoni, S., additional, Li Marzi, V., additional, Longo, N., additional, Montorsi, F., additional, Porpiglia, F., additional, Porreca, A., additional, Rocco, B., additional, Simeone, C., additional, Schiavina, R., additional, Schips, L., additional, Siracusano, S., additional, Terrone, C., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2022
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9. Bladder-neck sparing robot assisted radical prostatectomy: Step-by step procedure

Author

Sessa, F., primary, Rivetti, A., additional, Campi, R., additional, Nicoletti, R., additional, Polverino, P., additional, Verdelli, L., additional, Pecoraro, A., additional, Barzaghi, P., additional, Morselli, S., additional, Gacci, M., additional, Giancane, S., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Gallo, M.L., additional, Vignolini, G., additional, and Serni, S., additional

Published
2022
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10. Perioperative and functional outcomes after kidney transplantation from uncontrolled donors after circulatory death vs. expanded-criteria donors after brain death vs. standard-criteria donors: Toward an evidence-based refinement of allocation strategies

Author

Campi, R., primary, Pecoraro, A., additional, Sessa, F., additional, Barzaghi, P., additional, Rivetti, A., additional, Nicoletti, R., additional, Gallo, M.L., additional, Corti, F., additional, Morselli, S., additional, Spatafora, P., additional, Gacci, M., additional, Giancane, S., additional, Sebastianelli, A., additional, Cirami, L., additional, Peris, A., additional, Vignolini, G., additional, Serni, S., additional, and Li Marzi, V., additional

Published
2022
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11. Robotic versus open kidney transplantation from deceased donors: The first prospective observational study

Author

Campi, R., primary, Pecoraro, A., additional, Li Marzi, V., additional, Tuccio, A., additional, Barzaghi, P., additional, Corti, F., additional, Rivetti, A., additional, Nicoletti, R., additional, Gacci, M., additional, Morselli, S., additional, Sebastianelli, A., additional, Sessa, F., additional, Spatafora, P., additional, Giancane, S., additional, Peris, A., additional, Cirami, C.L., additional, Breda, A., additional, Vignolini, G., additional, and Serni, S., additional

Published
2022
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12. Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project)

Author

Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, Villari, D, Mari A., Campi R., Schiavina R., Amparore D., Antonelli A., Artibani W., Barale M., Bertini R., Borghesi M., Bove P., Brunocilla E., Capitanio U., Da Pozzo L., Daja J., Gontero P., Larcher A., Li Marzi V., Longo N., Mirone V., Montanari E., Pisano F., Porpiglia F., Simeone C., Siracusano S., Tellini R., Trombetta C., Volpe A., Ficarra V., Carini M., Minervini A., Altieri V., Berardinelli F., Celia A., Costantini E., Di Maida F., Falsaperla M., Fiori C., Furlan M., Marson F., Montorsi F., Morgia G., Porreca A., Roscigno M., Schips L., Selli C., Simonato A., Terrone C., Vespasiani G., Villari D., Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, Villari, D, Mari A., Campi R., Schiavina R., Amparore D., Antonelli A., Artibani W., Barale M., Bertini R., Borghesi M., Bove P., Brunocilla E., Capitanio U., Da Pozzo L., Daja J., Gontero P., Larcher A., Li Marzi V., Longo N., Mirone V., Montanari E., Pisano F., Porpiglia F., Simeone C., Siracusano S., Tellini R., Trombetta C., Volpe A., Ficarra V., Carini M., Minervini A., Altieri V., Berardinelli F., Celia A., Costantini E., Di Maida F., Falsaperla M., Fiori C., Furlan M., Marson F., Montorsi F., Morgia G., Porreca A., Roscigno M., Schips L., Selli C., Simonato A., Terrone C., Vespasiani G., and Villari D.

