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3. Development of Kudzu (Pueraria Montana var. lobata) Reference Materials for the Determination of Isoflavones and Toxic Elements

Author

Lippert, J Andreas, primary, Rimmer, Catherine A, additional, Phillips, Melissa M, additional, Nelson, Michael A, additional, Barber, Charles A, additional, Wood, Laura J, additional, Long, Stephen E, additional, Bryan, Colleen E, additional, Sharpless, Katherine E, additional, Yen, James, additional, Kuszak, Adam J, additional, and Wise, Stephen A, additional

Published
2022
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25. Evaluation of Superfund Removal Action at the King Edward Mine.

Author

Lippert, J. Andreas, Davidson, Charles F., Davidson, Robert A., and Schaffer, Tori L.

Subjects
*URANIUM mining, *WATER pollution, *DRINKING water, COMPREHENSIVE Environmental Response, Compensation & Liability Act of 1980 (U.S.)
Abstract

Thousands of abandoned uranium mines are located in the Four Corners Area from mining occurring between the 1940s and 1970s. The abandoned King Edward Mine, located on Manti-La Sal National Forest land, was the object of a Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Removal Action in 2009 because of both environmental and safety issues, which included discharge of water contaminated with radionuclides and metals, eroding waste rock piles, and open adits. This study evaluated the effectiveness of the Superfund removal action at the King Edward Mine. Water samples from the remediated site were analyzed for arsenic, cadmium, lead, selenium, and uranium using inductively coupled plasma-mass spectrometry (ICP-MS). Samples from the mine adits substantially exceeded the elemental concentration limits for drinking water set by the Environmental Protection Agency (EPA). Samples taken from the stream above and below the mine had concentrations lower than the EPA drinking water regulations for four of the elements studied. Uranium concentrations from the samples taken upstream and downstream were higher than EPA drinking water regulations, but they were not statistically different. Therefore, there was no evidence of additional seepage coming from the mine into the stream at the time of this study. [ABSTRACT FROM AUTHOR]

Published
2021

29. AOAC SMPR® 2017.011

Author

Zielinski, Garrett, primary, Atkinson, Gisele, additional, Bhandari, Sneh D., additional, Burns, Paul, additional, Citrolo, Danielle, additional, Farthing, Christine, additional, Glover, Brandi, additional, Horkey, Adam, additional, Johnson, Holly E., additional, Kuszak, Adam, additional, Lin, Jeff, additional, Lippert, J. Andreas, additional, Mudge, Elizabeth, additional, Ofitserova, Maria, additional, Reimann, Lars M., additional, Solyom, Aniko M., additional, Sullivan, Darryl M., additional, Szpylka, John, additional, Travis, John, additional, Wubben, Jason Lynn, additional, Yang, Jinchuan, additional, You, Hong, additional, Young, Kurt, additional, and Coates, Scott G., additional

Published
2017
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30. AOAC SMPR® 2017.013:Standard Method Performance Requirements (SMPRs) for Determination of Vitamins K1 and K2 in Dietary Supplements and Dietary Ingredients

Author

Reidun, Inger, primary, Atkinson, Gisele, additional, Bhandari, Sneh, additional, Craft, Neal, additional, Horkey, Adam, additional, Kuszak, Adam, additional, Lippert, J Andreas, additional, Mudge, Elizabeth, additional, Rimmer, Kate, additional, Solyom, Aniko, additional, Sommer, William, additional, Szpylka, John, additional, Wubben, Jason, additional, Yang, Jinchuan, additional, and You, Hong, additional

Published
2017
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33. Trade in live reptiles, its impact on wild populations, and the role of the European market

