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2. Evaluating Passivhaus EnerPHit retrofit strategies for low-rise suburban dwellings in China's hot summer-cold winter climate region

Author

Liu, Chenfei

Abstract

China is the largest energy consumer in the world, and the biggest source of energy demand in China is the building sector, which accounts for 46.5% of the country's total energy consumption and 51.3% of carbon emissions. The area with the fastest growth in building energy demand in the country is the central southern hot summer - cold winter climate region. The Passivhaus standard (and its retrofit equivalent EnerPHit) focusses on achieving ultra-low operational energy consumption. However, examples of Passivhaus and EnerPHit buildings are rare for hot climates, and this particularly true for China. When improving the energy performance of an existing building, it is also important to consider the environmental impact of any retrofit building materials that are used as part of an EnerPHit retrofitting programme. Therefore, this study investigated the energy savings, carbon emission reductions and cost savings that might accrue from retrofitting, to the EnerPHit standard, a case study dwelling located in China's hot summer - cold winter climate region. External weather and indoor thermal conditions of the case building were monitored for 12 months, and these data were used to validate a digital model of the dwelling. The model was used to evaluate retrofitting to the EnerPHit standard, which gave energy savings of 90.1% for heating and 72.6% for cooling compared with the pre-retrofit condition. Next, different combinations of retrofitting measures were evaluated for four different build scenarios to find how the EnerPHit criteria could be met using fewer building materials. Lastly, the finalized retrofitting plans for the case building were evaluated from the carbon and cost points of view, through detailed life cycle carbon and cost assessments. The results showed that the carbon payback time of the proposed retrofitting plans was much faster than the cost payback time, and that at the end of the evaluated lifespan, savings of up to 83.4% of the carbon emissions and 18% of the costs could be achieved.

Published
2022
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8. Development of Novel Paclitaxel-Loaded ZIF-8 Metal-Organic Framework Nanoparticles Modified with Peptide Dimers and an Evaluation of Its Inhibitory Effect against Prostate Cancer Cells

Author

Zhao, Heming, primary, Gong, Liming, additional, Wu, Hao, additional, Liu, Chao, additional, Liu, Yanhong, additional, Xiao, Congcong, additional, Liu, Chenfei, additional, Chen, Liqing, additional, Jin, Mingji, additional, Gao, Zhonggao, additional, Guan, Youyan, additional, and Huang, Wei, additional

Published
2023
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17. A chemical biology approach reveals a dependency of glioblastoma on biotin distribution

Author

Yoon, Jeehyun, primary, Grinchuk, Oleg V., additional, Kannan, Srinivasaraghavan, additional, Ang, Melgious Jin Yan, additional, Li, Zhenglin, additional, Tay, Emmy Xue Yun, additional, Lok, Ker Zhing, additional, Lee, Bernice Woon Li, additional, Chuah, You Heng, additional, Chia, Kimberly, additional, Tirado Magallanes, Roberto, additional, Liu, Chenfei, additional, Zhao, Haonan, additional, Hor, Jin Hui, additional, Lim, Jhin Jieh, additional, Benoukraf, Touati, additional, Toh, Tan Boon, additional, Chow, Edward Kai-Hua, additional, Kovalik, Jean-Paul, additional, Ching, Jianhong, additional, Ng, Shi-Yan, additional, Koh, Ming Joo, additional, Liu, Xiaogang, additional, Verma, Chandra Shekhar, additional, and Ong, Derrick Sek Tong, additional

Published
2021
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23. Evaluating Passivhaus EnerPHit Retrofit Strategies for Low-Rise Suburban Dwellings in China's Hot Summer - Cold Winter Climate Region

Author

Liu, Chenfei, Sharples, Steve, and Mohammadpourkarbasi, Haniyeh

Abstract

China is the largest energy consumer in the world, and the biggest source of energy demand in China is the building sector, which accounts for 46.5% of the country's total energy consumption and 51.3% of carbon emissions. The area with the fastest growth in building energy demand in the country is the central southern hot summer - cold winter climate region. The Passivhaus standard (and its retrofit equivalent EnerPHit) focusses on achieving ultra-low operational energy consumption. However, examples of Passivhaus and EnerPHit buildings are rare for hot climates, and this particularly true for China. When improving the energy performance of an existing building, it is also important to consider the environmental impact of any retrofit building materials that are used as part of an EnerPHit retrofitting programme. Therefore, this study investigated the energy savings, carbon emission reductions and cost savings that might accrue from retrofitting, to the EnerPHit standard, a case study dwelling located in China’s hot summer - cold winter climate region. External weather and indoor thermal conditions of the case building were monitored for 12 months, and these data were used to validate a digital model of the dwelling. The model was used to evaluate retrofitting to the EnerPHit standard, which gave energy savings of 90.1% for heating and 72.6% for cooling compared with the pre-retrofit condition. Next, different combinations of retrofitting measures were evaluated for four different build scenarios to find how the EnerPHit criteria could be met using fewer building materials. Lastly, the finalized retrofitting plans for the case building were evaluated from the carbon and cost points of view, through detailed life cycle carbon and cost assessments. The results showed that the carbon payback time of the proposed retrofitting plans was much faster than the cost payback time, and that at the end of the evaluated lifespan, savings of up to 83.4% of the carbon emissions and 18% of the costs could be achieved.

25. Correlation Between the Peripheral Neuropathy and Levels of hs-CRP, IL-1β and IL-6 in Senile Parkinson's Disease Patients.

Author

Zhang Y, Liu Y, Li Y, Zhang S, Yuan X, Liu C, Geng L, and Gu P

Subjects
Humans, C-Reactive Protein metabolism, Interleukin-1beta, Interleukin-6, Parkinson Disease, Peripheral Nervous System Diseases
Abstract

This study was carried out to investigate the correlation between the onset of peripheral neuropathy and levels of hypersensitive C-reactive protein (hs-CRP), interleukin 1β (IL-1β) and IL-6 in senile Parkinson's disease (PD) patients. For this purpose, a total of 60 PD patients and 60 age-matched healthy subjects were enrolled in this study and received the assessment for peripheral nerves by using the quantified method. Besides, levels of hs-CRP, IL-1β and IL-6 in serum were determined to analyze the correlation between the clinical features, including the severity of PD and cognitive decline, and the levels of hs-CRP, IL-1β and IL-6. Results showed that PD patients had more cases of peripheral neuropathy than those in the healthy control group. Levels of hs-CRP, IL-1β and IL-6 in the serum of PD patients were much higher than those in the healthy control (P<0.05). Besides, PD patients had lower scores of MMSE and MoCA but higher CNPI scores when compared to the healthy control group. As a result, we found that the severity of peripheral neuropathy was in a positive correlation with the levels of hs-CRP, IL-1β and IL-6. It was concluded that PD patients generally have peripheral neuropathy that may correlate with the increases in the levels of hs-CRP, IL-1β and IL-6, and early intervention may mitigate the development and progression of peripheral neuropathy.

Published
2023
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