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5 results on '"Lia Halasz"'

1. Treatment of ocular tumors through a novel applicator on a conventional proton pencil beam scanning beamline

Author

Rajesh Regmi, Dominic Maes, Alexander Nevitt, Allison Toltz, Erick Leuro, Jonathan Chen, Lia Halasz, Ramesh Rengan, Charles Bloch, and Jatinder Saini

Subjects
Medicine, Science
Abstract

Abstract Treatment of ocular tumors on dedicated scattering-based proton therapy systems is standard afforded due to sharp lateral and distal penumbras. However, most newer proton therapy centers provide pencil beam scanning treatments. In this paper, we present a pencil beam scanning (PBS)-based ocular treatment solution. The design, commissioning, and validation of an applicator mount for a conventional PBS snout to allow for ocular treatments are given. In contrast to scattering techniques, PBS-based ocular therapy allows for inverse planning, providing planners with additional flexibility to shape the radiation field, potentially sparing healthy tissues. PBS enables the use of commercial Monte Carlo algorithms resulting in accurate dose calculations in the presence of heterogeneities and fiducials. The validation consisted of small field dosimetry measurements of point doses, depth doses, and lateral profiles relevant to ocular therapy. A comparison of beam properties achieved through the applicator against published literature is presented. We successfully showed the feasibility of PBS-based ocular treatments.

Published
2022
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2. Brain Tumor Segmentation (BraTS) Challenge 2024: Meningioma Radiotherapy Planning Automated Segmentation.

Author

Dominic LaBella, Katherine Schumacher, Michael Mix, Kevin Leu, Shan McBurney-Lin, Pierre Nedelec, Javier E. Villanueva-Meyer, Jonathan Shapey, Tom Vercauteren, Kazumi Chia, Omar Al-Salihi, Justin Leu, Lia Halasz, Yury Velichko, Chunhao Wang, John Kirkpatrick, Scott Floyd, Zachary J. Reitman, Trey Mullikin, Ulas Bagci, Sean Sachdev, Jona A. Hattangadi-Gluth, Tyler M. Seibert, Nikdokht Farid, Connor Puett, Matthew W. Pease, Kevin Shiue, Syed Muhammad Anwar, Shahriar Faghani, Muhammad Ammar Haider, Pranav I. Warman, Jake Albrecht, András Jakab, Mana Moassefi, Verena Chung, Alejandro Aristizabal, Alexandros Karargyris, Hasan Kassem, Sarthak Pati, Micah J. Sheller, Christina Huang, Aaron Coley, Siddharth Ghanta, Alex Schneider, Conrad Sharp, Rachit Saluja, Florian Kofler, Philipp Lohmann, Philipp Vollmuth, Louis Gagnon, Maruf Adewole, Hongwei Bran Li, Anahita Fathi Kazerooni, Nourel Hoda Tahon, Udunna Anazodo, Ahmed W. Moawad, Bjoern H. Menze, Marius George Linguraru, Mariam Aboian, Benedikt Wiestler, Ujjwal Baid, Gian Marco Conte, Andreas M. Rauschecker, Ayman Nada, Aly H. Abayazeed, Raymond Y. Huang, Maria Correia de Verdier, Jeffrey D. Rudie, Spyridon Bakas, and Evan Calabrese

Published
2024
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4. RTHP-27. PATTERNS OF FAILURE AFTER STEREOTACTIC RADIOSURGERY FOR RECURRENT HIGH-GRADE GLIOMA: A SINGLE INSTITUTION EXPERIENCE OF 10 YEARS

Author

Daniel L. Silbergeld, Eric C. Holland, Lia Halasz, Meghan W. Macomber, and Chibawanye I. Ene

Subjects
Patterns of failure, Cancer Research, medicine.medical_specialty, business.industry, medicine.medical_treatment, Radiosurgery, Abstracts, Oncology, parasitic diseases, Medicine, Neurology (clinical), Radiology, Single institution, business, High-Grade Glioma
Abstract

