84 results on '"Lin, Jun-Li"'
Search Results
2. Neoadjuvant camrelizumab plus chemotherapy in locally advanced oesophageal squamous cell carcinoma: a retrospective cohort study
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Rui-Qin Zhou, Jun Luo, Lin-Jun Li, Ming Du, and Qing-Chen Wu
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Oesophageal squamous cell carcinoma (ESCC) ,Neoadjuvant chemotherapy ,Immunotherapy ,Camrelizumab ,Docetaxel ,Nedaplatin ,Surgery ,RD1-811 - Abstract
Abstract Background Neoadjuvant therapy is recommended to improve the prognosis of oesophageal squamous cell carcinoma (ESCC). As a PD-1 inhibitor developed in China, camrelizumab is more accessible and available for Chinese ESCC patients. Camrelizumab plus neoadjuvant chemotherapy has shown promising efficacy with acceptable toxicity for resectable ESCC in the NIC-ESCC2019 trial. However, this was a single-arm trial, so we conducted a retrospective cohort study to compare neoadjuvant camrelizumab plus chemotherapy with neoadjuvant chemotherapy alone in terms of the safety and efficacy in patients with locally advanced ESCC. Methods Between January 2017 and December 2021, patients with stage II–IVa ESCC who received neoadjuvant therapy at the First Affiliated Hospital of Chongqing Medical University and underwent radical oesophagectomy were enrolled in our study. These included 19 patients who received neoadjuvant chemotherapy plus camrelizumab (group 1) and 40 patients who only received neoadjuvant chemotherapy (group 2). Results The baseline characteristics of the patients were comparable between the two groups. The pathological complete response (pCR) rate in group 1 was significantly higher than that in group 2 (26.3% vs. 2.5%, P = 0.018). All patients in group 1 achieved complete resection (R0), compared with 39 (97.5%) patients in group 2. Adverse events occurred in 16 (84%) patients in group 1 versus 35 (87.5%) patients in group 2. No grade ≥ 4 adverse events occurred in either group. No significant difference was found in surgical outcomes or postoperative complications. The 90-day mortality rate was comparable between the two groups (1 patient died in group 1 versus 2 patients in group 2). Conclusions Neoadjuvant camrelizumab plus chemotherapy followed by surgery was associated with a promising pCR rate and a manageable safety profile for patients with locally advanced ESCC.
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- 2023
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3. Advancing the Creative Development of Cultural Resources in LAMs for Serving China's Cultural Development Strategy
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WANG Yi, KE Ping, DING Huadong, WANG Yujue, ZENG Shizhan, HUANG Yang, LIN Jun, LI Nan, DENG Yongqiu
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development of cultural resources ,library ,archives ,museum ,cultural creativity ,interdisciplinary integration ,Bibliography. Library science. Information resources ,Agriculture - Abstract
Various kinds of cultural resources collected in libraries, archives and museums (LAMs) are an important part of the profound and splendid culture that has been created in the development process of China's civilization. Relying on the cultural resources in the collections of LAMs, the creative development of resources is conducive to promoting the creative transformation and innovative development of the excellent traditional Chinese culture. Similarly, it is also the important means to enrich the spiritual and cultural life of the people and to meet the diversified consumer needs. Moreover, it is the inevitable requirement to enhance the service capacity of institutions, improve the service level and enrich the service content. In order to better promote the integration and reference of theory and practice in the creative development of cultural resources in LAMs, and improve the theoretical level and experience of creative cultural research, 7 experts were invited to attend the seminar on relevant theory and practice: (1) To construct cultural creativity with Chinese characteristics: it is suggested that the development of cultural creativity be elevated to the height of serving the national strategy, so that the theoretical research of cultural creativity could be further strengthened, and the relevant research of cultural creativity could be developed as an important interdisciplinary field. (2) Creative development of cultural resources and reproduction of social memory: social memory is not only the core of cultural elements, but also the meaning framework or conceptual framework for understanding the value of cultural creative products. The article puts forward some suggestions and strategies, such as establishing the dialogue and communication mechanism of LAMs, expanding cultural and creative ways of thinking around the reproduction of the form of memory-content-meaning, and focusing on digital humanities to promote the transformation and development of cultural and creative products in LAMs. (3) The creative development of literature resources under the national culture digitization strategy: institutions such as libraries and archives begin to strive for the digital creative transformation of cultural resources, which provides reference for the digital upgrading of the development of creative products of literature resources in our country. (4) Thinking on the development of cultural creative products in museums: museums inherit and disseminate excellent traditional culture through innovative cultural products as the medium, help these products reach consumers and gain wide popularity through various means. This article summarizes the problems in the practice of cultural innovation in museums, and thinks about the road to sustainable development in the future while people are rejoicing in the cultural innovation craze in museums. (5) The practice and thinking of cultural innovation in libraries: based on the analysis of the similarities and differences between libraries and museums in cultural innovation, the paper summarizes the problems in practice and puts forward a new path of cultural innovation in libraries. (6) It is a successful case that the National Library of China conducts cultural and creative development in the way of enterprise operation. Not only does it start innovate ways of protecting and inheriting classics, make classic works come alive, improve the level of utilize classics and realize leapfrog development of cultural and creative works, but also it is of great significance to innovate the ways of library services and enhance the influence and competitiveness of library services. (7) Thinking on the creative development of "Library Gifts" series: the paper summarizes the cases and experiences of "Library Gifts" series' cultural and creative development in the National Library of China, and puts forward some opinions on the development of cultural and creative products by libraries.
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- 2022
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4. Refractory post-thymectomy myasthenia gravis with onset at MGFA stage V: a case report
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Rui-Qin Zhou, Lin-Jun Li, and Qing-Chen Wu
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Post-thymectomy myasthenia gravis ,Case report ,Thymoma ,Infection ,Misdiagnose ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Post-thymectomy myasthenia gravis (PTMG) is defined as thymoma patients without signs of myasthenia gravis (MG) pre-operation, but develop MG after radical surgical resection. PTMG might be misdiagnosed not only because of its rare incidence, but also the uncertain interval between the removal of thymoma and the new onset MG. Additionally, some surgeons and anesthesiologists pay less attention to those asymptomatic thymoma patients in perioperative management, leading to the neglect of new onset PTMG, and miss the best time to treat it. Case presentation Majority of cases of PTMG with onset at stage I–II on the basis of Myasthenia Gravis Foundation of America (MGFA) classification have been reported, but rarely at stage V, which requiring intubation or non-invasive ventilation to avoid intubation. Herein, we presented a 70-year-old male with PTMG onset at MGFA stage V, meanwhile, he had severe pulmonary infection interfering with the diagnosis of PTMG, and eventually progressed to refractory PTMG, which requiring much more expensive treatments and longer hospital stays. Conclusion In the perioperative management of asymptomatic thymoma patients, careful preoperative evaluation including physical examination, electrophysiological test and acetylcholine receptor antibodies (AChR-Ab) level should be done to identify subclinical MG. Complete resection should be performed during thymectomy, if not, additional postoperative adjuvant therapy is neccessary to avoid recurrence. It’s important to identify PTMG at a early stage, especially when being interfered with by postoperative complications, such as lung infection, so that treatments could be initiated as soon as possible to avoid developing to refractory PTMG.
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- 2022
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5. Study of the Mechanical Behavior of the Hydride Blister/Rim Structure in Zircaloy-4 using in-situ Synchrotron X-ray Diffraction
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Lin, Jun-li, Han, Xiaochun, Heuser, Brent J., and Almer, Jonathan D.
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Condensed Matter - Materials Science - Abstract
High-energy synchrotron X-ray diffraction was utilized to study the mechanical response of the f.c.c $\delta$-hydride phase, the intermetallic precipitation with hexagonal C14 lave phase and the $\alpha$-Zr phase in the Zircaloy-4 materials with a hydride rim/blister structure near one surface of the material during in-situ uniaxial tension experiment at 200 \si{\degreeCelsius}. The f.c.c $\delta$ was the only hydride phase observed in the rim/blister structure. The conventional Rietveld refinement was applied to measure the macro-strain equivalent response of the three phases. Two regions were delineated in the applied load versus lattice strain measurement: a linear elastic strain region and region that exhibited load partitioning. Load partitioning was quantified by von Mises analysis. The three phases were observed to have similar elastic modulus at 200 \si{\degreeCelsius}.
