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22 results on '"Lu, Sha-Sha"'

7. Synthesis and Modification of a Lamellar Co3O4 Anode for Lithium-Ion Batteries

Author

LU Sha-Sha, Wang Xue-Jun, Xu Shengming, Huang Guoyong, and LI Lin-Yan

Subjects
Materials science, Scanning electron microscope, Oxide, Analytical chemistry, chemistry.chemical_element, Thermal treatment, Anode, Crystallinity, chemistry.chemical_compound, chemistry, Phase (matter), Lamellar structure, Lithium, Physical and Theoretical Chemistry
Abstract

For advanced performance lithium-ion batteries (LIBs) various novel electrode materials with high energy density have been extensively investigated. Cobaltosic oxide (Co3O4), commonly used as an anode in LIBs, has attracted much interest because of its high theoretical specific capacity (890 mAh∙g - 1 ), high tap density, and stable chemical properties. However, its practical use has been hindered because of its low electronic conductivity and poor rate capability. To address these problems, we investigated a liquid phase precipitation method followed by thermal treatment and obtained a unique lamellar Co3O4 powder. Its X-ray diffraction (XRD) diffraction peaks match the standard pattern for cubic phase Co3O4 with good crystallinity. We found that the Co3O4 powder consists of many irregular sheets (1.5-3.0 µm in diameter, 100-300 nm in thickness) with numerous poles by scanning electron microscopy (SEM).Additionally, the surface area was about 30.5 m 2

Published
2014

9. Impact of Chemotherapy Delay on Overall Survival for AML with I DH1/2 Mutations: A Study in Adult Chinese Patients

Author

Wang, Jing Han, primary, Guo, Qi, additional, Ma, Zhi Xin, additional, Ma, Qiu Ling, additional, Yu, Meng Xia, additional, Yin, Xiu Feng, additional, Lu, Sha Sha, additional, Xie, Qiong Hong, additional, Jiang, Yue Hong, additional, Shen, Dan, additional, Ma, li Ya, additional, Shi, Hui, additional, Yu, Wen Juan, additional, Lou, Ye Jiang, additional, Li, Ying, additional, Yang, Min, additional, Xu, Gai Xiang, additional, Mao, Li Ping, additional, Li, Jian Hu, additional, Wang, Fan Ping, additional, Wang, Dong Mei, additional, Wei, Ju Ying, additional, Tong, Hong Yan, additional, Huang, Jian, additional, and Jin, Jie, additional

Published
2015
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10. Impact of Chemotherapy Delay on Overall Survival for AML with IDH1/2 Mutations: A Study in Adult Chinese Patients

Author

Wang, Jing-Han, primary, Guo, Qi, additional, Ma, Zhi-Xin, additional, Ma, Qiu-Ling, additional, Yu, Meng-Xia, additional, Yin, Xiu-Feng, additional, Lu, Sha-Sha, additional, Xie, Hong-Qiong, additional, Jiang, Yue-Hong, additional, Shen, Dan, additional, Ma, Li-Ya, additional, Shi, Hui, additional, Yu, Wen-Juan, additional, Lou, Ye-Jiang, additional, Li, Ying, additional, Yang, Min, additional, Xu, Gai-Xiang, additional, Mao, Li-Ping, additional, Li, Jian-Hu, additional, Wang, Huan-Ping, additional, Wang, Dong-Mei, additional, Wei, Ju-Ying, additional, Tong, Hong-Yan, additional, Huang, Jian, additional, and Jin, Jie, additional

Published
2015
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11. HighIDH1expression is associated with a poor prognosis in cytogenetically normal acute myeloid leukemia

Author

Ma, Qiu-Ling, primary, Wang, Jing-Han, additional, Wang, Yun-Gui, additional, Hu, Chao, additional, Mu, Qi-Tian, additional, Yu, Meng-Xia, additional, Wang, Lei, additional, Wang, Dong-Mei, additional, Yang, Min, additional, Yin, Xiu-Feng, additional, Chen, Fei-Fei, additional, Lu, Sha-Sha, additional, Chen, Jian, additional, Zhu, Zhi-Juan, additional, Chen, Sai-Juan, additional, and Jin, Jie, additional

Published
2015
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12. High IDH1 Expression Is Associated with a Poor Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

Author

Ma, Qiu-Ling, primary, Wang, Jing-Han, additional, Wang, Yun-gui, additional, Hu, Chao, additional, Mu, Qi-Tian, additional, Yu, Meng-Xia, additional, Wang, Lei, additional, Wang, Dong-Mei, additional, Yang, Min, additional, Yin, Xiu-Feng, additional, Chen, Fei-Fei, additional, Lu, Sha-Sha, additional, Chen, Jian, additional, Zhu, Zhi-Juan, additional, Chen, Sai-Juan, additional, and Jin, Jie, additional

Published
2014
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18. Development of a Colloidal Gold-Based Immunochromatographic Assay for the Rapid Detection of Aflatoxin B1 in Food Samples

Author

Chen, Xue Qing, Lu, Sha Sha, Sun, Qing, Yang, Jing Chen, and Shi, Guo Qing

Abstract

A rapid and sensitive competitive immunochromatographic assay for aflatoxin B1 (AFB1) based on colloidal gold-antibody probe was developed. The limit of detection for AFB1 standard solution was 0.5ng/ml and for foodstuff sample was 10μg/Kg. Other aflatoxins including AFM1, AFB2, AFG1, and AFG2 have less cross-reactivity to the strip. The storge life of the strip was at least 12 monthes. The method was well agreement with the ELISA method by testing food samples. This method is suitable for rapid testing of AFB1 on site.

