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5. Author Correction: Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

Author

Park, Ji Hye, Kim, Hyeok, Moon, Hyung Ryong, Park, Bong-Woo, Park, Jae-Hyun, Sim, Woo-Sup, Kim, Jin-Ju, Lim, Hye Ji, Kim, Yeon-Ju, Ji, Seung Taek, Jang, Woong Bi, Rethineswaran, Vinoth Kumar, Van, Le Thi Hong, Giang, Ly Thanh Truong, Yun, Jisoo, Ha, Jong Seong, Ban, Kiwon, Chung, Hae Young, Baek, Sang Hong, Park, Hun-Jun, and Kwon, Sang-Mo

Published
2022
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6. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

Author

Park, Ji Hye, Kim, Hyeok, Moon, Hyung Ryong, Park, Bong-Woo, Park, Jae-Hyun, Sim, Woo-Sup, Kim, Jin-Ju, Lim, Hye Ji, Kim, Yeon-Ju, Ji, Seung Taek, Jang, Woong Bi, Rethineswaran, Vinoth Kumar, Van, Le Thi Hong, Giang, Ly Thanh Truong, Yun, Jisoo, Ha, Jong Seong, Ban, Kiwon, Chung, Hae Young, Baek, Sang Hong, Park, Hun-Jun, and Kwon, Sang-Mo

Published
2021
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7. Corrigendum to “Non-intrusive quality appraisal of differentiation-induced cardiovascular stem cells using E-Nose sensor technology” [Biosens. Bioelectron., 246 (2024) 115838]

Author

Nguyen, Thanh Mien, primary, Jang, Woong Bi, additional, Lee, Yujin, additional, Kim, You Hwan, additional, Lim, Hye Ji, additional, Lee, Eun Ji, additional, Nguyen, Thu M.T., additional, Choi, Eun-Jung, additional, Kwon, Sang-Mo, additional, and Oh, Jin-Woo, additional

Published
2024
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10. 3D-bioprinted bone scaffolds incorporating SR1 nanoparticles enhance blood vessel regeneration in rat calvarial defects

Author

Yang, KyeongWoong, primary, Lee, Donghyun, additional, Lee, Kyoung Ho, additional, Jang, Woong Bi, additional, Lim, Hye Ji, additional, Lee, Eun Ji, additional, Jeon, Hojun, additional, Kang, Donggu, additional, Yang, Gi Hoon, additional, Lee, KyeongHyeon, additional, Shin, Yong-Il, additional, Han, Sang-Cheol, additional, An, SangHyun, additional, and Kwon, Sang-Mo, additional

Published
2024
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11. Lactobacillus fermentum attenuates the alveolar bone loss in ligature‐induced periodontitis in mice.

Author

Lee, Yuni, Jung, Bo Hyun, Yoo, Ki‐Yeon, Lim, Hye Ji, Shin, Kum‐Joo, and Lee, Jae‐Kwan

Subjects
INFLAMMATION prevention, BONE resorption, BIOLOGICAL models, RESEARCH funding, BONE density, COMPUTED tomography, DESCRIPTIVE statistics, IN vivo studies, MICE, LACTOBACILLUS, ANIMAL experimentation, HISTOLOGICAL techniques, PROBIOTICS, CYTOKINES, COMPARATIVE studies, PERIODONTITIS, DISEASE progression, CONNECTIVE tissues
Abstract

Objective: This study investigated the effects of Lactobacillus fermentum BELF11 on periodontitis in mice (LIP). Methods: Sixty mice were randomly assigned to a control group (CTL), LIP/PBS group (LIP and PBS applied), or LIP/BELF11 group (LIP and L. fermentum BELF11 applied). For 14 days, PBS or L. fermentum BELF11 was applied twice daily to the mice in the LIP/PBS or LIP/BELF11 group, respectively. After 14 days, radiographic, histological, and pro‐inflammatory cytokine assessments were conducted. Results: The LIP/PBS and LIP/BELF11 groups demonstrated greater alveolar bone loss than the CTL group (p < 0.05). The LIP/BELF11 group showed significantly reduced alveolar bone loss on the mesial side compared to the LIP/PBS group. Histologically, the LIP/BELF11 group showed consistent patterns of connective tissue fiber arrangement, lower levels of inflammatory infiltration, less alveolar bone loss, and higher alveolar bone density than the LIP/PBS group, despite showing more signs of destruction than the CTL group. The LIP/BELF11 group also exhibited significantly lower levels of pro‐inflammatory cytokines than the LIP/PBS group. Conclusions: L. fermentum BELF11 inhibits alveolar bone loss and periodontitis progression by regulating pro‐inflammatory cytokine production. These findings suggest that L. fermentum BELF11 may be a potential adjunctive therapy in periodontal treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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14. StemRegenin-1 Attenuates Endothelial Progenitor Cell Senescence by Regulating the AhR Pathway-Mediated CYP1A1 and ROS Generation