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- 2015
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6. Microstructure, Hardness, and Residual Stress of the Dissimilar Metal Weldments of SA508-309L/308L-304L
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Zhong, Weicheng, Lin, Jun-Li, Chen, Yan, Li, Zhen, An, Ke, Sutton, Benjamin J., and Heuser, Brent J.
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- 2021
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7. Vibrational modes and quantum zero-point energy of hydrogen in ZrH0.0155 and ZrH2
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Prisk, Timothy R., Kolesnikov, Alexander I., Granroth, Garrett E., Lin, Jun-Li, and Heuser, Brent J.
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- 2020
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8. Relationship between Water Use and Energy Generation from Different Power Generation Types in a Megacity Facing Water Shortages: A Case Study in Shenzhen
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Lin-Jun Li, Guo-Yu Qiu, and Chun-Hua Yan
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cooling water ,megacity ,power plants ,water and energy ,water use efficiency ,Hydraulic engineering ,TC1-978 ,Water supply for domestic and industrial purposes ,TD201-500 - Abstract
Using less water to generate more power is a goal of the worldwide power industry, but this is difficult to achieve because of the lack of long-term, operational data-based studies. This challenge is especially severe for megacities facing water shortages. This study used long-term data (2005–2015) from Shenzhen, a megacity of over 20 million people that faces severe water shortages, to determine the relationship between water and energy for different types of power generation. It was found that power generation consumed huge amounts of water and that cooling water was the biggest water use category. Smaller power plants, such as the Yueliangwan power plant, which uses the closed cooling method, consume 2.36 million m3 of tap water per year, equivalent to the water supply of a small reservoir. However, larger power plants, such as the Mawan power plant and Dayawan nuclear power plant (using the open cooling method), use 0.92 and 3.42 billion m3 of seawater for cooling every year, respectively, equivalent to about 60% and 200% of the total annual water supply in Shenzhen, respectively. Therefore, large thermal power plants and nuclear power plants should be built in coastal areas with rich water resources rather than in arid or semi-arid areas. Additionally, the water use efficiency of nuclear power plants was found to be 0.22 m3/kWh, which was significantly lower than that of coal-fired power plants (0.10 m3/kWh) and gas-fired power plants (0.09 m3/kWh). Third, the water use efficiency of the closed cooling method was ten times higher than that of the open cooling method. Therefore, the closed cooling method is suitable for power plants constructed in areas without rich water resources. These results are useful for balancing the water and energy demands in the changing world.
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- 2022
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9. Modeling hydrogen solvus in zirconium solution by the mesoscale phase-field modeling code Hyrax
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Lin, Jun-li and Heuser, Brent J.
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- 2019
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10. Dissolution of Intermetallic Second-Phase Particles in Zircaloy-2 in High-Temperature Steam
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Zhong, Weicheng, Liu, Xiang, Mouche, Peter A., Lin, Jun-Li, Park, Donghee, Elbakhshwan, Mohamed S., Gill, Simerjeet K., Ren, Yang, Stubbins, James F., and Heuser, Brent J.
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- 2019
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11. Integration of a fused silica capillary and in-situ Raman spectroscopy for investigating CO2 solubility in n-dodecane at near-critical and supercritical conditions of CO2
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Jun-Liang Wang, Zi-Hao Song, Lin-Jun Li, Li-Li Yang, Quan-Yuan Wang, I-Ming Chou, and Zhi-Yan Pan
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Geophysics ,Fuel Technology ,Geochemistry and Petrology ,Energy Engineering and Power Technology ,Economic Geology ,Geology ,Geotechnical Engineering and Engineering Geology - Published
- 2022
12. Investigation on the influence of vortex generator on particle resuspension
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Yu, Dongchi, primary, Lin, Jun-Li, additional, and Xie, Jin-Han, additional
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- 2023
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13. Effect of external stress on deuteride (hydride) precipitation in Zircaloy-4 using in situ neutron diffraction
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Lin, Jun-li, An, Ke, Stoica, Alexandru D., and Heuser, Brent J.
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- 2017
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14. Study of the mechanical behavior of the hydride blister/rim structure in Zircaloy-4 using in-situ synchrotron X-ray diffraction
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Lin, Jun-li, Han, Xiaochun, Heuser, Brent J., and Almer, Jonathan D.
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- 2016
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15. In situ synchrotron tensile investigations on 14YWT, MA957, and 9-Cr ODS alloys
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Lin, Jun-Li, Mo, Kun, Yun, Di, Miao, Yinbin, Liu, Xiang, Zhao, Huijuan, Hoelzer, David T., Park, Jun-Sang, Almer, Jonathan, Zhang, Guangming, Zhou, Zhangjian, Stubbins, James F., and Yacout, Abdellatif M.
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- 2016
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16. Impact of delayed veno-venous extracorporeal membrane oxygenation weaning on postoperative rehabilitation of lung transplantation: a single-center comparative study
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Lin-Jun, Li, Hong-Yang, Xu, Xiao-Wen, Wang, Ke, Jin, Cheng, Zhang, Ming, Du, Jing-Yu, Chen, and Qing-Chen, Wu
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Biomaterials ,Biomedical Engineering ,Medicine (miscellaneous) ,Cardiology and Cardiovascular Medicine - Abstract
Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a reliable and effective extracorporeal life support during lung transplantation (LTx). However, the clinical benefit of delayed VV-ECMO weaning remains unclear. The current study aims to investigate whether delayed weaning of VV-ECMO is more beneficial to the rehabilitation for lung transplant patients. Patients who underwent LTx with VV-ECMO between January 2017 and January 2019 were included. Enrollment of patients was suitable for weaning off ECMO immediately after surgery. Randomization was performed in the operating room. Postoperative outcomes were compared between the two groups. Besides, univariate and multivariable logistic regressions were performed to estimate risk of postoperative complications. Compared to VV-ECMO weaning immediately after LTx, delayed weaning was associated with shorter hospital length of stay (days, 31 vs. 46; P 0.05), lower incidence of noninvasive ventilation (4.3% vs. 24.4%; P 0.05), primary graft dysfunction (PGD) (6.4% vs. 29.3%; P 0.05), atrial fibrillation (AF) (4.3% vs. 22%, P 0.05), and respiratory failure (4.3% vs. 19.5%; P 0.05). Multivariable logistic regressions revealed that VV-ECMO weaning after LTx was independently correlated with increased risk of developing PGD [odds ratio (OR), 5.97, 95% CI 1.16-30.74], AF (OR, 6.87, 95% CI 1.66-28.47) and respiratory failure (OR, 6.02, 95% CI 1.12-32.49) by comparison of delayed VV-ECMO weaning. Patients with delayed VV-ECMO weaning are associated with lower complications and short hospital length of stay, while it relates to longer mechanical ventilation. These findings suggest that delayed VV-ECMO after LTx can facilitate rehabilitation.
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- 2022
17. Impact Factors of COVID-19 Vaccination Hesitancy in patients after lung cancer surgery: an outpatients-based cross-sectional study (Preprint)
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Xiao-Wen Wang, Can Qu, Lin-Jun Li, Chun Huang, Dan Chen, and Qing-Chen Wu
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BACKGROUND The safety and efficacy of several vaccine candidates have been tested and found to be effective and safe against COVID-19. But little is known about the actual level of people with lung cancer willing to accept a COVID-19 vaccine and the impact factors that affect acceptability. OBJECTIVE The purpose of this study was to determine the prevalence of vaccine hesitancy in lung cancer patients after surgery and characterize underlying factors contributing to reluctance. METHODS An clinical survey was inducted from May 1, 2021, to August 20, 2021. Eligible participants were 18 years or older, were diagnosed with lung cancer, and received lung cancer surgery, including lobectomy, sublobectomy, and pneumonectomy. Data were collected on a self-administered questionnaire from 294 lung cancer patients after surgery. RESULTS Among the final included 281 participants, 54.1% were female, and 93.6% were of Han ethnicity. 48.0% were in pathologic stage I, 36.3% in stage II, 10.3% in stage III, and 5.3% in stage IV. The vaccination hesitancy/refusal rate was 41.6%. In multivariable regression analysis, age over 60 years old, low educational level, duration of cancer (< 1 year), subjective health status, current cancer treatments use, presence of postoperative pain, and report of the items “ever hesitated or refused to get a vaccination,” “get negative information about getting the COVID-19 vaccine”, “worried about vaccine adverse reactions,” and “worried about the COVID vaccine interferes with cancer treatments” were independently associated with hesitant of the COVID-19 vaccine. CONCLUSIONS Vaccine hesitancy is common among lung cancer patients after surgery, related mainly to health status and concerns about side effects, worsens cancer prognosis, and interferes with cancer treatments. These results suggest that vaccination programs may need tailoring to specific populations’ hesitancy.
