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1. NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells

Author

Geles, Kenneth G., Gao, Yijie, Giannakou, Andreas, Sridharan, Latha, Yamin, Ting-Ting, Zhang, Jing, Karim, Riyez, Bard, Joel, Piche-Nicholas, Nicole, Charati, Manoj, Maderna, Andreas, Lucas, Judy, Golas, Jonathon, Guffroy, Magali, Pirie-Shepherd, Steven, Roy, Marc, Qian, Jessie, Franks, Tania, Zhong, Wenyan, O’Donnell, Christopher J., Tchistiakova, Lioudmila, Gerber, Hans-Peter, and Sapra, Puja

Published
2021
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2. Table S5 from PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers

Author

Graziani, Edmund I., primary, Sung, Matthew, primary, Ma, Dangshe, primary, Narayanan, Bitha, primary, Marquette, Kimberly, primary, Puthenveetil, Sujiet, primary, Tumey, L. Nathan, primary, Bikker, Jack, primary, Casavant, Jeffrey, primary, Bennett, Eric M., primary, Charati, Manoj B., primary, Golas, Jonathon, primary, Hosselet, Christine, primary, Rohde, Cynthia M., primary, Hu, George, primary, Guffroy, Magali, primary, Falahatpisheh, Hadi, primary, Finkelstein, Martin, primary, Clark, Tracey, primary, Barletta, Frank, primary, Tchistiakova, Lioudmila, primary, Lucas, Judy, primary, Rosfjord, Edward, primary, Loganzo, Frank, primary, O'Donnell, Christopher J., primary, Gerber, Hans-Peter, primary, and Sapra, Puja, primary

Published
2023
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3. Supplementary Methods, Figures S1-S10, and Table S1 from Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)

Author

Sung, Matthew, primary, Tan, Xingzhi, primary, Lu, Bingwen, primary, Golas, Jonathan, primary, Hosselet, Christine, primary, Wang, Fang, primary, Tylaska, Laurie, primary, King, Lindsay, primary, Zhou, Dahui, primary, Dushin, Russell, primary, Myers, Jeremy S., primary, Rosfjord, Edward, primary, Lucas, Judy, primary, Gerber, Hans-Peter, primary, and Loganzo, Frank, primary

Published
2023
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4. Data from Anti-Extra Domain B Splice Variant of Fibronectin Antibody–Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

Author

Hooper, Andrea T., primary, Marquette, Kimberly, primary, Chang, Chao-Pei Betty, primary, Golas, Jonathon, primary, Jain, Sadhana, primary, Lam, My-Hanh, primary, Guffroy, Magali, primary, Leal, Mauricio, primary, Falahatpisheh, Hadi, primary, Mathur, Divya, primary, Chen, Ting, primary, Kelleher, Kerry, primary, Khandke, Kiran, primary, Muszynska, Elwira, primary, Loganzo, Frank, primary, Rosfjord, Edward, primary, Lucas, Judy, primary, Kan, Zhengyan, primary, Subramanyam, Chakrapani, primary, O'Donnell, Christopher, primary, Neri, Dario, primary, Gerber, Hans-Peter, primary, May, Chad, primary, and Sapra, Puja, primary

Published
2023
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5. Supplementary Methods, Table S1 S2, and Figure Legends from Tumor Cells Chronically Treated with a Trastuzumab–Maytansinoid Antibody–Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments

Author

Loganzo, Frank, primary, Tan, Xingzhi, primary, Sung, Matthew, primary, Jin, Guixian, primary, Myers, Jeremy S., primary, Melamud, Eugene, primary, Wang, Fang, primary, Diesl, Veronica, primary, Follettie, Maximillian T., primary, Musto, Sylvia, primary, Lam, My-Hanh, primary, Hu, William, primary, Charati, Manoj B., primary, Khandke, Kiran, primary, Kim, Kenny Sung Kyoo, primary, Cinque, Mike, primary, Lucas, Judy, primary, Graziani, Edmund, primary, Maderna, Andreas, primary, O'Donnell, Christopher J., primary, Arndt, Kim T., primary, and Gerber, Hans-Peter, primary

Published
2023
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6. Supplementary Figures S1 to S11 from Tumor Cells Chronically Treated with a Trastuzumab–Maytansinoid Antibody–Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments

