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214 results on '"Lu, Jianing"'

13. A virtual instrument to standardise the calibration of atomic force microscope cantilevers

Author

Sader, John E., Borgani, Riccardo, Gibson, Christopher T., Haviland, David B., Higgins, Michael J., Kilpatrick, Jason I., Lu, Jianing, Mulvaney, Paul, Shearer, Cameron J., Slattery, Ashley D., Thorén, Per-Anders, Tran, Jim, Zhang, Heyou, Zhang, Hongrui, and Zheng, Tian

Subjects
Physics - Instrumentation and Detectors, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Atomic force microscope (AFM) users often calibrate the spring constants of cantilevers using functionality built into individual instruments. This is performed without reference to a global standard, which hinders robust comparison of force measurements reported by different laboratories. In this article, we describe a virtual instrument (an internet-based initiative) whereby users from all laboratories can instantly and quantitatively compare their calibration measurements to those of others - standardising AFM force measurements - and simultaneously enabling non-invasive calibration of AFM cantilevers of any geometry. This global calibration initiative requires no additional instrumentation or data processing on the part of the user. It utilises a single website where users upload currently available data. A proof-of-principle demonstration of this initiative is presented using measured data from five independent laboratories across three countries, which also allows for an assessment of current calibration., Comment: 34 pages, 14 figures

Published
2016
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14. Scanning nano-spin ensemble microscope for nanoscale magnetic and thermal imaging

Author

Tetienne, Jean-Philippe, Lombard, Alain, Simpson, David A., Ritchie, Cameron, Lu, Jianing, Mulvaney, Paul, and Hollenberg, Lloyd C. L.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Quantum sensors based on solid-state spins provide tremendous opportunities in a wide range of fields from basic physics and chemistry to biomedical imaging. However, integrating them into a scanning probe microscope to enable practical, nanoscale quantum imaging is a highly challenging task. Recently, the use of single spins in diamond in conjunction with atomic force microscopy techniques has allowed significant progress towards this goal, but generalisation of this approach has so far been impeded by long acquisition times or by the absence of simultaneous topographic information. Here we report on a scanning quantum probe microscope which solves both issues, by employing a nano-spin ensemble hosted in a nanodiamond. This approach provides up to an order of magnitude gain in acquisition time, whilst preserving sub-100 nm spatial resolution both for the quantum sensor and topographic images. We demonstrate two applications of this microscope. We first image nanoscale clusters of maghemite particles through both spin resonance spectroscopy and spin relaxometry, under ambient conditions. Our images reveal fast magnetic field fluctuations in addition to a static component, indicating the presence of both superparamagnetic and ferromagnetic particles. We next demonstrate a new imaging modality where the nano-spin ensemble is used as a thermometer. We use this technique to map the photo-induced heating generated by laser irradiation of a single gold nanoparticle in a fluid environment. This work paves the way towards new applications of quantum probe microscopy such as thermal/magnetic imaging of operating microelectronic devices and magnetic detection of ion channels in cell membranes., Comment: 22 pages including Supporting Information. Changes to v1: affiliations and funding information updated, plus minor revisions to the main text

Published
2015
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27. Improving the accuracy of QoT estimation with insertion loss distribution evaluation for C + L band transmission systems

Author

Zhou, Jing, Lu, Jianing, and Yu, Changyuan

Abstract

The accuracy of quality of transmission (QoT) estimation is crucial for software-defined optical networks (SDONs), where network planning and system management of the centralized controller depend on reliable performance evaluation. The insertion loss (IL) commonly exists along the light path between the transmitter side (Tx) and the receiver side (Rx) in fiber optical transmission systems, and the IL values vary for each connector and pigtail. In the case of C + L band transmission systems that are about to be deployed on a large scale, in the presence of severe stimulated Raman scattering (SRS), IL further influences the launch power profile (LPP) as well as the noise spectrum, and the process in the QoT estimation will be disturbed without available IL values. Therefore, there is a great need for an accurate calculation method of IL distribution. In this paper, we propose a method to estimate IL distribution in fiber optical transmission links to improve the accuracy of QoT estimation based on the SRS effect. The results demonstrate that, compared with other common methods, our proposed method greatly improves the accuracy of QoT estimation for C + L band transmission systems with accurate IL distribution evaluation. The high accuracy, robustness, and ability to adapt dynamic conditions make our proposed method a promising QoT estimation scheme in practical C + L band fiber optical communication systems.

