Search

Your search keyword '"Loh, Li Cher"' showing total 179 results
Start Over Author "Loh, Li Cher"

Refine your results

more »

more »

more »

more »

more »
179 results on '"Loh, Li Cher"'

1. Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study

Author

Hafizi, Hasan, Aliko, Anila, Bardhi, Donika, Tafa, Holta, Thanasi, Natasha, Mezini, Arian, Teferici, Alma, Todri, Dafina, Nikolla, Jolanda, Kazasi, Rezarta, Cherkaski, Hamid Hacene, Bengrait, Amira, Haddad, Tabarek, Zgaoula, Ibtissem, Ghit, Maamar, Roubhia, Abdelhamid, Boudra, Soumaya, Atoui, Feryal, Yakoubi, Randa, Benali, Rachid, Bencheikh, Abdelghani, Ait-Khaled, Nadia, Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Schirhofer, Lea, Islam, Akramul, Ahmed, Syed Masud, Islam, Shayla, Islam, Qazi Shafayetul, Mesbah-Ul-Haque, Chowdhury, Tridib Roy, Chatterjee, Sukantha Kumar, Mia, Dulal, Chandra Das, Shyamal, Rahman, Mizanur, Islam, Nazrul, Uddin, Shahaz, Islam, Nurul, Khatun, Luiza, Parvin, Monira, Khan, Abdul Awal, Islam, Maidul, Lawin, Herve, Kpangon, Arsene, Kpossou, Karl, Agodokpessi, Gildas, Ayelo, Paul, Fayomi, Benjamin, Mbatchou, Bertrand, Ashu, Atongno Humphrey, Tan, Wan C., Wang, Wen, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jin-ping, Zhou, Yumin, Jogi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Adegnika, Ayola Akim, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, SchwedaLinow, Alexandra, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Lovisa Gudmundsdottir, Gudmundsdottir, Sigrun, Gudmundsson, Gunnar, Rao, Mahesh, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Aquart-Stewart, Althea, Aikman, Akosua Francia, Sooronbaev, Talant M., Estebesova, Bermet M., Akmatalieva, Meerim, Usenbaeva, Saadat, Kydyrova, Jypara, Bostonova, Eliza, Sheraliev, Ulan, Marajapov, Nuridin, Toktogulova, Nurgul, Emilov, Berik, Azilova, Toktogul, Beishekeeva, Gulnara, Dononbaeva, Nasyikat, Tabyshova, Aijamal, Mortimer, Kevin, Nyapigoti, Wezzie, Mwangoka, Ernest, Kambwili, Mayamiko, Chipeta, Martha, Banda, Gloria, Mkandawire, Suzgo, Banda, Justice, Loh, Li-Cher, Rashid, Abdul, Sholehah, Siti, Benjelloun, Mohamed C., Nejjari, Chakib, Elbiaze, Mohamed, El Rhazi, Karima, Wouters, E.F.M., Wesseling, G.J., Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Nafees, Asaad A., Irfan, Muhammad, Fatmi, Zafar, Zahidie, Aysha, Shaukat, Natasha, Iqbal, Meesha, Idolor, Luisito F., de Guia, Teresita S., Francisco, Norberto A., Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Garcia, Gerard S., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Flordeliza, Simpao, Leander P., Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Barbara, Cristina, Rodrigues, Fatima, Dias, Herminia, Cardoso, Joao, Almeida, João, Matos, Maria Joao, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Al Ghobain, M., Alorainy, H., El-Hamad, E., Al Hajjaj, M., Hashi, A., Dela, R., Fanuncio, R., Doloriel, E., Marciano, I., Safia, L., Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gunasekera, Kirthi, Wickremasinghe, Rajitha, Elsony, Asma, Elsadig, Hana A., Osman, Nada Bakery, Noory, Bandar Salah, Mohamed, Monjda Awad, Akasha Ahmed Osman, Hasab Alrasoul, Moham ed Elhassan, Namarig, El Zain, Abdel Mu’is, Mohamaden, Marwa Mohamed, Khalifa, Suhaiba, Elhadi, Mahmoud, Hassan, Mohand, Abdelmonam, Dalia, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, SpetzNystrom, Ulrike, Hagg, Gunilla, Lund, GunMarie, Seemungal, Terence, Lutchmansingh, Fallon, Conyette, Liane, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Burney, Peter G.J., Gnatiuc, Louisa, Azar, Hadia, Patel, Jaymini, Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Dudhaiya, Risha, Buist, A. Sonia, McBurnie, Mary Ann, Vollmer, William M., Gillespie, Suzanne, Sullivan, Sean, Lee, Todd A., Weiss, Kevin B., Jensen, Robert L., Crapo, Robert, Enright, Paul, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Abozid, Hazim, Burney, Peter, Hartl, Sylvia, Breyer-Kohansal, Robab, Al Ghobain, Mohammed, Denguezli, Meriam, Loh, Li Cher, Paraguas, Stefanni Nonna, Franssen, Frits M.E., Mannino, David, Anand, Mahesh Padukudru, Buist, Sonia, El Sony, Asma, Breyer, Marie-Kathrin, Burghuber, Otto C., Wouters, Emiel F.M., and Amaral, Andre F.S.

Published
2024
Full Text
View/download PDF

2. The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disease (BOLD) study

Author

Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Barbara, Cristina, Buist, A. Sonia, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Erhabor, Gregory E., Franssen, Frits M. E., Al Ghobain, Mohammed, Gislason, Thorarinn, Janson, Christer, Kocabaş, Ali, Mannino, David, Marks, Guy, Mortimer, Kevin, Nafees, Asaad Ahmed, Obaseki, Daniel, Paraguas, Stefanni Nonna M., Loh, Li Cher, Rashid, Abdul, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C., Wouters, Emiel F. M., Abozid, Hazim, Mueller, Alexander, Burney, Peter, and Amaral, Andre F. S.

