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669 results on '"Lockey, R."'

3. Optoelectronic time-division multiplexing for multicomponent laser Doppler anemometry

Author

Lockey, R. A. and Tatum, R. P.

Subjects
535, Optical fibres
Abstract

This thesis describes the investigation of time-division multiplexing for use in mUlticomponent laser Doppler anemometry (LDA). To make two- or three- dimensional velocity measurements of a flow, two or three separate velocity measurements in different, non-collinear or non-coplanar directions respectively must be taken from which the flow vector can be calculated. It is necessary to separate each velocity channel. Conventionally, the separation is carried out by optical techniques, such as separating the signal from each channel by wavelength or polarisation, with one detector per channel. In time division multiplexing, each channel is switched On and off in turn. A single detector records a stream of interleaved pulses, and each channel is extracted by taking every other or every third pulse. The envelope of the amplitudes of the pulses varies at the Doppler frequency. A novel system has been demonstrated which uses a single laser diode source and a single detector. The distribution of the pulses to each channel and the delay between each channel is carried out using a optical fibre network with fibre delay lines, with a consequent reduction in 'electronic complexity. The characteristics of the optoelectronic components used in the system are tested, and two signal processing schemes are investigated. A two-dimensional Doppler difference fibre-linked probe was constructed to demonstrate the technique. Hybrid instruments using two Doppler difference channels and a reference beam channel to measure orthogonal velocity components offer the possibility of avoiding the errors introduced by non-orthogonal systems. A pulsed-diode reference beam anemometer based on optical fibres and suitable for inclusion in a time-division multiplexed hybrid instrument was tested.

Published
1996

8. WAO/EAACI.

Author

Maurer, M., Magerl, M., Ansotegui, I., Aygören-Pürsün, E., Betschel, S., Bork, K., Bowen, T., Balle Boysen, H., Farkas, H., Grumach, A. S., Hide, M., Katelaris, C., Lockey, R., Longhurst, H., Lumry, W. R., Martinez-Saguer, I., Moldovan, D., Nast, A., Pawankar, R., and Potter, P.

Published
2023

10. Transmission and characterisation of atypical scrapie cases from Great Britain in transgenic and wild-type mice

Author

Griffiths, PC, Spiropoulos, J, Lockey, R, Tout, AC, Jayasena, D, Plater, JM, Chave, A, Simonini, S, Dexter, I, Buschmann, A, Groschup, MH, Beringue, Vincent, Le Dur, Annick, Laude, Hubert, Simmons, MM, Hope, Jane, Inconnu, Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), and Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

11. Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

Author

Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., van Wijk, Gerth R., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P., Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R., OʼHehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pawankar, R., Price, D., Ryan, D., Simons, F. E.R., Togias, A., Williams, D., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I., Aït-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghé, B., Beji, M., Bel, E. H., Ben Kheder, A., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Bieber, T., Bindslev Jensen, C., Blaiss, M. S., Boner, A. L., Bouchard, J., Braido, F., Brightling, C. E., Bush, A., Caballero, F., Calderon, M. A., Calvo, M. A., Camargos, P. A.M., Caraballo, L. R., Carlsen, K. H., Carr, W., Cepeda, A. M., Cesario, A., Chavannes, N. H., Chen, Y. Z., Chiriac, A. M., Chivato Pérez, T., Chkhartishvili, E., Ciprandi, G., Costa, D. J., Cox, L., Custovic, A., Dahl, R., Darsow, U., De Blay, F., Deleanu, D., Denburg, J. A., Devillier, P., Didi, T., Dokic, D., Dolen, W. K., Douagui, H., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., El-Meziane, A., Emuzyte, R., Fiocchi, A., Fletcher, M., Fukuda, T., Gamkrelidze, A., Gereda, J. E., González Diaz, S., Gotua, M., Guzmán, M. A., Hellings, P. W., Hellquist-Dahl, B., Horak, F., Hourihane, Oʼ B.J., Howarth, P., Humbert, M., Ivancevich, J. C., Jackson, C., Just, J., Kalayci, O., Kaliner, M. A., Kalyoncu, A. F., Keil, T., Keith, P. K., Khayat, G., Kim, Y. Y., Koffi NʼGoran, B., Koppelman, G. H., Kowalski, M. L., Kull, I., Kvedariene, V., Larenas-Linnemann, D., Le, L. T., Lemière, C., Li, J., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, M. R., Maurer, M., Mavale-Manuel, S., Mazon, A., Melen, E., Meltzer, E. O., Mendez, N. H., Merk, H., Mihaltan, F., Mohammad, Y., Morais-Almeida, M., Muraro, A., Nafti, S., Namazova-Baranova, L., Nekam, K., Neou, A., Niggemann, B., Nizankowska-Mogilnicka, E., Nyembue, T. D., Okamoto, Y., Okubo, K., Orru, M. P., Ouedraogo, S., Ozdemir, C., Panzner, P., Pali-Schöll, I., Park, H. S., Pigearias, B., Pohl, W., Popov, T. A., Postma, D. S., Potter, P., Rabe, K. F., Ratomaharo, J., Reitamo, S., Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado-Pinto, J., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Scadding, G. K., Schmid-Grendelmeier, P., Sheikh, A., Sisul, J. C., Solé, D., Sooronbaev, T., Spicak, V., Spranger, O., Stein, R. T., Stoloff, S. W., Sunyer, J., Szczeklik, A., Todo-Bom, A., Toskala, E., Tremblay, Y., Valenta, R., Valero, A. L., Valeyre, D., Valiulis, A., Valovirta, E., Van Cauwenberge, P., Vandenplas, O., van Weel, C., Vichyanond, P., Viegi, G., Wang, D. Y., Wickman, M., Wöhrl, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Zar, H. J., Zernotti, M. E., Zhong, N., Zidarn, M., and Zuberbier, T.

Published
2012
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13. International consensus on (ICON) pediatric asthma

Author

Papadopoulos, N. G., Arakawa, H., Carlsen, K.-H., Custovic, A., Gern, J., Lemanske, R., Le Souef, P., Mäkelä, M., Roberts, G., Wong, G., Zar, H., Akdis, C. A., Bacharier, L. B., Baraldi, E., van Bever, H. P., de Blic, J., Boner, A., Burks, W., Casale, T. B., Castro-Rodriguez, J. A., Chen, Y. Z., El-Gamal, Y. M., Everard, M. L., Frischer, T., Geller, M., Gereda, J., Goh, D. Y., Guilbert, T. W., Hedlin, G., Heymann, P. W., Hong, S. J., Hossny, E. M., Huang, J. L., Jackson, D. J., de Jongste, J. C., Kalayci, O., Aït-Khaled, N., Kling, S., Kuna, P., Lau, S., Ledford, D. K., Lee, S. I., Liu, A. H., Lockey, R. F., Ldrup-Carlsen, K., Lötvall, J., Morikawa, A., Nieto, A., Paramesh, H., Pawankar, R., Pohunek, P., Pongracic, J., Price, D., Robertson, C., Rosario, N., Rossenwasser, L. J., Sly, P. D., Stein, R., Stick, S., Szefler, S., Taussig, L. M., Valovirta, E., Vichyanond, P., Wallace, D., Weinberg, E., Wennergren, G., Wildhaber, J., and Zeiger, R. S.

Published
2012
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20. Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