Abstract

Objective: To identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN). Patients and Methods: We prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. A nomogram was created from the multivariable model. Internal validation processes were performed using bootstrapping with 1000 repetitions. Results: Overall, 2584 patients who underwent PN were evaluated for the final analyses. The median (interquartile [IQR]) American Society of Anesthesiologists (ASA) score was 2 (2–3). In all, 72.4% of patients had clinical T1a (cT1a) stage tumours. The median (IQR) Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score was 7 (6–8). Overall, 34.3%, 27.7%, 38% of patients underwent open PN (OPN), laparoscopic PN (LPN), and robot-assisted PN (RAPN). Overall and major postoperative surgical complications were recorded in 10.2% and 2.5% of patients, respectively. At multivariable analysis, age, ASA score, cT2 vs cT1a stage, PADUA score, preoperative anaemia, OPN and LPN vs RAPN, were significant predictive factors of postoperative surgical complications. We used these variables to construct a nomogram for predicting the risk of postoperative surgical complications. At decision curve analysis, the nomogram led to superior outcomes for any decision associated with a threshold probability of >5%. Conclusion: Several clinical predictors have been associated with postoperative surgical complications after PN. We used this information to develop and internally validate a nomogram to predict such risk.

Published
2019

13. Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project)

Author

Mari, A., Campi, R., Schiavina, R., Amparore, D., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Borghesi, M., Bove, P., Brunocilla, E., Capitanio, U., Da Pozzo, L., Daja, J., Gontero, P., Larcher, A., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Pisano, F., Porpiglia, F., Simeone, C., Siracusano, S., Tellini, R., Trombetta, C., Volpe, A., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Celia, A., Costantini, E., Di Maida, F., Falsaperla, M., Fiori, C., Furlan, M., Marson, F., Montorsi, F., Morgia, G., Porreca, A., Roscigno, M., Schips, L., Selli, C., Simonato, A., Terrone, C., Vespasiani, G., Villari, D., Mari A, Campi R, Schiavina R, Amparore D, Antonelli A, Artibani W, Barale M, Bertini R, Borghesi M, Bove P, Brunocilla E, Capitanio U, Da Pozzo L, Daja J, Gontero P, Larcher A, Li Marzi V, Longo N, Mirone V, Montanari E, Pisano F, Porpiglia F, Simeone C, Siracusano S, Tellini R, Trombetta C, Volpe A, Ficarra V, Carini M, Minervini A, Mari, Andrea, Campi, Riccardo, Schiavina, Riccardo, Amparore, Daniele, Antonelli, Alessandro, Artibani, Walter, Barale, Maurizio, Bertini, Roberto, Borghesi, Marco, Bove, Pierluigi, Brunocilla, Eugenio, Capitanio, Umberto, Da Pozzo, Luigi, Daja, Julian, Gontero, Paolo, Larcher, Alessandro, Li Marzi, Vincenzo, Longo, Nicola, Mirone, Vincenzo, Montanari, Emanuele, Pisano, Francesca, Porpiglia, Francesco, Simeone, Claudio, Siracusano, Salvatore, Tellini, Riccardo, Trombetta, Carlo, Volpe, Alessandro, Ficarra, Vincenzo, Carini, Marco, Minervini, Andrea, Mari, A., Campi, R., Schiavina, R., Amparore, D., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Borghesi, M., Bove, P., Brunocilla, E., Capitanio, U., Da Pozzo, L., Daja, J., Gontero, P., Larcher, A., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Pisano, F., Porpiglia, F., Simeone, C., Siracusano, S., Tellini, R., Trombetta, C., Volpe, A., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Celia, A., Costantini, E., Di Maida, F., Falsaperla, M., Fiori, C., Furlan, M., Marson, F., Montorsi, F., Morgia, G., Porreca, A., Roscigno, M., Schips, L., Selli, C., Simonato, A., Terrone, C., Vespasiani, G., Villari, D., Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, and Villari, D

Subjects
partial nephrectomy, complications, Male, medicine.medical_specialty, renal cell carcinoma, nephron-sparing surgery, nomogram, robot-assisted partial nephrectomy, medicine.medical_treatment, Urology, 030232 urology & nephrology, complication, Logistic regression, Nephrectomy, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Interquartile range, Renal cell carcinoma, complications, nephron-sparing surgery, nomogram, partial nephrectomy, renal cell carcinoma, robot-assisted partial nephrectomy, Medicine, Humans, In patient, Prospective Studies, Stage (cooking), Aged, business.industry, Nomogram, postoperative surgical complications, partial nephrectomy, RECORd 2 project, Kidney Neoplasm, Nomogram, Middle Aged, medicine.disease, Kidney Neoplasms, Surgery, Editorial Commentary, Nomograms, Settore MED/24, 030220 oncology & carcinogenesis, partial nephrectomy, complications, Observational study, Female, Postoperative Complication, business, Human
Abstract