Author

Loganzo, Frank, primary, Tan, Xingzhi, primary, Sung, Matthew, primary, Jin, Guixian, primary, Myers, Jeremy S., primary, Melamud, Eugene, primary, Wang, Fang, primary, Diesl, Veronica, primary, Follettie, Maximillian T., primary, Musto, Sylvia, primary, Lam, My-Hanh, primary, Hu, William, primary, Charati, Manoj B., primary, Khandke, Kiran, primary, Kim, Kenny Sung Kyoo, primary, Cinque, Mike, primary, Lucas, Judy, primary, Graziani, Edmund, primary, Maderna, Andreas, primary, O'Donnell, Christopher J., primary, Arndt, Kim T., primary, and Gerber, Hans-Peter, primary

Published
2023
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7. Data from Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)

Author

Sung, Matthew, primary, Tan, Xingzhi, primary, Lu, Bingwen, primary, Golas, Jonathan, primary, Hosselet, Christine, primary, Wang, Fang, primary, Tylaska, Laurie, primary, King, Lindsay, primary, Zhou, Dahui, primary, Dushin, Russell, primary, Myers, Jeremy S., primary, Rosfjord, Edward, primary, Lucas, Judy, primary, Gerber, Hans-Peter, primary, and Loganzo, Frank, primary

Published
2023
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8. Figure S1 from PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers

Author

Graziani, Edmund I., primary, Sung, Matthew, primary, Ma, Dangshe, primary, Narayanan, Bitha, primary, Marquette, Kimberly, primary, Puthenveetil, Sujiet, primary, Tumey, L. Nathan, primary, Bikker, Jack, primary, Casavant, Jeffrey, primary, Bennett, Eric M., primary, Charati, Manoj B., primary, Golas, Jonathon, primary, Hosselet, Christine, primary, Rohde, Cynthia M., primary, Hu, George, primary, Guffroy, Magali, primary, Falahatpisheh, Hadi, primary, Finkelstein, Martin, primary, Clark, Tracey, primary, Barletta, Frank, primary, Tchistiakova, Lioudmila, primary, Lucas, Judy, primary, Rosfjord, Edward, primary, Loganzo, Frank, primary, O'Donnell, Christopher J., primary, Gerber, Hans-Peter, primary, and Sapra, Puja, primary

Published
2023
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9. Supplementary Methods and Materials, Supplementary Figures 1-8, Supplementary Figure Legends, Supplementary Tables 1-3 from Long-term Tumor Regression Induced by an Antibody–Drug Conjugate That Targets 5T4, an Oncofetal Antigen Expressed on Tumor-Initiating Cells

Author

Sapra, Puja, primary, Damelin, Marc, primary, DiJoseph, John, primary, Marquette, Kimberly, primary, Geles, Kenneth G., primary, Golas, Jonathon, primary, Dougher, Maureen, primary, Narayanan, Bitha, primary, Giannakou, Andreas, primary, Khandke, Kiran, primary, Dushin, Russell, primary, Ernstoff, Elana, primary, Lucas, Judy, primary, Leal, Mauricio, primary, Hu, George, primary, O'Donnell, Christopher J., primary, Tchistiakova, Lioudmila, primary, Abraham, Robert T., primary, and Gerber, Hans-Peter, primary

Published
2023
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10. Data from Long-term Tumor Regression Induced by an Antibody–Drug Conjugate That Targets 5T4, an Oncofetal Antigen Expressed on Tumor-Initiating Cells

Author

Sapra, Puja, primary, Damelin, Marc, primary, DiJoseph, John, primary, Marquette, Kimberly, primary, Geles, Kenneth G., primary, Golas, Jonathon, primary, Dougher, Maureen, primary, Narayanan, Bitha, primary, Giannakou, Andreas, primary, Khandke, Kiran, primary, Dushin, Russell, primary, Ernstoff, Elana, primary, Lucas, Judy, primary, Leal, Mauricio, primary, Hu, George, primary, O'Donnell, Christopher J., primary, Tchistiakova, Lioudmila, primary, Abraham, Robert T., primary, and Gerber, Hans-Peter, primary

Published
2023
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11. Supplementary Data from Anti-Extra Domain B Splice Variant of Fibronectin Antibody–Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

Author

Hooper, Andrea T., primary, Marquette, Kimberly, primary, Chang, Chao-Pei Betty, primary, Golas, Jonathon, primary, Jain, Sadhana, primary, Lam, My-Hanh, primary, Guffroy, Magali, primary, Leal, Mauricio, primary, Falahatpisheh, Hadi, primary, Mathur, Divya, primary, Chen, Ting, primary, Kelleher, Kerry, primary, Khandke, Kiran, primary, Muszynska, Elwira, primary, Loganzo, Frank, primary, Rosfjord, Edward, primary, Lucas, Judy, primary, Kan, Zhengyan, primary, Subramanyam, Chakrapani, primary, O'Donnell, Christopher, primary, Neri, Dario, primary, Gerber, Hans-Peter, primary, May, Chad, primary, and Sapra, Puja, primary

