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102 results on '"Liang, Yiping"'

5. Surface Defect 3-D Profile Reconstruction Using Eddy Current Pulsed Thermography

Author

Zhang, Xu, Bai, Libing, Liang, Yiping, Yang, Jinsheng, Ai, Jiangshan, and Ren, Chao

Abstract

Accurately evaluating the 3-D profile of nonferromagnetic metal surface defects is essential for nondestructive evaluation. Eddy current pulsed thermography (ECPT) has been used for reconstructing surface defects, which utilizes multiphysics coupling of electromagnetic and thermal fields. Previous investigations mainly employ the thermal field for reconstruction. However, the thermal field varies slowly over time and has weak correlation, which causes serious blur and noise. In this article, a surface defect 3-D profile reconstruction method based on eddy current field distribution is proposed. The proposed method takes advantage of the strong global correlation of eddy current fields and proposes an inversion technique to reconstruct defects. Experimental results demonstrate that the proposed method can effectively reconstruct the 3-D profile of defects with depths within the skin depth, including complex-shaped defects and natural cracks.

Published
2024
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10. FKBP11 improves the malignant property in osteosarcoma cells and acts as a prognostic factor of osteosarcoma

Author

Zeng, Duo, primary, Li, Jiayu, additional, Yuan, Xuhui, additional, Cai, Feng, additional, Yu, Bo, additional, Liu, Lang, additional, Chen, Qinchan, additional, Zhang, FeiFei, additional, Liang, Yiping, additional, Tang, Xiaofeng, additional, Peng, Yuanxiang, additional, Qu, Gaoyang, additional, Wu, Pengyun, additional, Jiao, QuanHui, additional, Sun, Longhua, additional, Lv, Xiao-Bin, additional, and Liao, Qi, additional

Published
2023
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11. Adenosylhomocysteinase plays multiple roles in maintaining the identity and pluripotency of mouse embryonic stem cells†

Author

Jiang, Qi, Lan, Shubing, Tan, Fancheng, Liang, Yiping, Guo, Zhencheng, Hou, Yanlin, Zhang, Hui, Wu, Guangming, and Liu, Zhonghua

Abstract

Adenosylhomocysteinase (AHCY), a key enzyme in the methionine cycle, is essential for the development of embryos and the maintenance of mouse embryonic stem cells (mESCs). However, the precise underlying mechanism of Ahcyin regulating pluripotency remains unclear. As the only enzyme that can hydrolyze S-adenosylhomocysteine in mammals, AHCY plays a critical role in the metabolic homeostasis, epigenetic remodeling, and transcriptional regulation. Here, we identified Ahcyas a direct target of OCT4 and unveiled that AHCY regulates the self-renewal and differentiation potency of mESCs through multiple mechanisms. Our study demonstrated that AHCY is required for the metabolic homeostasis of mESCs. We revealed the dual role of Ahcyin both transcriptional activation and inhibition, which is accomplished via the maintenance of H3K4me3 and H3K27me3, respectively. We found that Ahcyis required for H3K4me3-dependent transcriptional activation in mESCs. We also demonstrated that AHCY interacts with polycomb repressive complex 2 (PRC2), thereby maintaining the pluripotency of mESCs by sustaining the H3K27me3-regulated transcriptional repression of related genes. These results reveal a previously unrecognized OCT4–AHCY–PRC2 axis in the regulation of mESCs’ pluripotency and provide insights into the interplay between transcriptional factors, cellular metabolism, chromatin dynamics and pluripotency regulation.Our results reveal a previously unrecognized OCT4–AHCY–PRC2 axis in the regulation of mESCs’ pluripotency and shed light on the interplay between transcriptional factors, cellular metabolism, chromatin dynamics and pluripotency regulation.Graphical Abstract

Published
2024
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12. Enhanced Diffusion-Based Analysis for Fast Defect Detection in ECPT Image

Author

Liang, Yiping, Bai, Libing, Tian, Lulu, Zhang, Xu, Ren, Chao, Shao, Dan, Ma, Zhenzhong, and Sun, Mosi