Published
2023
Full Text
View/download PDF

3. Small airways obstruction and its risk factors in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study

Author

Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Elsony, Asma, Franssen, Frits M E, Ghobain, Mohammed Al, Harrabi, Imed, Janson, Christer, Jõgi, Rain, Juvekar, Sanjay, Lawin, Herve, Mannino, David, Mortimer, Kevin, Nafees, Asaad Ahmed, Nielsen, Rune, Obaseki, Daniel, Paraguas, Stefanni Nonna M, Rashid, Abdul, Loh, Li-Cher, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C, Wouters, Emiel E F M, Barbara, Cristina, Gislason, Thorarinn, Gunasekera, Kirthi, Burney, Peter, and Amaral, Andre F S

Published
2023
Full Text
View/download PDF

5. “High-Risk” Clinical and Inflammatory Clusters in COPD of Chinese Descent

Author

Tiew, Pei Yee, Ko, Fanny Wai San, Narayana, Jayanth Kumar, Poh, Mau Ern, Xu, Huiying, Neo, Han Yee, Loh, Li-Cher, Ong, Choo Khoon, Mac Aogáin, Micheál, Tan, Jessica Han Ying, Kamaruddin, Nabilah Husna, Sim, Gerald Jiong Hui, Lapperre, Therese S., Koh, Mariko Siyue, Hui, David Shu Cheong, Abisheganaden, John Arputhan, Tee, Augustine, Tsaneva-Atanasova, Krasimira, and Chotirmall, Sanjay H.

Published
2020
Full Text
View/download PDF

6. Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study : a multinational cross-sectional study

Author

Abozid, Hazim, Patel, Jaymini, Burney, Peter, Hartl, Sylvia, Breyer-Kohansal, Robab, Mortimer, Kevin, Nafees, Asaad A., Al Ghobain, Mohammed, Welte, Tobias, Harrabi, Imed, Denguezli, Meriam, Loh, Li Cher, Rashid, Abdul, Gislason, Thorarinn, Barbara, Cristina, Cardoso, Joao, Rodrigues, Fatima, Seemungal, Terence, Obaseki, Daniel, Juvekar, Sanjay, Paraguas, Stefanni Nonna, Tan, Wan C., Franssen, Frits M. E., Mejza, Filip, Mannino, David, Janson, Christer, Cherkaski, Hamid Hacene, Anand, Mahesh Padukudru, Hafizi, Hasan, Buist, Sonia, Koul, Parvaiz A., Sony, Asmael, Breyer, Marie-Kathrin, Burghuber, Otto C., Wouters, Emiel F. M., Amaral, Andre F. S., Abozid, Hazim, Patel, Jaymini, Burney, Peter, Hartl, Sylvia, Breyer-Kohansal, Robab, Mortimer, Kevin, Nafees, Asaad A., Al Ghobain, Mohammed, Welte, Tobias, Harrabi, Imed, Denguezli, Meriam, Loh, Li Cher, Rashid, Abdul, Gislason, Thorarinn, Barbara, Cristina, Cardoso, Joao, Rodrigues, Fatima, Seemungal, Terence, Obaseki, Daniel, Juvekar, Sanjay, Paraguas, Stefanni Nonna, Tan, Wan C., Franssen, Frits M. E., Mejza, Filip, Mannino, David, Janson, Christer, Cherkaski, Hamid Hacene, Anand, Mahesh Padukudru, Hafizi, Hasan, Buist, Sonia, Koul, Parvaiz A., Sony, Asmael, Breyer, Marie-Kathrin, Burghuber, Otto C., Wouters, Emiel F. M., and Amaral, Andre F. S.

Abstract

Background Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a standardised protocol and definition. Methods We analysed cross-sectional data from 33,983 adults (>= 40 years), recruited between Jan 2, 2003 and Dec 26, 2016, in 41 sites (34 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We estimated the prevalence of chronic cough for each site accounting for sampling design. To identify risk factors, we conducted multivariable logistic regression analysis within each site and then pooled estimates using random -effects metaanalysis. We also calculated the population attributable risk (PAR) associated with each of the identifed risk factors. Findings The prevalence of chronic cough varied from 3% in India (rural Pune) to 24% in the United States of America (Lexington,KY). Chronic cough was more common among females, both current and passive smokers, those working in a dusty job, those with a history of tuberculosis, those who were obese, those with a low level of education and those with hypertension or airflow limitation. The most influential risk factors were current smoking and working in a dusty job. Interpretation Our findings suggested that the prevalence of chronic cough varies widely across sites in different world regions. Cigarette smoking and exposure to dust in the workplace are its major risk factors.

Published
2024
Full Text
View/download PDF

9. Cohort Profile : Burden of Obstructive Lung Disease (BOLD) study

Author

Amaral, Andre F S, Potts, James, Knox-Brown, Ben, Bagkeris, Emmanouil, Harrabi, Imed, Cherkaski, Hamid Hacene, Agarwal, Dhiraj, Juvekar, Sanjay, Anand, Mahesh Padukudru, Gislason, Thorarinn, Nafees, Asaad Ahmed, Mortimer, Kevin, Janson, Christer, Loh, Li Cher, Paraguas, Stefanni Nonna, Denguezli, Meriam, Al Ghobain, Mohammed, Mannino, David, Njoroge, Martin W, Devereux, Graham, Seemungal, Terence, Barbara, Cristina, Kocabaş, Ali, Ahmed, Rana, Aquart-Stewart, Althea, Studnicka, Michael, Welte, Tobias, Tan, Wan C, van Zyl-Smit, Richard N, Koul, Parvaiz, Garcia-Larsen, Vanessa, Minelli, Cosetta, Buist, A Sonia, Burney, Peter, Amaral, Andre F S, Potts, James, Knox-Brown, Ben, Bagkeris, Emmanouil, Harrabi, Imed, Cherkaski, Hamid Hacene, Agarwal, Dhiraj, Juvekar, Sanjay, Anand, Mahesh Padukudru, Gislason, Thorarinn, Nafees, Asaad Ahmed, Mortimer, Kevin, Janson, Christer, Loh, Li Cher, Paraguas, Stefanni Nonna, Denguezli, Meriam, Al Ghobain, Mohammed, Mannino, David, Njoroge, Martin W, Devereux, Graham, Seemungal, Terence, Barbara, Cristina, Kocabaş, Ali, Ahmed, Rana, Aquart-Stewart, Althea, Studnicka, Michael, Welte, Tobias, Tan, Wan C, van Zyl-Smit, Richard N, Koul, Parvaiz, Garcia-Larsen, Vanessa, Minelli, Cosetta, Buist, A Sonia, and Burney, Peter

