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15. Models in Wound Healing

Author

Miao, Ming Yuan, Xie, Ting, Lu, Shuliang, Mani, Raj, Mani, Raj, editor, Romanelli, Marco, editor, and Shukla, Vijay, editor

Published
2013
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25. Additional file 5 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 5: Supplemental Figure S5. Relationship of EAPCs in burns incidence, DALYs, and death with SDI, UHC, and GDP. A, correlation analysis of the EAPC of ASDR with GDP. EAPC, estimated annual percentage change; DALYs, disability-adjusted life years; SDI, sociodemographic index; UHC, universal health coverage; GDP, gross domestic product; ASDR, age-standardized death rate.

Published
2022
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26. Additional file 1 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 1: Supplemental Figure S1. Incidence of burns. A, the global changing trend in ASIR by sex from 1990 to 2019. B, a comparison of the number of new cases between 1990 and 2019 at global and different SDI levels. C, distribution of new cases among different age categories in 1990. D, distribution of incidence rate among different age categories in 2019. E, distribution of incidence rate among different age categories in 1990. F, a comparison of the number of new cases by sex globally and at different SDI levels in 2019. G, a comparison of the number of new cases by sex at global and different SDI levels in 1990. H, a comparison of the ASIR by sex at global and different SDI levels in 1990. I, the range of change in the number of new cases by sex in 2019 compared with 1990 in 45 GBD regions. J, the rangeability in ASIR by sex in 2019 compared with 1990 in 45 GBD regions. K, the map of ASIR in 2019 among 204 countries and territories. SDI, sociodemographic index; ASIR, age-standardized incidence rate; GBD, Global Burden of Disease.

Published
2022
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27. Additional file 2 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 2: Supplemental Figure S2. DALYs of burns. A, the global changing trend in the number of ASDAR by sex from 1990 to 2019. B, a comparison of the ASDAR between 1990 and 2019 at global and different SDI levels. C, distribution of DALYs rate among different age categories in 2019. D, distribution of DALYs rate among different age categories in 1990. E, the range of change in DALYs by sex in 2019 compared to 1990 in 45 GBD regions. F, the range of change in ASDAR by sex in 2019 compared to 1990 in 45 GBD regions. G, the top increased or decreased in DALYs by sex in 2019 compared with 1990 among 204 countries and territories. H, the top increased or decreased in ASDAR by sex in 2019 compared with 1990 among 204 countries and territories. I, distribution of DALYs among different age categories in 1990. J, the map of DALYs in 2019 among 204 countries and territories. K, the map of ASDAR in 2019 among 204 countries and territories. DALYs, disability-adjusted life years; SDI, sociodemographic index; ASDAR, age-standardized DALYs rate; GBD, Global Burden of Disease.

Published
2022
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28. Additional file 4 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 4: Supplemental Figure S4. Temporal Trends of burns. A, the EAPC of incidence in 45 GBD regions. B, the EAPC of deaths in 45 GBD regions. C, the map of deaths EAPC in 2019 among 204 countries and territories. D, the map of DALYs EAPC in 2019 among 204 countries and territories. EAPC, estimated annual percentage change; DALYs, disability-adjusted life years; GBD, Global Burden of Disease.

Published
2022
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29. Additional file 6 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 6: Table S3. GBD location hierarchy with levels (Table from:Diseases, G.B.D. and C. Injuries, Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet (London, England), 2020. 396(10258): p. 1204-1222. ).

Published
2022
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30. Additional file 3 of The epidemiological characteristic and trends of burns globally

Author

Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, and Lu, Shuliang

Abstract

Additional file 3: Supplemental Figure S3. Mortality of burns. A, the global changing trend of the ASDR by sex from 1990 to 2019. B, a comparison of ASDR between 1990 and 2019 at global and between different SDI levels. C, distribution of death rate among different age categories in 2019. D, distribution of the number of death cases among different age categories in 1990. E, a comparison of the number of death cases by sex at global and different SDI levels in 1990. F, a comparison of ASDR by sex at global and between different SDI levels in 2019. G, the range of change in the number of death cases by sex in 2019 compared with 1990 in 45 GBD regions. H, the range of change in ASDR by sex in 2019 compared with 1990 in 45 GBD regions. I, the top increased or decreased in the number of death cases by sex in 2019 compared with 1990 among 204 countries and territories. J, the top increased or decreased in ASDR by sex in 2019 compared with 1990 among 204 countries and territories. K, the map of death cases number in 2019 among 204 countries and territories. SDI, sociodemographic index; ASDR, age-standardized death rate; GBD, Global Burden of Disease.

