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Background: Atrial Fibrillation (AF) is associated with an increased risk of stroke and systemic embolism. Several studies have suggested that female AF patients could have a greater risk for stroke. There is scarce information about clinical characteristics and use of antithrombotic therapies in Latin American patients with nonvalvular AF. Objective: To describe the gender differences in clinical characteristics, thromboembolic risk, and antithrombotic therapy of patients with nonvalvular AF recruited in Mexico, an upper middle-income country, into the prospective national CARMEN-AF Registry. Methods: A total of 1423 consecutive patients, with at least one thromboembolic risk factor were enrolled in CARMEN-AF Registry during a three-year period (2014–2017). They were categorized according to Gender. Results: Overall, 48.6% were women, mean age 70 ± 12 years. Diabetes, smoking, alcoholism, non-ischemic cardiomyopathy, coronary artery disease, and obstructive sleep apnea were higher in men. Most women were found with paroxysmal AF (40.6%), and most men with permanent AF (44.0%). No gender differences were found in the use of vitamin K antagonists (VKA) (30.5% in women vs. 28.0% in men). No gender differences were found in the use of direct oral anticoagulants (DOAC) (33.8% women vs 35.4% men). Conclusions: CARMEN-AF Registry demonstrates that in Mexico, regardless of gender, a large proportion of patients remain undertreated. No gender differences were found in the use of VKA or DOAC. Keywords: Atrial fibrillation, Gender, Thromboembolic risk, Antithrombotic therapy, Stroke, Mexico

La principal causa de mortalidad en todo el mundo siguen siendo las enfermedades cardiovasculares, entre las que destacan por su frecuencia los síndromes coronarios agudos (SCA) contribuyen sustancialmente, a corto y largo plazo. Por tal motivo, las decisiones médicas que se toman en cada caso clínico, influyen notablemente en la función cardiaca del paciente y esto determina tanto la calidad de vida como la sobrevida en todos los enfermos. Presentamos un caso y la justificación que existe en la literatura médica de cómo hacer una buena práctica médica, orientada a mejor pronóstico. LUX MÉDICA AÑO 8, NÚMERO 24, MAYO

Uno de los principales objetivos de la metodología de enseñanza a distancia es precisamente posibilitar el acceso a estudios a personas que por sus circunstancias personales no habrían podido conseguirlos, como son las personas que tienen dificultades especiales para acceder a la enseñanza presencial. En el caso concreto del uso de medios educativos a través de Internet es evidente que la presentación de la información on-line ofrece muchas ventajas frente al papel. Es evidente que la innovación en el uso de la gestión de contenidos educativos y los formatos de especificación, logrando el mayor nivel de accesibilidad de los mismos, es uno de los aspectos más importantes para el desarrollo de la enseñanza a distancia en el momento actual. Este artículo muestra los avances que se pueden lograr con el uso de formatos contenedores para los recursos multimedia accesibles, lo cual redunda en una mejora de los actuales procesos de producción, distribución y mantenimiento de los contenidos y escenarios educativos, así como amortizar el esfuerzo realizado asegurando la mayor reutilización e interoperabilidad de los mismos.One of the main objectives of distance learning methodology is just providing access to studies to people who are not able to get access to face-to-face course delivery, such as people with disabilities. The use of educational media through the Internet offers clearly many advantages over traditional text based materials. For example, people with visual impairments can increase the font size on the screen, easily improve the contrast of the image, change colors, etc. Therefore, computers allow people with disabilities to perform activities that would have been much more difficult with traditional technology and enables them to access services previously closed to them. Therefore innovation in the management of accessible educational content and new formats or specifications achieving the highest level of accessibility is nowadays one of the most important aspects for the development of distance learning. This article demonstrates the progress that can be achieved using container formats for multimedia resources, resulting in an improvement of existing production processes, distribution, and maintenance ensuring their reusability and interoperability.