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- 2022
18. Impact Factors of COVID-19 Vaccination Hesitancy in patients after lung cancer surgery: an outpatients-based cross-sectional study
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Can Qu, Si-Zhou Xiang, Lin-Jun Li, Xiao-Wen Wang, Chun Huang, Dan Chen, and Qing-Chen Wu
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Background The safety and efficacy of several vaccine candidates have been tested and found to be effective and safe against COVID-19. But, little is known about the actual level of people with lung cancer willing to accept a COVID-19 vaccine and the impact factors that affect acceptability. The survey aimed to determine the prevalence of vaccine hesitancy in lung cancer patients after surgery and characterize underlying factors contributing to reluctance. Methods An clinical survey was inducted from May 1, 2021, to August 20, 2021. Eligible participants were 18 years or older, were diagnosed with lung cancer, and received lung cancer surgery, including lobectomy, sublobectomy, and pneumonectomy. Data were collected on a self-administered questionnaire from 294 lung cancer patients after surgery. Results Among the final included 281 participants, 54.1% were female, and 93.6% were of Han ethnicity. 48.0% were in pathologic stage I, 36.3% in stage II, 10.3% in stage III, and 5.3% in stage IV. The vaccination hesitancy/refusal rate was 41.6%. In multivariable regression analysis, age over 60 years old, low educational level, duration of cancer (
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- 2022
19. Impact Factors of COVID-19 Vaccination Hesitancy in patients after lung cancer surgery: A outpatient-based cross-sectional study in Chongqing Cancer Center (Preprint)
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Xiao-Wen Wang, Can Qu, Lin-Jun Li, Chun Huang, Dan Chen, and Qing-Chen Wu
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Medicine (miscellaneous) ,Health Informatics - Published
- 2022
20. Uniportal video-assisted thoracic S9+10 segmentectomy using a single-direction approach is good for pulmonary function
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Xiao-Wen Wang, Lin-Jun Li, Chun Huan, Dan Chen, Ming Du, and Qing-Chen Wu
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Carbon Monoxide ,Lung Neoplasms ,Postoperative Complications ,Thoracic Surgery, Video-Assisted ,Carcinoma, Non-Small-Cell Lung ,Humans ,Surgery ,Pneumonectomy ,Retrospective Studies - Abstract
Uniportal video-assisted thoracic surgery is still a technical challenge, especially anatomical segmentectomy for the lateral basal segment (S9), posterior basal segment (S10), or both (S9+10). Different surgical procedures determine a variable pulmonary functional reduction depending on the extent of the resection. This study aimed to compare the efficiency of uniportal video-assisted thoracic surgery S9+10 segmentectomy with video-assisted thoracic surgery basal segmentectomy in preserving pulmonary function.The patients who had undergone single-port video-assisted thoracic surgery S9+10 segmentectomy using a single-direction approach were age, sex, and pulmonary function matched with those undergoing video-assisted thoracic surgery basal segmentectomy. The pulmonary function tests were performed preoperatively, and at 3 and 6 months postoperatively. The operative details, postoperative complications, and pulmonary function were statistically analyzed.After matching, a total of 46 patients undergoing video-assisted thoracic surgery S9+10 segmentectomy and 58 patients undergoing video-assisted thoracic surgery basal segmentectomy were eligible for analysis. There was no significant difference in the average blood loss, the duration of chest tube, intensive care unit stay, or hospital stay between these 2 groups. There were no major postoperative complications and surgical mortality was found in the 2 groups. The uniportal video-assisted thoracic surgery S9+10 segmentectomy group had a greater preserved pulmonary function (concerning the values of the forced vital capacity, forced expiratory volume in 1 second, forced expiratory volume in 1 second %, and diffusion capacity of carbon monoxide %) than video-assisted thoracic surgery basal segmentectomy group at 1 and 3 months postoperatively.Uniportal video-assisted thoracic surgery anatomic S9+10 segmentectomy using a single-direction approach was safe and feasible for early stages of nonsmall cell lung cancer, and it offered significantly better functional preservation compared with basal segmentectomy.
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- 2022
21. General Nexus Between Water and Electricity Use and Its Implication for Urban Agricultural Sustainability: A Case Study of Shenzhen, South China
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Wen-jiang LI, Lin-jun LI, and Guo-yu QIU
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water use per GDP ,electricity use per GDP ,industrial transformation ,Agriculture (General) ,S1-972 - Abstract
Although water and energy resources are well-recognized concerns regarding economic and social development sustainability, little specific research has focused on both water and energy problems at the same time. This study analyzed the water and electricity-use patterns in Shenzhen, South China during 2001-2009. A curve regression method was used to examine the relationship between water and electricity use per gross domestic product (GDP) in Shenzhen and its three sectors, i.e., agriculture, industry & construction, and residential life & services. Results showed that agriculture only covered less than 10% of water and electricity use in Shenzhen, while industry & construction and residential life & services accounted for more than 90% of water and electricity use in Shenzhen, which coincided with the city's industrial structure. The water and electricity use per GDP in agriculture was the biggest among three sectors in Shenzhen during 2001-2009, which means inefficiency of water and electricity use in agriculture. Due to transitioning to advanced materials and manufacturing, both water and electricity use per GDP in industry & construction decreased during 2001-2009 and their utilization efficiencies gradually increased over time. The same held true for those in residential life & services transformed toward modern business, creative culture, finance services, etc. Derived from the survival of the fittest in competing for limited water and electricity resources, agriculture in Shenzhen has been gradually substituted by industry & construction and residential life & services, with much higher efficiencies of water and electricity use. And traditional agriculture will not be sustainable in the process of urbanization and industrialization, except high-tech intensive agriculture with low water and energy cost. Furthermore, by means of curve regression, we found that there was a significant quadratic relationship between water use per GDP and electricity use per GDP in the entire city and its three sectors. Suitable industrial transformation and advancement was a very effective way to save water and energy for modern cities. This can provide some reference for systematic planning and design of water and electricity allocation and use in agriculture, industry & construction and residential life & services in a city.
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- 2013
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22. Refractory post-thymectomy myasthenia gravis with onset at MGFA stage V: a case report
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Rui-Qin Zhou, Lin-Jun Li, and Qing-Chen Wu
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Pulmonary and Respiratory Medicine ,Male ,Thymoma ,General Medicine ,Thymus Neoplasms ,Length of Stay ,Thymectomy ,Testicular Neoplasms ,Myasthenia Gravis ,Humans ,Surgery ,Cardiology and Cardiovascular Medicine ,Aged ,Retrospective Studies - Abstract
Background Post-thymectomy myasthenia gravis (PTMG) is defined as thymoma patients without signs of myasthenia gravis (MG) pre-operation, but develop MG after radical surgical resection. PTMG might be misdiagnosed not only because of its rare incidence, but also the uncertain interval between the removal of thymoma and the new onset MG. Additionally, some surgeons and anesthesiologists pay less attention to those asymptomatic thymoma patients in perioperative management, leading to the neglect of new onset PTMG, and miss the best time to treat it. Case presentation Majority of cases of PTMG with onset at stage I–II on the basis of Myasthenia Gravis Foundation of America (MGFA) classification have been reported, but rarely at stage V, which requiring intubation or non-invasive ventilation to avoid intubation. Herein, we presented a 70-year-old male with PTMG onset at MGFA stage V, meanwhile, he had severe pulmonary infection interfering with the diagnosis of PTMG, and eventually progressed to refractory PTMG, which requiring much more expensive treatments and longer hospital stays. Conclusion In the perioperative management of asymptomatic thymoma patients, careful preoperative evaluation including physical examination, electrophysiological test and acetylcholine receptor antibodies (AChR-Ab) level should be done to identify subclinical MG. Complete resection should be performed during thymectomy, if not, additional postoperative adjuvant therapy is neccessary to avoid recurrence. It’s important to identify PTMG at a early stage, especially when being interfered with by postoperative complications, such as lung infection, so that treatments could be initiated as soon as possible to avoid developing to refractory PTMG.
