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28 results on '"Loesch, Andreas"'

1. Overcoming Observation Bias for Cancer Progression Modeling

Author

Schill, Rudolf, Klever, Maren, Lösch, Andreas, Hu, Y. Linda, Vocht, Stefan, Rupp, Kevin, Grasedyck, Lars, Spang, Rainer, Beerenwinkel, Niko, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, and Ma, Jian, editor

Published
2024
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2. Differentiated uniformization: A new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models

Author

Rupp, Kevin, Schill, Rudolf, Süskind, Jonas, Georg, Peter, Klever, Maren, Lösch, Andreas, Grasedyck, Lars, Wettig, Tilo, and Spang, Rainer

Subjects
Statistics - Machine Learning, Computer Science - Machine Learning, Quantitative Biology - Populations and Evolution
Abstract

Motivation: We consider continuous-time Markov chains that describe the stochastic evolution of a dynamical system by a transition-rate matrix $Q$ which depends on a parameter $\theta$. Computing the probability distribution over states at time $t$ requires the matrix exponential $\exp(tQ)$, and inferring $\theta$ from data requires its derivative $\partial\exp\!(tQ)/\partial\theta$. Both are challenging to compute when the state space and hence the size of $Q$ is huge. This can happen when the state space consists of all combinations of the values of several interacting discrete variables. Often it is even impossible to store $Q$. However, when $Q$ can be written as a sum of tensor products, computing $\exp(tQ)$ becomes feasible by the uniformization method, which does not require explicit storage of $Q$. Results: Here we provide an analogous algorithm for computing $\partial\exp\!(tQ)/\partial\theta$, the differentiated uniformization method. We demonstrate our algorithm for the stochastic SIR model of epidemic spread, for which we show that $Q$ can be written as a sum of tensor products. We estimate monthly infection and recovery rates during the first wave of the COVID-19 pandemic in Austria and quantify their uncertainty in a full Bayesian analysis. Availability: Implementation and data are available at https://github.com/spang-lab/TenSIR.

Published
2021

3. Technology Assessment of Socio-Technical Futures—A Discussion Paper

Author

Lösch, Andreas, Böhle, Knud, Coenen, Christopher, Dobroc, Paulina, Heil, Reinhard, Grunwald, Armin, Scheer, Dirk, Schneider, Christoph, Ferrari, Arianna, Hommrich, Dirk, Sand, Martin, Aykut, Stefan C., Dickel, Sascha, Fuchs, Daniela, Kastenhofer, Karen, Torgersen, Helge, Gransche, Bruno, Hausstein, Alexandra, Konrad, Kornelia, Nordmann, Alfred, Schaper-Rinkel, Petra, Schulz-Schaeffer, Ingo, Wentland, Alexander, Grunwald, Armin, Series Editor, Heil, Reinhard, Series Editor, Coenen, Christopher, Series Editor, Lösch, Andreas, editor, Meister, Martin, editor, and Schulz-Schaeffer, Ingo, editor

Published
2019
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4. Visionary Practices Shaping Power Constellations

Author

Lösch, Andreas, Heil, Reinhard, Schneider, Christoph, Grunwald, Armin, Series Editor, Heil, Reinhard, Series Editor, Coenen, Christopher, Series Editor, Lösch, Andreas, editor, Meister, Martin, editor, and Schulz-Schaeffer, Ingo, editor

Published
2019
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7. Techniksoziologie

Author

Lösch, Andreas, Maasen, Sabine, editor, Kaiser, Mario, editor, Reinhart, Martin, editor, and Sutter, Barbara, editor

Published
2012
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14. Technology Assessment of Socio-Technical Futures: A Discussion Paper

Author

Loesch, Andreas, Boehle, Knud, Coenen, Christopher, Dobroc, Paulina, Heil, Reinhard, Grunwald, Armin, Scheer, Dirk, Schneider, Christoph, Ferrari, Ariana, Hommrich, Dirk, Sand, Martin, Aykut, Stefan, Dickel, Sascha, Fuchs, Daniela, Kastenhofer, Karen, Torgersen, Helge, Gransche, Bruno, Hausstein, Alexandra, Konrad, Kornelia, Nordmann, Alfred, Schaper-Rinkel, Petra, Schulz-Schaeffer, Ingo, Wentland, Alexander, Meister, Martin, and Science, Technology & Policy Studies

Subjects
Functional role, Technological research, Vision, Civil society, Politics, Sociotechnical system, business.industry, Political science, Technology assessment, Public relations, business, Futures contract, ddc
Abstract

Problem: Visions of technology, future scenarios, guiding visions (Leitbilder) represent imaginations of future states of affairs that play a functional role in processes of technological research, development and innovation—e.g. as a means to create attention, communication, coordination, or for the strategic exertion of influence. Since a couple of years there is a growing attention for such imaginations of futures in politics, the economy, research and the civil society. This trend concerns technology assessment (TA) as an observer of these processes and a consultant on the implications of technology and innovation. TA faces increasing demands to assess imaginations of futures that circulate in the present and to participate in shaping these through scenarios or foresights. More than ever, this raises the question, which propositions can be made based on these imaginations by TA and how this can be used in advisory practices. Imaginations of futures are relevant for TA not as predictions but in their significance and effectiveness in the present, which need to be understood and assessed.

Published
2019

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