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11. International Society for Therapeutic Ultrasound Conference 2016

Author

Fowlkes, Brian, Ghanouni, Pejman, Sanghvi, Narendra, Coussios, Constantin, Lyon, Paul C., Gray, Michael, Mannaris, Christophoros, Victor, Marie de Saint, Stride, Eleanor, Cleveland, Robin, Carlisle, Robert, Wu, Feng, Middleton, Mark, Gleeson, Fergus, Aubry, Jean-Franҫois, Pauly, Kim Butts, Moonen, Chrit, Vortman, Jacob, Sharabi, Shirley, Daniels, Dianne, Last, David, Guez, David, Levy, Yoav, Volovick, Alexander, Grinfeld, Javier, Rachmilevich, Itay, Amar, Talia, Zibly, Zion, Mardor, Yael, Harnof, Sagi, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Naor, Omer, Farah, Nairouz, Paeng, Dong-Guk, Xu, Zhiyuan, Snell, John, Quigg, Anders H., Eames, Matthew, Jin, Changzhu, Everstine, Ashli C., Sheehan, Jason P., Lopes, Beatriz S., Kassell, Neal, Looi, Thomas, Khokhlova, Vera, Mougenot, Charles, Hynynen, Kullervo, Drake, James, Slayton, Michael, Amodei, Richard C., Compton, Keegan, McNelly, Ashley, Latt, Daniel, Kearney, John, Melodelima, David, Dupre, Aurelien, Chen, Yao, Perol, David, Vincenot, Jeremy, Chapelon, Jean-Yves, Rivoire, Michel, Guo, Wei, Ren, Guoxin, Shen, Guofeng, Neidrauer, Michael, Zubkov, Leonid, Weingarten, Michael S., Margolis, David J., Lewin, Peter A., McDannold, Nathan, Sutton, Jonathan, Vykhodtseva, Natalia, Livingstone, Margaret, Kobus, Thiele, Zhang, Yong-Zhi, Schwartz, Michael, Huang, Yuexi, Lipsman, Nir, Jain, Jennifer, Chapman, Martin, Sankar, Tejas, Lozano, Andres, Yeung, Robert, Damianou, Christakis, Papadopoulos, Nikolaos, Brokman, Omer, Zadicario, Eyal, Brenner, Ori, Castel, David, Wu, Shih-Ying, Grondin, Julien, Zheng, Wenlan, Heidmann, Marc, Karakatsani, Maria Eleni, Sánchez, Carlos J. Sierra, Ferrera, Vincent, Konofagou, Elisa E., Yiannakou, Marinos, Cho, HongSeok, Lee, Hwayoun, Han, Mun, Choi, Jong-Ryul, Lee, Taekwan, Ahn, Sanghyun, Chang, Yongmin, Park, Juyoung, Ellens, Nicholas, Partanen, Ari, Farahani, Keyvan, Airan, Raag, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Lafon, Cyril, Delattre, Jean-yves, Idbaih, Ahmed, Odéen, Henrik, Bolster, Bradley, Jeong, Eun Kee, Parker, Dennis L., Gaur, Pooja, Feng, Xue, Fielden, Samuel, Meyer, Craig, Werner, Beat, Grissom, William, Marx, Michael, Weber, Hans, Taviani, Valentina, Hargreaves, Brian, Tanaka, Jun, Kikuchi, Kentaro, Ishijima, Ayumu, Azuma, Takashi, Minamihata, Kosuke, Yamaguchi, Satoshi, Nagamune, Teruyuki, Sakuma, Ichiro, Takagi, Shu, Santin, Mathieu D., Marsac, Laurent, Maimbourg, Guillaume, Monfort, Morgane, Larrat, Benoit, François, Chantal, Lehéricy, Stéphane, Tanter, Mickael, Samiotaki, Gesthimani, Wang, Shutao, Acosta, Camilo, Feinberg, Eliza R., Kovacs, Zsofia I., Tu, Tsang-Wei, Papadakis, Georgios Z., Reid, William C., Hammoud, Dima A., Frank, Joseph A., Kovacs, Zsofia i., Kim, Saejeong, Jikaria, Neekita, Bresler, Michele, Qureshi, Farhan, Xia, Jingjing, Tsui, Po-Shiang, Liu, Hao-Li, Plata, Juan C., Sveinsson, Bragi, Salgaonkar, Vasant A., Adams, Matthew, Diederich, Chris, Ozhinsky, Eugene, Bucknor, Matthew D., Rieke, Viola, Mikhail, Andrew, Severance, Lauren, Negussie, Ayele H., Wood, Bradford, de Greef, Martijn, Schubert, Gerald, Ries, Mario, Poorman, Megan E., Dockery, Mary, Chaplin, Vandiver, Dudzinski, Stephanie O., Spears, Ryan, Caskey, Charles, Giorgio, Todd, Costa, Marcia M., Papaevangelou, Efthymia, Shah, Anant, Rivens, Ian, Box, Carol, Bamber, Jeff, ter Haar, Gail, Burks, Scott R., Nagle, Matthew, Nguyen, Ben, Milo, Blerta, Le, Nhan M., Song, Shaozhen, Zhou, Kanheng, Nabi, Ghulam, Huang, Zhihong, Ben-Ezra, Shmuel, Rosen, Shani, Mihcin, Senay, Strehlow, Jan, Karakitsios, Ioannis, Le, Nhan, Schwenke, Michael, Demedts, Daniel, Prentice, Paul, Haase, Sabrina, Preusser, Tobias, Melzer, Andreas, Mestas, Jean-Louis, Chettab, Kamel, Gomez, Gustavo Stadthagen, Dumontet, Charles, Werle, Bettina, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Quesson, Bruno, Livneh, Amit, Adam, Dan, Robin, Justine, Arnal, Bastien, Fink, Mathias, Pernot, Mathieu, Khokhlova, Tatiana D., Schade, George R., Wang, Yak-Nam, Kreider, Wayne, Simon, Julianna, Starr, Frank, Karzova, Maria, Maxwell, Adam, Bailey, Michael R., Lundt, Jonathan E., Allen, Steven P., Sukovich, Jonathan R., Hall, Timothy, Xu, Zhen, May, Philip, Lin, Daniel