Published
2023
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12. Supplementary Information from PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers

Author

Graziani, Edmund I., primary, Sung, Matthew, primary, Ma, Dangshe, primary, Narayanan, Bitha, primary, Marquette, Kimberly, primary, Puthenveetil, Sujiet, primary, Tumey, L. Nathan, primary, Bikker, Jack, primary, Casavant, Jeffrey, primary, Bennett, Eric M., primary, Charati, Manoj B., primary, Golas, Jonathon, primary, Hosselet, Christine, primary, Rohde, Cynthia M., primary, Hu, George, primary, Guffroy, Magali, primary, Falahatpisheh, Hadi, primary, Finkelstein, Martin, primary, Clark, Tracey, primary, Barletta, Frank, primary, Tchistiakova, Lioudmila, primary, Lucas, Judy, primary, Rosfjord, Edward, primary, Loganzo, Frank, primary, O'Donnell, Christopher J., primary, Gerber, Hans-Peter, primary, and Sapra, Puja, primary

Published
2023
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17. Data from Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions

Author

Damelin, Marc, primary, Bankovich, Alexander, primary, Park, Albert, primary, Aguilar, Jorge, primary, Anderson, Wade, primary, Santaguida, Marianne, primary, Aujay, Monette, primary, Fong, Sarah, primary, Khandke, Kiran, primary, Pulito, Virginia, primary, Ernstoff, Elana, primary, Escarpe, Paul, primary, Bernstein, Jeffrey, primary, Pysz, Marybeth, primary, Zhong, Wenyan, primary, Upeslacis, Erik, primary, Lucas, Judy, primary, Lucas, Justin, primary, Nichols, Timothy, primary, Loving, Kathryn, primary, Foord, Orit, primary, Hampl, Johannes, primary, Stull, Robert, primary, Barletta, Frank, primary, Falahatpisheh, Hadi, primary, Sapra, Puja, primary, Gerber, Hans-Peter, primary, and Dylla, Scott J., primary

Published
2023
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20. Supplementary Data from Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions

Author

Damelin, Marc, primary, Bankovich, Alexander, primary, Park, Albert, primary, Aguilar, Jorge, primary, Anderson, Wade, primary, Santaguida, Marianne, primary, Aujay, Monette, primary, Fong, Sarah, primary, Khandke, Kiran, primary, Pulito, Virginia, primary, Ernstoff, Elana, primary, Escarpe, Paul, primary, Bernstein, Jeffrey, primary, Pysz, Marybeth, primary, Zhong, Wenyan, primary, Upeslacis, Erik, primary, Lucas, Judy, primary, Lucas, Justin, primary, Nichols, Timothy, primary, Loving, Kathryn, primary, Foord, Orit, primary, Hampl, Johannes, primary, Stull, Robert, primary, Barletta, Frank, primary, Falahatpisheh, Hadi, primary, Sapra, Puja, primary, Gerber, Hans-Peter, primary, and Dylla, Scott J., primary

Published
2023
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23. Supplementary Figures 1-4 from Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions

Author

Damelin, Marc, primary, Bankovich, Alexander, primary, Park, Albert, primary, Aguilar, Jorge, primary, Anderson, Wade, primary, Santaguida, Marianne, primary, Aujay, Monette, primary, Fong, Sarah, primary, Khandke, Kiran, primary, Pulito, Virginia, primary, Ernstoff, Elana, primary, Escarpe, Paul, primary, Bernstein, Jeffrey, primary, Pysz, Marybeth, primary, Zhong, Wenyan, primary, Upeslacis, Erik, primary, Lucas, Judy, primary, Lucas, Justin, primary, Nichols, Timothy, primary, Loving, Kathryn, primary, Foord, Orit, primary, Hampl, Johannes, primary, Stull, Robert, primary, Barletta, Frank, primary, Falahatpisheh, Hadi, primary, Sapra, Puja, primary, Gerber, Hans-Peter, primary, and Dylla, Scott J., primary

Published
2023
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24. Adobe PDF - Supplementary_Data.pdf from Antitumor Efficacy Profile of PKI-402, a Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor

Author

Mallon, Robert, primary, Hollander, Irwin, primary, Feldberg, Larry, primary, Lucas, Judy, primary, Soloveva, Veronica, primary, Venkatesan, Aranapakam, primary, Dehnhardt, Christoph, primary, Delos Santos, Efren, primary, Chen, Zecheng, primary, dos Santos, Osvaldo, primary, Ayral-Kaloustian, Semiramis, primary, and Gibbons, Jay, primary

Published
2023
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27. Data from Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Author

Yu, Ker, primary, Toral-Barza, Lourdes, primary, Shi, Celine, primary, Zhang, Wei-Guo, primary, Lucas, Judy, primary, Shor, Boris, primary, Kim, Jamie, primary, Verheijen, Jeroen, primary, Curran, Kevin, primary, Malwitz, David J., primary, Cole, Derek C., primary, Ellingboe, John, primary, Ayral-Kaloustian, Semiramis, primary, Mansour, Tarek S., primary, Gibbons, James J., primary, Abraham, Robert T., primary, Nowak, Pawel, primary, and Zask, Arie, primary

Published
2023
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31. Data from Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

Author

Yu, Ker, primary, Shi, Celine, primary, Toral-Barza, Lourdes, primary, Lucas, Judy, primary, Shor, Boris, primary, Kim, Jae Eun, primary, Zhang, Wei-Guo, primary, Mahoney, Robert, primary, Gaydos, Christine, primary, Tardio, LuAnna, primary, Kim, Sung Kyoo, primary, Conant, Roger, primary, Curran, Kevin, primary, Kaplan, Joshua, primary, Verheijen, Jeroen, primary, Ayral-Kaloustian, Semiramis, primary, Mansour, Tarek S., primary, Abraham, Robert T., primary, Zask, Arie, primary, and Gibbons, James J., primary

Published
2023
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32. Supplementary Methods, Figures 1-2, Tables 1-2 from Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Author

Yu, Ker, primary, Toral-Barza, Lourdes, primary, Shi, Celine, primary, Zhang, Wei-Guo, primary, Lucas, Judy, primary, Shor, Boris, primary, Kim, Jamie, primary, Verheijen, Jeroen, primary, Curran, Kevin, primary, Malwitz, David J., primary, Cole, Derek C., primary, Ellingboe, John, primary, Ayral-Kaloustian, Semiramis, primary, Mansour, Tarek S., primary, Gibbons, James J., primary, Abraham, Robert T., primary, Nowak, Pawel, primary, and Zask, Arie, primary

Published
2023
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33. Supplementary Methods, Figures 1-5, Tables 1-2 from Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

Author

Yu, Ker, primary, Shi, Celine, primary, Toral-Barza, Lourdes, primary, Lucas, Judy, primary, Shor, Boris, primary, Kim, Jae Eun, primary, Zhang, Wei-Guo, primary, Mahoney, Robert, primary, Gaydos, Christine, primary, Tardio, LuAnna, primary, Kim, Sung Kyoo, primary, Conant, Roger, primary, Curran, Kevin, primary, Kaplan, Joshua, primary, Verheijen, Jeroen, primary, Ayral-Kaloustian, Semiramis, primary, Mansour, Tarek S., primary, Abraham, Robert T., primary, Zask, Arie, primary, and Gibbons, James J., primary

Published
2023
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37. Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Author

Eng, Christina H., Wang, Zuncai, Tkach, Diane, Toral-Barza, Lourdes, Ugwonali, Savuth, Liu, Shanming, Fitzgerald, Stephanie L., George, Elizabeth, Frias, Elizabeth, Cochran, Nadire, De Jesus, Rowena, McAllister, Gregory, Hoffman, Gregory R., Bray, Kevin, Lemon, LuAnna, Lucas, Judy, Fantin, Valeria R., Abraham, Robert T., Murphy, Leon O., and Nyfeler, Beat

Published
2016

38. Action Needed to Improve Compliance for Sport Fishing and Archery Imports.

Author

Lucas-Judy, Jessica

Subjects
EXCISE tax laws, SALES tax, INCOME tax, TAX administration & procedure, EXCISE tax, TAXPAYER compliance, WILDLIFE watching
Abstract

This report from the United States Government Accountability Office discusses the need for improved compliance with excise taxes on sport fishing and archery imports. The report highlights that consumer importers who purchase these products from foreign sellers may not be aware of their tax liability, and the IRS's guidance on these taxes is scattered and lacks necessary information. The report recommends that Congress consider making U.S. online marketplaces responsible for these taxes to improve collection efficiency. It also provides information on excise taxes in the United States, the challenges faced by consumer importers, and the efforts of federal agencies in collecting the taxes. [Extracted from the article]