Author

Lim, Hye Ji, primary, Jang, Woong Bi, additional, Rethineswaran, Vinoth Kumar, additional, Choi, Jaewoo, additional, Lee, Eun Ji, additional, Park, Sangmi, additional, Jeong, Yeoreum, additional, Ha, Jong Seong, additional, Yun, Jisoo, additional, Choi, Young Jin, additional, Hong, Young Joon, additional, and Kwon, Sang-Mo, additional

Published
2023
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18. Engineered M13 Peptide Carrier Promotes Angiogenic Potential of Patient-Derived Human Cardiac Progenitor Cells and In VivoEngraftment

Author

Jang, Woong Bi, Ji, Seung Taek, Park, Ji Hye, Kim, Yeon-Ju, Kang, Songhwa, Kim, Da Yeon, Lee, Na-Kyung, Kim, Jin Su, Lim, Hye Ji, Choi, Jaewoo, Le, Thi Hong Van, Ly, Thanh Truong Giang, Rethineswaran, Vinoth Kumar, Kim, Dong Hwan, Ha, Jong Seong, Yun, Jisoo, Baek, Sang Hong, and Kwon, Sang-Mo

Abstract

Background:: Despite promising advances in stem cell-based therapy, the treatment of ischemic cardiovascular diseases remains a big challenge due to both the insufficient in vivoviability of transplanted cells and poor angiogenic potential of stem cells. The goal of this study was to develop therapeutic human cardiac progenitor cells (hCPCs) for ischemic cardiovascular diseases with a novel M13 peptide carrier. Method:: In this study, an engineered M13 peptide carrier was successfully generated using a QuikChange Kit. The cellular function of M13 peptide carrier-treated hCPCs was assessed using a tube formation assay and scratch wound healing assay. The in vivoengraftment and cell survival bioactivities of transplanted cells were demonstrated by immunohistochemistry after hCPC transplantation into a myocardial infarction animal model. Results:: The engineered M13RGD+SDKPpeptide carrier, which expressed RGD peptide on PIII site and SDKP peptide on PVIII site, did not affect morphologic change and proliferation ability in hCPCs. In contrast, hCPCs treated with M13RGD+SDKPshowed enhanced angiogenic capacity, including tube formation and migration capacity. Moreover, transplanted hCPCs with M13RGD+SDKPwere engrafted into the ischemic region and promoted in vivocell survival. Conclusion:: Our present data provides a promising protocol for CPC-based cell therapy via short-term cell priming of hCPCs with engineered M13RGD+SDKPbefore cell transplantation for treatment of cardiovascular disease.

Published
2024
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20. Therapeutic Cell Protective Role of Histochrome under Oxidative Stress in Human Cardiac Progenitor Cells

Author

Park, Ji Hye, primary, Lee, Na-Kyung, additional, Lim, Hye Ji, additional, Mazumder, Sinthia, additional, Kumar Rethineswaran, Vinoth, additional, Kim, Yeon-Ju, additional, Jang, Woong Bi, additional, Ji, Seung Taek, additional, Kang, Songhwa, additional, Kim, Da Yeon, additional, Van, Le Thi Hong, additional, Giang, Ly Thanh Truong, additional, Kim, Dong Hwan, additional, Ha, Jong Seong, additional, Yun, Jisoo, additional, Kim, Hyungtae, additional, Han, Jin, additional, Mishchenko, Natalia P., additional, Fedoreyev, Sergey A., additional, Vasileva, Elena A., additional, Kwon, Sang Mo, additional, and Baek, Sang Hong, additional

Published
2019
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