Published
2022
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35. Fractal analysis of rat dermal tissue in the different injury states

Author

Xu, Haisong, primary, Zhang, Jingde, additional, Jiang, Yuzhi, additional, Lu, Shuliang, additional, Niu, Yiwen, additional, Dong, Jiaoyun, additional, Jin, Shuwen, additional, Song, Fei, additional, Cao, Xiaozan, additional, Qing, Chun, additional, Tian, Ming, additional, and Liu, Yingkai, additional

Published
2021
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36. The application value of computed tomography and magnetic resonance imaging sinography/fistulography in evaluating chronic wounds: a prospective study

Author

Wang, Hanqi, primary, Yakupu, Aobuliaximu, additional, Ma, Xian, additional, Tao, Guilu, additional, Zhang, Di, additional, Li, Zhihui, additional, Pan, Yalin, additional, Chen, Tongtong, additional, Chen, Liuping, additional, Lv, Haiying, additional, Yan, Fuhua, additional, Lu, Shuliang, additional, and Lu, Yong, additional

Published
2021
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38. CO2 Laser Debridement and Negative Pressure Wound Therapy With Endoscopic Support for Treatment of Sinus Wound at the Ischial Tuberosity: Case Report.

Author

Tang, JiaJun, Tao, Guilu, Liu, Yingkai, Ma, Xian, Aobuliaximu, Yakupu, and Lu, Shuliang

Abstract

The sinus tract of the ischial tuberosity is often caused by pressure injury. It has the characteristics of difficult treatment and high cost, which increases the anxiety of patients and reduces the quality of life of patients. This case report is to describe an effective method to treat sinus wound at the ischial tuberosity. A 53-year-old male suffered pressure ulcer with sinus wound at the left ischial tuberosity due to inadequate walking and sedentary activity. On the basis of pressure relief and immobilization, the patient was treated with CO2 laser debridement and negative pressure wound therapy under endoscope support 3 times, the deep of the sinus wound was completely closed, and then the residual superficial wound was treated by skin grafting. Follow-up of 1 year after healing showed no recurrence of wound. [ABSTRACT FROM AUTHOR]

Published
2022
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39. Application of Compound Polymyxin B Ointment in the Treatment of Chronic Refractory Wounds.

Author

Tang, Jiajun, Guan, Haonan, Dong, Wei, Liu, Yingkai, Dong, Jiaoyun, Huang, Lifang, Zhou, Jingqi, and Lu, Shuliang

Abstract

The purpose of this study was to investigate the clinical efficacy of compound polymyxin B ointment for treating chronic refractory wounds. A retrospective analysis was performed on 111 patients who underwent chronic refractory wound treatment. Patients were divided into 2 groups, with 45 patients included in the experimental group (compound polymyxin B group) and 66 patients included in the control group (silver sulfadiazine group). After thorough debridement in both groups, either compound polymyxin B ointment or silver sulfadiazine cream was evenly applied to the patient's wound and covered with sterile gauze. In both groups, dressing changes were dependent on the wound's condition and secretions. Using the Bates-Jensen Wound Assessment Tool (BWAT), patients in both groups were scored, after which wound healing, infection, and healing time were compared. There was no significant difference in BWAT scores between the 2 groups on the 7th or 14th day; however, on the 21st day, the BWAT score in the experimental group was significantly lower than that of the control group. The difference was statistically significant (P <.05). There was no significant difference in the BWAT-I scores between the 2 groups on the seventh day. The healing time in the experimental group was significantly shorter than that of the control group, and the difference was statistically significant (P <.05). For the treatment of chronic refractory wounds, thorough debridement followed by compound polymyxin B ointment topical application can reduce and control wound infection effectively and accelerate the process of wound repair. [ABSTRACT FROM AUTHOR]

Published
2022
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43. Fractal analysis of rat dermal tissue in the different injury states.

Author

Xu, Haisong, Zhang, Jingde, Jiang, Yuzhi, Lu, Shuliang, Niu, Yiwen, Dong, Jiaoyun, Jin, Shuwen, Song, Fei, Cao, Xiaozan, Qing, Chun, Tian, Ming, and Liu, Yingkai

Subjects
COLLAGEN, WOUND healing, PENTOBARBITAL, STATISTICAL significance, BURNS & scalds, ANIMAL experimentation, ONE-way analysis of variance, QUANTITATIVE research, INTRAPERITONEAL injections, DIABETES, MATHEMATICS, SKIN physiology, RATS, T-test (Statistics), DERMIS, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis software
Abstract

Scar formation and chronic ulcers can develop following a skin injury. They are the result of the over‐ or underproduction of collagen. It is very important to evaluate the quality and quantity of the collagen that is produced during wound healing, especially with respect to its structure, as these factors are very important to a complicated outcome. However, there is no standard way to quantitatively analyse dermal collagen. As prior work characterised some potentially fractal properties of collagen, it was hypothesised that collagen structure could be evaluated with fractal dimension analysis. Small‐angle X‐ray scattering technology (SAXS) was used to evaluate the dermis of rats exposed to graft harvest, burn, and diabetic pathologic states. It was found that almost all collagen structures could be quantitatively measured with fractal dimension analysis. Further, there were significant differences in the three‐dimensional (3‐D) structure of normal collagen versus that measured in pathologic tissues. There was a significant difference in the 3‐D structure of collagen at different stages of healing. The findings of this work suggest that fractal analysis is a good tool for wound healing analysis, and that quantitative collagen analysis is very useful for assessing the structure of dermal collagen. [ABSTRACT FROM AUTHOR]

Published
2022
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