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Cytokinesis in budding yeast involves an actomyosin-based ring which assembles in a multistepped fashion during the cell cycle and constricts during cytokinesis. In this report, we have investigated the structural and regulatory events that occur at the onset of cytokinesis. The septins, which form an hour-glass like structure during early stages of the cell cycle, undergo dynamic rearrangements prior to cell division: the hourglass structure splits into two separate rings. The contractile ring, localized between the septin double rings, immediately undergoes contraction. Septin ring splitting is independent of actomyosin ring contraction as it still occurs in mutants where contraction fails. We hypothesize that septin ring splitting may remove a structural barrier for actomyosin ring to contract. Because the Tem1 small GTPase (Tem1p) is required for the completion of mitosis, we investigated its role in regulating septin and actomyosin ring dynamics in the background of the net1-1 mutation, which bypasses the anaphase cell cycle arrest in Tem1-deficient cells. We show that Tem1p plays a specific role in cytokinesis in addition to its function in cell cycle progression. Tem1p is not required for the assembly of the actomyosin ring but controls actomyosin and septin dynamics during cytokinesis.

A letter is presented from John Lippincott, President of the Council for Advancement & Support of Education (CASE), before his retirement to his successor at the position, sharing his experiences at the organization and offering advice to manage the organization.

A personal narrative is presented which explores the author's experience on riding his bike.

The author reflects on the global advancement of educational institutions. He stresses that the spread of a certain language and the gifts of donations to establish educational institutions signifies growth in educational philanthropy. The author suggests that the climate for the advancement of educational institutions could improve by fostering professional standards and best practices, as well as advocating public policies which will aid to achieve the aim for growth.

The article discusses the goals of American nonprofit association of educational institutions Council for Advancement and Support of Education (CASE) which serves professionals in the field of educational advancement. It mentions the challenges faced by educational advancement including language and public misperception as the fields of alumni and public relations, fundraising and marketing are poorly understood. It states that the group also interacts millions of alumni, donors and students.

The author comments on the warning of the editor of the periodical "Inside Higher Ed" editor Scott Jaschik on the lack of concerns of universities and colleges on their wealth in the U.S. The author mentions that Jaschik complained that Harvard University is unworthy of support from philanthropist because it is subsidized by taxpayers. He states that the public should learn to listen and to reflect before responding to stories and views about compensation packages of universities.

The author reflects on the introduction of massive open online courses (MOOCs) within the education community over traditional classroom experiences. He mentions that MOOCs may help the graduates to sharpen their existing and develop new skills and to increase their options in a challenging employment marketplace. He also states that with the invention of MOOCs, colleges and universities are able too re-engage alumni in the intellectual life of the institution.

The article reports on the proposal of the White House and the U.S. congressional leaders which states that donors can claims for charitable contributions by reduction in income tax deduction. It discusses five myths regarding the limits on the charitable tax deduction focusing on tax policy, unfair means of tax deduction. It also mentions that the Council of Administrators of Special Education (CASE) along with several other charitable organizations has opposed the proposals.

The article focuses on leadership changes in universities and colleges. It includes information on the reason behind leadership transition that occurs due to the condition of tenure of school, college and university leaders. It includes information on the role advancement officer in handling leadership change which includes planning a smooth leadership transition, reinforcing of brands and position of institutions and setting priorities.

The author discusses the culture of the Council for Advancement and Support of Education (CASE) in the U.S. and the factors that distinguishes the CASE culture from other associations. He highlights how the CASE staff and volunteers recognize the importance of service to its member institutions and professionals for improvement and advancement. He also notes the organization's culture of collegiality, integrity, and quality that contribute to the fulfillment of their mission, vision, and values.

The author discusses the political correctness for advancement colleagues to discuss the governance, institutional values, and political policies. The author mentions that the use of institutions by election candidates for political advertising may misinterpret or abuse by candidates but any opportunity given to one candidate should be also given to all candidates. He states that establishing staff policy on political activity is essential to restrict staff members for supporting candidates.

In this article, the author discusses how to strengthen the ethical practice. He argues that importance of adopting principles of practice for the advancement disciplines such as conflict of interest, fundraiser compensation, and donor rights. He suggests reviewing established policies and testing the policies against real-world scenarios taken from recent experience and headlines. He notes that playing out scenarios may expose conflicts between personal and institutional value systems.

An introduction is presented in which the editor discusses various reports within the issue on topics including honors professionals, field of advancement, and honor student leaders.

The article discusses the issues concerning the influence of tax benefits towards donor behavior. It states that major donors are spending their money wisely and they want to be wise with their philanthropy. Moreover, it notes that the influence of tax incentives is accepted by historical data on donation in the U.S.

In this article, the author discusses the list of 10 mistakes in fundraising and communications for alumni relations. It mentions the undervaluing of alumni relations as the stepchild of advancement instead of vital success of educational institution. Thus, alumni undervaluing often lead to underestimation of the profession which is likely the largest sources of philanthropic support. Consequently, the underestimation of an institution underutilizes its strategic goals in quality education.

The article offers information concerning the top ten mistakes that lead to the failure to communicate. It mentions that one of such mistakes include trying to please everyone, an energy-draining method wherein one's limited time resources can impair the organization if tolerated. It also mentions other factors involving ineffective communication such as assuming, hoping for headlines and ignoring one's self.

The article focuses on the awards programs and scholarships of Council for Advancement and Support of Education (CASE). It discusses the features of CASE's awards programs including its inclusion of individuals and member institutions with recognition for accomplishments. It adds that the awards are decided by panels of colleagues, who understand the opportunities, challenges, and rewards in the profession. Also, it invites qualified individuals and institutions to join its awards programs.

In this article the author discusses the mistakes involved in educational fundraising. The author states that most institutions failed to recognize their fundraising potential, wherein they overlooked to invest in hiring and retaining frontline fundraisers. He emphasizes on the failure to identify the most significant form of engagement, which is also the most important thing for the donor. He adds that it is considered a worst mistake to think that the sole intention of fundraising is money.

The article focuses on the why, what, and how of the research activity of the Council for Advancement and Support of Education (CASE). It states that the research agenda is driven by three practical goals in service of its members and educational advancement including performance improvement, outcomes illumination, and decision making dissemination. It stresses that the research is centered on best practice and common practice. It also says that CASE conducts primary and secondary research.

In this article, the author discusses regarding educational advancement. He is critical on the impact of online world in education in which it provides powerful tools that are helpful in various educational undertakings such as research, outreach and stewardship. Also cited is the emergence of the internationalization of the educational marketplace which resulted to intensified global competition for reputation and resources. It also adds the influence of global economic crisis in education.

The article focuses on the advocacy efforts of the Council for Advancement and Support of Education (CASE) for the advancement profession in the U.S. and Europe. It states that CASE's advocacy for advancement cites the legislative proposals harmful to the work including alumni credit cards restrictions, endowment payout mandates, and donor privacy challenges. It poses the importance of the advocacy to obtain success in the professional field.

The article reports on the strategies that need to be considered by the Council for Advancement and Support of Education (CASE which will help them address the impact of the global recession. These include building relationship with alumni and enhancing fundraising activities, improving public relations and asking support from universities. He stresses that the strategies will promote professional development and improve operations by institutions.

The author reflects on the significance of endowments for college students in the U.S. He mentions that endowments are an important part of education quality and donors give to endowments because they believe in the institution's mission. He points out that the majority of funds held in endowments are restricted for purposes specified by the donor. Moreover, he asserts that endowment payout rates have little connection to tuition rates which are influenced by increasing costs.