Published
2023
Full Text
View/download PDF

12. Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study

Author

Ratanachina, Jate, primary, Amaral, Andre F.S., additional, De Matteis, Sara, additional, Lawin, Herve, additional, Mortimer, Kevin, additional, Obaseki, Daniel O., additional, Harrabi, Imed, additional, Denguezli, Meriam, additional, Wouters, Emiel F.M., additional, Janson, Christer, additional, Nielsen, Rune, additional, Gulsvik, Amund, additional, Cherkaski, Hamid Hacene, additional, Mejza, Filip, additional, Mahesh, Padukudru Anand, additional, Elsony, Asma, additional, Ahmed, Rana, additional, Tan, Wan, additional, Loh, Li Cher, additional, Rashid, Abdul, additional, Studnicka, Michael, additional, Nafees, Asaad A., additional, Seemungal, Terence, additional, Aquart-Stewart, Althea, additional, Al Ghobain, Mohammed, additional, Zheng, Jinping, additional, Juvekar, Sanjay, additional, Salvi, Sundeep, additional, Jogi, Rain, additional, Mannino, David, additional, Gislason, Thorarinn, additional, Buist, A. Sonia, additional, Cullinan, Paul, additional, and Burney, Peter, additional

Published
2022
Full Text
View/download PDF

13. Immunomodulators

Author

Loh, Li Cher, Barnes, Neil C., Parnham, Michael J., editor, Sampson, Anthony P., editor, and Church, Martin K., editor

Published
1999
Full Text
View/download PDF

14. Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

Author

Burney, Peter, Patel, Jaymini, Minelli, Cosetta, Gnatiuc, Louisa, Amaral, André F. S., Kocabaş, Ali, Cherkaski, Hamid Hacene, Gulsvik, Amund, Nielsen, Rune, Bateman, Eric, Jithoo, Anamika, Mortimer, Kevin, Sooronbaev, Talant M., Lawin, Hervé, Nejjari, Chakib, Elbiaze, Mohammed, El Rhazi, Karima, Zheng, Jin-Ping, Ran, Pixin, Welte, Tobias, Obaseki, Daniel, Erhabor, Gregory, Elsony, Asma, Osman, Nada Bakri, Ahmed, Rana, Nizankowska-Mogilnicka, Ewa, Mejza, Filip, Mannino, David M., Bárbara, Cristina, Wouters, Emiel F. M., Idolor, Luisito F., Loh, Li-Cher, Rashid, Abdul, Juvekar, Sanjay, Gislason, Thorarinn, Al Ghobain, Mohamed, Studnicka, Michael, Harrabi, Imed, Denguezli, Meriam, Koul, Parvaiz A., Jenkins, Christine, Marks, Guy, Jõgi, Rain, Hafizi, Hasan, Janson, Christer, Tan, Wan C., Aquart-Stewart, Althea, Mbatchou, Bertrand, Nafees, Asaad, Gunasekera, Kirthi, Seemungal, Terry, Padukudru Anand, Mahesh, Enright, Paul, Vollmer, William M., Blangiardo, Marta, Elfadaly, Fadlalla G., Buist, A. Sonia, Burney, Peter, Patel, Jaymini, Minelli, Cosetta, Gnatiuc, Louisa, Amaral, André F. S., Kocabaş, Ali, Cherkaski, Hamid Hacene, Gulsvik, Amund, Nielsen, Rune, Bateman, Eric, Jithoo, Anamika, Mortimer, Kevin, Sooronbaev, Talant M., Lawin, Hervé, Nejjari, Chakib, Elbiaze, Mohammed, El Rhazi, Karima, Zheng, Jin-Ping, Ran, Pixin, Welte, Tobias, Obaseki, Daniel, Erhabor, Gregory, Elsony, Asma, Osman, Nada Bakri, Ahmed, Rana, Nizankowska-Mogilnicka, Ewa, Mejza, Filip, Mannino, David M., Bárbara, Cristina, Wouters, Emiel F. M., Idolor, Luisito F., Loh, Li-Cher, Rashid, Abdul, Juvekar, Sanjay, Gislason, Thorarinn, Al Ghobain, Mohamed, Studnicka, Michael, Harrabi, Imed, Denguezli, Meriam, Koul, Parvaiz A., Jenkins, Christine, Marks, Guy, Jõgi, Rain, Hafizi, Hasan, Janson, Christer, Tan, Wan C., Aquart-Stewart, Althea, Mbatchou, Bertrand, Nafees, Asaad, Gunasekera, Kirthi, Seemungal, Terry, Padukudru Anand, Mahesh, Enright, Paul, Vollmer, William M., Blangiardo, Marta, Elfadaly, Fadlalla G., and Buist, A. Sonia

