Search

Your search keyword '"Liu, Rongxian"' showing total 6 results
Start Over Author "Liu, Rongxian"
6 results on '"Liu, Rongxian"'

3. Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine (SAM) binding site in the large polymerase protein

Author

Wang, Yilong, primary, Liu, Rongxian, additional, Lu, Mijia, additional, Yang, Yingzhi, additional, Zhou, Duo, additional, Hao, Xiaoqiang, additional, Zhou, Dongming, additional, Wang, Bin, additional, Li, Jianrong, additional, Huang, Yao-Wei, additional, and Zhao, Zhengyan, additional

Published
2018
Full Text
View/download PDF

4. Taxi vehicle status analysis in China

Author

Liu Xianglong, Liu Rongxian, Wu Zhongyi, Zhang Lihua, and Zhang Haozhi

Subjects
Transport engineering, Engineering, Diesel fuel, business.industry, Emission standard, Compressed natural gas, Energy consumption, Gasoline, business, Green vehicle, Paratransit, Liquefied petroleum gas
Abstract

Taxi is regarded as an important paratransit in China. This paper analyses the current status of China taxi vehicles, including taxi company size, vehicle age, emissions standards and fuel type. The analysis results show that generally the size of taxi companies is small; taxi retirement regulation has not been strictly complied with, currently 1,623 vehicles older than 8 years are still operating; high emission vehicles account for a large proportion of all vehicles (34%), and recent 2 years high-emission vehicles still enter into taxi operating market; moreover, most of the vehicles use gasoline (84.3%) and diesel (6.5%), clean fuel vehicles, such as compressed natural gas (CNG) and liquefied petroleum gas (LPG), are at a very low percentage. Aiming at strengthening taxi vehicle safety, reducing energy consumption and emission, we propose several policy recommendations.

Published
2011

6. Recombinant Chinese Hu191 measles virus exhibits a significant antitumor activity against nephroblastoma mediated by immunogenic form of apoptosis.

Author

Zhu M, Wang Y, Qu C, Liu R, Zhang C, Wang J, Zhou D, Gu W, Chen P, Wu B, and Zhao Z

Abstract

In previous studies oncolytic measles viruses (MVs) have shown significant antitumor activity against various tumors. In our research recombinant MV-Hu191 (rMV-Hu191), established via reverse genetics technology and expressing enhanced green fluorescent protein (EGFP), was evaluated for its therapeutic effects and related mechanisms against nephroblastoma cell lines. We built three different constructs based on rMV-Hu191 to express EGFP effectively. Our experiments showed that rMV-Hu191 expressing EGFP could efficiently infect and replicate in nephroblastoma cell lines. Caspase-induced apoptosis exerted a significant impact on MV-induced cell death, which was accompanied by emission of cellular ATP and high-mobility group protein 1 (HMGB1) and by translocation of calreticulin (CRT). Intratumoral injection of rMV-Hu191-EGFP resulted in significant regression of tumors in a G401 xenograft model. Our results indicate that the MV-Hu191 strain, which is widely used in China, is an appropriate vector for expression of foreign genes and could serve as a potentially good candidate for nephroblastoma therapy mediated by induction of apoptosis-associated immunogenic cell death (ICD)., Competing Interests: None., (AJTR Copyright © 2021.)

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results