W., Constans, Charlotte, Deffieux, Thomas, Aubry, Jean-Francois, Park, Eun-Joo, Ahn, Yun Deok, Kang, Soo Yeon, Park, Dong-Hyuk, Lee, Jae Young, Vidal-Jove, J., Perich, E., Ruiz, A., Jaen, A., Eres, N., del Castillo, M. Alvarez, Myers, Rachel, Kwan, James, Coviello, Christian, Rowe, Cliff, Crake, Calum, Finn, Sean, Jackson, Edward, Pouliopoulos, Antonios, Li, Caiqin, Tinguely, Marc, Tang, Meng-Xing, Garbin, Valeria, Choi, James J., Folkes, Lisa, Stratford, Michael, Nwokeoha, Sandra, Li, Tong, Farr, Navid, D’Andrea, Samantha, Gravelle, Kayla, Chen, Hong, Lee, Donghoon, Hwang, Joo Ha, Tardoski, Sophie, Ngo, Jacqueline, Gineyts, Evelyne, Roux, Jean-Pau, Clézardin, Philippe, Conti, Allegra, Magnin, Rémi, Gerstenmayer, Matthieu, Lux, François, Tillement, Olivier, Mériaux, Sébastien, Penna, Stefania Della, Romani, Gian Luca, Dumont, Erik, Sun, Tao, Power, Chanikarn, Miller, Eric, Sapozhnikov, Oleg, Tsysar, Sergey, Yuldashev, Petr V., Svet, Victor, Li, Dongli, Pellegrino, Antonio, Petrinic, Nik, Siviour, Clive, Jerusalem, Antoine, Yuldashev, Peter V., Cunitz, Bryan W., Dunmire, Barbrina, Inserra, Claude, Guedra, Matthieu, Mauger, Cyril, Gilles, Bruno, Solovchuk, Maxim, Sheu, Tony W. H., Thiriet, Marc, Zhou, Yufeng, Neufeld, Esra, Baumgartner, Christian, Payne, Davnah, Kyriakou, Adamos, Kuster, Niels, Xiao, Xu, McLeod, Helen, Dillon, Christopher, Payne, Allison, Khokhova, Vera A., Sinilshchikov, Ilya, Andriyakhina, Yulia, Rybyanets, Andrey, Shvetsova, Natalia, Berkovich, Alex, Shvetsov, Igor, Shaw, Caroline J., Civale, John, Giussani, Dino, Lees, Christoph, Ozenne, Valery, Toupin, Solenn, Salgaonkar, Vasant, Kaye, Elena, Monette, Sebastien, Maybody, Majid, Srimathveeravalli, Govindarajan, Solomon, Stephen, Gulati, Amitabh, Bezzi, Mario, Jenne, Jürgen W., Lango, Thomas, Müller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Günther, Matthias, Dinh, Au Hoang, Niaf, Emilie, Bratan, Flavie, Guillen, Nicolas, Souchon, Rémi, Lartizien, Carole, Crouzet, Sebastien, Rouviere, Olivier, Han, Yang, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, van Breugel, Johanna M., van den Bosch, Maurice A., Fellah, Benjamin, Le Bihan, Denis, Hernandez-Garcia, Luis, Cain, Charles A., Lyka, Erasmia, Elbes, Delphine, Li, Chunhui, Tamano, Satoshi, Jimbo, Hayato, Yoshizawa, Shin, Fujiwara, Keisuke, Itani, Kazunori, Umemura, Shin-ichiro, Stoianovici, Dan, Zaini, Zulfadhli, Takagi, Ryo, Zong, Shenyan, Watkins, Ron, Pascal-Tenorio, Aurea, Jones, Peter, Butts-Pauly, Kim, Bouley, Donna, Chen, Yazhu, Lin, Chung-Yin, Hsieh, Han-Yi, Wei, Kuo-Chen, Garnier, Camille, Renault, Gilles, Seifabadi, Reza, Wilson, Emmanuel, Eranki, Avinash, Kim, Peter, Lübke, Dennis, Huber, Peter, Georgii, Joachim, Dresky, Caroline V., Haller, Julian, Yarmolenko, Pavel, Sharma, Karun, Celik, Haydar, Li, Guofeng, Qiu, Weibao, Zheng, Hairong, Tsai, Meng-Yen, Chu, Po-Chun, Webb, Taylor, Vyas, Urvi, Walker, Matthew, Zhong, Jidan, Waspe, Adam C., Hodaie, Mojgan, Yang, Feng-Yi, Huang, Sin-Luo, Zur, Yuval, Assif, Benny, Aurup, Christian, Kamimura, Hermes, Carneiro, Antonio A., Rothlübbers, Sven, Schwaab, Julia, Houston, Graeme, Azhari, Haim, Weiss, Noam, Sosna, Jacob, Goldberg, S. Nahum, Barrere, Victor, Jang, Kee W., Lewis, Bobbi, Wang, Xiaotong, Suomi, Visa, Edwards, David, Larrabee, Zahary, Hananel, Arik, Rafaely, Boaz, Debbiny, Rasha Elaimy, Dekel, Carmel Zeltser, Assa, Michael, Menikou, George, Mouratidis, Petros, Pineda-Pardo, José A., de Pedro, Marta Del Álamo, Martinez, Raul, Hernandez, Frida, Casas, Silvia, Oliver, Carlos, Pastor, Patricia, Vela, Lidia, Obeso, Jose, Greillier, Paul, Zorgani, Ali, Catheline, Stefan, Solovov, Vyacheslav, Vozdvizhenskiy, Michael O., Orlov, Andrew E., Wu, Chueh-Hung, Sun, Ming-Kuan, Shih, Tiffany T., Chen, Wen-Shiang, Prieur, Fabrice, Pillon, Arnaud, Cartron, Valerie, Cebe, Patrick, Chansard, Nathalie, Lafond, Maxime, Seya, Pauline Muleki, Bera, Jean-Christophe, Boissenot, Tanguy, Fattal, Elias, Bordat, Alexandre, Chacun, Helene, Guetin, Claire, Tsapis, Nicolas, Maruyama, Kazuo, Unga, Johan, Suzuki, Ryo, Fant, Cécile, Rogez, Bernadette, Afadzi, Mercy, Myhre, Ola Finneng, Vea, Siri, Bjørkøy, Astrid, Yemane, Petros Tesfamichael, van Wamel, Annemieke, Berg, Sigrid, Hansen, Rune, Angelsen, Bjørn, and Davies, Catharina