Objective To identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN). Patients and methods We prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. A nomogram was created from the multivariable model. Internal validation processes were performed using bootstrapping with 1000 repetitions. Results Overall, 2584 patients who underwent PN were evaluated for the final analyses. The median (interquartile [IQR]) American Society of Anesthesiologists (ASA) score was 2 (2-3). In all, 72.4% of patients had clinical T1a (cT1a) stage tumours. The median (IQR) Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score was 7 (6-8). Overall, 34.3%, 27.7%, 38% of patients underwent open PN (OPN), laparoscopic PN (LPN), and robot-assisted PN (RAPN). Overall and major postoperative surgical complications were recorded in 10.2% and 2.5% of patients, respectively. At multivariable analysis, age, ASA score, cT2 vs cT1a stage, PADUA score, preoperative anaemia, OPN and LPN vs RAPN, were significant predictive factors of postoperative surgical complications. We used these variables to construct a nomogram for predicting the risk of postoperative surgical complications. At decision curve analysis, the nomogram led to superior outcomes for any decision associated with a threshold probability of >5%. Conclusion Several clinical predictors have been associated with postoperative surgical complications after PN. We used this information to develop and internally validate a nomogram to predict such risk.

Published
2019

14. Partial versus radical nephrectomy for the treatment of T1 renal tumors: a large contemporary matched-cohort study (RECORd2 project)

Author

Tellini, R., primary, Mari, A., additional, Amparore, D., additional, Antonelli, A., additional, Allasia, M., additional, Bove, P., additional, Brunocilla, E., additional, Capitanio, U., additional, Di Maida, F., additional, Gontero, P., additional, Longo, N., additional, Montorsi, F., additional, Gallioli, A., additional, Grosso, A.A., additional, Porpiglia, F., additional, Porreca, A., additional, Rocco, B., additional, Schiavina, R., additional, Li Marzi, V., additional, Trombetta, C., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2021
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15. Assessing the intra- and postoperative morbidity of kidney cancer surgery for organ-confined (cT1-T2N0M0) renal masses according to the eau quality criteria for standardized reporting: a prospective single-centre study

Author

Serni, S., primary, Pecoraro, A., additional, Rivetti, A., additional, Sessa, F., additional, Barzaghi, P., additional, Corti, F., additional, Caneschi, C., additional, Santalmasi, C., additional, Paganelli, D., additional, Basilico, V., additional, Morselli, S., additional, Nicoletti, R., additional, Giancane, S., additional, Spatafora, P., additional, Gacci, M., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Vignolini, G., additional, and Campi, R., additional

Published
2021
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16. Perioperative and mid-term oncological and functional outcomes after partial nephrectomy for entirely endophytic renal tumors: a prospective multicenter observational study (the RECORD 2 project)

Author

Di Maida, F., primary, Mari, A., additional, Antonelli, A., additional, Barale, M., additional, Bove, P., additional, Brunocilla, E., additional, Lambertini, L., additional, Capitanio, U., additional, Fiori, C., additional, Gallioli, A., additional, Grosso, A.A., additional, Gontero, P., additional, Longo, N., additional, Montorsi, F., additional, Porpiglia, F., additional, Porreca, A., additional, Rocco, B., additional, Schiavina, R., additional, Li Marzi, V., additional, Tellini, R., additional, Trombetta, C., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2021
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17. Rate and predictors of benign pathology after surgery for localized (cT1N0M0) renal masses at a high-volume academic centre: implications for selection of renal biopsy candidates

Author

Pecoraro, A., primary, Rivetti, A., additional, Sessa, F., additional, Barzaghi, P., additional, Corti, F., additional, Morselli, S., additional, Ferretti, R., additional, Garcia, J.M., additional, Freso, A., additional, Berni, A., additional, Nicoletti, R., additional, Giancane, S., additional, Gacci, M., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Vignolini, G., additional, Serni, S., additional, and Campi, R., additional

Published
2021
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18. Significant renal function decline after partial nephrectomy: martini’s nomogram validation in RECORD 2 project cohort