Abstract

Rationale: The Global Burden of Disease program identified smoking and ambient and household air pollution as the main drivers of death and disability from chronic obstructive pulmonary disease (COPD). Objectives: To estimate the attributable risk of chronic airflow obstruction (CAO), a quantifiable characteristic of COPD, due to several risk factors. Methods: The Burden of Obstructive Lung Disease study is a cross-sectional study of adults, aged ≥40, in a globally distributed sample of 41 urban and rural sites. Based on data from 28,459 participants, we estimated the prevalence of CAO, defined as a postbronchodilator FEV1-to-FVC ratio less than the lower limit of normal, and the relative risks associated with different risk factors. Local relative risks were estimated using a Bayesian hierarchical model borrowing information from across sites. From these relative risks and the prevalence of risk factors, we estimated local population attributable risks. Measurements and Main Results: The mean prevalence of CAO was 11.2% in men and 8.6% in women. The mean population attributable risk for smoking was 5.1% in men and 2.2% in women. The next most influential risk factors were poor education levels, working in a dusty job for ≥10 years, low body mass index, and a history of tuberculosis. The risk of CAO attributable to the different risk factors varied across sites. Conclusions: Although smoking remains the most important risk factor for CAO, in some areas, poor education, low body mass index, and passive smoking are of greater importance. Dusty occupations and tuberculosis are important risk factors at some sites.