Subjects
Meeting Abstracts
Published
2017

12. 5th International Symposium on Focused Ultrasound

Author

Abounader, Roger, Abraham, Christopher, Adema, Gosse, Agrawal, Punit, Airan, Raag, Aleman, Dionne, Alexander, Phillip, Alkins, Ryan, Alnazeer, Moez, Altman, Michael, Aly, Amirah, Amaral, Joao G., Amrahli, Maral, Amraoui, Sana, Andarawewa, Kumari, Andriyakhina, Yulia, Angstadt, Mary, Ankou, Bénédicte, Arias, Ana C., Arvanitis, Costas, Asadnia, Kiana, Aubert, Isabelle, Aubry, Jean-Francois, Aurup, Christian, Bader, Kenneth, Badr, Lena, Baek, Hongchae, Barbato, Gaetano, Beccaria, Kevin, Bellorofonte, Carlo, Benson, Lee, Bernus, Olivier, Berriet, Rémi, Bertolina, Jim, Beskin, Viktoriya, Bessière, Francis, Bethune, Allison, Bezzi, Mario, Bond, Aaron, Bonomo, Guido, Borowsky, Alexander, Borys, Nicolas, Böttcher, Joachim, Bouley, Donna, Bour, Pierre, Bourekas, Eric, Brenin, David, Brokman, Omer, Brosh, Inbar, Buckner, Andrew, Bullock, Timothy, Cafarelli, Andrea, Cahill, Jessica, Camarena, Francisco, Camelo-Piragua, Sandra, Campbell, Benjamin, Campbell, Fiona, Cannata, Jon, Canney, Michael, Carlson, Roy, Carneiro, Antonio, Carpentier, Alexandre, Catheline, Stefan, Cavin, Ian, Cesana, Claudio, Chabok, Hamid R., Chamanara, Marzieh, Chang, Jin H., Chang, Won S., Changizi, Barbara, Chapelon, Jean Y., Chaplin, Vandiver, Chapman, Martin, Chaudhary, Neeraj, Chaussy, Christian, Chen, Cherry, Chen, Johnny, Chen, Wohsing, Chen, Xiaoming, Chevalier, Philippe, Chiou, George, Chisholm, Alexander, Christofferson, Ivy, Chung, Hyun H., Ciuti, Gastone, Clement, Gregory, Cooper, Mark, Corea, Joseph, Corso, Cristiano, Cosman, Josh, Coughlin, Dezba, Crake, Calum, Cunitz, Bryan, Curiel, Laura, Curley, Colleen T., Czarnota, Gregory, Dababou, Susan, Dallapiazza, Robert, de Bever, Joshua, de Jager, Bram, de Ruiter, Joost, de Senneville, Baudouin D., Deckers, Roel, Delattre, Jean-Yves, den Brok, Martijn, Dhanaliwala, Ali, Diodato, Alessandro, Dixon, Adam, Donner, Elizabeth, Downs, Matthew, Du, Zhongmin, Dubois, Rémi, Dupre, Aurelien, Eikelenboom, Dylan, Elias, W. J., Ellens, Nicholas, Endre, Ruby, Eran, Ayelet, Erasmus, Hans-Peter, Everstine, Ashli, Farahani, Keyvan, Farrer, Alexis, Farry, Justin, Federau, Christian, Feng, Xue, Ferrer, Cyril, Ferrera, Vincent, Fishman, Paul, Foley, Jessica, Frenkel, Victor, Fütterer, Jurgen, Gach, H. M., Gandhi, Dheeraj, Gertner, Michael, Goldsher, Dorit, Gorgone, Alessandro, Greillier, Paul, Griesenauer, Rebekah, Grissom, William, Grondin, Julien, Guha, Chandan, Gulati, Amitabh, Gullapalli, Rao, Guo, Sijia, Gupta, Samit, Gurm, Hitinder, Gwinn, Ryder, Hadley, Rock, Haïssaguerre, Michel, Hammoud, Dima, Hananel, Arik, Hargrove, Amelia, Hatch, Robert, Haworth, Kevin, Hazan, Eilon, He, Ye, Heemels, Maurice, Heerschap, Arend, Hilas, Elaine, Hoang-Xuan, Khe, Hocini, Mélèze, Hodaie, Mojgan, Hofmann, Denis, Holland, Christy, Hoogenboom, Martijn, Hopyan, Sevan, Hossack, John, Houdouin, Alexandre, Hsu, Po-Hung, Hu, Jim, Hurwitz, Mark, Huss, Diane, Hwang, Chang-il, Hwang, Joo H., Idbaih, Ahmed, Ikeuchi, Masahiko, Ingham, Elizabeth, Ives, Kimberly, Izumi, Masashi, Jackson-Lewis, Vernice, Janát-Amsbury, Margit, Jang, Kee W., Jedruszczuk, Kathleen, Jiménez-Gambín, Sergio, Jiménez, Noé, Johnson, Sara, Jonathan, Sumeeth, Joy, Joyce, Jung, Hyun H., Jung, Na Y., Kahn, Itamar, Kamimura, Hermes, Kamrava, Seyed K., Kang, Jeeun, Kang, Kook J., Kang, Soo Y., Kao, Yi-tzu, Katti, Prateek, Kawasaki, Motohiro, Kaye, Elena, Keupp, Jochen, Kim, AeRang, Kim, Harry, Kim, Hyun-Chul, Kim, Hyuncheol, Kim, Hyungmin, Kim, Min S., Kim, Namho, Kiyasu, Katsuhito, Kneepkens, Esther, Knopp, Michael, Kobus, Thiele, Koral, Korgun, Kreider, Wayne, Krishna, Vibhor, Krug, Roland, Krupa, Steve, Kuo, Chia-Chun, Kwiecinski, Wojciech, Lacoste, Romain, Lam, Heather, Lamberti-Pasculli, Maria, Lang, Brian, Larner, James, Larrabee, Zachary, Leach, J. K., LeBlang, Suzanne, Leclercq, Delphine, Lee, Hak