Author

Bousquet, J., Schünemann, H. J., Zuberbier, T., Bachert, C., Baena-Cagnani, C. E., Bousquet, P. J., Brozek, J., Canonica, G. W., Casale, T. B., Demoly, P., Gerth van Wijk, R., Ohta, K., Bateman, E. D., Calderon, M., Cruz, A. A., Dolen, W. K., Haughney, J., Lockey, R. F., Lötvall, J., OʼByrne, P., Spranger, O., Togias, A., Bonini, S., Boulet, L. P., Camargos, P., Carlsen, K. H., Chavannes, N. H., Delgado, L., Durham, S. R., Fokkens, W. J., Fonseca, J., Haahtela, T., Kalayci, O., Kowalski, M. L., Larenas-Linnemann, D., Li, J., Mohammad, Y., Mullol, J., Naclerio, R., OʼHehir, R. E., Papadopoulos, N., Passalacqua, G., Rabe, K. F., Pawankar, R., Ryan, D., Samolinski, B., Simons, F. E. R., Valovirta, E., Yorgancioglu, A., Yusuf, O. M., Agache, I., Aït-Khaled, N., Annesi-Maesano, I., Beghe, B., Ben Kheder, A., Blaiss, M. S., Boakye, D. A., Bouchard, J., Burney, P. G., Busse, W. W., Chan-Yeung, M., Chen, Y., Chuchalin, A. G., Costa, D. J., Custovic, A., Dahl, R., Denburg, J., Douagui, H., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S. L., Kaliner, M. A., Keith, P. K., Kim, Y. Y., Klossek, J. M., Kuna, P., Le, L. T., Lemiere, C., Lipworth, B., Mahboub, B., Malo, J. L., Marshall, G. D., Mavale-Manuel, S., Meltzer, E. O., Morais-Almeida, M., Motala, C., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M. P., Ouedraogo, S., Palkonen, S., Popov, T. A., Price, D., Rosado-Pinto, J., Scadding, G. K., Sooronbaev, T. M., Stoloff, S. W., Toskala, E., van Cauwenberge, P., Vandenplas, O., van Weel, C., Viegi, G., Virchow, J. C., Wang, D. Y., Wickman, M., Williams, D., Yawn, B. P., Zar, H. J., Zernotti, M., and Zhong, N.

Published
2010
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25. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 Update (in collaboration with the World Health Organization, GA2LEN and AllerGen)

Author

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W. J., Togias, A., Zuberbier, T., Baena-Cagnani, C. E., Canonica, G. W., van Weel, C., Agache, I., Aït-Khaled, N., Bachert, C., Blaiss, M. S., Bonini, S., Boulet, L.-P., Bousquet, P.-J., Camargos, P., Carlsen, K.-H., Chen, Y., Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S. R., van Wijk, R. Gerth, Kalayci, O., Kaliner, M. A., Kim, Y.-Y., Kowalski, M. L., Kuna, P., Le, L. T. T., Lemiere, C., Li, J., Lockey, R. F., Mavale-Manuel, S., Meltzer, E. O., Mohammad, Y., Mullol, J., Naclerio, R., OʼHehir, R. E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T. A., Rabe, K. F., Rosado-Pinto, J., Scadding, G. K., Simons, F. E. R., Toskala, E., Valovirta, E., van Cauwenberge, P., Wang, D.-Y., Wickman, M., Yawn, B. P., Yorgancioglu, A., Yusuf, O. M., Zar, H., Annesi-Maesano, I., Bateman, E. D., Kheder, A. Ben, Boakye, D. A., Bouchard, J., Burney, P., Busse, W. W., Chan-Yeung, M., Chavannes, N. H., Chuchalin, A., Dolen, W. K., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S. L., Keith, P. K., Kemp, J. P., Klossek, J.-M., Larenas-Linnemann, D., Lipworth, B., Malo, J.-L., Marshall, G. D., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M. P., Potter, P., Price, D., Stoloff, S. W., Vandenplas, O., Viegi, G., and Williams, D.

Published
2008

27. Pharmacologic and anti-IgE treatment of allergic rhinitis ARIA update (in collaboration with GA2LEN)

Author

Bousquet, J., van Cauwenberge, P., Aït Khaled, N., Bachert, C., Baena-Cagnani, C. E., Bouchard, J., Bunnag, C., Canonica, G. W., Carlsen, K.-H., Chen, Y.-Z., Cruz, A. A., Custovic, A., Demoly, P., Dubakiene, R., Durham, S., Fokkens, W., Howarth, P., Kemp, J., Kowalski, M. L., Kvedariene, V., Lipworth, B., Lockey, R., Lund, V., Mavale-Manuel, S., Meltzer, E. O., Mullol, J., Naclerio, R., Nekam, K., Ohta, K., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T., Potter, P., Price, D., Scadding, G., Simons, F. E. R., Spicak, V., Valovirta, E., Wang, D.-Y., Yawn, B., and Yusuf, O.