Author

Minervini, A., primary, Antonelli, A., additional, Mari, A., additional, Tafuri, A., additional, Tellini, R., additional, Brunocilla, E., additional, Capitanio, U., additional, Di Maida, F., additional, Diminutto, A., additional, Gontero, P., additional, Grosso, A.A., additional, Li Marzi, V., additional, Longo, N., additional, Montorsi, F., additional, Porpiglia, F., additional, Porreca, A., additional, Rocco, B., additional, Simeone, C., additional, Schiavina, R., additional, Schips, L., additional, Siracusano, S., additional, Terrone, C., additional, Ficarra, V., additional, and Carini, M., additional

Published
2021
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19. Urethral bulking in the treatment of stress and mixed female urinary incontinence: results of a multicenter study on a large cohort of patients

Author

Geretto, P., primary, Ammirati, E., additional, Squintone, L., additional, Manassero, A., additional, Chierchia, S., additional, Del Popolo, G., additional, Pistolesi, D., additional, Risi, O., additional, Costantini, E., additional, Giannantoni, A., additional, Mancini, V., additional, Li Marzi, V., additional, Agrò, E. Finazzi, additional, Pastorello, M., additional, Musco, S., additional, Gontero, P., additional, and Giammò, A., additional

Published
2021
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20. Is robotic kidney transplantation non-inferior to open kidney transplantation in the setting of deceased donors? A single-centre preliminary experience

Author

Campi, R., primary, Pecoraro, A., additional, Sessa, F., additional, Barzaghi, P., additional, Corti, F., additional, Morselli, S., additional, Rivetti, A., additional, Nicoletti, R., additional, Giancane, S., additional, Spatafora, P., additional, Tuccio, A., additional, Gacci, M., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Vignolini, G., additional, and Serni, S., additional

Published
2021
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22. Four-year experience with robotic kidney transplantation from deceased donors: Overcoming logistical and technical challenges to broaden the indications of robotic kidney transplantation

Author

Campi, R., primary, Vignolini, G., additional, Pecoraro, A., additional, Morselli, S., additional, Nicoletti, R., additional, Rivetti, A., additional, Berni, A., additional, Paganelli, D., additional, Sessa, F., additional, Greco, I., additional, Corti, F., additional, Mormile, N., additional, Barzaghi, P., additional, Gianassi, J., additional, Cutruzzullà, R., additional, Spatafora, P., additional, Sebastianelli, A., additional, Giancane, S., additional, Li Marzi, V., additional, Gacci, M., additional, Cirami, C., additional, and Serni, S., additional

Published
2021
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23. Perioperative and mid-term oncological and functional outcomes after partial nephrectomy for entirely endophytic renal tumors: A prospective multicenter observational study (the RECORD2 Project)

Author

Mari, A., primary, Di Maida, F., additional, Antonelli, A., additional, Barale, M., additional, Bove, P., additional, Brunocilla, E., additional, Campi, R., additional, Capitanio, U., additional, Fiori, C., additional, Gallioli, A., additional, Grosso, A.A., additional, Gontero, P., additional, Longo, N., additional, Montorsi, F., additional, Porpiglia, F., additional, Porreca, A., additional, Rocco, B., additional, Schiavina, R., additional, Li Marzi, V., additional, Tellini, R., additional, Trombetta, C., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2021
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25. Robot-assisted laparoscopic living donor nephrectomy: The university of Florence technique

Author

Campi, R., primary, Pecoraro, A., additional, Sessa, F., additional, Morselli, S., additional, Gemma, L., additional, Greco, I., additional, Barzaghi, P., additional, Grosso, A.A., additional, Corti, F., additional, Mormile, N., additional, Spatafora, P., additional, Caroassai, S., additional, Berni, A., additional, Caneschi, C., additional, Gacci, M., additional, Giancane, S., additional, Sebastianelli, A., additional, Li Marzi, V., additional, Vignolini, G., additional, and Serni, S., additional

Published
2021
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26. Extensive impact of COVID-19 pandemic on pelvic floor dysfunctions care: A nationwide interdisciplinary survey

Author

Sacco, Emilio, Gandi, Carlo, Li Marzi, V., Lamberti, G., Serati, M., Agro', E. F., Soligo, M., Sacco E. (ORCID:0000-0003-4640-8354), Gandi C., Sacco, Emilio, Gandi, Carlo, Li Marzi, V., Lamberti, G., Serati, M., Agro', E. F., Soligo, M., Sacco E. (ORCID:0000-0003-4640-8354), and Gandi C.