J., Lee, Jong-Hwan, Lehericy, Stéphane, Leighton, Wan, Leung, Steven, Lewis, Bobbi, Lewis, Matthew, Li, Dawei, Linn, Sabine, Lipsman, Nir, Liu, Hao-Li, Liu, Jingfei, Lopes, M. B., Lotz, Jeff, Lu, Xin, Lundt, Jonathan, Luo, Xi, Lustgarten, Lior, Lustig, Micheal, Macoskey, Jonathan, Madore, Bruno, Maev, Roman, Magat, Julie, Maimbourg, Guillaume, Maimon, Noam, Mainprize, Todd, Malayer, Jerry, Maples, Danny, Marquet, Fabrice, Marrocchio, Cristina, Marx, Mike, Mastorakos, Panagiotis, Mauri, Giovanni, McLean, Hailey, McMichael, John, Mead, Brian P., Melodelima, David, Melot-Dusseau, Sandrine, Menciassi, Arianna, Merrill, Robb, Meyer, Joshua, Midiri, Massimo, Miga, Michael, Migliore, Ilaria G., Miller, Eric, Minalga, Emilee, Moon, Hyungwon, Moore, David, Mourad, Pierre, Mouratidis, Petros, Mueller, Michael, Mugler, John, Muller, Sébastien, Namba, Hirofumi, Naor, Omer, Nassar, Maria, Nazai, Navid, Negron, Karina, Negussie, Ayele, Nguyen, Thai-Son, Nicolay, Klaas, Nikolaeva, Anastasia V., Oetgen, Matthew, Olive, Kenneth, Olumolade, Oluyemi, Orsi, Franco, Owens, Gabe, Ozilgen, Arda, Padegimas, Linas, Palermo, Carmine, Pan, Chia-Hsin, Pandey, Aditya, Papadakis, Georgios, Park, Chang K., Park, Sang M., Parker, Jonathon, Parvizi, Mohammad H., Pascal-Tenorio, Aurea, Patel, Janish, Patz, Sam, Payen, Thomas, Perich, Eloi, Pernot, Mathieu, Perol, David, Perry, James, Pillarisetty, Venu, Pioche, Mathieu, Pizzuto, Matthew, Plaksin, Michael, Plata, Juan, Price, Karl, Prince, Jessica, Przedborski, Serge, Quinones-Hinojosa, Alfredo, Ramachandran, Akhilesh, Ranjan, Ashish, Ravikumar, Vinod, Reichenbach, Juergen, Repasky, Elizabeth, Rezai, Ali, Ritter, Philippe, Rivoire, Michel, Rochman, Carrie, Rosenberg, Jarrett, Rosnitskiy, Pavel B., Ruiz, Antonio, Sahgal, Arjun, Samiotaki, Gesthimani, Sanghvi, Narendra, Santin, Mathieu D., Santos, Domiciano, Sasaki, Noboru, Sastra, Steve, Schade, George, Schall, Jeffrey, Schlesinger, Ilana, Schmitt, Paul, Schwaab, Julia, Scionti, Stephen, Scipione, Roberto, Scoarughi, Gian L., Scott, Serena, Sebeke, Lukas, Seifabadi, Reza, Seo, Jai, Sesenoglu-Laird, Ozge, Shah, Binit, Shahriari, Kian, Shaikh, Sumbul, Shea, Jill, Shi, Jiaqi, Shim, Jenny, Shinkov, Alexander, Shuman, Jillian, Silvestrini, Matthew, Sim, Changbeom, Sin, Vivian, Sinai, Alon, Singh, Manoj, Sinilshchikov, Ilya, Skalina, Karin, Slingluff, Craig, So, Po-Wah, Solomon, Stephen, Son, Keon H., Sperling, Scott, Stein, Ruben, Stein, Sherman, Stevens, Aaron, Stimec, Jennifer, Storm, Gert, Straube, William, Suelmann, Britt, Sutton, Jonathan, Svedin, Bryant, Takemasa, Ryuichi, Takiguchi, Mitsuyoshi, Tam, Emily, Tan, Jeremy, Tang, Xinyan, Tanter, Mickael, Tebebi, Pamela, Tehrani, Seruz, Temple, Michael, Teofilovic, Dejan, ter Haar, Gail, Terzi, Marina E., Thueroff, Stefan, Timbie, Kelsie, Tognarelli, Selene, Tretbar, Steffen, Trudeau, Maureen, Tsai, Yi-Chieh, Tsysar, Sergey A., Tucci, Samantha, Tuveson, David, Ushida, Takahiro, Vaessen, Paul, Vaillant, Fanny, Van Arsdell, Glen, van Breugel, Johanna, Van der Jeugd, Anneke, Van der Wall, Elsken, van Diest, Paul, van Stralen, Marijn, Varano, Gianluca, Velat, Manuela, Vidal-Jove, Joan, Vigna, Paolo D., Vignot, Alexandre, Vincenot, Jeremy, Vykhodtseva, Natalia, Wang, Bin, Wang, Han, Wang, Kevin, Wang, Qi, Wang, Qingguo, Wang, Shengping, Wang, Yak-Nam, Wang, Zhaorui, Wardlow, Rachel, Warren, Amy, Waszczak, Barbara, Watson, Katherine, Webb, Taylor, Wei-Bin, Shen, Wei, Kuo-Chen, Weiss, Steffen, Weissler, Yoni, Werner, Beat, Wesseling, Pieter, Williams, Noelle, Wilson, Emmanuel, Wintermark, Max, Witkamp, Arjen, Wong, Carlos, Wu, Jing-Fu, Wydra, Adrian, Xu, Alexis, Xu, Doudou, Xu, Su, Yang, Georgiana, Yang, Nai-Yi, Yao, Chen, Yarowsky, Paul, Ye, Patrick P., Yuldashev, Petr, Zaaroor, Menashe, Zachiu, Cornel, Zahos, Peter, Zangos, Stephan, Zhang, Dandan, Zhang, Hua, Zhang, Jimin, Zhang, Junhai, Zhang, Xi, Zhao, Li, Zhong, Pei, Zhuo, Jiachen, Zidowitz, Stephan, Zinke, Wolf, Zorgani, Ali, and Aerospace and Ocean Engineering