Abstract

Eddy current pulsed thermography (ECPT) has attracted much attention in nondestructive testing for its noncontact and large field of view. However, the ECPT images usually suffer from the thermal diffusion blurs. The fusion of temperature spatial and temporal features is the hotspot in the new research of ECPT enhancing methods, but these two features are contradictory on the speed and the accuracy of algorithms. Specifically, spatial features process fast but perform poorly in accuracy and antinoise ability, while temporal features are usually calculated from the whole ECPT video sequence, which inevitably increases the demand for data storage and the time cost, especially in the detection of large workpieces, such as engine blades or pressure pipelines. In this article, an enhanced diffusion-based method (EDBM) is proposed to solve this issue, which maps the temporal features through the spatial features of a single ECPT image, significantly reduces the input data volume and shows great potential in ECPT online detection. Experiments on multiple artificial and natural samples verify that, compared with raw ECPT image, the proposed EDBM can reduce root-mean-square error by 51.7%–86.5% (73.2% on average) and improve signal-to-noise ratio by 3.70–16.8 times (6.82 times on average), which performs better than the commonly spatial-based and temporal-based ECPT enhancement algorithms, such as enhanced Canny and independent component analysis, close to the latest sparse-model decomposition methods, but with two orders of magnitude less time cost.

Published
2024
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13. Induced Current Thermo-Electrical Impedance Tomography for Nonferromagnetic Metal Material Surface Defect Profile Reconstruction

Author

Zhang, Xu, Bai, Libing, Zhang, Jie, Liang, Yiping, Cheng, Yuhua, Tian, Lulu, and Duan, Yong

Abstract

Nonferromagnetic metal materials are widely used in industry. Defects generated during manufacture and use may lead to serious accidents. The defect reconstruction is important for nondestructive evaluation. Eddy current pulsed thermography (ECPT) is a well-known nondestructive testing and evaluation method, but hardly reconstruct fully defect profile. Electrical impedance tomography (EIT) shows promising potential in defect profile reconstruction, but suffers from electrode number limitation. In this article, EIT is introduced to ECPT image sequences processing, and a new method, induced current thermo-electrical impedance tomography, is developed. The proposed method takes each infrared camera pixel as a virtual electrode, captures the electric current distribution with spatial resolution as high as camera, and reconstructs conductivity distribution at pixel level from which the defect profile can be identified. Experiments with different defects are carried out to verify the performance of the proposed method.

Published
2024
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17. Additional file 1 of The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma

Author

Yu, Bo, Liu, Lang, Cai, Feng, Peng, Yuanxiang, Tang, Xiaofeng, Zeng, Duo, Li, Teng, Zhang, Feifei, Liang, Yiping, Yuan, Xuhui, Li, Jiayu, Dai, Zhengzai, Liao, Qi, and Lv, Xiao-Bin

Abstract

Additional file 1: Figure S1. The two inhibitors had almost no toxic effects in normal osteosarcoma cell line (hFOB 1.19) and 293T cells. (A) The concentrations of MG63, U2OS, 143B and MNNG cells treated by OTX015/WT-161 for the synergistic assay. (B) CCK-8 was used to detect cell proliferation in MG63 and U2OS after they were treated separately with various doses of OTX015 or WT-161 for 48 h. (C) The IC50 of OTX015 and WT-161 in hFOB 1.19 and 293T cells. (D) The single and combined treatment doses of OTX015 and WT-161 for 48 h for the further assays.

Published
2022
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22. The Synergistic Anticancer Effect of Bromodomain Inhibitor OTX015 and Histone Deacetylase 6 Inhibitor WT-161 in Osteosarcoma

Author

Yu, Bo, primary, Liu, Lang, additional, Cai, Feng, additional, Peng, Yuanxiang, additional, Tang, Xiaofeng, additional, Zeng, Duo, additional, Li, Teng, additional, Zhang, Feifei, additional, Liang, Yiping, additional, Yuan, Xuhui, additional, Li, Jiayu, additional, Dai, Zhengzai, additional, Liao, Qi, additional, and Lv, Xiao-Bin, additional

Published
2021
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23. The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway

