35 results on '"Linney, Ian D."'
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2. Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
3. Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases
4. Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β2 agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD)
5. Achiral, selective CCK 2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
6. Inhibitors of immuno-oncology target HPK1 – a patent review (2016 to 2020)
7. Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
8. An enzymatic approach to the desymmetrization of disubstituted pyrrolines
9. Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases
10. Erratum to “Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template” [Bioorg. Med. Chem. 16 (2008) 2974–2983]
11. Flexible Strategy for the Synthesis of Pyrrolizidine Alkaloids
12. Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
13. Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists
14. Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion
15. Novel, Achiral 1,3,4-Benzotriazepine Analogues of 1,4-Benzodiazepine-Based CCK2 Antagonists That Display High Selectivity over CCK1 Receptors
16. Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists
17. Synthesis of Enantiopure Dihydropyranones: Aldol-Based Ring Expansion of Dihydrofurans
18. Partial Reduction of Annulated Heterocycles as a General Route to Medium Rings Containing Oxygen and Nitrogen
19. ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationships of Novel Non-Imidazole Histamine H3 Receptor Antagonists.
20. 2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a New Template for the Design of CCK2 Receptor Antagonists
21. Design, Synthesis, and Structure−Activity Relationships of Novel Non-Imidazole Histamine H3 Receptor Antagonists
22. A Convenient Synthesis of N-Alkyl-(E)-1-alkenesulfonamides
23. Recoverable chiral sulfoxides for asymmetric synthesis: application to stereoselective carbonyl reduction and the asymmetric synthesis of allylic alcohols
24. The asymmetric synthesis of allylic alcohols using a recoverable chiral sulphoxide
25. The total synthesis of epibatidine
26. Recoverable chiral sulfoxides for asymmetric synthesis: preparation, regeneration and application to the asymmetric aldol reaction
27. A new class of recoverable chiral sulphoxide: Application to the asymmetric synthesis of β-hydroxy esters.
28. Chiral Recognition Reactions of Homochiral Sulphinate Esters: A Study of the Reaction Between the Enolate, and the Anion of the Corresponding Dimethylhydrazone, Derived from 4-tert-Butylcyclohexanone and (1R,2S,5R)-(-)-Menthyl-(S)-p-Tolylsulphinate
29. Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases
30. Erratum to “Achiral, selective CCK 2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template” [Bioorg. Med. Chem. 16 (2008) 2974–2983]
31. ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationships of Novel Non-Imidazole Histamine H3 Receptor Antagonists.
32. ChemInform Abstract: Design, Synthesis, and Structure—Activity Relationships of Novel Non‐Imidazole Histamine H3Receptor Antagonists.
33. Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
34. Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β 2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
35. Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β 2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
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