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Hyperspectral/multispectral and panchromatic of optical remote sensing images are commonly used for multisensor image fusion, which has been applied in various applications of Earth observation. However, the utilization of optical remote sensing data suffers from the limitation of bad weather and cloud contamination. To address aforementioned issue and enhance spatial details of polarimetric synthetic aperture radar (PolSAR) image, a novel dual-domain super-resolution image fusion method is proposed by combining improved spherically invariant random vector (ISIRV) model with generalized adaptive linear combination approximation (GALCA) technology in this study. The proposed method decomposes the task of image fusion into polarimetric and texture domain fusion by integrating polarimetric components of PolSAR image and texture detail component of panchromatic image, which can significantly improve spatial resolutions of the PolSAR image while preserving polarimetric information. The data fusion experiment is implemented with three data sets including panchromatic images of Gaofen-1 (GF-1) and Gaofen-2 (GF-2) and the quad-pol SAR data of Gaofen-3 (GF-3) and Radarsat-2. Results show that the proposed dual-domain image fusion method provides a better performance compared with state-of-the-art multisensor fusion methods (BT, PCA, GS, indusion, and PRACS) regarding qualitative and quantitative evaluations. In addition, results of image fusion are applied to image classification over agricultural and urban areas of China, which shows that classification accuracy is significantly improved when compared with the result using only the original image. [ABSTRACT FROM AUTHOR]

Although the diagnosis and therapy approach developed, techniques for the early diagnosis of HCC remain insufficient which results in poor prognosis of patients. The traditional biomarker AFP, however, has been proved with low specificity. Circulating exosomal ncRNAs revealed different profiles reflecting the characteristics of tumour. In this study, we mainly focused on circulating exosomal ncRNAs which might be the fingerprint for HCC, especially for the diagnosis or metastasis prediction. A high throughput lncRNA microarray in exosomes extracted from cell‐free plasma was applied. The risk score analysis was employed to screen the potential exosome‐derived lncRNAs in two independent sets based on different clinical parameters in 200 paired HCC patients. After a multi‐stage validation, we finally revealed three lncRNAs, ENSG00000248932.1, ENST00000440688.1 and ENST00000457302.2, increased in HCC comparing with the both chronic hepatitis (CH) patients and cancer‐free controls. ROC curve revealed a higher sensitivity and specificity in predicting the occurrence of HCC from cancer‐free controls and CH patients with the area under curve (AUC) of 0.905 and 0.879 by combining AFP. The three lncRNA panel combined with AFP also indicted a fingerprint function in predicting the metastasis of HCC with the AUC of 0.870. In conclusion, ENSG00000248932.1, ENST00000440688.1 and ENST00000457302.2 might be the potential biomarker for the tumorigenesis prediction from CH patients or healthy controls and may also be applied for dynamic monitoring the metastasis of HCC. [ABSTRACT FROM AUTHOR]

To solve the problems of existing method of change detection using fully polarimetric SAR which not takes full advantage of polarimetric information and the result of false alarm rate of which is high, a method is proposed based on test statistic and Gaussian mixture model in this paper. In the case of the flood disaster in Wuhan city in 2016, difference image is obtained by the likelihoodratio parameter which is built using coherency matrix C3 or covariance matrix T3 of fully polarimetric SAR based on test statistic, and it becomes a reality that the change information is automatic extracted by the parameter of Gaussian mixture model (GMM) of difference image based on the expectation maximization (EM) iterative algorithm. The experimental results show that the overall accuracy of change detection results can be improved and false alarm rate can be reduced using this method by comparison with traditional constant false alarm rate (CFAR) method. Thus the validity and feasibility of the method is demonstrated. [ABSTRACT FROM AUTHOR]