Author

Auliya, M, Altherr, S, Ariano-Sanchez, D, Baard, EH, Brown, C, Brown, RM, Cantu, JC, Gentile, G, Gildenhuys, P, Henningheim, E, Hintzmann, J, Kanari, K, Krvavac, M, Lettink, M, Lippert, J, Luiselli, L, Nilson, G, Quang Nguyen, T, Nijman, V, Parham, JF, Pasachnik, SA, Pedrono, M, Rauhaus, A, Rueda Cordova, D, Sanchez, ME, Schepp, U, van Schingen, M, Schneeweiss, N, Segniagbeto, GH, Somaweera, R, Sy, EY, Turkozan, O, Vinke, S, Vinke, T, Vyas, R, Williamson, S, Ziegler, T, Auliya, M, Altherr, S, Ariano-Sanchez, D, Baard, EH, Brown, C, Brown, RM, Cantu, JC, Gentile, G, Gildenhuys, P, Henningheim, E, Hintzmann, J, Kanari, K, Krvavac, M, Lettink, M, Lippert, J, Luiselli, L, Nilson, G, Quang Nguyen, T, Nijman, V, Parham, JF, Pasachnik, SA, Pedrono, M, Rauhaus, A, Rueda Cordova, D, Sanchez, ME, Schepp, U, van Schingen, M, Schneeweiss, N, Segniagbeto, GH, Somaweera, R, Sy, EY, Turkozan, O, Vinke, S, Vinke, T, Vyas, R, Williamson, S, and Ziegler, T

Abstract

Of the 10,272 currently recognized reptile species, the trade of fewer than 8% are regulated by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) and the European Wildlife Trade Regulations (EWTR). However, the International Union for Conservation of Nature (IUCN) Red List has assessed 45% of the world's reptile species and determined that at least 1390 species are threatened by “biological resource use”. Of these, 355 species are intentionally targeted by collectors, including 194 non-CITES-listed species. Herein we review the global reptile pet trade, its impacts, and its contribution to the over-harvesting of species and populations, in light of current international law. Findings are based on an examination of relevant professional observations, online sources, and literature (e.g., applicable policies, taxonomy [reptile database], trade statistics [EUROSTAT], and conservation status [IUCN Red List]). Case studies are presented from the following countries and regions: Australia, Central America, China, Galapagos Islands (Ecuador), Germany, Europe, India, Indonesia (Kalimantan), Islamic Republic of Iran, Japan, Madagascar, Mexico, New Zealand, the Philippines, South Africa, Sri Lanka, Vietnam, Western Africa, and Western Asia. The European Union (EU) plays a major role in reptile trade. Between 2004 and 2014 (the period under study), the EU member states officially reported the import of 20,788,747 live reptiles. This review suggests that illegal trade activities involve species regulated under CITES, as well as species that are not CITES-regulated but nationally protected in their country of origin and often openly offered for sale in the EU. Further, these case studies demonstrate that regulations and enforcement in several countries are inadequate to prevent the overexploitation of species and to halt illegal trade activities.

Published
2016

34. Trade in live reptiles, its impact on wild populations, and the role of the European market

Author

Auliya, Mark, Altherr, S., Ariano-Sanchez, D., Baard, E.H., Brown, C., Brown, R.M., Cantu, J.-C., Gentile, G., Gildenhuys, P., Henningheim, E., Hintzmann, J., Kanari, K., Krvavac, M., Lettink, M., Lippert, J., Luiselli, L., Nilson, G., Nguyen, T.Q., Nijman, V., Parham, J.F., Pasachnik, S.A., Pedrono, M., Rauhaus, A., Córdova, D.R., Sanchez, M.-E., Schepp, U., van Schingen, M., Schneeweiss, N., Segniagbeto, G.H., Somaweera, R., Sy, E.Y., Türkozan, O., Vinke, S., Vinke, T., Vyas, R., Williamson, S., Ziegler, T., Auliya, Mark, Altherr, S., Ariano-Sanchez, D., Baard, E.H., Brown, C., Brown, R.M., Cantu, J.-C., Gentile, G., Gildenhuys, P., Henningheim, E., Hintzmann, J., Kanari, K., Krvavac, M., Lettink, M., Lippert, J., Luiselli, L., Nilson, G., Nguyen, T.Q., Nijman, V., Parham, J.F., Pasachnik, S.A., Pedrono, M., Rauhaus, A., Córdova, D.R., Sanchez, M.-E., Schepp, U., van Schingen, M., Schneeweiss, N., Segniagbeto, G.H., Somaweera, R., Sy, E.Y., Türkozan, O., Vinke, S., Vinke, T., Vyas, R., Williamson, S., and Ziegler, T.