Published
2024
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28. Experiment Studies of a DC Inductive Superconducting Fault Current Limiter With Energy Dissipation Capability

Author

Wang, Changqi, Hong, Wei, Lu, Jianing, Li, Bin, Xin, Ying, Li, Wenxin, Yang, Tianhui, and Zhang, Yumin

Abstract

The fast dc fault current-limiting and the fast fault isolation are both necessary technologies in dc power system. In this research, a self-adaptive dc inductive superconducting fault current limiter (SFCL) with energy dissipation capability was proposed, which can restrict dc fault current rising-rate and amplitude at the initial stage of dc fault. At the same time, it can also accelerate the fault isolation speed of dc circuit breaker. The structure and working principle of the proposed SFCL was deeply discussed firstly, the mathematical model at different operation stages was calculated. Then, the dc short-circuit tests were carried out on the experiment platform which consist the SFCL prototype and a dc circuit breaker connected to it. Finally, according to the experiment results, the current-limiting performances of SFCL were detailedly analyzed, including the limitation rate, the fault current cleaning speed, the energy absorption, etc.

Published
2024
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30. Evaluation of depression in a mouse model of smog-induced chronic obstructive pulmonary disease.

Author

WANG Siyi, LU Jianing, and HUANG Qinghui

Subjects
*CHRONIC obstructive pulmonary disease, *LABORATORY mice, *ANIMAL disease models, *TOBACCO smoke, *PULMONARY function tests
Abstract

Objective To explore whether depression can occur in COPD mouse model induced by chronic exposure to tobacco smoke alone. Methods SPF grade mice were divided into control group (CLT group) and smoke exposure group (CS group). Mice in CS group were exposed to tobacco smoke for 24 weeks. Open field test and tail suspension test were performed 24 hours after the last smoking, and lung function test was performed after the test. The levels of IL-6 and KC in BALF supernatant were detected by ELISA, as well as the serum levels of 5-HT. H&E staining and Nissl staining were used to observe the pathological changes of lung and brain tissues of mice. Results Compared with CTL group, the body weight of mice in CS group grew slowly (P < 0.001), FRC and FVC were significantly increased (P < 0.001), and FEV20/FVC and FEV50/FVC were significantly decreased (P < 0.05). The expression levels of proinflammatory cytokines IL-6 and KC in BALF were increased (P < 0.01), and the content level of 5-HT in serum was significantly decreased (P < 0.001). The total movement distance, the number of times into the central area and the retention time in the central area of the CS group were significantly decreased in the open field test (P < 0.05), and the immobility time of the CS group was increased in the tail suspension test (P < 0.05 ). H&E staining showed that the mean alveolar intercept of lung tissue in the CS group was significantly increased (P < 0.001), and Nissl staining showed that the number of damaged neurons in the cortex (P < 0.001) and hippocampus (P < 0.01) in the CS group was significantly increased. Conclusion Chronic exposure to tobacco smoke alone induced COPD mouse models with depression. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Identification of an Independent Immune-Genes Prognostic Index for Breast Cancer

Author

Deng Rong, Yu yun, Lin chen, Dong Yuxiang, Pan Yitong, Zhang Yuhan, Wang Junyi, Chen chen, and Lu Jianing

Abstract

Objective: There are increasing evidences that the immune micro-environment of breast cancer (BC) seriously affects the clinical outcome. This study aims to explore the role of tumor immune genes in the prognosis of BC patients.Methods: We obtained the list of 2498 immune genes from ImmPort database. In addition, we obtained gene expression data and clinical characteristics data of BC patients from the TCGA database. The prognostic correlation of the differential genes was analyzed through Survival package. Cox regression analysis was performed to analyze the prognostic effect of immune genes. According to the regression coefficients of prognostic immune genes in regression analysis, an immune risk scores model was established. Gene set enrichment analysis (GSEA) was performed to probe the biological correlation of immune gene scores. P< 0.05 was considered to be statistically significant. Results: In total, 556 immune genes were differentially expressed in normal tissues and BC tissues (pConclusion:In a word, our study provides a new perspective for the expression of immune genes in BC. In addition, the immune risk scores have considerable advantages in predicting the survival of BC, which ares associated with a variety of oncogenic pathways.

Published
2020

47. Comparison of blur and magnification effects on stereopsis : overall and meridional, monocularly- and binocularly-induced

Author

Atchison, David A., Schmid, Katrina L., Haley, Emma C., Liggett, Elisabeth M., Lee, Sally J., Lu, Jianing, Moon, Ho Jung, Baldwin, Alex S., Hess, Robert F., Atchison, David A., Schmid, Katrina L., Haley, Emma C., Liggett, Elisabeth M., Lee, Sally J., Lu, Jianing, Moon, Ho Jung, Baldwin, Alex S., and Hess, Robert F.

