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21 results on '"Liu, Min-Chao"'

5. Magnetic Co(II) Porphyrin Nanospheres Appending Different Substituent Groups Showing Higher Catalytic Activities in Cyclohexane

Author

Liu Min‐Chao, Chen Jiong, Zheng Min, MA Yan‐Na, Lin Jia‐qi, Tang Ding‐tong, Zhao Ping, Jin Shu‐fang, and Liu Hong‐Jian

Subjects
Cyclohexane, Biomedical Engineering, Substituent, Bioengineering, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Photochemistry, 01 natural sciences, Porphyrin, 0104 chemical sciences, Catalysis, chemistry.chemical_compound, chemistry, Polymer chemistry, General Materials Science, 0210 nano-technology
Published
2016

15. Calcium carbonate end-capped, folate-mediated Fe3O4@mSiO2 core-shell nanocarriers as targeted controlled-release drug delivery system.

Author

Liu, Min-Chao, Liu, Bing, Chen, Xian-Li, Lin, Hui-Chao, Sun, Xiang-Yu, Lu, Jia-Zheng, Li, Yan-Yu, Yan, Si-Qi, Zhang, Lu-Yong, and Zhao, Ping

Subjects
*CALCIUM carbonate, *MAGNETISM, *FOURIER transform spectroscopy, *ZETA potential, *FOLIC acid
Abstract

Magnetic mesoporous silica nanospheres (MMSN) were prepared and the surface was modified with cancer cell-specific ligand folic acid. Calcium carbonate was then employed as acid-activated gatekeepers to cap the mesopores of the MMSN, namely, MMSN-FA-CaCO3. The formation of the MMSN-FA-CaCO3 was proved by several characterization techniques, viz. transmission electron microscopy, zeta potential measurement, Fourier transform infrared spectroscopy, BET surface area measurement, and UV–Vis spectroscopy. Daunomycin was successfully loaded in the MMSN-FA-CaCO3 and the system exhibited sensitive pH stimuli-responsive release characteristics under blood or tumor microenvironment. Cellular uptake by folate receptor (FR)-overexpressing HeLa cells of the MMSN-FA-CaCO3 was higher than that by non-folated-conjugated ones. Intracellular-uptake studies revealed preferential uptake of these nanoparticles into FR-positive [FR(+)] HeLa than FR-negative [FR(-)]A549 cell lines. DAPI stain experiment showed high apoptotic rate of MMSN-FA-DNM-CaCO3 to HeLa cells. The present data suggest that the CaCO3 coating and folic acid modification of MMSN are able to create a targeted, pH-sensitive template for drug delivery system with application in cancer therapy. [ABSTRACT FROM AUTHOR]

Published
2018
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16. Physiological effects of exogenous nitric oxide on Brassica campestris ssp. Chinensis L. seedlings under salt stress

Author

Luo Man, Zeng Chang-li, and Liu Min-chao

Subjects
biology, fungi, Brassica, food and beverages, biology.organism_classification, APX, chemistry.chemical_compound, chemistry, Seedling, Catalase, Chlorophyll, Botany, biology.protein, Plant hormone, Proline, Peroxidase
Abstract

In the last decade, the role of NO in plants has received much attention. Due to its multifunctional activities in plants, NO is now being considered as a new candidate plant hormone. However, it is not very clear that the physiological mechanism of exogenous NO alleviates salt effects in vegetable plants. Therefore, an experiment was conducted to study the effects of exogenous NO on physiological and biochemical characteristics in Brassica campestris ssp. Chinensis L. seedling leaves under salt stress. In the paper, different concentrations of sodium nitroprussiate (SNP) were served as the NO donor, and first used to irrigate the root of Brassica campestris ssp. Chinensis L. seedlings, then, to pour the seedling leaves. After these inducements of SNP, all treatments were dealt with 150 mM NaCl solution. On the 7th day after salt stress, morphologic characters, physiological and biochemical indexes were mensurated. The results indicated that exogenous NO could significantly improved stem height and diameter, number of leaves, fresh and dry mass and healthy index of seedlings. Moreover, exogenous NO could markedly increase chlorophyll and soluble protein content, free proline content, (SOD), peroxidase (POD), catalase (CAT) and ascorbate peroxidase (APX) activies, while significantly restrain the production of MDA. These results suggested that NO could regulate the antioxidative enzymes activity, mass-eliminate ROS, which improved salt-tolerance ability of Brassica campestris ssp. Chinensis L. seedlings.

Published
2011

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