- Published
- 2021
23. Analysis of the application and practice of PDCA cycle in management of the naked medicine dispensing—the quality and safety of the drug
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Jia-Mei Zhu, Lin-Jun Li, Yun-Xiang Qiu, and Chun-Yan Zhao
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Drug ,business.industry ,media_common.quotation_subject ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,RT1-120 ,drug administration ,Nursing ,automatic medicine packing machine ,pdca cycle ,Education ,the naked medicine dispensing ,ComputerApplications_GENERAL ,Medicine ,Quality (business) ,Operations management ,business ,quality and safety ,PDCA ,General Nursing ,media_common - Abstract
Objective To explore the application of plan–do–check–action (PDCA) cycle in the management of the naked medicine dispensing about the automatic package and to analyze the practice improved in the quality of naked medicine dispensing medicine management. Methods The PDCA theory was used to analyze the data, to find out the causes of the problem, and to formulate the corresponding countermeasures to intervene. The data of the naked medicine/adverse drug events satisfaction degree of the inpatients in 18 inpatient departments given for the adoption of PDCA cycle in January 2017 were set as the observation group. The number of the naked medicine/adverse drug events satisfaction degree of patients in 18 inpatient departments before adoption of PDCA cycle in December 2016 was set as the control group. The number of the naked medicine/adverse drug events satisfaction degree of patients in 18 inpatient departments before and after adoption of PDCA cycle was observed and analyzed. Results The number of the naked medicine/adverse drug events after implementing the method of PDCA cycle management rate was significantly lower than before the implementation method of PDCA cycle management, and the difference had statistical significance (P < 0.05). The satisfaction degree of the inpatients after implementing the method of PDCA cycle management rate was significantly higher than that before the implementation method of PDCA cycle management, and the difference had statistical significance (P < 0.05). Conclusion Application of PDCA cycle in the management of the naked medicine dispensing about the automatic package can help to reduce the adverse drug events, to improve the safety of drug treatment, and to increase the patients’ satisfaction degree.
- Published
- 2019
24. Polybrominated diphenyl ethers (PBDEs) in dust in typical indoor public places in Hangzhou: Levels and an assessment of human exposure
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Xue You Shen, Dong Rui Wang, Yan Xia Zheng, Man Tong Jin, and Lin Jun Li
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Pollutant ,China ,Inhalation Exposure ,021110 strategic, defence & security studies ,Electronic markets ,Health, Toxicology and Mutagenesis ,0211 other engineering and technologies ,Public Health, Environmental and Occupational Health ,Dust ,02 engineering and technology ,General Medicine ,010501 environmental sciences ,Contamination ,01 natural sciences ,Pollution ,Human health ,Polybrominated diphenyl ethers ,Human exposure ,Air Pollution, Indoor ,Environmental chemistry ,Halogenated Diphenyl Ethers ,Humans ,Environmental science ,Environmental Monitoring ,0105 earth and related environmental sciences - Abstract
Polybrominated diphenyl ethers (PBDEs) are organic pollutants (POPs) with the characteristics of environmental persistence, long-distance transmission in nature, biological accumulation and toxic effects on human health. To investigate the level of contamination due to PBDEs in typical indoor public places in Hangzhou, dust samples were collected from ten supermarkets, three electronic markets and five different areas throughout one commodity market. Based on sample pretreatment and GC-ECD instrumental analysis, the contamination characteristics, sources and the influencing factors of 14 PBDE congeners were analyzed. The results revealed that the mean of ∑14PBDEs in dust in the supermarkets and electronic markets was 546.13 ng/g and 1140.05 ng/g, respectively, while in the commodity market the mean was 1005.42 ng/g and varied in the five different areas as follows: shoe areas (1367.22 ng/g) > parking lot (1001.05 ng/g) > waiting halls (970.31 ng/g) > packet areas (933.23 ng/g) > curtain areas (755.28 ng/g). The high levels of PBDE were attributed to the quantity of electrical appliances in the supermarkets (r = 0.708*, p
- Published
- 2019
25. PM2.5 and its ionic components at a roadside site in Wuhan, China
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Lin-Jun Li, Rong-Biao Xiang, and Wu Guang
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inorganic chemicals ,Atmospheric Science ,Chemistry ,Water soluble ions ,Ion chromatography ,Air pollution ,food and beverages ,chemistry.chemical_element ,Ionic bonding ,medicine.disease_cause ,Pollution ,Nitrogen ,Sulfur ,Ion ,Human exposure ,Environmental chemistry ,medicine ,Waste Management and Disposal - Abstract
PM2.5 samples were collected at a roadside site in Wuhan, China, for one year period. Ion chromatography was used to determine the water soluble ions in PM2.5 samples. Results showed that the overall average of PM2.5 mass was 118.1 ± 70.3 μg m−3, being slightly higher than those measured in urban sites in Wuhan, China. The major water soluble ions were NH4+ (8.7 ± 4.0 μg m−3), NO3− (12.1 ± 9.5 μg m−3), SO42− (15.2 ± 8.2 μg m−3), accounting for 21%、29%、37% of quantified total ions, respectively. NH4+, NO3−, and SO42− were closely correlated, and (NH4)2SO4 and NH4NO3 were possibly their main existing forms. Ion concentrations differed greatly in different seasons, with inconsistent variation pattern for individual ions. Values of NOR (nitrogen oxidation ratio) and SOR (sulfur oxidation ratio) peaked in winter and in summer, respectively. NO3−/SO42− ratio revealed that emission from stationary sources was still remarkable. Significant correlation was observed between Mg2+ and Ca2+, possibly due to their common source of soil dust. On the other hand, Cl− linked with K+, NO3−, NH4+, and SO42−. The data reported here will provide inputs for human exposure and air pollution control studies in Wuhan, China.