Abstract

Purpose: To determine whether monocularly- and binocularly-induced spherical and meridional blur and aniseikonia had similar effects on stereopsis thresholds. Methods: Twelve participants with normal binocular vision viewed McGill modified random dot stereograms to determine stereoacuities in a four-alternative forced-choice procedure. Astigmatism was induced by placing trial lenses in front of the eyes. Twenty-three conditions were used, consisting of zero (no lens), +1 D and +2 D spheres and cylinders at axes 180, 45 and 90 in front of the right eye, and the following binocular combinations of both lens powers: R × 180/L × 180, R × 45/L × 45, R × 90/L × 90, R sphere/L sphere, R × 180/L × 90, R × 45/L × 135, R × 90/L × 180. Aniseikonia was induced by placing magnifying lenses in front of the eyes. Twenty-three conditions were used, consisting of zero, 6% and 12% overall magnification and both magnifications at axes 180, 45 and 90 in front of the right eye only, and the following binocular combinations using 3% and 6% lenses: R × 90/L × 90, R × 45/L × 45, R × 180/L × 180, R overall/L overall, R × 90/L × 180, R × 45/L × 135, and R × 180/L × 90. Results: Stereopsis losses for binocular blur effects with parallel axes (non-anisometropic) were the same as for monocular blur effects of the same axes, and these were strongly dependent on axis (spherical blur and ×90 had the greatest effects). Binocular blur effects with orthogonal axes had greater effects than with parallel axes, with the axis combination of the former having no effect (e.g. R × 90/L × 180 was similar to R × 45/L × 135). For induced aniseikonia, splitting the magnifications between the eyes improved stereopsis slightly, and the effects were not dependent on axis. Conclusion: Binocular blur affects stereopsis similarly to monocular meridional blur if axes in the two eyes are parallel, whereas the effect is greater if the axes are orthogonal. In meridional aniseikonia, splitting magnification between the

Published
2020

48. Effects of simulated anisometropia and aniseikonia on stereopsis

Author

Atchison, David A., Lee, Jeongmin, Lu, Jianing, Webber, Ann L., Hess, Robert F., Baldwin, Alex S., Schmid, Katrina L., Atchison, David A., Lee, Jeongmin, Lu, Jianing, Webber, Ann L., Hess, Robert F., Baldwin, Alex S., and Schmid, Katrina L.

Abstract

Purpose: Stereopsis depends on horizontally disparate retinal images but otherwise concordance between eyes. Here we investigate the effect of spherical and meridional simulated anisometropia and aniseikonia on stereopsis thresholds. The aims were to determine effects of meridian, magnitude and the relative effects of the two conditions. Methods: Ten participants with normal binocular vision viewed McGill modified random dot stereograms through synchronised shutter glasses. Stereoacuities were determined using a four-alternative forced-choice procedure. To induce anisometropia, trial lenses of varying power and axes were placed in front of right eyes. Seventeen combinations were used: zero (no lens) and both positive and negative, 1 and 2 D powers, at 45, 90 and 180 axes; spherical lenses were also tested. To induce aniseikonia 17 magnification power and axis combinations were used. This included zero (no lens), and 3%, 6%, 9% and 12% at axes 45, 90 and 180; overall magnifications were also tested. Results: For induced anisometropia, stereopsis loss increased as cylindrical axis rotated from 180° to 90°, at which the loss was similar to that for spherical blur. For example, for 2 D meridional anisometropia threshold increased from 1.53 log sec arc (i.e. 34 sec arc) for x 180 to 1.89 log sec arc (78 sec arc) for x 90. Anisometropia induced with either positive or negative lenses had similar detrimental effects on stereopsis. Unlike anisometropia, the stereopsis loss with induced meridional aniseikonia was not affected by axis and was about 64% of that for overall aniseikonia of the same amount. Approximately, each 1 D of induced anisometropia had the same effect on threshold as did each 6% of induced aniseikonia. Conclusion: The axes of meridional anisometropia but not aniseikonia affected stereopsis. This suggests differences in the way that monocular blur (anisometropia) and interocular shape differ

Published
2020

49. Performance comparisons between machine learning and analytical models for quality of transmission estimation in wavelength-division-multiplexed systems [Invited]

Author

Lu, Jianing, primary, Zhou, Gai, additional, Fan, Qirui, additional, Zeng, Dengke, additional, Guo, Changjian, additional, Lu, Linyue, additional, Li, Jianqiang, additional, Xie, Chongjin, additional, Lu, Chao, additional, Khan, Faisal Nadeem, additional, and Lau, Alan Pak Tao, additional

Published
2021
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