Subjects
GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

Published version

Published
2016

13. Histotripsy for Non-Invasive Ablation of Hepatocellular Carcinoma (HCC) Tumor in a Subcutaneous Xenograft Murine Model

Author

Worlikar, Tejaswi, primary, Vlaisavljevich, Eli, additional, Gerhardson, Tyler, additional, Greve, Joan, additional, Wan, Shanshan, additional, Kuruvilla, Sibu, additional, Lundt, Jonathan, additional, Ives, Kimberly, additional, Hall, Timothy, additional, Welling, Theodore H., additional, Lee, Fred, additional, and Xu, Zhen, additional

Published
2018
Full Text
View/download PDF

14. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, primary, Sinai, Alon, additional, Goldsher, Dorit, additional, Eran, Ayelet, additional, Nassar, Maria, additional, Schlesinger, Ilana, additional, Parker, Jonathon, additional, Ravikumar, Vinod, additional, Ghanouni, Pejman, additional, Stein, Sherman, additional, Halpern, Casey, additional, Krishna, Vibhor, additional, Hargrove, Amelia, additional, Agrawal, Punit, additional, Changizi, Barbara, additional, Bourekas, Eric, additional, Knopp, Michael, additional, Rezai, Ali, additional, Mead, Brian, additional, Kim, Namho, additional, Mastorakos, Panagiotis, additional, Suk, Jung Soo, additional, Miller, Wilson, additional, Klibanov, Alexander, additional, Hanes, Justin, additional, Price, Richard, additional, Wang, Shutao, additional, Olumolade, Oluyemi, additional, Kugelman, Tara, additional, Jackson-Lewis, Vernice, additional, Karakatsani, Maria Eleni, additional, Han, Yang, additional, Przedborski, Serge, additional, Konofagou, Elisa, additional, Hynynen, Kullervo, additional, Aubert, Isabelle, additional, Leinenga, Gerhard, additional, Nisbet, Rebecca, additional, Hatch, Robert, additional, Van der Jeugd, Anneke, additional, Evans, Harrison, additional, Götz, Jürgen, additional, Van der Jeugd, Ann, additional, Fishman, Paul, additional, Yarowsky, Paul, additional, Frenkel, Victor, additional, Wei-Bin, Shen, additional, Nguyen, Ben, additional, Sanchez, Carlos Sierra, additional, Acosta, Camilo, additional, Chen, Cherry, additional, Wu, Shih-Ying, additional, Aryal, Muna, additional, Papademetriou, Iason T., additional, Zhang, Yong-Zhi, additional, Power, Chanikarn, additional, McDannold, Nathan, additional, Porter, Tyrone, additional, Kovacs, Zsofia, additional, Kim, Saejeong, additional, Jikaria, Neekita, additional, Qureshi, Farhan, additional, Bresler, Michele, additional, Frank, Joseph, additional, Odéen, Henrik, additional, Chiou, George, additional, Snell, John, additional, Todd, Nick, additional, Madore, Bruno, additional, Parker, Dennis, additional, Pauly, Kim Butts, additional, Marx, Mike, additional, Jonathan, Sumeeth, additional, Grissom, William, additional, Arvanitis, Costas, additional, Clement, Gregory, additional, de Bever, Joshua, additional, Payne, Allison, additional, Christensen, Douglas, additional, Maimbourg, Guillaume, additional, Santin, Mathieu David, additional, Houdouin, Alexandre, additional, Lehericy, Stéphane, additional, Tanter, Mickael, additional, Aubry, Jean Francois, additional, Federau, Christian, additional, Werner, Beat, additional, Paeng, Dong-Guk, additional, Xu, Zhiyuan, additional, Quigg, Anders, additional, Eames, Matt, additional, Jin, Changzhu, additional, Everstine, Ashli, additional, Sheehan, Jason, additional, Lopes, M. Beatriz, additional, Kassell, Neal, additional, Drake, James, additional, Price, Karl, additional, Lustgarten, Lior, additional, Sin, Vivian, additional, Mougenot, Charles, additional, Donner, Elizabeth, additional, Tam, Emily, additional, Hodaie, Mojgan, additional, Waspe, Adam, additional, Looi, Thomas, additional, Pichardo, Samuel, additional, Lee, Wonhye, additional, Chung, Yong An, additional, Jung, Yujin, additional, Song, In-Uk, additional, Yoo, Seung-Schik, additional, Kim, Hyun-Chul, additional, Lee, Jong-Hwan, additional, Caskey, Charles, additional, Zinke, Wolf, additional, Cosman, Josh, additional, Shuman, Jillian, additional, Schall, Jeffrey, additional, Aurup, Christian, additional, Chen, Hong, additional, Kamimura, Hermes, additional, Carneiro, Antonio, additional, Sun, Tao, additional, Nazai, Navid, additional, Patz, Sam, additional, Livingstone, Margaret, additional, Mainprize, Todd, additional, Huang, Yuexi, additional, Alkins, Ryan, additional, Chapman, Martin, additional, Perry, James, additional, Lipsman, Nir, additional, Bethune, Allison, additional, Sahgal, Arjun, additional, Trudeau, Maureen, additional, Liu, Hao-Li, additional, Hsu, Po-Hung, additional, Wei, Kuo-Chen, additional, Sutton, Jonathan, additional, Alexander, Phillip, additional, Miller, Eric, additional, Kobus, Thiele, additional, Carpentier, Alexandre, additional, Canney, Michael, additional, Vignot, Alexandre, additional, Beccaria, Kevin, additional, Leclercq, Delphine, additional, Lafon, Cyril, additional, Chapelon, Jean Yves, additional, Hoang-Xuan, Khe, additional, Delattre, Jean-Yves, additional, Idbaih, Ahmed, additional, Moore, David, additional, Xu, Alexis, additional, Schmitt, Paul, additional, Foley, Jessica, additional, Sukovich, Jonathan, additional, Cain, Charles, additional, Pandey, Aditya, additional, Chaudhary, Neeraj, additional, Camelo-Piragua, Sandra, additional, Allen, Steven, additional, Cannata, Jon, additional, Teofilovic, Dejan, additional, Bertolina, Jim, additional, Hall, Timothy, additional, Xu, Zhen, additional, Grondin, Julien, additional, Ferrera, Vincent, additional, ter Haar, Gail, additional, Mouratidis, Petros, additional, Repasky, Elizabeth, additional, Timbie, Kelsie, additional, Badr, Lena, additional, Campbell, Benjamin, additional, McMichael, John, additional, Buckner, Andrew, additional, Prince, Jessica, additional, Stevens, Aaron, additional, Bullock, Timothy, additional, Skalina, Karin, additional, Guha, Chandan, additional, Orsi, Franco, additional, Bonomo, Guido, additional, Vigna, Paolo Della, additional, Mauri, Giovanni, additional, Varano, Gianluca, additional, Schade, George, additional, Wang, Yak-Nam, additional, Pillarisetty, Venu, additional, Hwang, Joo