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Objective Based on 3D printing technology, explore the precision of a perforator vessel location guide plate for fibular musculocutaneous flaps before the transplantation of fibular osteocutaneous flaps and evaluate its application effects. Methods This study was reviewed and approved by the ethics committee, and informed consent was obtained from the patients. From May 2019 to October 2022, 14 patients with jaw defects who needed to undergo fibular perforator flap transplantation at the First Affiliated Hospital of Xinjiang Medical University were selected. For the seven patients in the guide plate group, CTA was combined with Mimics software to reconstruct both lower limbs, and the perforator vessel positioning guide for locating perforator vessels was designed; the two ends of the guide plate were designed as fixed ends, with the upper end fixed to the knee joint and the lower end fixed to the ankle joint, and the guide plate was fabricated by a 3D printer. For the seven patients in the control group, a conventional handheld Doppler probe was used for perforator vessel location. The average operation time, bleeding volume, recovery time, deviation of perforator vessel location, postoperative flap-related complications, postoperative donor site shape satisfaction, and lower extremity functional scale (LEFS) score were recorded. SPSS 25.0 software was used for statistical analysis. Results The average operation time, bleeding volume, recovery time, deviation of perforator vessel location and postoperative donor site shape satisfaction were significantly better in the guide plate group than in the control group (P0.05). Conclusion Based on 3D printing technology, fibular musculocutaneous flap perforator vessels can be more accurately located using a guide plate and the knee and ankle as fixed points, and this method can effectively stabilize the guide position, prevent soft tissue offset, and improve positioning accuracy and thus deserves to be generalized.

Cyclooxygenase 2 (COX2) can promote the synthesis of prostaglandins through metabolism, and is highly expressed in various tumor tissues including ovarian cancer. It can affect the occurrence and development of tumors in different ways by regulating downstream metabolites. It stimulates tumor cell proliferation and migration, promotes angiogenesis, inhibits apoptosis, plays an important role in tumor progression and may provide new ideas for tumor therapy.

The overall aim of the current paper is to establish best practices for developing, engaging and working critically in virtual intercultural communication. The need to build practical language communication skills is not a new idea or a new part of methodology. With the development of technology, the range of communicative opportunities has grown and allowed virtual intercultural dialogues to take place. The focus of these situations is not only language development and practice, but also critical cultural awareness and intercultural skill development. The paper presents contrasting approaches in the methodological construction of one such programme between young students in Entel Foreign Language School, China, and Krosno State College, Poland. Over the course of the link from Spring to Summer 2017, different approaches were taken by the instructors and students in both countries resulting in varying levels of engagement and critical understanding. The Chinese approach stresses communication as an outcome and delivers more time to oral activities in the classroom, which contrasts with the Polish approach of a stricter language-based teaching strategy. As a result, the paper will discuss the relative merits of the two methodological frameworks in the communication project. This will be achieved by evaluating the overall success of the communication based on interviews with the student participants and observations of interaction during the link meetings. Finally, the paper will illustrate a methodology for working with such links and developing intercultural communication.

Author(s): Yutong Liu [sup.1] [sup.2] , Bin Ling [sup.1] , Dusheng Chen [sup.3] Author Affiliations: (1) https://ror.org/01wd4xt90, grid.257065.3, 0000 0004 1760 3465, Business School, Hohai University, , 8 Focheng West [...], Career adaptability is a psychological resource for individuals to deal with career events, and it is a system of human-environment interaction. The components of the career adaptability concept are not independent of each other but rather an interactive network. The present study aims to shed light on the nomological network of career adaptability and the starting salary by investigating their indicators using network analysis to reveal their structural networks and interrelationships. In addition, we compared the similarities and differences between the networks of different gender groups. Results indicate that career adaptability directly connects to starting salary for graduates, and some indicators are the core factors that influence starting salary. Besides, the global structure of gender-specific networks is very similar. However, some differences have been detected, such as becoming curious about new opportunities is the male network's core, while the core of the female network is doing the right thing.