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337 results on '"Liu, Dianfeng"'

17. Spatial Heterogeneity Analysis of the Multidimensional Characteristics of Urban Green Spaces in China—A Study Based on 285 Prefecture-Level Cities.

Author

Zhao, Wei, Liu, Dianfeng, Niu, Jiqiang, He, Jianhua, and Xu, Feng

Subjects
ECOLOGICAL zones, CITIES & towns, URBAN growth, SOCIAL services, ZONING, PUBLIC spaces
Abstract

Quantitative measurement of urban green spaces (UGSs) plays a fundamental role in enhancing their ecological functions and services. Current studies have not adequately analyzed the multifunctional characteristics and the diverse benefits of urban green spaces at the national scale. This study developed a multidimensional indicator system in terms of scale, pattern, and services to measure green spaces in 285 prefecture-level cities in China. The influences of different geographic zones and urban development on UGS characteristics were also investigated. The results showed that per capita area of urban green spaces were significantly different between the two sides of the "Botai Line", and the UGS structure was mainly dominated by woodlands. Urban green spaces in the central and east had higher fragmentation, lower landscape diversity, and weaker connectivity. The spatial accessibility of green spaces exhibited a "low–high–medium" pattern from north to south in China, with central-eastern China experiencing the worst equity in green space supply. Overall, cities with higher integrated benefits of green spaces were mainly located in Northeast and North China. Type I large cities had higher ratings for UGS characteristics compared with the other types of cities. These findings can serve as solid guidance for cities seeking to build green space systems with highly integrated socio–ecological benefits. [ABSTRACT FROM AUTHOR]

Published
2024
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18. The Use of the Multi-objective Ant Colony Optimization Algorithm in Land Consolidation Project Site Selection

Author

Wang, Hua, Li, Weiwei, Niu, Jiqiang, Liu, Dianfeng, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Sun, Xingming, editor, and Wang, Jinwei, editor

Published
2020
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32. Understanding coupled coordination relationships between social and ecological functions of urban green spaces.

Author

Liu, Dianfeng, Li, Huiying, Qiu, Mingli, and Liu, Yaolin

Subjects
SPACE, SOCIAL skills, CITIES & towns, URBAN growth, PUBLIC spaces, HABITAT conservation, ECOSYSTEM services, COMMUNITY life
Abstract

Urban Green Spaces (UGSs) can provide social and ecological benefits, and the coordination of these two functions will largely advance human-nature harmony in cities. As such, we proposed a comprehensive framework to evaluate UGSs multifunctionality, i.e. the coupling coordination relationship of ecological connectivity and spatial accessibility of UGSs. Wuhan City in Central China was taken as a case study, and multiple ecosystem service values of green space patches and the disordered use of UGSs multifunctionality were explored. The results demonstrated low-level coupling coordination of UGSs multifunctionality in Wuhan. More than 70% of UGSs were imbalanced, 27.91% of which featured small sizes, low connectivity and accessibility. We suggest that planners should optimize UGSs arrangement to improve species reachability, especially for species with dispersal distance less than 4 km, and to create 15-minute community life circles for residents at the same time. Our findings are expected to support the promotion of UGSs multifunctionality and the balance of urban development and habitat conservation. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Echinocystic Acid Inhibits Inflammation and Exerts Neuroprotective Effects in MPTP-Induced Parkinson’s Disease Model Mice

Author

He, Dewei, Hu, Guiqiu, Zhou, Ang, Liu, Yanting, Huang, Bingxu, Su, Yingchun, Wang, Hefei, Ye, Bojian, He, Yuan, Gao, Xiyu, Fu, Shoupeng, and Liu, Dianfeng

Subjects
NF-κB/MAPK, Pharmacology, echinostic acid, Parkinson’s disease, microglia, Pharmacology (medical), Therapeutics. Pharmacology, RM1-950, Original Research, neuroinflammation
Abstract

Parkinson’s disease (PD), the second primary neurodegenerative disease affecting human health, is mainly characterized by dopaminergic neuron damage in the midbrain and the clinical manifestation of movement disorders. Studies have shown that neuroinflammation plays an important role in the progression of PD. Excessively activated microglia produce several pro-inflammatory mediators, leading to damage to the surrounding neurons and finally inducing neurodegeneration. Echinocystic acid (EA) exhibits an anti-inflammatory effect in peripheral tissues. However, whether it inhibited neuroinflammation remains unclear. Therefore, the current study investigates the effect of EA on neuroinflammation and whether it can improve PD symptoms through inhibiting neuroinflammation. In our experiments, we discovered that EA inhibited the production of pro-inflammatory mediators in LPS-exposed BV2 cells. Further mechanism-related studies revealed that EA inhibited inflammation by activating PI3K/Akt and inhibiting NF-κB and MAPK signal pathways in LPS-induced BV2 cells. Research revealed that EA eases microglia-mediated neuron death in SN4741 and SHSY5Y cells. In in vivo studies, the results demonstrated that EA improves weight loss and behavioral impairment in MPTP-induced mice. Further studies have revealed that EA inhibited dopaminergic neuron damage and inflammation in the mice midbrain. In conclusion, our study demonstrated that EA inhibits neuroinflammation and exerts neuroprotective effects by activating PI3K/Akt and inhibiting NF-κB and MAPK signal pathways in vivo and in vitro.

Published
2022

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