Published
2013
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19. Impact of Chemotherapy Delay on Overall Survival for AML with I DH1/2Mutations: A Study in Adult Chinese Patients

Author

Wang, Jing Han, Guo, Qi, Ma, Zhi Xin, Ma, Qiu Ling, Yu, Meng Xia, Yin, Xiu Feng, Lu, Sha Sha, Xie, Qiong Hong, Jiang, Yue Hong, Shen, Dan, Ma, li Ya, Shi, Hui, Yu, Wen Juan, Lou, Ye Jiang, Li, Ying, Yang, Min, Xu, Gai Xiang, Mao, Li Ping, Li, Jian Hu, Wang, Fan Ping, Wang, Dong Mei, Wei, Ju Ying, Tong, Hong Yan, Huang, Jian, and Jin, Jie

Abstract

The effect of time from diagnosis to treatment (TDT) on overall survival of patients with acute myeloid leukemia (AML) remain obscure. Furthermore, whether chemotherapy delay impacts overall survival (OS) of patients with a special molecular subtype has not been investigated. Here, we enrolled 364 cases of AML to assess the effect of TDT on OS by fractional polynomial regression in the context of clinical parameters and genes of FLT3ITD, NPM1, CEBPA, DNMT3a, and IDH1/2mutations. Results of the current study show IDH1/2mutations are associated with older age, M0 morphology, an intermediate cytogenetic risk group, and NPM1mutations. TDT associates with OS for AML patients in a nonlinear pattern with a J shape. Moreover, adverse effect of delayed treatment on OS was observed in patients with IDH1/2mutations, but not in those with IDH1/2wild type. Therefore, initiating chemotherapy as soon as possible after diagnosis might be a potential strategy to improve OS in AML patients with IDH1/2mutations.

Published
2015
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21. [The clinical manifestation and linkage analysis in one Chinese family with congenital fibrosis of extraocular muscles].

Author

Zhao C, Lu SS, Li ND, Chen WY, and Zhao KX

Subjects
Asian People genetics, Base Sequence, Blepharoptosis ethnology, Blepharoptosis pathology, China, Female, Fibrosis congenital, Fibrosis genetics, Genetic Linkage, Humans, Lod Score, Male, Microsatellite Repeats, Ophthalmoplegia ethnology, Ophthalmoplegia pathology, Pedigree, Phenotype, Sequence Analysis, DNA, Syndrome, Blepharoptosis genetics, Chromosomes, Human, Pair 12 genetics, Genetic Predisposition to Disease, Oculomotor Muscles pathology, Ophthalmoplegia genetics
Abstract

Objective: To describe the clinical phenotype in a Chinese family with congenital fibrosis of extraocular muscles and to identify the location of candidate gene of the disease in chromosome., Methods: The clinical feature of all affected members in this family were examined. A genome-wide linkage screening was conducted. Direct genomic sequencing was used to evaluate the candidate gene KIf21A., Results: Four affected members in the pedigree were born with classic phenotype of CFEOM. By linkage analysis the disease gene was mapped to chromosomal region 12p11.2-q12 defined by microsatellite markers D12S1648 and D12S1668. The maximum Lod Score was 2.12 (D12S1090). Direct sequence showed no mutation in all exons and exon-intron boundaries of the candidate gene KIF21A, a polymorphism substitution occurred in the exon 21., Conclusions: The disorder in this family should be referred as CFEOM1 which was inherited as an autosomal dominant trait. The candidate gene was linked to CFEOM1 locus on chromosome 12p11.2-q12, between marker D12S1648 and D12S1668. It's more likely that KIf21A is not the disease causing gene in this family.

Published
2005

22. [Novel splice-site mutation in the pre-mRNA splicing gene PRPF31 in a Chinese family with autosomal dominant retinitis pigmentosa].

Author

Lu SS, Zhao C, Cui Y, Li ND, Zhang XM, and Zhao KX

Subjects
Asian People genetics, Chromosomes, Human, Pair 19 genetics, Female, Frameshift Mutation, Genes, Dominant, Genetic Linkage, Humans, Male, Pedigree, Eye Proteins genetics, RNA Splice Sites genetics, Retinitis Pigmentosa genetics
Abstract

Objective: To identify mutations in a four-generation Chinese family with retinitis pigmentosa and to investigate its clinical phenotype., Methods: Ophthalmic and electrophysiological examinations of patients with RP were performed. A genome-wide scan and linkage analysis were conducted in this family. Direct genomic sequencing was used to evaluate the candidate gene. A restriction assay was used to confirm the mutation status in this family, and to exclude it as a polymorphism in a reference population., Results: The mutation gene was mapped close to RP11 in chromosomal region 19q13.4 by linkage analysis. A novel single heterozygous base substitution (G > C) was detected at the beginning of intron 8 in the PRPF31 gene whereby the consensus GT dinucleotide of the intron 8 splice donor site was changed to CT. The mutation was co-segregated completely with the disease phenotype, but was absent in the unaffected relatives and in 100 reference subjects, thus supporting its pathogenic nature in this family. The clinical findings of RP patients were consistent with a relatively severe and diffuse type of RP., Conclusion: A novel splice site mutation (IVS8 + 1G > C) in the PRPF31 gene caused retinitis pigmentosa in the four-generation Chinese RP family studied.

Published
2005

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