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18 results on '"Liu, Zhangyuanzhu"'

10. Development and Validation of a Collagen Nomogram for Pretreatment Prediction of Pathological Complete Response in Rectal Cancer Patients

Author

Jiang, Wei, primary, Wang, Shijie, additional, Liu, Zhangyuanzhu, additional, Zheng, Jixiang, additional, Li, Min, additional, Dong, Xiaoyu, additional, Yan, Botao, additional, Cheng, Jiaxin, additional, Wang, Guangxing, additional, Xu, Shuoyu, additional, Xiao, Weiwei, additional, Gao, Yuanhong, additional, Zhuo, Shuangmu, additional, and Yan, Jun, additional

Published
2021
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11. Association of the Collagen Signature in the Tumor Microenvironment With Lymph Node Metastasis in Early Gastric Cancer

Author

Chen, Dexin, primary, Chen, Gang, additional, Jiang, Wei, additional, Fu, Meiting, additional, Liu, Wenju, additional, Sui, Jian, additional, Xu, Shuoyu, additional, Liu, Zhangyuanzhu, additional, Zheng, Xiaoling, additional, Chi, Liangjie, additional, Lin, Dajia, additional, Li, Kai, additional, Chen, Weisheng, additional, Zuo, Ning, additional, Lu, Jianping, additional, Chen, Jianxin, additional, Li, Guoxin, additional, Zhuo, Shuangmu, additional, and Yan, Jun, additional

Published
2019
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12. Real-time in vivo optical biopsy using confocal laser endomicroscopy to evaluate distal margin in situ and determine surgical procedure in low rectal cancer

Author

Liu, Zhangyuanzhu, primary, Luo, Xiaobei, additional, Jiang, Wei, additional, Chen, Dexin, additional, Chen, Weisheng, additional, Li, Kai, additional, Liu, Xiumin, additional, Cui, Ziming, additional, Li, Zhiming, additional, Han, Zelong, additional, Liu, Side, additional, Li, Guoxin, additional, Xu, Chris, additional, and Yan, Jun, additional

Published
2018
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14. Multiphoton imaging provides a superior optical biopsy to that of confocal laser endomicroscopy imaging for colorectal lesions

Author

Yan, Jun, additional, Zheng, Xiaoling, additional, Liu, Zhangyuanzhu, additional, Liu, Wenju, additional, Lin, Dajia, additional, Chen, Dexin, additional, Li, Kai, additional, Jiang, Wei, additional, Li, Zhiming, additional, Zuo, Ning, additional, Chen, Gang, additional, Lu, Jianping, additional, Chen, Jianxin, additional, Li, Guoxin, additional, Xu, Chris, additional, and Zhuo, Shuangmu, additional

Published
2018
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15. Multiphoton imaging provides a superior optical biopsy to that of confocal laser endomicroscopy imaging for colorectal lesions.

Author

Jun Yan, Xiaoling Zheng, Zhangyuanzhu Liu, Wenju Liu, Dajia Lin, Dexin Chen, Kai Li, Wei Jiang, Zhiming Li, Ning Zuo, Gang Chen, Jianping Lu, Jianxin Chen, Guoxin Li, Chris Xu, Shuangmu Zhuo, Yan, Jun, Zheng, Xiaoling, Liu, Zhangyuanzhu, and Liu, Wenju

Subjects
COLON cancer, FLUORESCENCE, DIAGNOSTIC imaging
Abstract

Background: Confocal laser endomicroscopy (CLE) requires fluorescence agents, the use of which leads to blurred images and low diagnostic accuracy owing to fluorescein leakage. We aimed to explore whether multiphoton imaging (MPI) could serve as a better method of optical biopsy.Methods: First, a pilot study was performed to set up the optical diagnostic criteria of MPI for benign or malignant colorectal lesions in 30 patients. Then, a blinded study was conducted to compare the sensitivity, specificity, and accuracy of MPI versus CLE imaging in 79 patients. RESULTS : In the pilot study, MPI revealed regular tissue architecture and cell morphology in the normal tissue, and irregular tubular structures, and cellular and nuclear pleomorphism in the abnormal tissue. In the blinded study, compared with CLE imaging, MPI significantly improved the diagnostic sensitivity, specificity, and accuracy of the optical biopsy (89.74 % vs. 61.54 %, P = 0.008; 92.5 % vs. 67.5 %, P = 0.009; and 91.14 % vs. 64.56 %, P = 0.001, respectively). CONCLUSIONS : MPI can provide a superior optical biopsy to that of CLE imaging for colorectal lesions. [ABSTRACT FROM AUTHOR]

Published
2019
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16. Real-time optical diagnosis of gastric cancer with serosal invasion using multiphoton imaging

Author

Yan, Jun, primary, Zheng, Yu, additional, Zheng, Xiaoling, additional, Liu, Zhangyuanzhu, additional, Liu, Wenju, additional, Chen, Dexin, additional, Dong, Xiaoyu, additional, Li, Kai, additional, Liu, Xiumin, additional, Chen, Gang, additional, Lu, Jianping, additional, Chen, Jianxin, additional, Zhuo, Shuangmu, additional, and Li, Guoxin, additional

Published
2016
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17. A multicenter study of using carbon nanoparticles to show sentinel lymph nodes in early gastric cancer

Author

Yan, Jun, primary, Zheng, Xiaoling, additional, Liu, Zhangyuanzhu, additional, Yu, Jiang, additional, Deng, Zhenwei, additional, Xue, Fangqing, additional, Zheng, Yu, additional, Chen, Feng, additional, Shi, Hong, additional, Chen, Gang, additional, Lu, Jianping, additional, Cai, Lisheng, additional, Cai, Mingzhi, additional, Xiang, Gao, additional, Hong, Yunfeng, additional, Chen, Wenbo, additional, and Li, Guoxin, additional

Published
2015
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18. Multiphoton imaging provides a superior optical biopsy to that of confocal laser endomicroscopy imaging for colorectal lesions.

Author

Yan J, Zheng X, Liu Z, Liu W, Lin D, Chen D, Li K, Jiang W, Li Z, Zuo N, Chen G, Lu J, Chen J, Li G, Xu C, and Zhuo S

Subjects
Adult, Aged, Female, Humans, Male, Middle Aged, Pilot Projects, Sensitivity and Specificity, Colorectal Neoplasms pathology, Image-Guided Biopsy, Microscopy, Confocal, Optical Imaging methods
Abstract

Background: Confocal laser endomicroscopy (CLE) requires fluorescence agents, the use of which leads to blurred images and low diagnostic accuracy owing to fluorescein leakage. We aimed to explore whether multiphoton imaging (MPI) could serve as a better method of optical biopsy., Methods: First, a pilot study was performed to set up the optical diagnostic criteria of MPI for benign or malignant colorectal lesions in 30 patients. Then, a blinded study was conducted to compare the sensitivity, specificity, and accuracy of MPI versus CLE imaging in 79 patients. RESULTS : In the pilot study, MPI revealed regular tissue architecture and cell morphology in the normal tissue, and irregular tubular structures, and cellular and nuclear pleomorphism in the abnormal tissue. In the blinded study, compared with CLE imaging, MPI significantly improved the diagnostic sensitivity, specificity, and accuracy of the optical biopsy (89.74 % vs. 61.54 %, P  = 0.008; 92.5 % vs. 67.5 %, P  = 0.009; and 91.14 % vs. 64.56 %, P  = 0.001, respectively). CONCLUSIONS : MPI can provide a superior optical biopsy to that of CLE imaging for colorectal lesions., Competing Interests: None, (© Georg Thieme Verlag KG Stuttgart · New York.)

Published
2019
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