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22 results on '"Lowney, Yvette W."'

9. Predicting oral relative bioavailability of arsenic in soil from in vitro bioaccessibility

Author

Diamond, Gary L., primary, Bradham, Karen D., additional, Brattin, William J., additional, Burgess, Michele, additional, Griffin, Susan, additional, Hawkins, Cheryl A., additional, Juhasz, Albert L., additional, Klotzbach, Julie M., additional, Nelson, Clay, additional, Lowney, Yvette W., additional, Scheckel, Kirk G., additional, and Thomas, David J., additional

Published
2016
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10. Variability of bioaccessibility results using seventeen different methods on a standard reference material, NIST 2710

Author

Koch, Iris, primary, Reimer, Kenneth J., additional, Bakker, Martine I., additional, Basta, Nicholas T., additional, Cave, Mark R., additional, Denys, Sébastien, additional, Dodd, Matt, additional, Hale, Beverly A., additional, Irwin, Rob, additional, Lowney, Yvette W., additional, Moore, Margo M., additional, Paquin, Viviane, additional, Rasmussen, Pat E., additional, Repaso-Subang, Theresa, additional, Stephenson, Gladys L., additional, Siciliano, Steven D., additional, Wragg, Joanna, additional, and Zagury, Gerald J., additional

Published
2013
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13. Importance of Considering the Framework Principles in Risk Assessment for Metals

Author

Menzie, Charles A., primary, Ziccardi, Linda M., additional, Lowney, Yvette W., additional, Fairbrother, Anne, additional, Shock, Scott S., additional, Tsuji, Joyce S., additional, Hamai, Diem, additional, Proctor, Deborah, additional, Henry, Elizabeth, additional, Su, Steave H., additional, Kierski, Michael W., additional, McArdle, Margaret E., additional, and Yost, Lisa J., additional

Published
2009
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21. In Vivo Percutaneous Absorption of Arsenic from Waterand CCA-Treated Wood Residue.

Author

Wester, Ronald C., Xiaoying Hui, Barbadillo, Sherry, Maibach, Howard I., Lowney, Yvette W., Schoof, Rosalind A., Holm, Stewart E., and Ruby, Michael V.

Subjects
ARSENIC, WOOD, RESEARCH, ANIMALS, MONKEYS, SUBSTRATES (Materials science), SURFACES (Technology)
Abstract

This study was conducted to evaluate the dermal absorption of arsenic from residues present on the surface of wood preserved with chromated copper arsenate (CCA). The research reported herein used methods parallel to those of earlier research on the dermal absorption of radiolabeled arsenic (R. C. Wester et al., 1993, Fund. Appl. Toxicol. 20, 336–340), with modifications to allow use of environmental matrices that are not radiolabeled. These modifications include the surface area of application and dietary intake of arsenic, thus maximizing the potential for detection of dermally absorbed arsenic in exposed animals above diet-associated background levels of exposure. Two forms of arsenic were administered in this work. The first, arsenic in solution, was applied to the skin of monkeys to calibrate the model against prior absorption research and to serve as the basis of comparison for absorption of arsenic from CCA-treated wood residues. The second substrate was residue that resides on the surface of CCA-treated wood. Results from this research indicate that this study methodology can be used to evaluate dermally absorbed arsenic without the use of a radiolabel. Urinary excretion of arsenic above background levels can be measured following application of soluble arsenic, and absorption rates (0.6–4.4% absorption) are consistent with prior research using the more sensitive, radiolabeled technique. Additionally, the results show that arsenic is poorly absorbed from CCA-treated wood residues (i.e., does not result in urinary arsenic excretion above background levels). [ABSTRACT FROM AUTHOR]

Published
2004
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22. Predicting oral relative bioavailability of arsenic in soil from in vitro bioaccessibility

Author

Karen D. Bradham, Clay Nelson, Gary Diamond, David J. Thomas, Yvette W. Lowney, Albert L. Juhasz, Julie M Klotzbach, William J. Brattin, Michele Burgess, Cheryl A Hawkins, Susan Griffin, Kirk G. Scheckel, Diamond, Gary L, Bradham, Karen D, Brattin, William J, Burgess, Michele, Griffin, Susan, Hawkins, Cheryl, Juhasz, Albert L, Klotzbach, Julie M, Nelson, Clay, Lowney, Yvette W, Scheckel, Kirk G, and Thomas, David J

Subjects
Soil test, cadmium, Health, Toxicology and Mutagenesis, contaminated soils, Biological Availability, 010501 environmental sciences, Toxicology, 01 natural sciences, Models, Biological, Arsenic, Soil pH, Linear regression, errors, Soil Pollutants, Public, Environmental & Occupational Health, 0105 earth and related environmental sciences, validation, lead, Pesticide residue, Chemistry, swine, Soil classification, 04 agricultural and veterinary sciences, assay, Soil contamination, Bioavailability, Environmental chemistry, Soil water, 040103 agronomy & agriculture, Linear Models, 0401 agriculture, forestry, and fisheries, regression, Biological Assay, Environmental Sciences
Abstract

Several investigations have been conducted to develop in vitro bioaccessibility (IVBA) assays that reliably predict in vivo oral relative bioavailability (RBA) of arsenic (As). This study describes a meta-regression model relating soil As RBA and IVBA that is based upon data combined from previous investigations that examined the relationship between As IVBA and RBA when IVBA was determined using an extraction of soil in 0.4 M glycine at pH 1.5. Data used to develop the model included paired IVBA and RBA estimates for 83 soils from various types of sites such as mining, smelting, and pesticide or herbicide application. The following linear regression model accounted for 87% of the observed variance in RBA (R2 = .87): RBA(%) = 0.79 × IVBA(%) + 3.0. This regression model is more robust than previously reported models because it includes a larger number of soil samples, and also accounts for variability in RBA and IVBA measurements made on samples collected from sites contaminated with different As sources and conducted in different labs that have utilized different experimental models for estimating RBA.

Published
2016
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