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Abstract Employees in enterprises face numerous challenges due to the severe employment situation and job pressure. Sales personnel and research and development (R&D) personnel in companies are particularly susceptible to mental health issues due to the unique nature and complexity of their work. This study aims to explore the psychological health issues among sales personnel and R&D personnel in high-tech enterprises. Twenty-four R&D personnel (23 males and 1 female) and twenty-six sales personnel (25 males and 1 female) were recruited. The participants’ psychological health conditions were assessed using the Symptom Checklist-90 (SCL-90) and verbal fluency tasks combined with functional near-infrared spectroscopy (VFT-fNIRS), while their work stress level was evaluated using the Personal Stress Questionnaire (PSQ) and Personal Resources Questionnaire (PRQ). The results indicated significantly higher brain activities in the right dorsolateral prefrontal cortex and bilateral Broca’s areas of the R&D group compared to the sales group. The R&D group had significantly lower scores in the total score and multiple dimensions of SCL-90, such as somatization, obsession-compulsion, depression, anxiety, hostility, and paranoia. In addition, the R&D group exhibited significantly lower psychological and physical tension reactions compared to the sales group in PSQ. Based on the PRQ, the R&D group obtained significantly higher scores in self-care compared to the sales group. In conclusion, the mental health status of the R&D group is better than that of the sales group, the difference in self-care may be the most important factor leading to the difference in work stress and mental health of the two groups, VFT-fNIRS might be used to assist in detecting the mental health status of employees.

Abstract Background Remimazolam tosilate (RT) is a novel short-acting GABA (A) receptor agonist that has a rapid recovery from procedural sedation and can be fully reversed by flumazenil. To date, there have been relatively few articles comparing RT and propofol for general anesthesia. This study aimed to assess the efficacy and safety of RT with or without flumazenil compared with propofol in general anesthesia for day surgery. Methods 115 patients scheduled for day surgery were randomized into three groups: RT (n = 39), RT + flumazenil (n = 38) and propofol (n = 38). The primary endpoints were anesthesia induction time and time until fully alert. Anesthesia success rate, bispectral index (BIS) values, injection pain, opioid and vasopressor dosages, postoperative recovery profiles and perioperative inflammatory and cognitive changes were assessed. Any adverse events were recorded. Results Induction times were similar among the three groups (P = 0.437), but the median time until fully alert in patients treated with RT was longer than that of the propofol or RT + flumazenil groups (17.6 min vs. 12.3 min vs. 12.3 min, P 0.05). Smaller percentages of patients who received RT (26.3%) and RT + flumazenil (31.6%) developed hypotension during anesthesia maintenance compared with propofol (68.4%), and consequently less ephedrine (P

Abstract Online education is important in the COVID-19 pandemic, but online exam at individual homes invites students to cheat in various ways, especially collusion. While physical proctoring is impossible during social distancing, online proctoring is costly, compromises privacy, and can lead to prevailing collusion. Here we develop an optimization-based anti-collusion approach for distanced online testing (DOT) by minimizing the collusion gain, which can be coupled with other techniques for cheating prevention. With prior knowledge of student competences, our DOT technology optimizes sequences of questions and assigns them to students in synchronized time slots, reducing the collusion gain by 2–3 orders of magnitude relative to the conventional exam in which students receive their common questions simultaneously. Our DOT theory allows control of the collusion gain to a sufficiently low level. Our recent final exam in the DOT format has been successful, as evidenced by statistical tests and a post-exam survey.