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538 results on '"Liu, Dequan"'

20. Engineering design of the CFETR machine

Author

Song, Yuntao, Li, Jiangang, Wan, Yuanxi, Liu, Yong, Wang, Xiaolin, Wan, Baonian, Fu, Peng, Weng, Peide, Wu, Songtao, Duan, Xuru, Yang, Qingwei, Feng, Kaiming, Li, Qiang, Ye, Mingyou, Zhuang, Ge, Liang, Yunfeng, Gao, Xiang, Chen, Changan, Wang, Heyi, Zheng, Guoyao, Xu, Yuhong, Qian, Tianlin, Chan, Vincent, Xiao, Bingjia, Lu, Kun, Zheng, Jinxing, Lu, Mingxuan, Liu, Dequan, Liu, Jian, Wu, Yu, Liu, Xufeng, Shi, Yi, Hou, Binglin, Liu, Chen, Ge, Jian, Zhou, Caipin, Ran, Hong, Wang, Qijie, Wang, Xiaoyu, Liu, Songlin, Liu, Sumei, Yao, Damao, Cheng, Yong, Hu, Liqun, Hu, Chundong, Liu, Fukun, and Chen, Gen

Published
2022
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24. Advanced cobalt-based hierarchical and gradient armor catalysts for high-performance Li–S batteries over a wide temperature range.

Author

Li, Yiding, Wang, Siqi, Fu, Yujun, Li, Ruoan, Guo, Han, Lv, Chengtian, Yin, Xiaoqiang, Yang, Zhibo, Liu, Dequan, and He, Deyan

Abstract

Developing efficient and long-lasting cathode catalysts is crucial for preparing high-performance lithium–sulfur (Li–S) batteries. Here, we designed and synthesized hierarchical, gradient, and multi-dimensional Co@NCNN armor catalysts by pyrolyzing g-C3N4 in the presence of cobalt nitrate. The unique structure of the Co@NCNN armor catalysts combines 0D Co nanoparticles and outer carbon protective shells, which adsorb and confine LiPSs, as well as 1D carbon nanotubes and 2D carbon nanosheets, which enhance the sulfur load and block LiPS diffusion, respectively. XANES and XPS analysis showed that Co–Co bonds with different Co valence states are the main catalytic sites for LiPSs. In situ XRD experiments and Li2S deposition tests demonstrated that the Co@NCNN armor catalysts can accelerate the liquid–solid conversion process, resulting in an initial discharge capacity of 1388.9 mA h g−1 at 0.5 C, an excellent area capacity of 5.05 mA h cm−2 and a sulfur load of 6.1 mg cm−2. More importantly, the robust carbon layer protects the highly active inner cobalt nanoparticles, enabling them to perform 1000 cycles at a current density of 7 C, with a capacity decay rate of 0.048% per cycle, and maintain stability over a wide temperature range of 0 to 60 °C. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Advancements and Challenges in Peptide-Based Cancer Vaccination: A Multidisciplinary Perspective.

Author

Liu, Dequan, Liu, Lei, Li, Xinghan, Wang, Shijin, Wu, Guangzhen, and Che, Xiangyu

Subjects
CANCER vaccines, ADVERSE health care events, VACCINE effectiveness, PEPTIDES, RESEARCH personnel
Abstract

With the continuous advancements in tumor immunotherapy, researchers are actively exploring new treatment methods. Peptide therapeutic cancer vaccines have garnered significant attention for their potential in improving patient outcomes. Despite its potential, only a single peptide-based cancer vaccine has been approved by the U.S. Food and Drug Administration (FDA). A comprehensive understanding of the underlying mechanisms and current development status is crucial for advancing these vaccines. This review provides an in-depth analysis of the production principles and therapeutic mechanisms of peptide-based cancer vaccines, highlights the commonly used peptide-based cancer vaccines, and examines the synergistic effects of combining these vaccines with immunotherapy, targeted therapy, radiotherapy, and chemotherapy. While some studies have yielded suboptimal results, the potential of combination therapies remains substantial. Additionally, we addressed the management and adverse events associated with peptide-based cancer vaccines, noting their relatively higher safety profile compared to traditional radiotherapy and chemotherapy. Lastly, we also discussed the roles of adjuvants and targeted delivery systems in enhancing vaccine efficacy. In conclusion, this review comprehensively outlines the current landscape of peptide-based cancer vaccination and underscores its potential as a pivotal immunotherapy approach. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Single‐cell transcriptome sequencing of B‐cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy

Author

Wang, Qing, primary, Sun, Ke, additional, Liu, Rui, additional, Song, Ying, additional, Lv, Yafeng, additional, Bi, Pingping, additional, Yang, Fuying, additional, Li, Sijia, additional, Zhao, Jiawen, additional, Li, Xiuqin, additional, Chen, Dong, additional, Mei, Jialin, additional, Yang, Rirong, additional, Chen, Kai, additional, Liu, Dequan, additional, and Tang, Shichong, additional

Published
2023
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