Published
2021
Full Text
View/download PDF

15. Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

Author

Burney, Peter, primary, Patel, Jaymini, additional, Minelli, Cosetta, additional, Gnatiuc, Louisa, additional, Amaral, André F. S., additional, Kocabaş, Ali, additional, Cherkaski, Hamid Hacene, additional, Gulsvik, Amund, additional, Nielsen, Rune, additional, Bateman, Eric, additional, Jithoo, Anamika, additional, Mortimer, Kevin, additional, Sooronbaev, Talant M., additional, Lawin, Hervé, additional, Nejjari, Chakib, additional, Elbiaze, Mohammed, additional, El Rhazi, Karima, additional, Zheng, Jin-Ping, additional, Ran, Pixin, additional, Welte, Tobias, additional, Obaseki, Daniel, additional, Erhabor, Gregory, additional, Elsony, Asma, additional, Osman, Nada Bakri, additional, Ahmed, Rana, additional, Nizankowska-Mogilnicka, Ewa, additional, Mejza, Filip, additional, Mannino, David M., additional, Bárbara, Cristina, additional, Wouters, Emiel F. M., additional, Idolor, Luisito F., additional, Loh, Li-Cher, additional, Rashid, Abdul, additional, Juvekar, Sanjay, additional, Gislason, Thorarinn, additional, Al Ghobain, Mohamed, additional, Studnicka, Michael, additional, Harrabi, Imed, additional, Denguezli, Meriam, additional, Koul, Parvaiz A., additional, Jenkins, Christine, additional, Marks, Guy, additional, Jõgi, Rain, additional, Hafizi, Hasan, additional, Janson, Christer, additional, Tan, Wan C., additional, Aquart-Stewart, Althea, additional, Mbatchou, Bertrand, additional, Nafees, Asaad Ahmed, additional, Gunasekera, Kirthi, additional, Seemungal, Terry, additional, Anand, Mahesh Padukudru, additional, Enright, Paul, additional, Vollmer, William M., additional, Blangiardo, Marta, additional, Elfadaly, Fadlalla G., additional, Buist, A. Sonia, additional, Aliko, Anila, additional, Bardhi, Donika, additional, Tafa, Holta, additional, Thanasi, Natasha, additional, Mezini, Arian, additional, Teferici, Alma, additional, Todri, Dafina, additional, Nikolla, Jolanda, additional, Kazasi, Rezarta, additional, Bengrait, Amira, additional, Haddad, Tabarek, additional, Zgaoula, Ibtissem, additional, Ghit, Maamar, additional, Roubhia, Abdelhamid, additional, Boudra, Soumaya, additional, Atoui, Feryal, additional, Yakoubi, Randa, additional, Benali, Rachid, additional, Bencheikh, Abdelghani, additional, Ait-Khaled, Nadia, additional, Bird, Tessa, additional, Espinel, Paola, additional, Hardaker, Kate, additional, Toelle, Brett, additional, Dawes, Torkil, additional, Lamprecht, Bernd, additional, Schirhofer, Lea, additional, Islam, Akramul, additional, Ahmed, Syed Masud, additional, Islam, Shayla, additional, Islam, Qazi Shafayetul, additional, Chowdhury, Tridib Roy, additional, Chatterjee, Sukantha Kumar, additional, Mia, Dulal, additional, Das, Shyamal Chandra, additional, Rahman, Mizanur, additional, Islam, Nazrul, additional, Uddin, Shahaz, additional, Islam, Nurul, additional, Khatun, Luiza, additional, Parvin, Monira, additional, Khan, Abdul Awal, additional, Islam, Maidul, additional, Lawin, Herve, additional, Kpangon, Arsene, additional, Kpossou, Karl, additional, Agodokpessi, Gildas, additional, Ayelo, Paul, additional, Fayomi, Benjamin, additional, Ashu, Atongno Humphrey, additional, Wang, Wen, additional, Zhong, NanShan, additional, Liu, Shengming, additional, Lu, Jiachun, additional, Wang, Dali, additional, Zheng, Jin-ping, additional, Zhou, Yumin, additional, Laja, Hendrik, additional, Ulst, Katrin, additional, Zobel, Vappu, additional, Lill, Toomas-Julius, additional, Adegnika, Ayola Akim, additional, Bodemann, Isabelle, additional, Geldmacher, Henning, additional, Schweda-Linow, Alexandra, additional, Benedikdtsdottir, Bryndis, additional, Jörundsdottir, Kristin, additional, Gudmundsdottir, Lovisa, additional, Gudmundsdottir, Sigrun, additional, Gudmundsson, Gunnar, additional, Rao, Mahesh, additional, Malik, Sajjad, additional, Hakim, Nissar A., additional, Khan, Umar Hafiz, additional, Chowgule, Rohini, additional, Shetye, Vasant, additional, Raphael, Jonelle, additional, Almeda, Rosel, additional, Tawde, Mahesh, additional, Tadvi, Rafiq, additional, Katkar, Sunil, additional, Kadam, Milind, additional, Dhanawade, Rupesh, additional, Ghurup, Umesh, additional, Hirve, Siddhi, additional, Sambhudas, Somnath, additional, Chaidhary, Bharat, additional, Tambe, Meera, additional, Pingale, Savita, additional, Umap, Arati, additional, Umap, Archana, additional, Shelar, Nitin, additional, Devchakke, Sampada, additional, Chaudhary, Sharda, additional, Bondre, Suvarna, additional, Walke, Savita, additional, Gawhane, Ashleshsa, additional, Sapkal, Anil, additional, Argade, Rupali, additional, Gaikwad, Vijay, additional, Salvi, Sundeep, additional, Brashier, Bill, additional, Londhe, Jyoti, additional, Madas, Sapna, additional, Aikman, Akosua Francia, additional, Estebesova, Bermet M., additional, Akmatalieva, Meerim, additional, Usenbaeva, Saadat, additional, Kydyrova, Jypara, additional, Bostonova, Eliza, additional, Sheraliev, Ulan, additional, Marajapov, Nuridin, additional, Toktogulova, Nurgul, additional, Emilov, Berik, additional, Azilova, Toktogul, additional, Beishekeeva, Gulnara, additional, Dononbaeva, Nasyikat, additional, Tabyshova, Aijamal, additional, Nyapigoti, Wezzie, additional, Mwangoka, Ernest, additional, Kambwili, Mayamiko, additional, Chipeta, Martha, additional, Banda, Gloria, additional, Mkandawire, Suzgo, additional, Banda, Justice, additional, Sholehah, Siti, additional, Benjelloun, Mohamed C., additional, Elbiaze, Mohamed, additional, Wouters, E. F. M., additional, Wesseling, G. J., additional, Awopeju, Olayemi, additional, Adewole, Olufemi, additional, Endresen, Tina, additional, Svendsen, Lene, additional, Nafees, Asaad A., additional, de Guia, Teresita S., additional, Francisco, Norberto A., additional, Roa, Camilo C., additional, Ayuyao, Fernando G., additional, Tady, Cecil Z., additional, Tan, Daniel T., additional, Banal-Yang, Sylvia, additional, Balanag, Vincent M., additional, Reyes, Maria Teresita N., additional, Dantes, Renato. B., additional, Dantes, Renato B., additional, Amarillo, Lourdes, additional, Berratio, Lakan U., additional, Fernandez, Lenora C., additional, Garcia, Gerard S., additional, Naval, Sullian S., additional, Reyes, Thessa, additional, Sanchez, Ma. Flordeliza, additional, Simpao, Leander P., additional, Frey, Jakub, additional, Harat, Rafal, additional, Nastalek, Pawel, additional, Pajak, Andrzej, additional, Skucha, Wojciech, additional, Szczeklik, Andrzej, additional, Twardowska, Magda, additional, Rodrigues, Fátima, additional, Dias, Hermínia, additional, Cardoso, João, additional, Almeida, João, additional, Matos, Maria João, additional, Simão, Paula, additional, Santos, Moutinho, additional, Ferreira, Reis, additional, Al Ghobain, M., additional, Alorainy, H., additional, El-Hamad, E., additional, Al Hajjaj, M., additional, Hashi, A., additional, Dela, R., additional, Fanuncio, R., additional, Doloriel, E., additional, Marciano, I., additional, Safia, L., additional, Adams, Desiree, additional, Barnes, Edward, additional, Freeman, Jasper, additional, Hayes, Anton, additional, Hlengwa, Sipho, additional, Johannisen, Christine, additional, Koopman, Mariana, additional, Louw, Innocentia, additional, Ludick, Ina, additional, Olckers, Alta, additional, Ryck, Johanna, additional, Storbeck, Janita, additional, Wickremasinghe, Rajitha, additional, Elsadig, Hana A., additional, Osman, Nada Bakery, additional, Noory, Bandar Salah, additional, Mohamed, Monjda Awad, additional, Osman, Hasab Alrasoul Akasha Ahmed, additional, ed Elhassan, Namarig Moham, additional, Mu‘is El Zain, Abdel, additional, Mohamaden, Marwa Mohamed, additional, Khalifa, Suhaiba, additional, Elhadi, Mahmoud, additional, Hassan, Mohand, additional, Abdelmonam, Dalia, additional, Olafsdottir, Inga Sif, additional, Nisser, Katarina, additional, Spetz-Nyström, Ulrike, additional, Hägg, Gunilla, additional, Lund, Gun-Marie, additional, Seemungal, Terence, additional, Lutchmansingh, Fallon, additional, Conyette, Liane, additional, Denguezli, Myriam, additional, Tabka, Zouhair, additional, Daldoul, Hager, additional, Boukheroufa, Zaki, additional, Chouikha, Firas, additional, Khalifa, Wahbi Belhaj, additional, Hancioglu, Attila, additional, Hanta, Ismail, additional, Kuleci, Sedat, additional, Turkyilmaz, Ahmet Sinan, additional, Umut, Sema, additional, Unalan, Turgay, additional, Burney, Peter G. J., additional, Azar, Hadia, additional, Amor, Caron, additional, Potts, James, additional, Tumilty, Michael, additional, McLean, Fiona, additional, Dudhaiya, Risha, additional, McBurnie, Mary Ann, additional, Gillespie, Suzanne, additional, Sullivan, Sean, additional, Lee, Todd A., additional, Weiss, Kevin B., additional, Jensen, Robert L., additional, Crapo, Robert, additional, Cain, John, additional, Copeland, Rebecca, additional, Hazen, Dana, additional, and Methvin, Jennifer, additional