- Published
- 2019
26. Individualized model for predicting COVID-19 deterioration in patients with cancer: A multicenter retrospective study
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Xiao Rong Dong, Jie Wu, Liu Jing, Qi Bin Song, Yi Yao, Hong Yun Gong, Jiyuan Yang, Qian Chu, Ke Han Song, Zhi Guo Luo, Lin Jun Li, Zhibin Xie, Jie Wang, Lan Li, Xiu Li Luo, Zhi Guo Rao, Huibo Zhang, Qun Wang, Bin Xu, and Wei Dong Hu
- Subjects
0301 basic medicine ,Male ,Cancer Research ,medicine.medical_specialty ,China ,Coronavirus disease 2019 (COVID-19) ,retrospective study ,Disease ,Ground-glass opacity ,Decision Support Techniques ,03 medical and health sciences ,0302 clinical medicine ,risk model ,Risk Factors ,COVID‐19 ,Internal medicine ,Neoplasms ,medicine ,Humans ,cancer ,In patient ,Precision Medicine ,deterioration ,Aged ,Retrospective Studies ,Receiver operating characteristic ,business.industry ,Cancer ,COVID-19 ,Epidemiology and Prevention ,Retrospective cohort study ,General Medicine ,Original Articles ,Nomogram ,Middle Aged ,medicine.disease ,Survival Analysis ,Nomograms ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Area Under Curve ,Disease Progression ,Female ,Original Article ,medicine.symptom ,business - Abstract
The 2019 novel coronavirus has spread rapidly around the world. Cancer patients seem to be more susceptible to infection and disease deterioration, but the factors affecting the deterioration remain unclear. We aimed to develop an individualized model for prediction of coronavirus disease (COVID‐19) deterioration in cancer patients. The clinical data of 276 cancer patients diagnosed with COVID‐19 in 33 designated hospitals of Hubei, China from December 21, 2019 to March 18, 2020, were collected and randomly divided into a training and a validation cohort by a ratio of 2:1. Cox stepwise regression analysis was carried out to select prognostic factors. The prediction model was developed in the training cohort. The predictive accuracy of the model was quantified by C‐index and time‐dependent area under the receiver operating characteristic curve (t‐AUC). Internal validation was assessed by the validation cohort. Risk stratification based on the model was carried out. Decision curve analysis (DCA) were used to evaluate the clinical usefulness of the model. We found age, cancer type, computed tomography baseline image features (ground glass opacity and consolidation), laboratory findings (lymphocyte count, serum levels of C‐reactive protein, aspartate aminotransferase, direct bilirubin, urea, and d‐dimer) were significantly associated with symptomatic deterioration. The C‐index of the model was 0.755 in the training cohort and 0.779 in the validation cohort. The t‐AUC values were above 0.7 within 8 weeks both in the training and validation cohorts. Patients were divided into two risk groups based on the nomogram: low‐risk (total points ≤ 9.98) and high‐risk (total points > 9.98) group. The Kaplan‐Meier deterioration‐free survival of COVID‐19 curves presented significant discrimination between the two risk groups in both training and validation cohorts. The model indicated good clinical applicability by DCA curves. This study presents an individualized nomogram model to individually predict the possibility of symptomatic deterioration of COVID‐19 in patients with cancer., This is the first study to present a nomogram model to individually predict the deterioration of COVID‐19 in cancer patients. Clinical symptoms, computed tomography image features, cancer types, and comorbidities were incorporated in the model. Risk stratification was carried out targeting cancer populations for COVID‐19 deterioration. Cancer type was a critical factor affecting symptomatic deterioration. The COVID‐19 patients with lymphoma had the highest risk score for symptomatic deterioration.
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- 2021
27. Vof-16 knockout improves the recovery from hypoxic-ischemic brain damage of neonatal rats
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Jia Liu, Ruo-Lan Du, Lu-Lu Xue, Liu-Lin Xiong, Shuai-Jie Huang, Bao-Lei Zhang, Yan-Xin Tan, Lin-Jun Li, Zhang-Yu Su, Xi-Yang Yanbin, Tan, Yan Xin, Du, Ruo Lan, Su, Zhang Yu, Xue, Lu Lu, Liu, Jia, Zhang, Bao Lei, Huang, Shuai Jie, Li, Lin Jun, Xi-Yang, Yan Bin, and Xiong, Liu Lin
- Subjects
0301 basic medicine ,Knockout rat ,Encephalopathy ,non-coding RNA ,Morris water navigation task ,Hippocampus ,Brain damage ,Motor Activity ,Bioinformatics ,behavioural evaluations ,Open field ,Hypoxic Ischemic Encephalopathy ,Rats, Sprague-Dawley ,03 medical and health sciences ,Gene Knockout Techniques ,0302 clinical medicine ,Cortex (anatomy) ,medicine ,Animals ,hypoxic-ischemic encephalopathy ,Maze Learning ,Molecular Biology ,business.industry ,General Neuroscience ,Vof-16 knockout ,Brain ,Proteins ,Recovery of Function ,medicine.disease ,Rats ,030104 developmental biology ,medicine.anatomical_structure ,Animals, Newborn ,Hypoxia-Ischemia, Brain ,Neurology (clinical) ,medicine.symptom ,CRISPR-Cas Systems ,business ,030217 neurology & neurosurgery ,Developmental Biology - Abstract
Hypoxic-ischemic encephalopathy (HIE) results in high neonatal mortality and severe neurological impairments, and its underlying molecular mechanism underwent extensive investigations. Long non-coding RNA (lncRNA) is considered to be an important regulator on brain development and many neurological diseases. Currently, little is known about the role of Vof-16 (lncRNA) in HIE. We detected the relative expression level of Vof-16 in the cortex and hippocampus of hypoxic-ischemic (HI) models whose successful establishment was verified by TTC staining. Then, Vof-16 knockout rats were generated using the CRISPR/Cas engineering technology to search the specific function of the Vof-16 through a series of behavioral evaluations including Neurological severity scores (NSS), Y-maze test, Morris water maze (MWW) test, open field test, and Rotarod test. The results demonstrated the expression of Vof-16 was substantially up-regulated in the cortex and hippocampus of rats with HI injury. Importantly, Vof-16 knockout facilitated the recovery from long-term HI induced nerve damage and neurobehavioral dysfunctions. In conclusion, this study suggests Vof-16 knockout is a promising treatment target for neonatal HIE. Refereed/Peer-reviewed
- Published
- 2020
28. Double Q-switch Ho:Sc 2 SiO 5 laser by acousto-optic modulator combined with Cr 2+ :ZnSe saturable absorber
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Wen-qiang Xie, Lin-jun Li, Xiao-tao Yang, and Peng Zhang
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Materials science ,business.industry ,Slope efficiency ,Saturable absorption ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,law.invention ,010309 optics ,Optics ,law ,0103 physical sciences ,Acousto-optic modulator ,Optoelectronics ,M squared ,Electrical and Electronic Engineering ,0210 nano-technology ,business - Abstract
A double Q-switch (DQS) Ho:Sc 2 SiO 5 laser modulated by a acousto-optic modulators (AOM) combined with a Cr 2+ :ZnSe saturable absorber (SA) was reported for the first time. The actively Q-switch (AQS) and passively Q-switch (PQS) were also studied. For the DQS mode, a maximum average output power of 2.49 W under the incident pump power of 12.5 W was obtained, corresponding to a slope efficiency of 24%. The characteristics of the DQS Ho:SSO laser versus different repetition frequencies (RF) of the AOM were researched. The maximum single-pulse energy of the DQS Ho:SSO laser was calculated to 1.98 mJ. The maximum peak power of the DQS Ho:SSO laser was 49.5 kW. The output beam quality factor M 2 of DQS Ho:SSO laser was measured to be 1.15 with the highest peak power by knife-edge method at different positions.
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- 2018
29. Meta-analysis of the effects of oral and intravenous dexamethasone premedication in the prevention of paclitaxel-induced allergic reactions
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Fuchao Chen, Xiu-min Zhang, Lin-hai Wang, Lin-Jun Li, Xiao-yu Zheng, and Jun Zhang
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0301 basic medicine ,China ,medicine.medical_specialty ,Paclitaxel ,Premedication ,Anti-Inflammatory Agents ,Administration, Oral ,dexamethasone ,Pharmacy ,allergic reaction ,law.invention ,Drug Hypersensitivity ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Randomized controlled trial ,law ,Neoplasms ,Internal medicine ,Humans ,Medicine ,Dexamethasone ,business.industry ,Incidence (epidemiology) ,Antineoplastic Agents, Phytogenic ,Surgery ,meta-analysis ,Regimen ,030104 developmental biology ,Oncology ,chemistry ,030220 oncology & carcinogenesis ,Meta-analysis ,Injections, Intravenous ,business ,Research Paper ,medicine.drug - Abstract
// Fu-chao Chen 1 , Lin-hai Wang 2 , Xiao-yu Zheng 3 , Xiu-min Zhang 1 , Jun Zhang 4 , Lin-Jun Li 4 1 Department of Pharmacy, Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei, 442008, P.R. China 2 Department of Pharmacy, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, P.R. China 3 International School of Software, Wuhan University, Wuhan, Hubei, 430079, P.R. China 4 Department of Oncology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, P.R. China Correspondence to: Lin-Jun Li, email: rmyyllj@sina.com Keywords: paclitaxel, dexamethasone, allergic reaction, meta-analysis Received: September 14, 2016 Accepted: November 19, 2016 Published: November 29, 2016 ABSTRACT Background: Dexamethasone premedication is required to prevent paclitaxel-related hypersensitivity reactions (HSRs). Oral dexamethasone (PO-D) has been considered the standard premedication regimen. However, whether intravenous dexamethasone (IV-D) is feasible for preventing paclitaxel-related HSRs is still unclear. We conducted a meta-analysis to compare these two regimens. Methods: We performed a systematic search in the PubMed, China National Knowledge Infrastructure, and Web of Science databases for relevant articles published before June 2016. Outcomes included HSRs and severe HSRs. Statistical analyses were performed using RevMan 5.2 software. Result: Six studies comprising 1347 patients were included in the meta-analysis. The PO-D premedication regimen showed a significantly decreased incidence of severe HSRs compared with the IV-D regimen with an OR of 0.53 (95% CI 0.28-0.99, p = 0.05). However, there was no difference in the overall paclitaxel-related HSR rates between the two premedication regimens (OR 0.76, 95% CI 0.55-1.06, p = 0.11). Subgroup analyses according to study type and country of origin showed similar statistical results between the two premedication regimens. Conclusion: Our meta-analysis showed that the PO-D premedication regimen is superior to the IV-D regimen in preventing paclitaxel-related HSRs. Additional randomized controlled trials are needed to confirm our findings.
