10 results on '"Logani SC"'
Search Results
2. Lithium aluminium hydride-aluminium chloride reduction of steroidal cyclic acetals.
- Author
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Ahmad, MS and Logani, SC
- Abstract
Lithium aluminium hydride-aluminium chloride (1 : 1, AlH2Cl) reduction of 3,3-ethylenedioxycholest-5-ene (5), 3,3-ethylenedioxy-5α-oholestane (7), 6,6-ethyl-enedioxy-5α-cholestane (7), and 3,3-(1?- methylethylenedioxy)cholest-5-en (8a), gave the glycol ethers (9), (17), (21a), and (24), respectively. The structures of the ethers (9), (17), (21a), and (24) have been established by their spectral properties and chemical transformations. A mechanism of the hydrogenolysis is presented.
- Published
- 1971
- Full Text
- View/download PDF
3. 6b-(2'-Hydroxyethoxy)-5a-cholestan-3b-ol 2',3'-diacetate.
- Author
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Ahmad, MS, Shafiullah, ., and Logani, SC
- Abstract
No abstract available.
- Published
- 1968
- Full Text
- View/download PDF
4. Correlation of preoperative computed tomography and postoperative ocular motility in orbital blowout fractures.
- Author
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Harris GJ, Garcia GH, Logani SC, and Murphy ML
- Subjects
- Cohort Studies, Diplopia physiopathology, Humans, Orbit diagnostic imaging, Orbit physiopathology, Orbital Fractures surgery, Postoperative Care, Preoperative Care, Retrospective Studies, Vision, Binocular physiology, Visual Fields physiology, Eye Movements, Orbit injuries, Orbital Fractures diagnostic imaging, Orbital Fractures physiopathology, Tomography, X-Ray Computed
- Abstract
Purpose: To determine a relationship between preoperative soft tissue disruption and postoperative ocular motility in orbital blowout fractures., Methods: This retrospective cohort study reviewed 30 patients who met all criteria: retrievable coronal computed tomography (CT) scans; internal fractures of the orbital floor, with or without medial wall extension; preoperative diplopia; repair by a single surgeon; complete release of entrapped tissues; and postoperative binocular visual fields (BVFs). Motility outcomes were quantified by one group of the authors, who measured the vertical fusion within BVFs. Other authors analyzed CT scans, designating each fracture as either A or B, based on lesser or greater soft tissue distortion relative to the configuration of bone fragments. The interval between trauma and surgery was also determined., Results: Among the 15 patients with a postoperative motility outcome poorer than the median (86 degrees or less), four (27%) had A fractures; 11 (73%) had B fractures. Among the 15 patients with an outcome better than the median (88 degrees or more), 10 (67%) had A fractures; five (33%) had B fractures. Differences were more defined away from the median. Among five patients with B fractures and better than the median result, three (60%) had surgical repair during the first week after injury. Among the 11 patients with B fractures and less than the median result, one (9%) had repair during the first week., Conclusions: Postoperative motility is influenced by soft tissue-bone fragment relationships. Whether the outcome can be altered by earlier surgery in selected cases will be determined by prospective studies.
- Published
- 2000
- Full Text
- View/download PDF
5. Eyelid crease incision for lateral orbitotomy.
- Author
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Harris GJ and Logani SC
- Subjects
- Aged, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Orbit pathology, Orbital Diseases diagnosis, Retrospective Studies, Surgical Flaps, Tomography, X-Ray Computed, Eyelids surgery, Ophthalmologic Surgical Procedures methods, Orbit surgery, Orbital Diseases surgery
- Abstract
Purpose: The authors describe a surgical incision and technique for lateral orbitotomy that is intended to minimize visible scarring and deformity., Methods: This is a noncomparative, interventional, retrospective case series. Other surgical approaches for lateral orbitotomy are briefly reviewed. The authors' technique includes incision placement within the natural upper eyelid crease, with minimal extension in a relaxed skin tension line; dissection to the superior and lateral orbital rims in the submuscular plane; and wide dissection within the subperiosteal space. Criteria are described for inclusion of a bone flap in the technique., Results: The eyelid crease incision has been used for exposure of the superolateral diagonal half of the orbit in approximately 600 cases. A variety of pathologic conditions affecting the orbital bones or the subperiosteal, extraconal, or intraconal spaces have been treated. Surgical exposure has been adequate to achieve the goals of surgery in individual cases, and the cosmetic results have been preferable to those the authors achieved using other surgical incisions., Conclusions: The eyelid crease incision for lateral orbitotomy allows dissection in relatively avascular planes, involves minimal transection of orbicularis muscle and lymphatic channels, and results in negligible postoperative scarring. Depending on the size and location of the lesion and the goal of surgery, the eyelid crease incision may be used without a bone flap. However, when a bone flap is needed, the incision does not restrict its size.