Published
2024

39. Anti-Extra Domain B Splice Variant of Fibronectin Antibody–Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

Author

Hooper, Andrea T., primary, Marquette, Kimberly, additional, Chang, Chao-Pei Betty, additional, Golas, Jonathon, additional, Jain, Sadhana, additional, Lam, My-Hanh, additional, Guffroy, Magali, additional, Leal, Mauricio, additional, Falahatpisheh, Hadi, additional, Mathur, Divya, additional, Chen, Ting, additional, Kelleher, Kerry, additional, Khandke, Kiran, additional, Muszynska, Elwira, additional, Loganzo, Frank, additional, Rosfjord, Edward, additional, Lucas, Judy, additional, Kan, Zhengyan, additional, Subramanyam, Chakrapani, additional, O'Donnell, Christopher, additional, Neri, Dario, additional, Gerber, Hans-Peter, additional, May, Chad, additional, and Sapra, Puja, additional

Published
2022
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40. IRS Audit Selection Processes for Returns Claiming Refundable Credits Could Better Address Equity.

Author

Lucas-Judy, Jessica

Subjects
EARNED income tax credit, TAX auditing, MACHINE learning, AUDITING
Abstract

The United States Government Accountability Office (GAO) conducted a study on the Internal Revenue Service's (IRS) audit selection processes for returns claiming refundable credits. The study found concerns about unintended bias in the selection process and potential disparities in audit rates based on race and ethnicity. The GAO made six recommendations to the IRS to address these concerns and improve equity in audits. The IRS has agreed with the recommendations and has already taken steps to improve fairness and equity in audit case selection. [Extracted from the article]

Published
2024

43. PRIVATE DEBT COLLECTION PROGRAM: IRS Could Improve Results and Better Promote Equitable Outcomes for Taxpayers.

Author

Lucas-Judy, Jessica

Subjects
TAX assistance programs, COLLECTING of accounts, TAXATION, PUBLIC finance, INTERNAL revenue
Abstract

The article offers information on the Internal Revenue Service's (IRS) Private Debt Collection (PDC) program. Topics include the characteristics of taxpayers assigned to the program, allocation of recovered payments to IRS funds, and the lack of clear goals for fund management. Additionally, the article highlights the need for IRS to establish measurable standards to evaluate enforcement equity and address the exclusion of certain taxpayers from the program.

Published
2024

44. 2023 TAX FILING: IRS Improved Customer Service, but Could Further Improve Processing and Evaluate Expedited Hiring.

Author

Lucas-Judy, Jessica

Subjects
TAX assistance programs, CUSTOMER services, PERFORMANCE evaluation, FINANCIAL services industry taxation
Abstract

The article centers on the Internal Revenue Service's (IRS) activities during the 2023 tax filing season, emphasizing advancements in processing returns and a decreased backlog. Topics encompass the IRS's achievements in meeting processing time targets, persistent challenges in correspondence services, and the agency's strategies and outcomes related to hiring during the filing season.

Published
2024

47. Controversial criminal justice measures passed on legislature's final day

Author

Lucas, Judy

Subjects
Bills, Legislative -- Laws, regulations and rules, Parole -- Laws, regulations and rules, Government regulation, News, opinion and commentary, Sports and fitness
Abstract

Byline: Judy Lucas JEFFERSON CITY -- A second crime bill that has drawn plenty of opposition during the legislation session received final approval in the closing hours. The bill includes [...]

Published
2021

48. Lawmakers tack on COVID-19 amendments to higher education bill

Author

Lucas, Judy

Subjects
School facilities, Bills, Legislative, Education parks, Education, Higher, News, opinion and commentary, Sports and fitness
Abstract

Byline: Judy Lucas JEFFERSON CITY -- With time in the session running out, lawmakers have been hastily pushing COVID-19-related amendments onto bills set to be sent to the governor. During [...]

Published
2021

50. Bill makes gun stores essential businesses, expands concealed carry in churches

Author

Lucas, Judy

Subjects
Bills, Legislative, Firearms, Sporting goods stores, Firearms industry, News, opinion and commentary, Sports and fitness
Abstract

Byline: Judy Lucas JEFFERSON CITY -- Representatives on both sides of the aisle stacked gun-related amendments to a bill Monday that would expand residents' rights to carry and sell firearms. [...]

Published
2021

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