Published
2021
Full Text
View/download PDF

28. A novel CT-emphysema index/FEV1 approach of phenotyping COPD to predict mortality

Author

Loh,Li-Cher, Ong,Choo-Khoon, Koo,Hyun Jung, Lee,Sang Min, Lee,Jae-Seung, Oh,Yeon-Mok, Seo,Joon Beom, and Lee,Sang-Do

Subjects
International Journal of Chronic Obstructive Pulmonary Disease, respiratory tract diseases
Abstract

Li-Cher Loh,1 Choo-Khoon Ong,1 Hyun-Jung Koo,2 Sang Min Lee,2 Jae-Seung Lee,3 Yeon-Mok Oh,3 Joon-Beom Seo,2 Sang-Do Lee3 1Department of Medicine, RCSI & UCD Malaysia Campus, Penang, Malaysia; 2Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 3Department of Pulmonary and Critical Care Medicine, and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea Background: COPD-associated mortality was examined using a novel approach of phenotyping COPD based on computed tomography (CT)-emphysema index from quantitative CT (QCT) and post-bronchodilator (BD) forced expiratory volume in 1 second (FEV1) in a local Malaysian cohort.Patients and methods: Prospectively collected data of 112 eligible COPD subjects (mean age, 67 years; male, 93%; mean post-BD FEV1, 45.7%) was available for mortality analysis. Median follow-up time was 1,000 days (range, 60–1,400). QCT and clinicodemographic data were collected at study entry. Based on CT-emphysema index and post-BD FEV1% predicted, subjects were categorized into “emphysema-dominant,” “airway-dominant,” “mild mixed airway-emphysema,” and “severe mixed airway-emphysema” diseases.Results: Sixteen patients (14.2%) died of COPD-associated causes. There were 29 (25.9%) “mild mixed,” 23 (20.5%) “airway-dominant,” 15 (13.4%) “emphysema-dominant,” and 45 (40.2%) “severe mixed” cases. “Mild mixed” disease was proportionately more in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Group A, while “severe mixed” disease was proportionately more in GOLD Groups B and D. Kaplan–Meier survival estimates showed increased mortality risk with “severe mixed” disease (log rank test, p=0.03) but not with GOLD groups (p=0.08). Univariate Cox proportionate hazard analysis showed that age, body mass index, long-term oxygen therapy, FEV1, forced volume capacity, COPD Assessment Test score, modified Medical Research Council score, St Georges’ Respiratory Questionnaire score, CT-emphysema index, and “severe mixed” disease (vs “mild mixed” disease) were associated with mortality. Multivariate Cox analysis showed that age, body mass index, and COPD Assessment Test score remain independently associated with mortality.Conclusion: “Severe mixed airway-emphysema” disease may predict COPD-associated mortality. Age, body mass index, and COPD Assessment Test score remain as key mortality risk factors in our cohort. Keywords: computed tomography, emphysema, forced expiratory volume, COPD, mortality

Published
2018

29. Chronic Obstructive Pulmonary Disease (COPD) in patients of Chinese ethnicity reveal clinically relevant phenotypes

Author

Tiew, Pei yee, primary, Ko, Fanny Wai San, additional, Xu, Huiying, additional, Poh, Mau Ern, additional, Narayana, Jayanth Kumar, additional, Sim, Gerald Jiong Hui, additional, Neo, Han Yee, additional, Loh, Li-Cher, additional, Ong, Choo Khoon, additional, Tan, Jessica Han Ying, additional, Kamaruddin, N H, additional, Lapperre, Therese Sophie, additional, Abisheganaden, John Arputhan, additional, Tee, Augustine Kim Huat, additional, and Chotirmall, Sanjay Haresh, additional

Published
2019
Full Text
View/download PDF

30. Airflow obstruction and use of solid fuels for cooking or heating: BOLD results

Author

Amaral, André F. S., Patel, Jaymini, Kato, Bernet S, Obaseki, Daniel O, Lawin, Hervé, Tan, Wan C, Juvekar, Sanjay K, Harrabi, Imed, Studnicka, Michael, Wouters, Emiel F.M., Loh, Li-Cher, Bateman, Eric D., Mortimer, Kevin, Buist, A. Sonia, Burney, Peter G.J., and Wellcome Trust

Subjects
wa_754, Low income countries, solid fuels (biomass), Respiratory System, wa_395, airflow obstruction, wa_795, chronic obstructive pulmonary disease, LOWER LIMIT, BIOMASS SMOKE, Critical Care Medicine, POLLUTION, BOLD Collaborative Research Group, low-income countries, General & Internal Medicine, YOUNG-ADULTS, PULMONARY-DISEASE, COPD, Biomass, CHIMNEY STOVE INTERVENTION, 11 Medical and Health Sciences, Science & Technology, REFERENCE VALUES, wf_20, respiratory tract diseases, Airway Obstruction, CHRONIC-BRONCHITIS, NEVER-SMOKERS, RISK-FACTORS, Life Sciences & Biomedicine, wf_600
Abstract

Rationale: \ud Evidence supporting the association of COPD or airflow obstruction with use of solid fuels is conflicting and inconsistent.\ud \ud Objective: \ud To assess the association of airflow obstruction with self-reported use of solid fuels for cooking or heating.\ud \ud Methods: \ud We analysed 18,554 adults from the BOLD study, who had provided acceptable post-bronchodilator spirometry measurements and information on use of solid fuels. The association of airflow obstruction with use of solid fuels for cooking or heating was assessed by sex, within each site, using regression analysis. Estimates were stratified by national income and meta-analysed. We carried out similar analyses for spirometric restriction, chronic cough and chronic phlegm.\ud \ud Measurements and main results: \ud We found no association between airflow obstruction and use of solid fuels for cooking or heating (ORmen=1.20, 95%CI 0.94-1.53; ORwomen=0.88, 95%CI 0.67-1.15). This was true for low/middle and high income sites. Among never smokers there was also no evidence of an association of airflow obstruction with use of solid fuels (ORmen=1.00, 95%CI 0.57-1.76; ORwomen=1.00, 95%CI 0.76-1.32). Overall, we found no association of spirometric restriction, chronic cough or chronic phlegm with the use of solid fuels. However, we found that chronic phlegm was more likely to be reported among female never smokers and those who had been exposed for ≥20 years.\ud \ud Conclusion: \ud Airflow obstruction assessed from post-bronchodilator spirometry was not associated with use of solid fuels for cooking or heating.