Author

Yu, Bo, primary, Zhang, Feifei, additional, Liu, Lang, additional, Liang, Yiping, additional, Tang, Xiaofeng, additional, Peng, Yuanxiang, additional, Cai, Feng, additional, Zeng, Duo, additional, Yuan, Xuhui, additional, Li, Jiayu, additional, Guo, Yuhong, additional, Lv, Bin, additional, Wang, Min, additional, Liao, Qi, additional, and Lv, Xiao-Bin, additional

Published
2021
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25. HDAC6 inhibitor WT161 performs anti-tumor effect on osteosarcoma and synergistically interacts with 5-FU

Author

Sun, Jun, primary, Wu, Wei, additional, Tang, Xiaofeng, additional, Zhang, Feifei, additional, Ju, Cheng, additional, Liu, Renfeng, additional, Liang, Yiping, additional, Yu, Bo, additional, Lv, Bin, additional, Guo, Yuhong, additional, Zeng, Duo, additional, Tao, Xuchang, additional, Wang, Min, additional, Zhang, Zhiping, additional, Zhang, Changhua, additional, and Lv, Xiao-Bin, additional

Published
2021
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28. Stabilization of SAMHD1 by NONO is Crucial for Ara-C Resistance in AML

Author

Zhang, Feifei, primary, Sun, Jun, additional, Tang, Xiaofeng, additional, Liang, Yiping, additional, Jiao, Quanhui, additional, Yu, Bo, additional, Dai, Zhengzai, additional, Yuan, Xuhui, additional, Li, Jiayu, additional, Yan, Jinhua, additional, Zhang, Zhiping, additional, Fan, Song, additional, Wang, Min, additional, Hu, Haiyan, additional, Zhang, Changhua, additional, and Lv, Xiao-Bin, additional

Published
2021
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29. Identification of BRMS1L as Metastasis Suppressing Gene in Esophageal Squamous Cell Carcinoma

Author

Zhou,Ruihao, Tang,Xiaofeng, Li,Liping, Zhang,Feifei, Sun,Jun, Ju,Cheng, Zhou,Yan, Liu,Renfeng, Liang,Yiping, Lv,Bin, Zhang,Zhiping, Hu,Haiyan, and Lv,Xiao-Bin

Subjects
Cancer Management and Research
Abstract

Ruihao Zhou, 1, 2,* Xiaofeng Tang, 1,* Liping Li, 3,* Feifei Zhang, 1 Jun Sun, 1 Cheng Ju, 1, 4 Yan Zhou, 5 Renfeng Liu, 1, 4 Yiping Liang, 1 Bin Lv, 1, 4 Zhiping Zhang, 1, 4 Haiyan Hu, 5 Xiao-Bin Lv 1 1Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, The Third Affiliated Hospital of Nanchang University, Nanchang 30008, People’s Republic of China; 2Department of Pain Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, People’s Republic of China; 3Department of Clinical Laboratory, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, People’s Republic of China; 4Department of Orthopedics, The Third Affiliated Hospital of Nanchang University,Nanchang 330008, People’s Republic of China; 5Department of Oncology,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital of Shanghai, Shanghai 200233, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Bin LvJiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, The Third Affiliated Hospital of Nanchang University, North 128 Xiangshan Road, Nanchang 30008, Jiangxi, People’s Republic of ChinaEmail nclvxiaobin@sina.cnHaiyan HuDepartment of Oncology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, No. 600 Yishan Road, Xuhui District, Shanghai City 200233, People’s Republic of ChinaEmail xuri1104@163.comIntroduction: Breast cancer metastasis suppressor 1 like (BRMS1-like)was first reported to be a component of the Sin3-HDAC complex, but the role in the progression of cancers was largely unknown. Our previous study reported that BRMS1L promoted the metastasis of breast cancer through facilitating the recruitment of HDAC complex to the promoter FZD10, and hence suppressing the transcription of FZD10.Methods: In this study, we detected the expression level of BRMS1L in esophageal squamous cell carcinoma (ESCC). The effect of BRMS1L in TE-1D (knockdown) and ECA-109 (overexpression) cell lines was explored by transwell assays, wound healing assays, and cell adhesion assays. Quantitative real‑time PCR, Western blot analysis, and luciferase assays were used to detect the interaction of the CBP/P300-BRMS1L-ITGA7 axis.Results: In the present study, we found that knockdown of BRMS1L promoted the migration, invasion, and epithelial–mesenchymal transition (EMT). Conversely, overexpression of BRMS1L inhibited the migration and invasion of ESCC. Mechanistically, BRMS1L exerted their metastasis-suppressing role via transcriptionally repress ITGA7 expression. Moreover, we revealed that CBP/p 300 regulated the expression of BRMS1L and might be responsible for the down-regulation of BRMS1L in ESCC.Conclusion: Collectively, we identified the role of CBP/p300-BRMS1L-ITGA7 axis in the metastasis of ESCC.Keywords: BRMS1L, ESCC, EMT, ITGA7, CBP/P300, cell invasion and migration