Abstract

Aims: To investigate the impact of COVID-19 pandemic on health-care provision to patients suffering from pelvic floor dysfunctions in Italy. Methods: A retrospective web-based interdisciplinary survey was mailed by the Italian Society of Urodynamics to members involved in pelvic floor dysfunctions management from June 22, 2020 to July 17, 2020. The 84-item questionnaire investigated the period March–June 2020 (first epidemic wave) and showed high content validity. The primary outcome was the mean rate of cancellation for health-care services. Secondary outcomes included estimation of the accumulated surgeries backload until return to baseline activity and of the recovery pattern, using linear regression and scenario-based forecasting. Results: A total of 85 participants provided complete responses. Respondents were mostly urologists (47%), followed by gynecologists (29.5%) and physiatrists (17.6%). On average, 78.4% of outpatient services and 82.7% of functional surgeries were canceled, without significant differences by geographical distribution. An impact on patients' quality of life was anticipated by most of the respondents (87%) and 48.2% also reported potentially serious health risks for patients. Thirty-three percent of the respondents reported the use of telemedicine. If the nation-wide surgical activity increases by 20% postpandemic, it would take 37 months to clear the backlog of functional surgeries. We acknowledge the inherent limitations of the survey methodology and retrospective design. Conclusions: Access to care for patients suffering from pelvic floor dysfunctions has been dramatically affected by the COVID-19 outbreak. The indirect effects of this unprecedented disruption on pelvic floor dysfunctions care may last for several months.

Published
2021

34. Perioperative and functional outcomes after kidney transplantation from uncontrolled donors after circulatory death (UDCD) vs extended criteria donors after brain death (eDBD): A single-centre experience

Author

Li Marzi, V., primary, Campi, R., additional, Pecoraro, A., additional, Greco, I., additional, Gemma, L., additional, Sessa, F., additional, Giancane, S., additional, Tuccio, A., additional, Gacci, M., additional, Sebastianelli, A., additional, Lazzeri, C., additional, Vignolini, G., additional, Cirami, C.L., additional, Migliaccio, M.L., additional, Peris, A., additional, and Serni, S., additional

Published
2020
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35. Robotic living donor nephrectomy: our 10-year experience

Author

Serni, S., primary, Campi, R., additional, Greco, I., additional, Pecoraro, A., additional, Sessa, F., additional, Manetti, C., additional, Dattolo, F., additional, Mascherini, J., additional, Gemma, L., additional, Grosso, A., additional, Barzaghi, P., additional, Corti, F., additional, Mormile, N., additional, Grisanti, S.Caroassai, additional, Giancane, S., additional, Tuccio, A., additional, Gacci, M., additional, Li Marzi, V., additional, Sebastianelli, A., additional, and Vignolini, G., additional

Published
2020
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36. Feasibility and safety of a kidney transplantation program from donors after brain death during the COVID-19 pandemic: insights from an Italian academic centre

Author

Li Marzi, V., primary, Campi, R., additional, Pecoraro, A., additional, Greco, I., additional, Caroti, L., additional, Cirami, C.L., additional, Giancane, S., additional, Lazzeri, C., additional, Tuccio, A., additional, Vignolini, G., additional, Migliaccio, M.L., additional, Peris, A., additional, and Serni, S., additional

Published
2020
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37. Robotic radical cystectomy with open-assisted hybrid orthotopic ileal neobladder: a prospective single-centre study (IDEAL phase 2a)

Author

Vignolini, G., primary, Campi, R., additional, Sessa, F., additional, Gemma, L., additional, Greco, I., additional, Pecoraro, A., additional, Barzaghi, P., additional, Corti, F., additional, Giancane, S., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Gacci, M., additional, and Serni, S., additional

Published
2020
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38. Perioperative and functional outcomes after robotic vs open kidney transplantation using grafts from donors after brain death: preliminary experience