Published
2017

37. Airflow Obstruction and Use of Solid Fuels for Cooking or Heating: BOLD Results.

Author

Amaral, André F. S., Patel, Jaymini, Kato, Bernet S., Obaseki, Daniel O., Lawin, Hervé, Tan, Wan C., Juvekar, Sanjay K., Harrabi, Imed, Studnicka, Michael, Wouters, Emiel F. M., Li-Cher Loh, Bateman, Eric D., Mortimer, Kevin, Buist, A. Sonia, Burney, Peter G. J., Loh, Li-Cher, and BOLD Collaborative Research Group

Abstract

Rationale: Evidence supporting the association of COPD or airflow obstruction with use of solid fuels is conflicting and inconsistent.Objective: To assess the association of airflow obstruction with self-reported use of solid fuels for cooking or heating.Methods: We analysed 18,554 adults from the BOLD study, who had provided acceptable post-bronchodilator spirometry measurements and information on use of solid fuels. The association of airflow obstruction with use of solid fuels for cooking or heating was assessed by sex, within each site, using regression analysis. Estimates were stratified by national income and meta-analysed. We carried out similar analyses for spirometric restriction, chronic cough and chronic phlegm.Measurements and Main Results: We found no association between airflow obstruction and use of solid fuels for cooking or heating (ORmen=1.20, 95%CI 0.94-1.53; ORwomen=0.88, 95%CI 0.67-1.15). This was true for low/middle and high income sites. Among never smokers there was also no evidence of an association of airflow obstruction with use of solid fuels (ORmen=1.00, 95%CI 0.57-1.76; ORwomen=1.00, 95%CI 0.76-1.32). Overall, we found no association of spirometric restriction, chronic cough or chronic phlegm with the use of solid fuels. However, we found that chronic phlegm was more likely to be reported among female never smokers and those who had been exposed for ≥20 years.Conclusion: Airflow obstruction assessed from post-bronchodilator spirometry was not associated with use of solid fuels for cooking or heating. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

38. Impact of a Spreading Epidemic on Medical Students

Author

Loh, Li-Cher, Ali, Anita Mohd, Ang, Ter-Hoay, and Chelliah, Ambiga

Subjects
education, Original Article
Abstract

The emergence of severe acute respiratory syndrome (SARS) had caused fear and anxiety of unprecedented proportion. To examine the impact of SARS on the medical students in a private medical university, a self-reporting questionnaire study was carried out to assess the factual knowledge, anxiety level and perception of the crisis, among the students. The two-week study (between 12 and 23 May, 2003) was carried out three weeks after the first reported SARS-related death in Malaysia. Ninety-one Phase I (junior) and 113 Phase II (senior) students completed the questionnaires. A large majority of students of Phase I and II were correct in their factual knowledge and were sensible in their perception of the future and the handling of the crisis by government(s). However, phase 1 students expressed significantly greater degree of anxiety compared to Phase II in relation to attendance and personal protection in hospital, and in meeting people coughing in public places. The lesser degree of anxiety expressed by phase II senior students may be due in part, to a more realistic assessment of SARS risk brought about by maturity, time spent in hospital and interaction with clinical lecturers and medical staff.

Published
2005

39. Correcting Metered-Dose Inhaler Technique vs Switching to Turbohaler in Asthmatic Patients a Study on ‘Real-Life’ Effectiveness

Author

Loh, Li-Cher and Ngor Teh, Pek

Subjects
integumentary system, Original Article
Abstract

In practice, asthmatic patients whose metered-dose inhaler (MDI) technique is inefficient are either corrected or changed to dry powder breath-actuated or spacer device that is easier to handle. Based on 'real life clinic circumstances', we studied 15 symptomatic asthmatic patients whose MDI techniques were inefficient that either received correction in their technique (n=9) or were changed to turbohaler (n=6). For comparison, we also studied a similar group of symptomatic asthmatic patients (n=6) with appropriate MDI techniques that were treated by doubling of inhaled corticosteroid (ICS) dose. After 4 weeks, FEV(1) and symptom scores in the turbohaler group was significantly improved from baseline but not in the corrected MDI group. The group whose ICS dose was doubled also showed significant improvement in symptom scores but not in FEV(1). We question the benefit gained by correcting MDI technique in some asthmatic patients compared to that of switching over to more user-friendly devices such as turbohaler. In our study, the improvement observed with turbohaler appears to be more than a mere doubling of drug delivery to the lungs and may relate to the recognized greater consistency of drug delivery by turbohaler compared to MDI device.

