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3,254 results on '"Liu, Yonghong"'

10. Usability Testing for Electronic Remote Control Interaction Interface for Smart Home Products

Author

Li, Fanhao, Liu, Yonghong, Bai, Xiangtian, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Marcus, Aaron, editor, Rosenzweig, Elizabeth, editor, and Soares, Marcelo M., editor

Published
2024
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22. Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population

Author

Pan, Hongxu, Liu, Zhenhua, Ma, Jinghong, Li, Yuanyuan, Zhao, Yuwen, Zhou, Xiaoxia, Xiang, Yaqin, Wang, Yige, Zhou, Xun, He, Runcheng, Xie, Yali, Zhou, Qiao, Yuan, Kai, Xu, Qian, Sun, Qiying, Wang, Junling, Yan, Xinxiang, Zhang, Hainan, Wang, Chunyu, Lei, Lifang, Liu, Weiguo, Wang, Xuejing, Ding, Xuebing, Wang, Tao, Xue, Zheng, Zhang, Zhentao, Chen, Ling, Wang, Qing, Liu, Yonghong, Tang, Jiayu, Zhang, Xuewei, Peng, Shifang, Wang, Chaodong, Ding, Jianqing, Liu, Chunfeng, Wang, Lijuan, Chen, Haibo, Shen, Lu, Jiang, Hong, Wu, Xinyin, Tan, Hongzhuan, Luo, Dan, Xiao, Shuiyuan, Chen, Xiang, Tan, Jieqiong, Hu, Zhengmao, Chen, Chao, Xia, Kun, Zhang, Zhuohua, Foo, Jia Nee, Blauwendraat, Cornelis, Nalls, Mike A., Singleton, Andrew B., Liu, Jun, Chan, Piu, Zheng, Houfeng, Li, Jinchen, Guo, Jifeng, Yang, Jian, and Tang, Beisha

Published
2023
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25. A physical perspective to understand myelin. II. The physical origin of myelin development

Author

Liu, Yonghong, Zhang, Yapeng, Yue, Wenji, Zhu, Ran, Guo, Tianruo, Liu, Fenglin, Huang, Yubin, Wu, Tianzhun, and Wang, Hao

Subjects
Physics - Biological Physics
Abstract

The physical principle of myelin development is obtained from our previous study by explaining Peter's quadrant mystery: an external applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E, to explain more phenomena about myelin development systematically. Specifically, the g-ratio and the fate of the Schwann cell's differentiation are explained in terms of E-field. Moreover, an experiment is proposed to validate this theory.

Published
2021

26. A physical perspective to understand myelin. I. Peters quadrant mystery

Author

Liu, Yonghong, Zhang, Yapeng, Yue, Wenji, Zhu, Ran, Guo, Tianruo, Liu, Fenglin, Huang, Yubin, Wu, Tianzhun, and Wang, Hao

Subjects
Physics - Biological Physics
Abstract

In the development of oligodendrocytes in the central nervous systems, the inner and outer tongue of the myelin sheath tend to be located within the same quadrant, which was named as Peters quadrant mystery. In this study, we conduct in silico investigations to explore the possible mechanisms underlying the Peters quadrant mystery. A biophysically detailed model of oligodendrocytes was used to simulate the effect of the actional potential-induced electric field across the myelin sheath. Our simulation suggests that the paranodal channel connecting the inner and outer tongue forms a low impedance route, inducing two high-current zones at the area around the inner and outer tongue. When the inner tongue and outer tongue are located within the same quadrant, the interaction of these two high-current-zones will induce a maximum amplitude and a polarity reverse of the voltage upon the inner tongue, resulting in the same quadrant phenomenon. This model indicates that the growth of myelin follows a simple principle: an external negative or positive E-field can promote or inhibit the growth of the inner tongue, respectively.

Published
2021

39. Chemotherapy-induced oral mucositis induced by low dose methotrexate: a case report and literature review

Author

WANG Shanshan, MA Xixing, LI Yanling, and LIU Yonghong

Subjects
methotrexate, chemotherapy-induced oral mucositis, psoriasis vulgaris, myelosuppression, chronic periodontitis, granulocyte colony stimulating factor, risk factors, Medicine
Abstract

Objective To investigate the diagnosis and treatment for oral mucositis induced by low-dose methotrexate and to provide a reference for clinicians. Methods A case of severe chemotherapy-induced oral mucositis caused by short-term use of low-dose methotrexate (the maximum cumulative dose within 1 week) was reported and reviewed in combination with the literature. Results The patient was treated with low-dose methotrexate (2.5 mg orally every other day at weeks 1, 2, and 4; the third week, 2.5 mg each time for 3 consecutive days for twice, with a maximum cumulativedose of 15 mg within a week). After irregular medication for approximately three weeks, the patient gradually developed severe erosion of the lips, pain, difficulty eating, and skin erosion on both legs. Methotrexate was stopped after admission, and local symptomatic treatments such as Kangfuxin solution were given. Recombinant human granulocyte colony-stimulating factor was used systemically when combined with neutropenia. After treatment, the chemotherapy-induced oral mucositis and skin lesions were improved. A literature review shows that chemotherapy-induced oral mucositis is a toxic reaction to high-dose methotrexate, while cases of severe chemotherapy-induced oral mucositis caused by low-dose methotrexate are rare. Studies have found that the more risk factors patients have, such as poor local oral conditions and systemic diseases such as liver and kidney dysfunction and diabetes, the higher the risk of chemotherapy-induced oral mucositis. Clinicians should cooperate with dentists to address oral diseases as much as possible before using chemotherapy drugs. In addition, when ordering patients to take methotrexate, we should pay attention to the patient's general condition and susceptibility factors, standardize the frequency and dose of administration, adopt personalized treatment plans, and give patients detailed medication education to prevent the occurrence of adverse consequences caused by medication errors. If methotrexate poisoning occurs, the drug should be stopped in time, detoxification and active symptomatic and supportive treatment should be given. Basic oral care, cryotherapy, laser therapy, nutritional support and analgesic drugs are common treatments for chemotherapy-induced oral mucositis. Systemic administration of granulocyte colony-stimulating factor may be considered when accompanied by neutropenia. Conclusion It is necessary to be alert to the occurrence of severe chemotherapy-induced oral mucositis caused by low-dose methotrexate in clinical practice.

Published
2023
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