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Your search keyword '"Luca R. Pasqualotto"' showing total 3 results
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3 results on '"Luca R. Pasqualotto"'

1. Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation

Author

Cristina T. Okamoto, Carlos F. Oldenburg Neto, Sandra Mara Witkowski, Ana Paula Percicote, Luca R. Pasqualotto, Gabriela Troiano, Tammy Almeida, Cleber M. Souza, and Lúcia de Noronha

Subjects
displasia broncopulmonar, imuno-histoquímica, nascimento prematuro, oxigenoterapia, neonatologia, Pathology, RB1-214
Abstract

ABSTRACT INTRODUCTION: Chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia (BPD), is a major cause of morbidity in premature newborn and were submitted to oxygen therapy. OBJECTIVE: Immunohistochemical identification of inflammatory molecules in the lung tissue of premature neonates that died with CLD. METHODS: Immunohistochemical analysis of 51 samples of premature newborn lungs – grouped in: without CLD,"classic" CLD and"new" CLD. RESULTS: Neutrophil influx and the number of CD4+ and CD45RO+ cells were higher in the"classic" CLD group (p < 0.001). CONCLUSION: Our findings suggest that the inflammatory response is mediated by neutrophils and CD45RO+ and CD4+ T lymphocytes in the"classic" CLD.

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2. Fatores modificáveis da degeneração macular relacionada à idade

Author

Dalton Bertolim Précoma, Rogil José de Almeida Torres, Guilherme Winter, Cristina Muccioli, Luca R. Pasqualotto, Greyce Kelly de Souza, Andréa Luchini, and Mauricio Maia

Subjects
Ophthalmology, medicine.medical_specialty, Pediatrics, business.industry, Intervention (counseling), medicine, General Medicine, Macular degeneration, business, medicine.disease, Surgery
Abstract

The authors present the main modifiable risk factors that may trigger and/or worsen age-related macular degeneration. Mechanisms of action related to these factors as well as preventive measures and intervention effectiveness are discussed.

Published
2009

3. Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation

Author

Cristina T. Okamoto, Luca R. Pasqualotto, Tammy Almeida, Cleber Machado de Souza, Carlos F. Oldenburg Neto, Gabriela Troiano, Sandra Mara Witkowski, Lucia de Noronha, and Ana Paula Percicote

Subjects
Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_treatment, nascimento prematuro, Clinical Biochemistry, neonatologia, oxygen therapy, displasia broncopulmonar, neonatology, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, imuno-histoquímica, 030225 pediatrics, Oxygen therapy, bronchopulmonary dysplasia, medicine, lcsh:Pathology, 030212 general & internal medicine, Neonatology, Mechanical ventilation, Cell adhesion molecule, business.industry, premature birth, respiratory system, medicine.disease, respiratory tract diseases, Medical Laboratory Technology, Bronchopulmonary dysplasia, Lung disease, Premature birth, immunochemistry, Immunohistochemistry, business, oxigenoterapia, lcsh:RB1-214
Abstract

INTRODUCTION: Chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia (BPD), is a major cause of morbidity in premature newborn and were submitted to oxygen therapy. OBJECTIVE: Immunohistochemical identification of inflammatory molecules in the lung tissue of premature neonates that died with CLD. METHODS: Immunohistochemical analysis of 51 samples of premature newborn lungs – grouped in: without CLD,"classic" CLD and"new" CLD. RESULTS: Neutrophil influx and the number of CD4+ and CD45RO+ cells were higher in the"classic" CLD group (p < 0.001). CONCLUSION: Our findings suggest that the inflammatory response is mediated by neutrophils and CD45RO+ and CD4+ T lymphocytes in the"classic" CLD.

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