874 results on '"Lozano, Guillermina"'
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2. The histone chaperone function of Daxx is dispensable for embryonic development
3. Is loss of p53 a driver of ductal carcinoma in situ progression?
4. Pancreatic epithelial IL-17/IL-17RA signaling drives B7-H4 expression to promote tumorigenesis
5. Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss
6. Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer
7. p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo
8. Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress
9. Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer.
10. Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
11. Inhibition of ULK1/2 and KRASG12Ccontrols tumor growth in preclinical models of lung cancer
12. Abstract A064: Identifying cooperating genetic events contributing to disease progression in mutant p53-driven breast cancer
13. p53R245W Mutation Fuels Cancer Initiation and Metastases in NASH-driven Liver Tumorigenesis
14. Supplementary Figure 2 from p53R245W Mutation Fuels Cancer Initiation and Metastases in NASH-driven Liver Tumorigenesis
15. Supplementary Figure 4 from p53R245W Mutation Fuels Cancer Initiation and Metastases in NASH-driven Liver Tumorigenesis
16. Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity
17. Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo
18. Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer
19. Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells
20. Abstract PO-086: Generation of HPV-negative tobacco-associated oral cancer models using p53 and Cdkn2a mutant mice
21. Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration
22. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells
23. Triple-negative breast tumors are dependent on mutant p53 for growth and survival
24. Synthetic Small Inhibiting RNAs: Efficient Tools to Inactivate Oncogenic Mutations and Restore p53 Pathways
25. Conflict management in wild chacma baboons (Papio cynocephalus ursinus)
26. High Metastatic Potential in Mice Inheriting a Targeted p53 Missense Mutation
27. Functional Activation of p53 via Phosphorylation Following DNA Damage by UV but not γ Radiation
28. Differential Activation of p53 Targets in Cells Treated with Ultraviolet Radiation That Undergo Both Apoptosis and Growth Arrest
29. Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
30. Data from Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program
31. Supplementary Tables S1-S9 and Figures S1-S9 from Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program
32. Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program
33. Figure S3 from Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
34. Data from DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
35. Data from p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis
36. Supplementary Materials and Methods from Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
37. Table S2 from p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis
38. Data from Daxx Functions Are p53-Independent In Vivo
39. Video 4 from DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
40. Figure S1 from p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis
41. Data from Therapeutic Efficacy of p53 Restoration in Mdm2-Overexpressing Tumors
42. Supplementary Materials from DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
43. Supplementary Figures 1 - 6, Table 1 from Therapeutic Efficacy of p53 Restoration in Mdm2-Overexpressing Tumors
44. Mutant p53-associated genes from Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
45. Supplementary Figure 1 from Daxx Functions Are p53-Independent In Vivo
46. Data from Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
47. Video 3 from DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
48. Supplementary Table S2 from The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model
49. Supplementary Figure S1 from The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model
50. Data from Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination
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