Abstract

Of the 10,272 currently recognized reptile species, the trade of fewer than 8% are regulated by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) and the European Wildlife Trade Regulations (EWTR). However, the International Union for Conservation of Nature (IUCN) Red List has assessed 45% of the world's reptile species and determined that at least 1390 species are threatened by “biological resource use”. Of these, 355 species are intentionally targeted by collectors, including 194 non-CITES-listed species. Herein we review the global reptile pet trade, its impacts, and its contribution to the over-harvesting of species and populations, in light of current international law. Findings are based on an examination of relevant professional observations, online sources, and literature (e.g., applicable policies, taxonomy [reptile database], trade statistics [EUROSTAT], and conservation status [IUCN Red List]). Case studies are presented from the following countries and regions: Australia, Central America, China, Galapagos Islands (Ecuador), Germany, Europe, India, Indonesia (Kalimantan), Islamic Republic of Iran, Japan, Madagascar, Mexico, New Zealand, the Philippines, South Africa, Sri Lanka, Vietnam, Western Africa, and Western Asia. The European Union (EU) plays a major role in reptile trade. Between 2004 and 2014 (the period under study), the EU member states officially reported the import of 20,788,747 live reptiles. This review suggests that illegal trade activities involve species regulated under CITES, as well as species that are not CITES-regulated but nationally protected in their country of origin and often openly offered for sale in the EU. Further, these case studies demonstrate that regulations and enforcement in several countries are inadequate to prevent the overexploitation of species and to halt illegal trade activities.

Published
2016

38. Solutions for biomedical grid computing - Case studies from the D-Grid project Services@MediGRID

Author

Dickmann, F., Falkner, J., Gunia, W., Hampe, J., Hausmann, M., Herrmann, A., Kepper, N., Knoch, T.A., Lauterbach, S., Lippert, J., Peter, K., Schmitt, E., Schwardmann, U., Solodenko, J., Sommerfeld, D., Steinke, T., Weisbecker, A., Sax, U., and Publica

Abstract

The project Services@MediGRID consortium established a tool set of grid-based biomedical services since 2008. The services are related to genetic analysis, genome data visualization, and pharmacokinetic modeling. Furthermore, business concepts for these services have been examined which are supported by an accounting and billing service. While the tools cover a whole service chain for biomedicine, the business concepts are rather heterogeneous. However, the overall addressed target market areas show promising potential. In addition, a structured coaching process reduces friction in the technology transfer from grid computing to biomedicine. This should be considered for similar future endeavors.

Published
2012

45. Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation.

Author

Marshall, SF, Burghaus, R, Cosson, V, Cheung, SYA, Chenel, M, DellaPasqua, O, Frey, N, Hamrén, B, Harnisch, L, Ivanow, F, Kerbusch, T, Lippert, J, Milligan, PA, Rohou, S, Staab, A, Steimer, JL, Tornøe, C, and Visser, SAG

Subjects
DRUG design, DRUG development, PHARMACEUTICAL industry, RESEARCH & development, MEDICAL decision making
Abstract

This document was developed to enable greater consistency in the practice, application, and documentation of Model-Informed Drug Discovery and Development (MID3) across the pharmaceutical industry. A collection of 'good practice' recommendations are assembled here in order to minimize the heterogeneity in both the quality and content of MID3 implementation and documentation. The three major objectives of this white paper are to: i) inform company decision makers how the strategic integration of MID3 can benefit R&D efficiency; ii) provide MID3 analysts with sufficient material to enhance the planning, rigor, and consistency of the application of MID3; and iii) provide regulatory authorities with substrate to develop MID3 related and/or MID3 enabled guidelines. [ABSTRACT FROM AUTHOR]

Published
2016
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50. Die oberen Atemwege im Speziesvergleich

Author

Reinhold, P., primary, Grützenmacher, S., additional, Pabst, R., additional, Koch, R., additional, Schulz, R., additional, Kirschvink, N., additional, Oechtering, G., additional, Lippert, J., additional, Fey, K., additional, and Rosenbruch, M., additional

Published
2010
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