Author

Greco, I., primary, Pecoraro, A., additional, Gemma, L., additional, Sessa, F., additional, Grosso, A., additional, Barzaghi, P., additional, Corti, F., additional, Mormile, N., additional, Grisanti, S.Caroassai, additional, Giancane, S., additional, Tuccio, A., additional, Gacci, M., additional, Li Marzi, V., additional, Sebastianelli, A., additional, Vignolini, G., additional, Serni, S., additional, and Campi, R., additional

Published
2020
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39. What are the predictors of oncocytoma histology at pathological analysis after partial nephrectomy for small renal masses? insights from a large prospective multicentre study (record 2 project)

Author

Tellini, R., primary, Campi, R., additional, Mari, A., additional, Amparore, D., additional, Antonelli, A., additional, Brunocilla, E., additional, Capitanio, U., additional, Gontero, P., additional, Longo, N., additional, Montanari, E., additional, Li Marzi, V., additional, Roscigno, M., additional, Larcher, A., additional, Montorsi, F., additional, Fiori, C., additional, Porpiglia, F., additional, Simeone, C., additional, Siracusano, S., additional, Trombetta, C., additional, Artibani, W., additional, Volpe, A., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2020
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40. Robotic kidney transplantation program from living and deceased donors: our 3-year experience

Author

Serni, S., primary, Campi, R., additional, Greco, I., additional, Pecoraro, A., additional, Sessa, F., additional, Gemma, L., additional, Grosso, A.A., additional, Martiriggiano, M., additional, Firenzuoli, N., additional, Barzaghi, P., additional, Corti, F., additional, Mormile, N., additional, Giancane, S., additional, Tuccio, A., additional, Sebastianelli, A., additional, Mauro, G., additional, Li Marzi, V., additional, and Vignolini, G., additional

Published
2020
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41. What are the predictors of oncocytoma histology at pathological analysis after partial nephrectomy for small renal masses? Insights from a large prospective multicentre study (RECORd2 project)

Author

Tellini, R., primary, Campi, R., additional, Mari, A., additional, Amparore, D., additional, Antonelli, A., additional, Brunocilla, E., additional, Capitanio, U., additional, Gontero, P., additional, Mirone, V., additional, Montanari, E., additional, Li Marzi, V., additional, Roscigno, M., additional, Montorsi, F., additional, Porpiglia, F., additional, Simeone, C., additional, Trombetta, C., additional, Artibani, W., additional, Volpe, A., additional, Ficarra, V., additional, Carini, M., additional, and Minervini, A., additional

Published
2020
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43. The healthier the patient, the longer the ischemia: Surgical implications for partial nephrectomy in the RECORd2 project

Author

Bravi, C.A., primary, Larcher, A., additional, Capitanio, U., additional, Montorsi, F., additional, Bertini, R., additional, Antonelli, A., additional, Siracusano, S., additional, Barale, M., additional, Gontero, P., additional, Bove, P., additional, Brunocilla, E., additional, Schiavina, R., additional, Da Pozzo, L., additional, Longo, N., additional, Montanari, E., additional, Porpiglia, F., additional, Simeone, C., additional, Volpe, A., additional, Ficarra, V., additional, Li Marzi, V., additional, Di Maida, F., additional, Mari, A., additional, Carini, M., additional, and Minervini, A., additional

Published
2020
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44. The role of external beam radiation therapy for post prostatectomy stress urinary incontinence in transobturator male sling outcomes. A multicentric experience

Author

Morselli, S., primary, Li Marzi, V., additional, Baldesi, R., additional, Fantechi, R., additional, Gemma, L., additional, Liaci, A., additional, Di Camillo, M., additional, Traversi, C., additional, Tosto, A., additional, Francesca, F., additional, Gerolamo, M., additional, and Serni, S., additional

Published
2020
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49. A1101 - Perioperative and functional outcomes after kidney transplantation from uncontrolled donors after circulatory death vs. expanded-criteria donors after brain death vs. standard-criteria donors: Toward an evidence-based refinement of allocation strategies

Author

Campi, R., Pecoraro, A., Sessa, F., Barzaghi, P., Rivetti, A., Nicoletti, R., Gallo, M.L., Corti, F., Morselli, S., Spatafora, P., Gacci, M., Giancane, S., Sebastianelli, A., Cirami, L., Peris, A., Vignolini, G., Serni, S., and Li Marzi, V.

Published
2022
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