Published
2020

32. HDAC6 Inhibitor WT161 Performs Antitumor Effect on Ostersarcoma and Synergistically Interacts with 5-FU

Author

Sun, Jun, primary, Tang, Xiaofeng, additional, Zhang, Feifei, additional, Ju, Cheng, additional, Liu, Renfeng, additional, Liang, Yiping, additional, Yu, Bo, additional, Lv, Bin, additional, Guo, Yuhong, additional, Zeng, Duo, additional, Wang, Min, additional, Zhang, Zhiping, additional, Zhang, Changhua, additional, and Lv, Xiao-Bin, additional

Published
2020
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35. A Partial-Coherence Model Describingthe Far-Field Distribution of Laser Diode

Author

熊玲玲 Xiong Lingling, 赵东升 Zhao Dongsheng, 梁一平 Liang Yiping, 戴特力 Dai Teli, and 何华伟 He Huawei

Subjects
Physics, Optics, Laser diode, Distribution (number theory), business.industry, law, Near and far field, business, Atomic and Molecular Physics, and Optics, Partial coherence, Electronic, Optical and Magnetic Materials, law.invention
Published
2010

36. Finite Element Analysis of Thermal Management in Optical Pumping Semiconductor Vertical-External Cavity Surface-Emitting Laser

Author

陈柏众 Chen Baizhong, 梁一平 Liang Yiping, 戴特力 Dai Teli, 赵红 Zhao Hong, 周勇 Zhou Yong, 秦莉 Qin Li, and 程立文 Cheng Liwen

Subjects
Distributed feedback laser, Materials science, business.industry, Thermal management of electronic devices and systems, Vertical-external-cavity surface-emitting-laser, Atomic and Molecular Physics, and Optics, Finite element method, Electronic, Optical and Magnetic Materials, Optical pumping, Semiconductor, Optoelectronics, Semiconductor optical gain, Electrical and Electronic Engineering, business
Published
2009

37. Studies on the Spontaneous Evolution of Small Particle Aggregations

Author

Pan Chunyan, Deng Zhaojing, Li Jian, and Liang Yiping

Subjects
Biomaterials, Physics, Colloid, Theoretical physics, Colloid and Surface Chemistry, Chemical physics, Particle, Small particles, Agrégation, Fractal dimension, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials
Abstract

On the basis of the criteria for spontaneous evolution of small particle aggregations, which are described by D. Zhaojing, L. Yiping, and L. Cunye [J. Colloid Interface Sci.173,79 (1995)], and according to the results of the experiments and simulations, the spontaneous evolution process of small particle aggregations is further discussed in detail.

Published
1996

42. Optimization of Pump Pulses in a Vertical-External-Cavity Surface-Emitting Laser

Author

张玉 Zhang Yu, 范嗣强 Fan Siqiang, 蒋茂华 Jiang Maohua, 梁一平 Liang Yiping, 戴特力 Dai Teli, and 张鹏 Zhang Peng

Subjects
Optics, Materials science, business.industry, Laser power scaling, Electrical and Electronic Engineering, business, Vertical-external-cavity surface-emitting-laser, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published
2013

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