- Published
- 2016
30. Flux-creep activation energy for a BaFe1.9Ni0.1As2 single crystal derived from alternating current susceptibility measurements.
- Author
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Jun-Yi Ge, Lin-Jun Li, Zhu-An Xu, and Moshchalkov, Victor V.
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- *
SINGLE crystals , *ACTIVATION energy , *CURRENT density (Electromagnetism) , *OPTICAL vortices , *FLUX creep , *ALTERNATING current measurement - Abstract
Systematic acsusceptibilitymeasurements have been performed to investigate the vortex dynamics in a BaFe1.9Ni0.1As2 single crystal as a function of temperature, frequency, ac field amplitude, and dc magnetic field. The complex activation energyU(T,B,j) is derived in the framework of thermally activated flux creep theory and can be expressed in one simple formula. A power law dependence of U ~ Bα with α?=?-0.46 is observed. The activation energy reaches 104 K at low fields, suggesting strong pinning in the material. The nonlinear function of the activation energy vs. the current density is determined, which has the expression of U ∝j-0.1. [ABSTRACT FROM AUTHOR]
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- 2016
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31. Metformin therapy associated with survival benefit in lung cancer patients with diabetes
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Ping Chen, Xiaojun Cai, Guoxing Wan, Fengjun Cao, Xianhe Wang, Xiongjie Yu, Xuanbin Wang, Dongfeng Pan, and Lin-Jun Li
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0301 basic medicine ,Oncology ,medicine.medical_specialty ,Lung Neoplasms ,medicine.medical_treatment ,survival ,Diabetes Complications ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Internal medicine ,Diabetes Mellitus ,medicine ,Humans ,Hypoglycemic Agents ,Lung cancer ,Chemotherapy ,diabetes ,business.industry ,Hazard ratio ,medicine.disease ,Confidence interval ,Metformin ,Surgery ,meta-analysis ,lung cancer ,030104 developmental biology ,030220 oncology & carcinogenesis ,Meta-analysis ,Clinical Research Paper ,metformin ,business ,Chemoradiotherapy ,medicine.drug - Abstract
The purpose of this study is to summarize the currently available evidence regarding the concerned issue by performing a comprehensive meta-analysis. Relevant publications reporting the association of metformin use with survival of lung cancer patients with diabetes were electronically searched to identify eligible studies. The meta-analysis was performed with hazard ratios (HRs) and 95% confidence intervals (95% CIs) as effect measures for disease-free survival(DFS) and overall survival(OS) estimates. A total of 17 individual studies from 10 publications were included in the meta-analysis. Overall, the results revealed a significant association of metformin use with a better survival of lung cancer patients with diabetes(for DFS: HR = 0.65, 95%CI = 0.52-0.83; for OS: HR = 0.78, 95%CI = 0.64-0.93). The subgroup analyses showed similar association in Asian region(for DFS:HR = 0.69, 95%CI = 0.59-0.80; for OS: HR = 0.55, 95%CI = 0.46-0.67) but not in Western region. Such association was also presented in small cell lung cancer (for DFS: HR = 0.54, 95%CI = 0.38-0.77; for OS: HR = 0.52, 95%CI = 0.39-0.69) and in non-small cell lung cancer(for DFS: HR = 0.70, 95%CI = 0.51-0.96; for OS: HR = 0.75, 95%CI = 0.58- 0.97). Analyses stratified by treatment strategy showed a reduction in the risk of cancer-related mortality in patients receiving chemotherapy(for DFS: HR = 0.71, 95%CI = 0.64-0.83; for OS: HR = 0.58, 95%CI = 0.47-0.71) but not in patients receiving chemoradiotherapy. The meta-analysis demonstrated that metformin use was significantly associated with a favorable survival outcome of lung cancer patients with diabetes.
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- 2016
32. Direct measurement of hydrogen diffusivity and solubility limits in Zircaloy 2 (formula unit of ZrH0.0155) using incoherent quasi-elastic neutron scattering
- Author
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Heuser, Brent J., primary, Prisk, Timothy R., additional, Lin, Jun-li, additional, Dax, Tanya J., additional, and Zhang, Yongfeng, additional
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- 2019
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33. Effects of corticosteroids on new-onset atrial fibrillation after cardiac surgery: A meta-analysis of randomized controlled trials.
- Author
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Lu Liu, Fu-Yu Jing, Xiao-Wen Wang, Lin-Jun Li, Rui-Qin Zhou, Cheng Zhang, Qing-Chen Wu, Liu, Lu, Jing, Fu-Yu, Wang, Xiao-Wen, Li, Lin-Jun, Zhou, Rui-Qin, Zhang, Cheng, and Wu, Qing-Chen
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- 2021
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34. Study of X-cor Sandwich's Compression Modulus Based on Homogenization Theory
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Xudan Dang, Rui Zhang, Weimin Long, Shao-jie Shi, Jun Xiao, Bing-bing Fan, and Lin-jun Li
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Materials science ,Modulus ,Composite material ,Homogenization (chemistry) - Published
- 2017
35. The Measurement of Environmental Performance and Economic Performance Based on Catastrophe Theory: Case Studies of Thermal Power Industry and Steel Industry in China
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Su Li, Guoyu Qiu, Lin Jun Li, and Wen Jiang Li
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Pollution ,Engineering ,business.industry ,media_common.quotation_subject ,Environmental engineering ,Thermal power station ,General Medicine ,Environmental economics ,Correlation analysis ,Resource use ,Positive relationship ,Catastrophe theory ,China ,business ,media_common - Abstract
We employed catastrophe theory and entropy method to measure and compare the environmental performance and economic performance of 40 listed companies from the thermal power and steel industries in China, to explore their relationship. The results showed that the environmental performance of the steel industry was less than that of the thermal power industry, but their economic performance was similar. This means that steel industry has had lower resource use efficiency and more pollutant emission, and has a larger potential to saving resources, energy and environment pollution. Both the correlation analysis and regression analysis indicated that there existed a significant positive relationship between the environmental performance and economic performance of the steel industry and thermal power industry in China. This means that it is very possible to gain win-win situation of these two performances, if the listed companies tend to make advanced production and environment protection activities come into a benevolent cycle, by means of technology upgrading and transformation.