Published
2004

40. Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities

Author

Oh,Yeon-Mok, Bhome,Arvind B, Boonsawat,Watchara, Gunasekera,Kirthi Dias, Madegedara,Dushantha, Idolor,Luisito, Roa,Camilo, Kim,Woo Jin, Kuo,Han-Pin, Wang,Chun-Hua, Lan,Le Thi Tuyet, Loh,Li-Cher, Ong,Choo-Khoon, Ng,Alan, Nishimura,Masaharu, Makita,Hironi, Silverman,Edwin K, Lee,Jae Seung, Yang,Ting, Lin,Yingxiang, Wang,Chen, Lee,Sang-Do, Oh,Yeon-Mok, Bhome,Arvind B, Boonsawat,Watchara, Gunasekera,Kirthi Dias, Madegedara,Dushantha, Idolor,Luisito, Roa,Camilo, Kim,Woo Jin, Kuo,Han-Pin, Wang,Chun-Hua, Lan,Le Thi Tuyet, Loh,Li-Cher, Ong,Choo-Khoon, Ng,Alan, Nishimura,Masaharu, Makita,Hironi, Silverman,Edwin K, Lee,Jae Seung, Yang,Ting, Lin,Yingxiang, Wang,Chen, and Lee,Sang-Do

Abstract

Yeon-Mok Oh,1 Arvind B Bhome,2 Watchara Boonsawat,3 Kirthi Dias Gunasekera,4 Dushantha Madegedara,5 Luisito Idolor,6 Camilo Roa,6 Woo Jin Kim,7 Han-Pin Kuo,8 Chun-Hua Wang,8 Le Thi Tuyet Lan,9 Li-Cher Loh,10 Choo-Khoon Ong,10 Alan Ng,11 Masaharu Nishimura,12 Hironi Makita,12 Edwin K Silverman,13 Jae Seung Lee,1 Ting Yang,14 Yingxiang Lin,14 Chen Wang,14 Sang-Do Lee1  1Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 2Department of Pulmonary and Critical Care, "Friends of the Breathless" Foundation, Pune, India; 3Department of Medicine, Khon Kaen University, Khon Kaen, Thailand; 4Central Chest Clinic, Colombo and National Hospital of Sri Lanka; 5Respiratory Disease Treatment Unit and Teaching Hospital Kandy, Sri Lanka; 6Section of Respiratory Services and Physical Therapy and Rehabilitation Lung Center of the Philippines, Quezon City, Philippines; 7Department of Internal Medicine, Kangwon National University, Kang Won, Korea; 8Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan; 9Respiratory Care Center, University Medical Center Ho Chi Minh City, Vietnam; 10Department of Medicine, Penang Medical College, Penang, Malaysia; 11Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore; 12Division of Respiratory Medicine, Department of Internal Medicine, Hokkaido University Hospital, Sapporo, Japan; 13Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; 14Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, ChinaAll authors made an equal contribution to this studyBackground and objectives: Chronic obstructive pulmonary disease (COPD) is responsible for significant morbidity and mortality worldwide. We evaluated the characteristics of stable COPD

Published
2013

41. Satisfaction levels and asthma control amongst Malaysian asthmatic patients on budesonide/formoterol maintenance and reliever therapy: experience in a real-life setting

Author

Abdul Manap,Roslina, Loh,Li Cher, Ismail ,Tengku Saifudin Tengku, Muttalif,Abdul Razak, Simon ,George Kutty, Beng Hong Toh,Rosalind, Razali Norhaya,Mohd, Md Tarekh,Noor Aliza, Hashim ,Che Wan Aminuddin, Rani ,Mohammad Fauzi Abdul, Mahayiddin,Aziah Ahmad, Abdul Manap,Roslina, Loh,Li Cher, Ismail ,Tengku Saifudin Tengku, Muttalif,Abdul Razak, Simon ,George Kutty, Beng Hong Toh,Rosalind, Razali Norhaya,Mohd, Md Tarekh,Noor Aliza, Hashim ,Che Wan Aminuddin, Rani ,Mohammad Fauzi Abdul, and Mahayiddin,Aziah Ahmad

Abstract

Roslina Abdul Manap,1 Li Cher Loh,2 Tengku Saifudin Tengku Ismail,3 Abdul Razak Muttalif,4 George Kutty Simon,5 Rosalind Beng Hong Toh,6 Mohd Razali Norhaya,7 Noor Aliza Md Tarekh,8 Che Wan Aminuddin Hashim,9 Mohammad Fauzi Abdul Rani,10 Aziah Ahmad Mahayiddin111Department of Medicine, UniversitiKebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia; 2Department of Medicine, Penang Medical College, Penang, Malaysia; 3Department of Medicine, Faculty of Medicine UniversitiInstitutTeknologi MARA, Selangor, Malaysia; 4Department of Respiratory Medicine, Penang Hospital, Penang, Malaysia; 5Department of Respiratory Medicine, Hospital SultanahBahiyah, Alor Star, Kedah, Malaysia; 6Hospital Ipoh, Ipoh, Malaysia; 7Hospital SultanahNurZahirah, Kuala Terengganu, Malaysia; 8Hospital SultanahAminah, Johor Bahru, Malaysia; 9Hospital UniversitiSains Malaysia, Kelantan, Malaysia; 10Hospital TengkuAmpuanAfzan, Kuantan, Malaysia; 11Institute of Respiratory Medicine, Kuala Lumpur, MalaysiaBackground: Budesonide/formoterol used for both maintenance and reliever therapy has been shown to benefit patients with persistent asthma. We evaluated patient satisfaction and asthma control among Malaysian patients prescribed budesonide/formoterol as single maintenance and reliever therapy in a real-life clinical practice.Methods: Adult patients diagnosed with partially controlled or uncontrolled asthma were recruited in a 6-month, prospective, open-label study involving ten hospital-based chest clinics in Malaysia. Patients were prescribed one or two inhalations of budesonide/formoterol Turbuhaler (160/4.5 µg per inhalation) twice daily as maintenance therapy and additional inhalation as reliever therapy. Maintenance doses were decided by physicians based on Global Initiative for Asthma-defined treatment objectives. The primary outcome measure was the change in mean Satisfaction with Asthma Treatment Questionnaire (SATQ) scores from baseline to an average of 3 months and 6 months. S

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results