Ha, additional, Khokhlova, Vera, additional, Bailey, Michael, additional, Khokhlova, Tatiana, additional, Sinilshchikov, Ilya, additional, Yuldashev, Petr, additional, Andriyakhina, Yulia, additional, Kreider, Wayne, additional, Maxwell, Adam, additional, Sapozhnikov, Oleg, additional, Partanen, Ari, additional, Lundt, Jonathan, additional, Preusser, Tobias, additional, Haase, Sabrina, additional, Bezzi, Mario, additional, Jenne, Jürgen, additional, Langø, Thomas, additional, Midiri, Massimo, additional, Mueller, Michael, additional, Sat, Giora, additional, Tanner, Christine, additional, Zangos, Stephan, additional, Guenther, Matthias, additional, Melzer, Andreas, additional, Menciassi, Arianna, additional, Tognarelli, Selene, additional, Cafarelli, Andrea, additional, Diodato, Alessandro, additional, Ciuti, Gastone, additional, Rothluebbers, Sven, additional, Schwaab, Julia, additional, Strehlow, Jan, additional, Mihcin, Senay, additional, Tretbar, Steffen, additional, Payen, Thomas, additional, Palermo, Carmine, additional, Sastra, Steve, additional, Olive, Kenneth, additional, Adams, Matthew, additional, Salgaonkar, Vasant, additional, Scott, Serena, additional, Sommer, Graham, additional, Diederich, Chris, additional, Vidal-Jove, Joan, additional, Perich, Eloi, additional, Ruiz, Antonio, additional, Velat, Manuela, additional, Melodelima, David, additional, Dupre, Aurelien, additional, Vincenot, Jeremy, additional, Yao, Chen, additional, Perol, David, additional, Rivoire, Michel, additional, Tucci, Samantha, additional, Mahakian, Lisa, additional, Fite, Brett, additional, Ingham, Elizabeth, additional, Tam, Sarah, additional, Hwang, Chang-il, additional, Tuveson, David, additional, Ferrara, Katherine, additional, Scionti, Stephen, additional, Chen, Lili, additional, Cvetkovic, Dusica, additional, Chen, Xiaoming, additional, Gupta, Roohi, additional, Wang, Bin, additional, Ma, Charlie, additional, Bader, Kenneth, additional, Haworth, Kevin, additional, Holland, Christy, additional, Sanghvi, Narendra, additional, Carlson, Roy, additional, Chen, Wohsing, additional, Chaussy, Christian, additional, Thueroff, Stefan, additional, Cesana, Claudio, additional, Bellorofonte, Carlo, additional, Wang, Qingguo, additional, Wang, Han, additional, Wang, Shengping, additional, Zhang, Junhai, additional, Bazzocchi, Alberto, additional, Napoli, Alessandro, additional, Staruch, Robert, additional, Bing, Chenchen, additional, Shaikh, Sumbul, additional, Nofiele, Joris, additional, Szczepanski, Debra, additional, Staruch, Michelle Wodzak, additional, Williams, Noelle, additional, Laetsch, Theodore, additional, Chopra, Rajiv, additional, Rosenberg, Jarrett, additional, Bitton, Rachelle, additional, LeBlang, Suzanne, additional, Meyer, Joshua, additional, Hurwitz, Mark, additional, Yarmolenko, Pavel, additional, Celik, Haydar, additional, Eranki, Avinash, additional, Beskin, Viktoriya, additional, Santos, Domiciano, additional, Patel, Janish, additional, Oetgen, Matthew, additional, Kim, AeRang, additional, Kim, Peter, additional, Sharma, Karun, additional, Chisholm, Alexander, additional, Aleman, Dionne, additional, Scipione, Roberto, additional, Temple, Michael, additional, Amaral, Joao Guilherme, additional, Endre, Ruby, additional, Lamberti-Pasculli, Maria, additional, de Ruiter, Joost, additional, Campbell, Fiona, additional, Stimec, Jennifer, additional, Gupta, Samit, additional, Singh, Manoj, additional, Hopyan, Sevan, additional, Czarnota, Gregory, additional, Brenin, David, additional, Rochman, Carrie, additional, Kovatcheva, Roussanka, additional, Vlahov, Jordan, additional, Zaletel, Katja, additional, Stoinov, Julian, additional, Bucknor, Matthew, additional, Rieke, Viola, additional, Shim, Jenny, additional, Koral, Korgun, additional, Lang, Brian, additional, Wong, Carlos, additional, Lam, Heather, additional, Shinkov, Alexander, additional, Hu, Jim, additional, Zhang, Xi, additional, Macoskey, Jonathan, additional, Ives, Kimberly, additional, Owens, Gabe, additional, Gurm, Hitinder, additional, Shi, Jiaqi, additional, Pizzuto, Matthew, additional, Dillon, Christopher, additional, Christofferson, Ivy, additional, Hilas, Elaine, additional, Shea, Jill, additional, Greillier, Paul, additional, Ankou, Bénédicte, additional, Bessière, Francis, additional, Zorgani, Ali, additional, Pioche, Mathieu, additional, Kwiecinski, Wojciech, additional, Magat, Julie, additional, Melot-Dusseau, Sandrine, additional, Lacoste, Romain, additional, Quesson, Bruno, additional, Pernot, Mathieu, additional, Catheline, Stefan, additional, Chevalier, Philippe, additional, Marquet, Fabrice, additional, Bour, Pierre, additional, Vaillant, Fanny, additional, Amraoui, Sana, additional, Dubois, Rémi, additional, Ritter, Philippe, additional, Haïssaguerre, Michel, additional, Hocini, Mélèze, additional, Bernus, Olivier, additional, Tebebi, Pamela, additional, Burks, Scott, additional, Milo, Blerta, additional, Gertner, Michael, additional, Zhang, Jimin, additional, Wong, Andrew, additional, Liu, Yu, additional, Kheirolomoom, Azadeh, additional, Seo, Jai, additional, Watson, Katherine, additional, Zhang, Hua, additional, Foiret, Josquin, additional, Borowsky, Alexander, additional, Xu, Doudou, additional, Thanou, Maya, additional, Centelles, Miguell, additional, Wright, Mike, additional, Amrahli, Maral, additional, So, Po-Wah, additional, Gedroyc, Wladyslaw, additional, Kneepkens, Esther, additional, Heijman, Edwin, additional, Keupp, Jochen, additional, Weiss, Steffen, additional, Nicolay, Klaas, additional, Grüll, Holger, additional, Nagle, Matthew, additional, Nikolaeva, Anastasia V., additional, Terzi, Marina E., additional, Tsysar, Sergey A., additional, Cunitz, Bryan, additional, Mourad, Pierre, additional, Downs, Matthew, additional, Yang, Georgiana, additional, Wang, Qi, additional, Chen, Johnny, additional, Farry, Justin, additional, Dixon, Adam, additional, Du, Zhongmin, additional, Dhanaliwala, Ali, additional, Hossack, John, additional, Ranjan, Ashish, additional, Maples, Danny, additional, Wardlow, Rachel, additional, Malayer, Jerry, additional, Ramachandran, Akhilesh, additional, Namba, Hirofumi, additional, Kawasaki, Motohiro, additional, Izumi, Masashi, additional, Kiyasu, Katsuhito, additional, Takemasa, Ryuichi, additional, Ikeuchi, Masahiko, additional, Ushida, Takahiro, additional, Crake, Calum, additional, Kothapalli, Satya V. V. N., additional, Leighton, Wan, additional, Wang, Zhaorui, additional, Gach, H. Michael, additional, Straube, William, additional, Altman, Michael, additional, Kim, Young-sun, additional, Lim, Hyo Keun, additional, Rhim, Hyunchul, additional, van