- Published
- 1999
- Full Text
- View/download PDF
6. Multiple aesthetic unit flaps for medial canthal reconstruction.
- Author
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Harris GJ and Logani SC
- Subjects
- Humans, Blepharoplasty methods, Carcinoma, Basal Cell surgery, Eyelid Neoplasms surgery, Surgical Flaps
- Abstract
The medial canthal region includes several individual aesthetic units that differ in skin quality and thickness, contour, and associated landmarks. Basal cell carcinomas commonly involve the medial canthal region and extend without respecting the boundaries between units. Reconstruction of tumor-free defects is often complicated by web formation across the medial canthal concavity. To avoid this complication, we evaluate each defect according to the anatomic units involved and develop individual flaps from each component area, anchoring each flap to the medial canthal tendon or associated deep fibrous tissue. This system has been used in 58 cases with excellent results. It allows flexibility for reconstructing the many diverse defects that oculoplastic surgeons encounter and helps to minimize postoperative deformity.
- Published
- 1998
- Full Text
- View/download PDF
7. Near-resonance saturation pulse imaging of the extraocular muscles in thyroid-related ophthalmopathy.
- Author
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Ulmer JL, Logani SC, Mark LP, Hamilton CA, Prost RW, and Garman JN
- Subjects
- Adult, Computer Simulation, Female, Humans, Male, Middle Aged, Reference Values, Graves Disease diagnosis, Magnetic Resonance Imaging methods, Oculomotor Muscles pathology
- Abstract
Purpose: We examined the utility of near-resonance saturation pulse imaging (magnetization transfer [MT] and spin lock) in characterizing microstructural changes occurring in the extraocular muscles of patients with thyroid-related ophthalmopathy (TRO)., Methods: Eight healthy volunteers and 10 patients with TRO were imaged using an off-resonance saturation pulse in conjunction with conventional spin-echo T1-weighted imaging at frequency offsets of 500, 1000, 1500, and 2000 Hz from water resonance. The relative contributions of MT and spin-lock excitation to image contrast at each frequency offset were estimated using a computer simulation model. Suppression ratios were calculated for the control and TRO groups from measurements obtained on two successive coronal sections in the widest portion of the inferior and medial rectus muscles bilaterally. A repeated measures analysis of variance and a parametric correlation analysis were performed to evaluate maximum cross-sectional area, MR-generated signal, and suppression ratios for the extraocular muscles examined., Results: Our computer model suggested that saturation of extraocular muscles was due to pure MT effects with our off-resonance pulse at 2000 and 1500 Hz, to a combination of MT and spin lock at 1000 Hz frequency offset, and, primarily, to spin-lock excitation at 500 Hz frequency offset. Suppression ratios for the extraocular muscles of the TRO patients were significantly lower than that observed for the control subjects at 1500, 1000, and 500 Hz frequency offset. This differential saturation effect was maximal at 500 Hz frequency offset, with mean suppression ratios for the inferior and medial rectus muscles of 27% for the healthy subjects and 20% for the TRO group., Conclusion: Both MT and spin-lock contrast of the extraocular muscles in patients with TRO differ significantly from that observed in control subjects. Near-resonance saturation pulse imaging may enhance our understanding of the microstructural changes occurring in the extraocular muscles of these patients.
- Published
- 1998
8. Paralytic ectropion: a complication of malar implant surgery.
- Author
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Logani SC, Conn H, Logani S, and Terino EO
- Subjects
- Aged, Ectropion pathology, Ectropion therapy, Facial Paralysis pathology, Facial Paralysis therapy, Female, Humans, Male, Prosthesis Implantation, Surgery, Plastic, Zygoma surgery, Ectropion etiology, Facial Paralysis etiology, Prostheses and Implants adverse effects
- Abstract
The use of the malar implant to augment the malar-zygomatic eminence is rapidly becoming a popular aesthetic procedure; however, this surgery can lead to paralysis or paresis of the facial nerve. Paralytic ectropion may result from orbicularis oculi dysfunction. We report two cases of paralytic ectropion as a result of malar implant placement. Conservative management for mild orbicularis oculi dysfunction consisted of topical lubricants and observation, whereas persistent ectropion required surgical repair. Paralytic ectropion and secondary exposure keratopathy are possible complications of malar implant surgery.