Published
2006

42. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2017 revision and update

Author

Maurer, M., primary, Magerl, M., additional, Ansotegui, I., additional, Aygören-Pürsün, E., additional, Betschel, S., additional, Bork, K., additional, Bowen, T., additional, Balle Boysen, H., additional, Farkas, H., additional, Grumach, A. S., additional, Hide, M., additional, Katelaris, C., additional, Lockey, R., additional, Longhurst, H., additional, Lumry, W. R., additional, Martinez-Saguer, I., additional, Moldovan, D., additional, Nast, A., additional, Pawankar, R., additional, Potter, P., additional, Riedl, M., additional, Ritchie, B., additional, Rosenwasser, L., additional, Sánchez-Borges, M., additional, Zhi, Y., additional, Zuraw, B., additional, and Craig, T., additional

Published
2018
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43. ELECTRON BEAM ION SOURCE PREINJECTOR PROJECT (EBIS) CONCEPTUAL DESIGN REPORT.

Author

ALESSI, J., primary, BARTON, D., additional, BEEBE, E., additional, GASSNER, D., additional, GRANDINETTI, R., additional, HSEUH, H., additional, JAVIDFAR, A., additional, KPONOU, A., additional, LAMBIASE, R., additional, LESSARD, E., additional, LOCKEY, R., additional, LODESTRO, V., additional, MAPES, M., additional, MIRABELLA, D., additional, NEHRING, T., additional, OERTER, B., additional, PENDZICK, A., additional, PIKIN, A., additional, RAPARIA, D., additional, RITTER, J., additional, ROSER, T., additional, RUSSO, T., additional, SNYDSTRUP, L., additional, WILINSKI, M., additional, ZALTSMAN, A., additional, and ZHANG, S., additional

Published
2005
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44. Induction of IgE Synthesis: Cellular Interactions and Molecular Events

Author

Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), van de Veen, W, Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), and van de Veen, W

Published
2014

45. Specific IgE

Author

Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), van de Veen, W, Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), and van de Veen, W

Published
2014

46. IgE Isotype Switching

Author

Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), van de Veen, W, Mackay, I R, Rose, N R, Ledford, D K, Lockey, R F, Mackay, I R ( I R ), Rose, N R ( N R ), Ledford, D K ( D K ), Lockey, R F ( R F ), and van de Veen, W

Published
2014

50. Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?

Author

Simmons, M. M., Chaplin, M. J., Vickery, C. M., Simon, S., Davis, L., Denyer, M., Lockey, R., Stack, M. J., O'Connor, M. J., Thorne, L., Spiropoulos, J., Bishop, K., Gough, K. C., Maddison, B. C., and Fenwick, B. W.

Subjects
animal diseases, mental disorders, food and beverages, nervous system diseases
Abstract

Current European Commission (EC) surveillance regulations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive small ruminant (SR) samples in order to classify them as bovine spongiform encephalopathy (BSE) or non-BSE. This requires a range of tests, including characterization by bioassay in mouse models. Since 2005, naturally occurring BSE has been identified in two goats. It has also been demonstrated that more than one distinct TSE strain can coinfect a single animal in natural field situations. This study assesses the ability of the statutory methods as listed in the regulation to identify BSE in a blinded series of brain samples, in which ovine BSE and distinct isolates of scrapie are mixed at various ratios ranging from 99% to 1%. Additionally, these current statutory tests were compared with a new in vitro discriminatory method, which uses serial protein misfolding cyclic amplification (sPMCA). Western blotting consistently detected 50% BSE within a mixture, but at higher dilutions it had variable success. The enzyme-linked immunosorbent assay (ELISA) method consistently detected BSE only when it was present as 99% of the mixture, with variable success at higher dilutions. Bioassay and sPMCA reported BSE in all samples where it was present, down to 1%. sPMCA also consistently detected the presence of BSE in mixtures at 0.1%. While bioassay is the only validated method that allows comprehensive phenotypic characterization of an unknown TSE isolate, the sPMCA assay appears to offer a fast and cost-effective alternative for the screening of unknown isolates when the purpose of the investigation was solely to determine the presence or absence of BSE.

Published
2015

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