BACKGROUND: Stereotactic radiosurgery (SRS) is a treatment modality that is frequently used as salvage therapy for small nodular recurrent high grade gliomas (HGG). Due to the infiltrative nature of HGG, it is unclear if this highly focused technique provides a durable local control benefit. Objective To determine how demographic or clinical factors influence the pattern of failure following SRS for recurrent high grade gliomas. METHODS: We retrospectively reviewed clinical, radiographic and follow-up information for 47 consecutive patients receiving SRS for recurrent HGG at our institution between June 2006 and July 2016. All patients initially presented with a HGG (WHO Grade III and IV). Following SRS for recurrence, all patients experienced treatment failure, and we evaluated patterns of local, regional, and distant failure in relation to the SRS 50% isodose line. RESULTS: Most patients with recurrent HGG developed in-field treatment failure following SRS (N = 40; 85%). Higher SRS doses were associated with longer time-to-failure (HR = 0.80 per 1Gy increase; 95% CI 0.67–0.96; P = .016). There was a statistically significant increase in distant versus in-field failure among older patients (P=.035). This effect was independent of bevacizumab use (OR = 0.54, P =1.0). CONCLUSIONS: Based on our experience, the majority of treatment failures after SRS for recurrent HGG were in-field. Older patients, however, presented with more distant failures. Our results indicate that higher SRS doses delivered to a larger area as fractioned or unfractioned regimen may prolong time-to-failure, especially in the older population.

Published
2018

5. Contributors

Author

Isaac Josh Abecassis, Vijay Agarwal, Pankaj K. Agarwalla, Christopher S. Ahuja, Andrew Folusho Alalade, Saira Alli, Kristian Aquilina, Rocco A. Armonda, Lissa Baird, James W. Bales, Nicholas C. Bambakidis, Daniel L. Barrow, David F. Bauer, Jeffrey S. Beecher, Randy S Bell, Antonio Belli, Edward C. Benzel, Robert H. Bonow, Umberto Marcello Bracale, Samuel R. Browd, Ketan Bulsara, David W. Cadotte, Paolo Cappabianca, Luigi Maria Cavallo, Alvin Y. Chan, Roc Peng Chen, Peter A. Chiarelli, Omar Choudhri, Michelle Chowdhary, Jason Chu, Michael J. Cirivello, Pablo Picasso de Araújo Coimbra, Kelly L. Collins, Juliane Daartz, Oreste de Divitiis, Wolfgang Deinsberger, Simone E. Dekker, Michael C. Dewan, Salvatore Di Maio, Dale Ding, Richard G. Ellenbogen, Chibawanye Ene, Michael Fehlings, Flávio Leitão de Carvalho, James R. Fink, Kathleen R. Tozer Fink, Jared Fridley, George M. Ghobrial, Michael Gleeson, Atul Goel, Ziya L. Gokaslan, James Tait Goodrich, Gerald A. Grant, Bradley A. Gross, Joseph Gruss, Lia Halasz, Brian W. Hanak, Todd C. Hankinson, James S. Harrop, Carl B. Heilman, Robert S. Heller, S. Alan Hoffer, Christoph P. Hofstetter, Jonathan A. Hyam, Kate Impastato, Semra Isik, Greg James, R. Tushar Jha, Kristen E. Jones, Patrick K. Jowdy, Samuel Kalb, Robert F. Keating, Cory M. Kelly, Neil D. Kitchen, Andrew L. Ko, Matthew J. Koch, Douglas Kondziolka, Chao-Hung Kuo, A. Noelle Larson, Michael T. Lawton, Amy Lee, Michael R. Levitt, Elad I. Levy, Jay S. Loeffler, Timothy H Lucas, Suresh N. Magge, Edward M. Marchan, Henry Marsh, Alexander M. Mason, Panagiotis Mastorakos, D. Jay McCracken, Rajiv Midha, Ryan P. Morton, Kyle Mueller, Jeffrey P. Mullin, Mustafa Nadi, Peter Nakaji, John D. Nerva, Toba N. Niazi, Jeffrey G. Ojemann, Adetokunbo Oyelese, Nelson M. Oyesiku, Anoop P. Patel, Eric C. Peterson, David W. Polly, Helen Quach, Shobana Rajan, Ali Ravanpay, Leslie C. Robinson, Ricardo Rocha, Trevor J. Royce, James T. Rutka, Laligam N. Sekhar, Warren Selman, Ashish H. Shah, Hussain Shallwani, Deepak Sharma, Mohan Raj Sharma, Daniel L. Silbergeld, Dulanka Silva, Harley Brito da Silva, Luke Silveira, Edward Smith, Domenico Solari, Hesham Soliman, Teresa Somma, Robert M. Starke, David C. Straus, Charles Teo, Ahmed Toma, Yolanda D. Tseng, R. Shane Tubbs, Kunal Vakharia, Alessandro Villa, Scott D. Wait, Brian P. Walcott, Connor Wathen, John C. Wellons, Mark Wilson, Amparo Wolf, Linda Xu, Tong Yang, Christopher C. Young, and Ludvic Zrinzo

Published
2018
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