Search

Your search keyword '"Long, Xianwen"' showing total 17 results
Start Over Author "Long, Xianwen"
17 results on '"Long, Xianwen"'

13. Total Synthesis of Asperchalasine A.

Author

Long, Xianwen, Ding, Yiming, Wu, Hai, and Deng, Jun

Subjects
*HORNER-Emmons reaction, *DIELS-Alder reaction, *RING formation (Chemistry), *BIOMIMETIC synthesis, *NATURAL products
Abstract

Here we briefly reviewed recent synthetic progress toward cytochalasan trimer, asperchalasine A by Tang, Trauner and our group. This process features a highly stereoselective intermolecular Diels–Alder reaction and a HWE or RCM macrocyclization to establish the key monomer aspochalasin B. A late-stage biomimetic oxidative dearomatization of triphenol and subsequent [5+2] cycloaddition cascade furnished asperchalasine A. We anticipate that this key reaction could also be used for the synthesis of other merocytochalasans, and provide some insight into the biosynthetic connections of merocytochalasans. 1 Introduction 2 Total Synthesis of Aspochalasin B 3 Total Synthesis of Asperchalasine A 4 Conclusions [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

16. Total Synthesis of Asperchalasines A, D, E, and H.

Author

Ding, Yiming, Deng, Jun, and Long, Xianwen

Subjects
BIOSYNTHESIS, DIMERS, DIELS-Alder reaction, STEREOSELECTIVE reactions, FUNGAL metabolites
Abstract

Copyright of Angewandte Chemie is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
Full Text
View/download PDF

17. Total Synthesis of (-)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone.

Author

Long Y, Ding Y, Wu H, Qu C, Liang H, Zhang M, Zhao X, Long X, Wang S, Puno PT, and Deng J

Abstract

The first copper-catalyzed intermolecular [5+2] homodimerization of hydroxy p-quinone is presented, furnishing bicyclo[3.2.1]octadienone core structures in typically good yields and excellent diastereoselectivities. Applying this synthetic approach enables a concise nine-step total synthesis of (-)-perezoperezone from commercially available 3,5-dimethoxytoluene., (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results