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- 2014
36. Small-angle neutron scattering measurements of δ-phase deuteride (hydride) precipitates in Zircaloy 4
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Heuser, Brent J., primary, Lin, Jun-Li, additional, Do, Changwoo, additional, and He, Lilin, additional
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- 2018
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37. Azimuthally anisotropic hydride lens structures in Zircaloy 4 nuclear fuel cladding: High-resolution neutron radiography imaging and BISON finite element analysis
- Author
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Lin, Jun-Li, primary, Zhong, Weicheng, additional, Bilheux, Hassina Z., additional, and Heuser, Brent J., additional
- Published
- 2017
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38. Large Scale Graphene/Hexagonal Boron Nitride Heterostructure for Tunable Plasmonics
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Kian Ping Loh, Lin Jun Li, Fung Ling Yap, Kai Zhang, Chang Tai Ng, and Kun Li
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Fabrication ,Materials science ,Graphene ,Gate dielectric ,Heterojunction ,Nanotechnology ,Chemical vapor deposition ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,Biomaterials ,law ,Monolayer ,Electrochemistry ,Wafer ,Plasmon - Abstract
Vertical integration of hexagonal boron nitride (h-BN) and graphene for the fabrication of vertical field-effect transistors or tunneling diodes has stimulated intense interest recently due to the enhanced performance offered by combining an ultrathin dielectric with a semi-metallic system. Wafer scale fabrication and processing of these heterostructures is needed to make large scale integrated circuitry. In this work, by using remote discharged, radio-frequency plasma chemical vapor deposition, wafer scale, high quality few layer h-BN films are successfully grown. By using few layer h-BN films as top gate dielectric material, the plasmon energy of graphene can be tuned by electrostatic doping. An array of graphene/h-BN vertically stacked micrometer-sized disks is fabricated by lithography and transfer techniques, and infrared spectroscopy is used to observe the modes of tunable graphene plasmonic absorption as a function of the repeating (G/h-BN)n units in the vertical stack. Interestingly, the plasmonic resonances can be tuned to higher frequencies with increasing layer thickness of the disks, showing that such vertical stacking provides a viable strategy to provide wide window tuning of the plasmons beyond the limitation of the monolayer.
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- 2013
39. Assessment of Air Quality Status in Wuhan, China
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Rong-Biao Xiang, Lin-Jun Li, Jiabei Song, and Wu Guang
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Pollution ,Atmospheric Science ,010504 meteorology & atmospheric sciences ,Meteorology ,media_common.quotation_subject ,010501 environmental sciences ,Environmental Science (miscellaneous) ,lcsh:QC851-999 ,01 natural sciences ,complex mixtures ,Air pollutants ,medicine ,China ,Air quality index ,0105 earth and related environmental sciences ,media_common ,Pollutant ,Seasonality ,medicine.disease ,air quality ,cluster analysis ,spatiotemporal variation ,respiratory tract diseases ,Environmental science ,lcsh:Meteorology. Climatology ,Physical geography - Abstract
In this study, air quality characteristics in Wuhan were assessed through descriptive statistics and Hierarchical Cluster Analysis (HCA). Results show that air quality has slightly improved over the recent years. While the NO2 concentration is still increasing, the PM10 concentration shows a clearly downward trend with some small fluctuations. In addition, the SO2 concentration has steadily decreased since 2008. Nevertheless, the current level of air pollutants is still quite high, with the PM10 and NO2 levels exceeding the air quality standard. Seasonal variation exists consistently for all the pollutants, with the highest concentration in winter and the lowest in summer. Cluster analysis evidenced that nine urban monitoring sites could be classified into three clusters. Cluster I consists of only the LY site, which is located in the famous East Lake scenic area with the best air quality. Cluster II corresponds to three monitoring sites with heavily trafficked roads nearby, where relatively severe NO2 pollution occurred. Cluster III is comprised of the remaining five sites, characterized by PM10 and SO2 pollution.
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- 2016
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40. System utility based resource allocation for multi-cell OFDM system
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Xiaofeng Tao, Xiao-dong Xu, Zhi-jie Hao, Lin-jun Li, Yinghong Zhao, and Zhongqi Zhang
- Subjects
Resource (project management) ,Operations research ,Computer Networks and Communications ,Risk aversion ,Orthogonal frequency-division multiplexing ,Computer science ,Signal Processing ,Resource allocation ,Customer satisfaction ,Mobile communication systems ,Multiplexing ,Information Systems - Abstract
Utility based resource allocation strategy in multi-cell orthogonal frequency-division multiplexing (OFDM) system plays a critical role in next generation mobile communication systems. Based on the analysis of risk aversion utility functions, this article proposed the system utility based utility, which is named the customer satisfaction (CS) utility. Compared with the proportional fairness (PF) utility, the CS utility reflects the user demands better, and enables the system to adjust its resource allocation according to both the traffic requirements and the resource situation.
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- 2010
41. Te Substitution Effect in Low-Dimensional Superconductor NbSe2-xTex (x = 0, 0.1, 0.2)
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Hong Tao Wang, Zhu-An Xu, Lin Jun Li, Cheng He, Jing Qin Shen, and Ejaz Ahmed
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Superconductivity ,Materials science ,Condensed matter physics ,Mechanical Engineering ,Substitution (logic) ,Doping ,Condensed Matter Physics ,Degree (temperature) ,Crystal ,Mechanics of Materials ,Superconducting transition temperature ,General Materials Science ,Substitution effect ,Critical field - Abstract
The Te doped NbSe2-xTex (x=0, 0.10, 0.20) single crystals were prepared by vapor transport method and the variations of structure and superconducting properties with Te content were studied. It is found that the Te substitution increases the degree of disorder and causes sharp decrease of superconducting transition temperature (Tc). The temperature dependence of upper critical field (Hc2) of pure NbSe2 crystal can be fitted by the two-band model, and the effect of Te substitution on Hc2(T) is discussed.
- Published
- 2007
42. Elevated red cell distribution width contributes to a poor prognosis in patients with esophageal carcinoma
- Author
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Fengjun Cao, Lin-Jun Li, Xiaojun Cai, Xiongjie Yu, Guoxing Wan, Xianhe Wang, Dongfeng Pan, Xuanbin Wang, and Ping Chen
- Subjects
Adult ,Erythrocyte Indices ,Male ,medicine.medical_specialty ,Poor prognosis ,Multivariate analysis ,Esophageal Neoplasms ,Clinical Biochemistry ,Kaplan-Meier Estimate ,Biochemistry ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Carcinoma ,Medicine ,Humans ,In patient ,Aged ,Retrospective Studies ,business.industry ,Proportional hazards model ,Biochemistry (medical) ,Cancer ,Retrospective cohort study ,Red blood cell distribution width ,General Medicine ,Middle Aged ,medicine.disease ,Prognosis ,Surgery ,030220 oncology & carcinogenesis ,Multivariate Analysis ,030211 gastroenterology & hepatology ,Female ,business - Abstract
The red cell distribution width (RDW) has also been reported to reliably reflect the inflammation and nutrition status and predict the prognosis across several types of cancer, however, the prognostic value of RDW in esophageal carcinoma has seldom been studied.A retrospective study was performed to assess the prognostic value of RDW in patients with esophageal carcinoma by the Kaplan-Meier analysis and multivariate Cox regression proportional hazard model. All enrolled patients were divided into high RDW group (≧15%) and low RDW group (15%) according to the detected RDW values.Clinical and laboratory data from a total of 179 patients with esophageal carcinoma were retrieved. With a median follow-up of 21months, the high RDW group exhibited a shorter disease-free survival (DFS) (p0.001) and an unfavorable overall survival (OS) (p0.001) in the univariate analysis. The multivariate analysis revealed that elevated RDW at diagnosis was an independent prognostic factor for shorter PFS (p=0.043, HR=1.907, 95% CI=1.020-3.565) and poor OS (p=0.042, HR=1.895, 95% CI=1.023-3.508) after adjustment with other cancer-related prognostic factors.The present study suggests that elevated preoperative RDW(≧15%) at the diagnosis may independently predict poorer disease-free and overall survival among patients with esophageal carcinoma.
- Published
- 2015
43. Compact intra-cavity pumped low-threshold passively Q-switched Ho:Sc2SiO5 laser by a LD-pumped Tm:YAP laser at room temperature
- Author
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Wen-qiang Xie, Long Liu, Lin-jun Li, and Xiao-tao Yang
- Subjects
Materials science ,Physics and Astronomy (miscellaneous) ,Laser diode ,business.industry ,Saturable absorption ,02 engineering and technology ,Laser ,01 natural sciences ,law.invention ,010309 optics ,Wavelength ,020210 optoelectronics & photonics ,law ,Optical cavity ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,Continuous wave ,Optoelectronics ,M squared ,business ,Instrumentation ,Pulse-width modulation - Abstract
A compact intra-cavity pumped low-threshold passively Q-switched (PQS) Ho:Sc2SiO5 (Ho:SSO) laser is reported for the first time. The Tm:YAlO3 (Tm:YAP) crystal and the Ho:SSO crystal are placed in the same laser cavity. A laser diode with a central wavelength of 793 nm is used to realize the output of the Ho:SSO laser. Both the continuous wave (CW) and PQS operation are investigated. A Cr2+:ZnSe is used as the saturable absorber in the PQS Ho:SSO laser. For the CW mode, the laser threshold is only 750 mW, which is 980 mW in the PQS mode. A maximum pulse energy of 699 µJ is primarily obtained, corresponding to the pulse width of 96 ns. The maximum repetition frequency is 1.46 kHz. The maximum pulse peak power can be calculated to be 7.28 kW. The beam quality factor M 2 is calculated to be 1.4 with the maximum output power.
