Search

Min-Kyung Ji,1,* Yaerim Chun,2,* Geonwoo Jeong,3 Hyun-Seung Kim,4 Won-Jae Kim,5 Je-Hwang Ryu,6 Hoonsung Cho,3 Hyun-Pil Lim1,2 1Dental 4D Research Center, Chonnam National University, Gwangju, Republic of Korea; 2Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea; 3Department of Materials Science and Engineering, Chonnam National University, Gwangju, Republic of Korea; 4KJ Meditech Co., Ltd, Gwangju, Republic of Korea; 5Department of Oral Physiology, School of Dentistry, Stem Cell Secretome Research Center, Chonnam National University, Gwangju, Republic of Korea; 6Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea*These authors contributed equally to this workCorrespondence: Hyun-Pil Lim, Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel +82-10-2645-7528, Fax +82-62-530-5577, Email mcnihil@jnu.ac.kr Hoonsung Cho, Department of Materials Science and Engineering, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel/Fax +82-62-530-1717, Email cho.hoonsung@jnu.ac.krPurpose: This study aimed to confirm the synergy effect of these two materials by evaluating osteoblast and antibacterial activity by applying a double-layered hydroxyapatite(HA) zirconium oxide(ZrO2) coating to titanium.Methods: The specimens used in this study were divided into four groups: a control group (polished titanium; group T) and three experimental groups: Group TH (RF magnetron sputtered HA deposited titanium), Group Z (ZrO2 ALD deposited titanium), and Group ZH (RF magnetron sputtered HA and ZrO2 ALD deposited titanium). The adhesion of Streptococcus mutans (S.mutans) to the surface was assessed using a crystal violet assay. The adhesion, proliferation, and differentiation of MC3T3-E1 cells, a mouse osteoblastic cell line, were assessed through a WST-8 assay a

Hong-Joo Kim,1 Seon-Ki Lee,2 Hyun-Seung Kim,3 Won-Jae Kim,4 Je-Hwang Ryu,5 Min-Kyung Ji,6 Hyun-Pil Lim1 1Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea; 2Department of Prosthodontics, Daejeon Dental Hospital, Wonkwang University, Daejeon, Republic of Korea; 3KJ Meditech Co., Ltd, Gwangju, Republic of Korea; 4Department of Oral Physiology, School of Dentistry, Stem cell Secretome Research Center, Chonnam National University, Gwangju, Republic of Korea; 5Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea; 6Dental 4D Research Center, Chonnam National University, Gwangju, Republic of KoreaCorrespondence: Hyun-Pil Lim, Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel +82-10-2645-7528, Fax +82-62-530-5639, Email mcnihil@jnu.ac.kr Min-Kyung Ji, Dental 4D Research Center, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel +82-10-8432-3639, Fax +82-62-530-5639, Email perizimin@gmail.comPurpose: Atomic layer deposition (ALD) is a method that can deposit zirconia uniformly on an atomic basis. The effect of deposited zirconia on titanium implants using ALD was evaluated in vivo.Methods: Machined titanium implants (MTIs) were used as the Control. MTIs treated by sandblasting with large grit and acid etching (SA) and MTIs deposited with zirconia using ALD are referred to as Groups S and Z, respectively. Twelve implants were prepared for each group. Six rabbits were used as experimental animals. To evaluate the osteogenesis and osteocyte aspects around the implants, radiological and histological analyses were performed. The bone-to-implant contact (BIC) ratio was measured and statistically analyzed to evaluate the osseointegration capabilities.Results: In the micro-CT analysis, more radiopaque bone tissues were observed around the implants in Groups S and Z. H

Hee-Seon Kim,1,* Woohyung Jang,1,* Yeong-Gwan Im,2 Hyun-Pil Lim1 1Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea; 2Department of Oral Medicine, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea*These authors contributed equally to this workCorrespondence: Hyun-Pil Lim, Department of Prosthodontics, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel +82-62-530-5577, Email mcnihil@jnu.ac.kr Yeong-Gwan Im, Department of Oral Medicine, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea, Tel +82-62-530-5578, Email imygwise@jnu.ac.krObjective: Mid-to-long term use of provisional crowns in the oral cavity is associated with bacterial adhesion and biofilm formation, thus necessitating provisional crowns exhibiting antibacterial properties to prevent the occurrence of gingivitis and periodontal disease. This study aimed to evaluate the antibacterial effect of zirconia nanoparticle-containing polyethyl methacrylate (PEMA) resin for provisional restorations.Methods: Zirconia nanoparticles were added to the monomer of PEMA resin for provisional restorations, and the mixture was stirred for 2 h using a magnetic stirrer. Disk-shaped specimens were prepared by mixing the polymer with the nanoparticle solution. The control group contained pure PEMA resin samples, and the experimental groups Group Z2, Group Z4, and Group Z8 included PEMA resin specimens containing 2, 4, and 8% w/v zirconia nanoparticles, respectively. After analyzing the sample surfaces, the antibacterial effect of the specimens was evaluated using Streptococcus mutans. Statistical analysis was performed using Tukey’s test and Mann–Whitney U-test, according to the normality result in the Shapiro–Wilk test.Results: FE-SEM and EDX analyses revealed the successful addition of zirconia nanoparticles. Results showed no sig