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2. Synthesis of a mixed valence state Ce-MOF as an oxidase mimetic for the colorimetric detection of biothiols

Author

Shulin Zhao, Siheng Chen, Shufen Shen, Cong Zhang, Yuhao Xiong, Lingjing Su, and Fanggui Ye

Subjects
Oxidase test, Valence (chemistry), Chemistry, Metals and Alloys, General Chemistry, Cerium, Photochemistry, Serum samples, Combinatorial chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Materials Chemistry, Ceramics and Composites, Organometallic Compounds, Humans, Colorimetry, Partial oxidation, Sulfhydryl Compounds
Abstract

We demonstrate a facile and rapid in situ partial oxidation synthetic strategy for the fabrication of a mixed valence state Ce-MOF (MVCM) which exhibits intrinsic oxidase-like activity. Furthermore, on the basis of the excellent catalytic activity of the MCVM, a colorimetric approach for the high-throughput detection of biothiols in serum samples was established.

Published
2015

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