- Published
- 2017
44. [Comparison of long-term health-related quality of life in patients with different methods of reconstruction after oncologic esophagectomy]
- Author
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Lin-jun, Li, Qing-chen, Wu, Cheng, Zhang, Min, Zhang, Li, Qiang, Ying-jiu, Jiang, and Dan, Chen
- Subjects
Adult ,Esophagectomy ,Male ,Esophageal Neoplasms ,Surveys and Questionnaires ,Quality of Life ,Humans ,Female ,Middle Aged ,Plastic Surgery Procedures ,Aged - Abstract
To explore the effects of reconstructing method (narrow gastric tube (NGT) versus whole stomach (WS)) on health-related quality of life (HRQL) in patients during a 3-year follow-up.In a prospective randomized single-center study from 2007 to 2008, 104 patients underwent esophagectomy for cancer. They were divided into NGT (n = 52) and WS (n = 52) groups. To assess HRQL, a questionnaire in references to EORTC-QLQ-C30 and QLQ-OES18 was administered at 3 weeks, 6 months, 1 year, 2 year and 3 years post-operation. Their clinical data were collected prospectively and follow-up was performed regularly.The patients in the NGT group reported significantly (P0.05) better average scores of HRQL at both 6 months and 1 year.However, no significant difference in average scores of HRQL was found at 3 years. Patients in the NGT group reported significantly (P0.05) better scores of reflux at 3 weeks, 6 months and 1 year.Nausea was the only item with significant difference on HRQL at 2 years and 3 years.No significant difference existed between two groups with regards to cumulative survival rate at 3 years.No significant difference existed between two groups with regards to cumulative survival rate at 3 years. The patients with gastric tube reconstruction after oncologic esophagectomy present better HRQL.Further studies are warranted to perform survival analysis beyond 3 year post-operation.
- Published
- 2013
45. Advances in research of the artificial cultivation of Ophiocordyceps sinensis in China
- Author
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Xuanwei Zhou, En-Wei Tian, and Lin-Jun Li
- Subjects
Cordyceps ,geography ,China ,geography.geographical_feature_category ,Resource (biology) ,biology ,Ecology ,Research ,Ophiocordyceps sinensis ,General Medicine ,Moths ,biology.organism_classification ,Applied Microbiology and Biotechnology ,Grassland ,Host-Parasite Interactions ,Industrial Microbiology ,Larva ,Animals ,Artificial feeding ,Medicine, Chinese Traditional ,Biotechnology - Abstract
Ophiocordyceps sinensis (syn. Cordyceps sinensis), a traditional Chinese medicine called DongChongXiaCao (DCXC) in Chinese, is well known and has been used in Asia countries since the fifteenth century, and it contains some valuable medicinal component defined by modern pharmacological science. DCXC only appears at high altitudes on the Qinghai-Tibetan Plateau. Consequently, it is difficult to find and harvest. Because of its rarity and medicinal value, DCXC has always been one of the most expensive medicines known. As the price of DCXC has risen in recent years, thousands of migrants have entered into the various grasslands to search for them in season, which makes ecological environments of the grassland more fragile. In order to relieve the environmental pressures and protect this valuable resource, the artificial cultivation of DCXC involving two aspects of the genus Hepialus and the fungi of the host larvae should be employed and applied at the first available time point. In this article, the reproduction of moth larvae of the genus Hepialus is first described, which includes their ecological characteristics and the methods of artificial feeding. Second, the generation and isolation method of the fungi from DCXC are subsequently summarized, and then the mechanism of fungal spores to attack the moth larvae are restated. Finally, the basic model of artificial cultivation of DCXC is introduced; meanwhile, the potential application of modern biotechnology to the artificial cultivation is analyzed in prospect. This review article will not only expand people's knowledge regarding the artificial cultivation of DCXC, but also hopefully provide an informative reference for the development of this valuable resource and the environmental protection of alpine meadows.
- Published
- 2013
46. Flux-creep activation energy for a BaFe1.9Ni0.1As2 single crystal derived from alternating current susceptibility measurements
- Author
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Jun-Yi Ge, Victor Moshchalkov, Lin-Jun Li, and Zhu-An Xu
- Subjects
Flux pinning ,Materials science ,Condensed matter physics ,General Physics and Astronomy ,02 engineering and technology ,Activation energy ,021001 nanoscience & nanotechnology ,01 natural sciences ,Power law ,Magnetic field ,Amplitude ,0103 physical sciences ,010306 general physics ,0210 nano-technology ,Type-II superconductor ,Current density ,Single crystal - Abstract
© 2016 Author(s). Systematic ac susceptibility measurements have been performed to investigate the vortex dynamics in a BaFe1.9Ni0.1As2 single crystal as a function of temperature, frequency, ac field amplitude, and dc magnetic field. The complex activation energy U (T, B, j) is derived in the framework of thermally activated flux creep theory and can be expressed in one simple formula. A power law dependence of U ∼ B α with α = -0.46 is observed. The activation energy reaches 104K at low fields, suggesting strong pinning in the material. The nonlinear function of the activation energy vs. the current density is determined, which has the expression of U ∝ j-0.1. ispartof: Journal of Applied Physics vol:119 issue:16 status: published
- Published
- 2016
47. Te Substitution Effect in Low-Dimensional Superconductor NbSe2-xTex (x = 0, 0.1, 0.2)
- Author
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Ejaz Ahmed, Lin Jun Li, Cheng He, Hong Tao Wang, Jing Qin Shen, and Zhuan Xu
- Published
- 2007
48. [Preparation and stability investigation of gastrodin dispersible tablets]
- Author
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Yan-wei, Xi, Gui-hua, Huang, and Lin-jun, Li
- Subjects
Plants, Medicinal ,Drug Stability ,Glucosides ,Solubility ,Area Under Curve ,Chemistry, Pharmaceutical ,Pharmaceutic Aids ,Technology, Pharmaceutical ,Lactose ,Benzyl Alcohols ,Drugs, Chinese Herbal ,Tablets - Abstract
To prepare and optimize the gastrodin dispersible tablets by orthogonal design using the disintegration time as index. The quality of gastrodin dispersible tablets was evaluated by the initial stability test. The results showed that the disintegration time of optimized prescription formulation was 106s, i.e. L-HPC and CMS-Na was used by combining exterior and interior and the dissolution percent in vitro was obviously super to the conventional tablets. Moreover, the quality of the dispersible tablets was very well by stability test.
- Published
- 2007
49. Hierarchical Structures: Large Scale Graphene/Hexagonal Boron Nitride Heterostructure for Tunable Plasmonics (Adv. Funct. Mater. 6/2014)
- Author
-
Kai Zhang, Chang Tai Ng, Kun Li, Fung Ling Yap, Lin Jun Li, and Kian Ping Loh
- Subjects
Biomaterials ,Materials science ,Scale (ratio) ,Graphene ,law ,Electrochemistry ,Hexagonal boron nitride ,Nanotechnology ,Heterojunction ,Condensed Matter Physics ,Plasmon ,Electronic, Optical and Magnetic Materials ,law.invention - Published
- 2014
50. Mechanical Characteristics of PVA/STMP Hydrogel in Tensile and Unconfined Compression
- Author
-
Zhu, Wei, primary, Gao, Jin, additional, Li, Xiao Gang, additional, Lin, Jun Li, additional, Cao, Han Hui, additional, and Sun, Bai Tian, additional
- Published
- 2012
- Full Text
- View/download PDF
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