Breugel, Johanna, additional, Braat, Manon, additional, Moonen, Chrit, additional, van den Bosch, Maurice, additional, Ries, Mario, additional, Marrocchio, Cristina, additional, Dababou, Susan, additional, Lee, Jae Young, additional, Chung, Hyun Hoon, additional, Kang, Soo Yeon, additional, Kang, Kook Jin, additional, Son, Keon Ho, additional, Zhang, Dandan, additional, Plata, Juan, additional, Jones, Peter, additional, Pascal-Tenorio, Aurea, additional, Bouley, Donna, additional, Bond, Aaron, additional, Dallapiazza, Robert, additional, Huss, Diane, additional, Warren, Amy, additional, Sperling, Scott, additional, Gwinn, Ryder, additional, Shah, Binit, additional, Elias, W. Jeff, additional, Curley, Colleen, additional, Zhang, Ying, additional, Negron, Karina, additional, Abounader, Roger, additional, Samiotaki, Gesthimani, additional, Tu, Tsang-Wei, additional, Papadakis, Georgios, additional, Hammoud, Dima, additional, Silvestrini, Matthew, additional, Wolfram, Frank, additional, Güllmar, Daniel, additional, Reichenbach, Juergen, additional, Hofmann, Denis, additional, Böttcher, Joachim, additional, Schubert, Harald, additional, Lesser, Thomas G., additional, Almquist, Scott, additional, Camarena, Francisco, additional, Jiménez-Gambín, Sergio, additional, Jiménez, Noé, additional, Chang, Jin Woo, additional, Chaplin, Vandiver, additional, Griesenauer, Rebekah, additional, Miga, Michael, additional, Ellens, Nicholas, additional, Airan, Raag, additional, Quinones-Hinojosa, Alfredo, additional, Farahani, Keyvan, additional, Feng, Xue, additional, Fielden, Samuel, additional, Zhao, Li, additional, Wintermark, Max, additional, Meyer, Craig, additional, Guo, Sijia, additional, Lu, Xin, additional, Zhuo, Jiachen, additional, Xu, Su, additional, Gullapalli, Rao, additional, Gandhi, Dheeraj, additional, Brokman, Omer, additional, Baek, Hongchae, additional, Kim, Hyungmin, additional, Leung, Steven, additional, Webb, Taylor, additional, Vykhodtseva, Natalia, additional, Nguyen, Thai-Son, additional, Park, Chang Kyu, additional, Park, Sang Man, additional, Jung, Na Young, additional, Kim, Min Soo, additional, Chang, Won Seok, additional, Jung, Hyun Ho, additional, Plaksin, Michael, additional, Weissler, Yoni, additional, Shoham, Shy, additional, Kimmel, Eitan, additional, Rosnitskiy, Pavel B., additional, Krupa, Steve, additional, Hazan, Eilon, additional, Naor, Omer, additional, Levy, Yoav, additional, Maimon, Noam, additional, Brosh, Inbar, additional, Kahn, Itamar, additional, Cahill, Jessica, additional, Colas, Elodie Constanciel, additional, Wydra, Adrian, additional, Maev, Roman, additional, Aly, Amirah, additional, Sesenoglu-Laird, Ozge, additional, Padegimas, Linas, additional, Cooper, Mark, additional, Waszczak, Barbara, additional, Tehrani, Seruz, additional, Slingluff, Craig, additional, Larner, James, additional, Andarawewa, Kumari, additional, Ozhinsky, Eugene, additional, Shah, Rutwik, additional, Krug, Roland, additional, Deckers, Roel, additional, Linn, Sabine, additional, Suelmann, Britt, additional, Witkamp, Arjen, additional, Vaessen, Paul, additional, van Diest, Paul, additional, Bartels, Lambertus W., additional, Bos, Clemens, additional, Borys, Nicolas, additional, Storm, Gert, additional, Van der Wall, Elsken, additional, Farr, Navid, additional, Alnazeer, Moez, additional, Katti, Prateek, additional, Wood, Bradford, additional, Farrer, Alexis, additional, Ferrer, Cyril, additional, de Senneville, Baudouin Denis, additional, van Stralen, Marijn, additional, Liu, Jingfei, additional, Leach, J. Kent, additional, Zidowitz, Stephan, additional, Lee, Hsin-Lun, additional, Hsu, Fang-Chi, additional, Kuo, Chia-Chun, additional, Jeng, Shiu-Chen, additional, Chen, Tung-Ho, additional, Yang, Nai-Yi, additional, Chiou, Jeng-Fong, additional, Kao, Yi-tzu, additional, Pan, Chia-Hsin, additional, Wu, Jing-Fu, additional, Tsai, Yi-Chieh, additional, Johnson, Sara, additional, Li, Dawei, additional, He, Ye, additional, Karakitsios, Ioannis, additional, Schwenke, Michael, additional, Demedts, Daniel, additional, Xiao, Xu, additional, Cavin, Ian, additional, Minalga, Emilee, additional, Merrill, Robb, additional, Hadley, Rock, additional, Ramaekers, Pascal, additional, de Greef, Martijn, additional, Shahriari, Kian, additional, Parvizi, Mohammad Hossein, additional, Asadnia, Kiana, additional, Chamanara, Marzieh, additional, Kamrava, Seyed Kamran, additional, Chabok, Hamid Reza, additional, Stein, Ruben, additional, Muller, Sébastien, additional, Tan, Jeremy, additional, Zachiu, Cornel, additional, Erasmus, Hans-Peter, additional, Van Arsdell, Glen, additional, Benson, Lee, additional, Jang, Kee W., additional, Angstadt, Mary, additional, Lewis, Bobbi, additional, McLean, Hailey, additional, Hoogenboom, Martijn, additional, Eikelenboom, Dylan, additional, den Brok, Martijn, additional, Wesseling, Pieter, additional, Heerschap, Arend, additional, Fütterer, Jurgen, additional, Adema, Gosse, additional, Wang, Kevin, additional, Zhong, Pei, additional, Joy, Joyce, additional, McLeod, Helen, additional, Kim, Harry, additional, Lewis, Matthew, additional, Ozilgen, Arda, additional, Zahos, Peter, additional, Coughlin, Dezba, additional, Tang, Xinyan, additional, Lotz, Jeff, additional, Jedruszczuk, Kathleen, additional, Gulati, Amitabh, additional, Solomon, Stephen, additional, Kaye, Elena, additional, Mugler, John, additional, Barbato, Gaetano, additional, Scoarughi, Gian Luca, additional, Corso, Cristiano, additional, Gorgone, Alessandro, additional, Migliore, Ilaria Giuseppina, additional, Larrabee, Zachary, additional, Hananel, Arik, additional, Aubry, Jean-Francois, additional, Negussie, Ayele, additional, Wilson, Emmanuel, additional, Seifabadi, Reza, additional, Moon, Hyungwon, additional, Kang, Jeeun, additional, Sim, Changbeom, additional, Chang, Jin Ho, additional, Kim, Hyuncheol, additional, Lee, Hak Jong, additional, Sasaki, Noboru, additional, Takiguchi, Mitsuyoshi, additional, Sebeke, Lukas, additional, Luo, Xi, additional, de Jager, Bram, additional, Heemels, Maurice, additional, Abraham, Christopher, additional, Curiel, Laura, additional, Berriet, Rémi, additional, Janát-Amsbury, Margit, additional, Corea, Joseph, additional, Ye, Patrick Peiyong, additional, Arias, Ana Clauda, additional, Lustig, Micheal, additional, and Svedin, Bryant, additional