- Published
- 1998
9. Orbital blow-out fractures: correlation of preoperative computed tomography and postoperative ocular motility.
- Author
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Harris GJ, Garcia GH, Logani SC, Murphy ML, Sheth BP, and Seth AK
- Subjects
- Humans, Orbital Fractures classification, Orbital Fractures physiopathology, Postoperative Period, Prognosis, Treatment Outcome, Vision, Binocular physiology, Visual Fields physiology, Eye Movements physiology, Orbital Fractures diagnostic imaging, Orbital Fractures surgery, Tomography, X-Ray Computed
- Abstract
Background/purpose: Although the management of orbital blow-out fractures was controversial for many years, refined imaging with computed tomography (CT) helped to narrow the poles of the debate. Many orbital surgeons currently recommend repair if fracture size portends late enophthalmos, or if diplopia has not substantially resolved within 2 weeks of the injury. While volumetric considerations have been generally well-served by this approach, ocular motility outcomes have been less than ideal. In one series, almost 50% of patients had residual diplopia 6 months after surgery. A fine network of fibrous septa that functionally unites the periosteum of the orbital floor, the inferior fibrofatty tissues, and the sheaths of the inferior rectus and oblique muscles was demonstrated by Koornneef. Entrapment between bone fragments of any of the components of this anatomic unit can limit ocular motility. Based on the pathogenesis of blow-out fractures, in which the fibrofatty-muscular complex is driven to varying degrees between bone fragments, some measure of soft tissue damage might be anticipated. Subsequent intrinsic fibrosis and contraction can tether globe movement, despite complete reduction of herniated orbital tissue from the fracture site. We postulated that the extent of this soft tissue damage might be estimated from preoperative imaging studies., Methods: Study criteria included: retrievable coronal CT scans; fractures of the orbital floor without rim involvement, with or without extension into the medial wall; preoperative diplopia; surgical repair by a single surgeon; complete release of entrapped tissues; and postoperative ocular motility outcomes documented with binocular visual fields (BVFs). Thirty patients met all criteria. The CT scans and BVFs were assessed by different examiners among the authors. Fractures were classified into 3 general categories and 2 subtypes to reflect the severity of soft tissue damage within each category. "Trap-door" injuries, in which bone fragments appeared to have almost perfectly realigned, were classified as type I fractures. In the I-A subtype, no orbital tissue was visible on the sinus side of the fracture line. In the I-B subtype, soft tissue with the radiodensity of orbital fat was visible within the maxillary sinus. In type II fractures, bone fragments were distracted and soft tissue was displaced between them. In the II-A subtype, soft tissue displacement was less than, or proportional to, bone fragment distraction. In the II-B subtype, soft tissue displacement was greater than bone fragment distraction. In type III fractures, displaced bone fragments surrounded displaced soft tissue in all areas. In the III-A subtype, soft tissue and bone were moderately displaced. In the III-B subtype, both were markedly displaced. Motility outcomes were quantified by measuring the vertical excursion in BVFs. The interval between trauma and surgical repair was also determined., Results: Among the 15 patients with a motility outcome in BVFs which was poorer than the median (86 degrees or less of single binocular vertical excursion), 4 patients (27%) had type A fractures; 11 patients (73%) had type B fractures. Among the 15 patients with a better outcome than the median (88 degrees or more), 10 patients (67%) had type A fractures; 5 patients (33%) had type B fractures. These differences became more defined as analysis moved away from the median. Among 5 patients with type B fractures and better than the median result in BVFs, 3 patients (60%) had surgical repair during the first week after injury. Among the 11 patients with type B fractures and less than the median result, 1 patient (9%) had repair during the first week., Conclusions: When the CT-depicted relationship between bone fragments and soft tissues is considered, a wide spectrum of injuries is subsumed under the rubric of blow-out fractures. In general, greater degrees of soft tissue incarceration or displacement, with presumably greater intrinsic damage and subsequent fibrosis, appear to result in poorer motility outcomes. Although this retrospective study does not conclusively prove its benefit, an urgent surgical approach to selected injuries should be considered.
- Published
- 1998
10. Bilateral, intraconal non-Hodgkin's lymphoma in a patient with acquired immunodeficiency syndrome.
- Author
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Logani S, Logani SC, Ali BH, and Goldberg RA
- Subjects
- Adult, Antineoplastic Agents therapeutic use, Combined Modality Therapy, Humans, Lymphoma, AIDS-Related therapy, Male, Orbit diagnostic imaging, Orbital Neoplasms therapy, Radiotherapy, Tomography, X-Ray Computed, Lymphoma, AIDS-Related pathology, Orbital Neoplasms pathology
- Published
- 1994
- Full Text
- View/download PDF
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