Published
2016
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15. International Society for Therapeutic Ultrasound Conference 2016: Tel Aviv, Israel. 14-18 March, 2016

Author

Fowlkes, Brian, Ghanouni, Pejman, Sanghvi, Narendra, Coussios, Constantin, Lyon, Paul C., Gray, Michael, Mannaris, Christophoros, Victor, Marie de Saint, Stride, Eleanor, Cleveland, Robin, Carlisle, Robert, Wu, Feng, Middleton, Mark, Gleeson, Fergus, Aubry, Jean-Franҫois, Pauly, Kim Butts, Moonen, Chrit, Vortman, Jacob, Sharabi, Shirley, Daniels, Dianne, Last, David, Guez, David, Levy, Yoav, Volovick, Alexander, Grinfeld, Javier, Rachmilevich, Itay, Amar, Talia, Zibly, Zion, Mardor, Yael, Harnof, Sagi, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Naor, Omer, Farah, Nairouz, Paeng, Dong-Guk, Xu, Zhiyuan, Snell, John, Quigg, Anders H., Eames, Matthew, Jin, Changzhu, Everstine, Ashli C., Sheehan, Jason P., Lopes, Beatriz S., Kassell, Neal, Looi, Thomas, Khokhlova, Vera, Mougenot, Charles, Hynynen, Kullervo, Drake, James, Slayton, Michael, Amodei, Richard C., Compton, Keegan, McNelly, Ashley, Latt, Daniel, Kearney, John, Melodelima, David, Dupre, Aurelien, Chen, Yao, Perol, David, Vincenot, Jeremy, Chapelon, Jean-Yves, Rivoire, Michel, Guo, Wei, Ren, Guoxin, Shen, Guofeng, Neidrauer, Michael, Zubkov, Leonid, Weingarten, Michael S., Margolis, David J., Lewin, Peter A., McDannold, Nathan, Sutton, Jonathan, Vykhodtseva, Natalia, Livingstone, Margaret, Kobus, Thiele, Zhang, Yong-Zhi, Schwartz, Michael, Huang, Yuexi, Lipsman, Nir, Jain, Jennifer, Chapman, Martin, Sankar, Tejas, Lozano, Andres, Yeung, Robert, Damianou, Christakis, Papadopoulos, Nikolaos, Brokman, Omer, Zadicario, Eyal, Brenner, Ori, Castel, David, Wu, Shih-Ying, Grondin, Julien, Zheng, Wenlan, Heidmann, Marc, Karakatsani, Maria Eleni, Sánchez, Carlos J. Sierra, Ferrera, Vincent, Konofagou, Elisa E., Yiannakou, Marinos, Cho, HongSeok, Lee, Hwayoun, Han, Mun, Choi, Jong-Ryul, Lee, Taekwan, Ahn, Sanghyun, Chang, Yongmin, Park, Juyoung, Ellens, Nicholas, Partanen, Ari, Farahani, Keyvan, Airan, Raag, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Lafon, Cyril, Delattre, Jean-yves, Idbaih, Ahmed, Odéen, Henrik, Bolster, Bradley, Jeong, Eun Kee, Parker, Dennis L., Gaur, Pooja, Feng, Xue, Fielden, Samuel, Meyer, Craig, Werner, Beat, Grissom, William, Marx, Michael, Weber, Hans, Taviani, Valentina, Hargreaves, Brian, Tanaka, Jun, Kikuchi, Kentaro, Ishijima, Ayumu, Azuma, Takashi, Minamihata, Kosuke, Yamaguchi, Satoshi, Nagamune, Teruyuki, Sakuma, Ichiro, Takagi, Shu, Santin, Mathieu D., Marsac, Laurent, Maimbourg, Guillaume, Monfort, Morgane, Larrat, Benoit, François, Chantal, Lehéricy, Stéphane, Tanter, Mickael, Samiotaki, Gesthimani, Wang, Shutao, Acosta, Camilo, Feinberg, Eliza R., Kovacs, Zsofia I., Tu, Tsang-Wei, Papadakis, Georgios Z., Reid, William C., Hammoud, Dima A., Frank, Joseph A., Kovacs, Zsofia i., Kim, Saejeong, Jikaria, Neekita, Bresler, Michele, Qureshi, Farhan, Xia, Jingjing, Tsui, Po-Shiang, Liu, Hao-Li, Plata, Juan C., Sveinsson, Bragi, Salgaonkar, Vasant A., Adams, Matthew, Diederich, Chris, Ozhinsky, Eugene, Bucknor, Matthew D., Rieke, Viola, Mikhail, Andrew, Severance, Lauren, Negussie, Ayele H., Wood, Bradford, de Greef, Martijn, Schubert, Gerald, Ries, Mario, Poorman, Megan E., Dockery, Mary, Chaplin, Vandiver, Dudzinski, Stephanie O., Spears, Ryan, Caskey, Charles, Giorgio, Todd, Costa, Marcia M., Papaevangelou, Efthymia, Shah, Anant, Rivens, Ian, Box, Carol, Bamber, Jeff, ter Haar, Gail, Burks, Scott R., Nagle, Matthew, Nguyen, Ben, Milo, Blerta, Le, Nhan M., Song, Shaozhen, Zhou, Kanheng, Nabi, Ghulam, Huang, Zhihong, Ben-Ezra, Shmuel, Rosen, Shani, Mihcin, Senay, Strehlow, Jan, Karakitsios, Ioannis, Le, Nhan, Schwenke, Michael, Demedts, Daniel, Prentice, Paul, Haase, Sabrina, Preusser, Tobias, Melzer, Andreas, Mestas, Jean-Louis, Chettab, Kamel, Gomez, Gustavo Stadthagen, Dumontet, Charles, Werle, Bettina, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Quesson, Bruno, Livneh, Amit, Adam, Dan, Robin, Justine, Arnal, Bastien, Fink, Mathias, Pernot, Mathieu, Khokhlova, Tatiana D., Schade, George R., Wang, Yak-Nam, Kreider, Wayne, Simon, Julianna, Starr, Frank, Karzova, Maria, Maxwell, Adam, Bailey, Michael R., Lundt, Jonathan E., Allen, Steven P., Sukovich, Jonathan R., Hall, Timothy, Xu, Zhen, May, Philip, Lin, Daniel W., Constans, Charlotte, Deffieux, Thomas, Aubry, Jean-Francois, Park, Eun-Joo, Ahn, Yun Deok, Kang, Soo Yeon, Park, Dong-Hyuk, Lee, Jae Young, Vidal-Jove, J., Perich, E., Ruiz, A., Jaen, A., Eres, N., del Castillo, M. Alvarez, Myers, Rachel, Kwan, James, Coviello, Christian, Rowe, Cliff, Crake, Calum, Finn, Sean, Jackson, Edward, Pouliopoulos, Antonios, Li, Caiqin, Tinguely, Marc, Tang, Meng-Xing, Garbin, Valeria, Choi, James J., Folkes, Lisa, Stratford, Michael, Nwokeoha, Sandra, Li, Tong, Farr, Navid, D’Andrea, Samantha, Gravelle, Kayla, Chen, Hong, Lee, Donghoon, Hwang, Joo Ha, Tardoski, Sophie, Ngo, Jacqueline, Gineyts, Evelyne, Roux, Jean-Pau, Clézardin, Philippe, Conti, Allegra, Magnin, Rémi, Gerstenmayer, Matthieu, Lux, François, Tillement, Olivier, Mériaux, Sébastien, Penna, Stefania Della, Romani, Gian Luca, Dumont, Erik, Sun, Tao, Power, Chanikarn, Miller, Eric, Sapozhnikov, Oleg, Tsysar, Sergey, Yuldashev, Petr V., Svet, Victor, Li, Dongli, Pellegrino, Antonio, Petrinic, Nik, Siviour, Clive, Jerusalem, Antoine, Yuldashev, Peter V., Cunitz, Bryan W., Dunmire, Barbrina, Inserra, Claude, Guedra, Matthieu, Mauger, Cyril, Gilles, Bruno, Solovchuk, Maxim, Sheu, Tony W. H., Thiriet, Marc, Zhou, Yufeng, Neufeld, Esra, Baumgartner, Christian, Payne, Davnah, Kyriakou, Adamos, Kuster, Niels, Xiao, Xu, McLeod, Helen, Dillon, Christopher, Payne, Allison, Khokhova, Vera A., Sinilshchikov, Ilya, Andriyakhina, Yulia, Rybyanets, Andrey, Shvetsova, Natalia, Berkovich, Alex, Shvetsov, Igor, Shaw, Caroline J., Civale, John, Giussani, Dino, Lees, Christoph, Ozenne, Valery, Toupin, Solenn, Salgaonkar, Vasant, Kaye, Elena, Monette, Sebastien, Maybody, Majid, Srimathveeravalli, Govindarajan, Solomon, Stephen, Gulati, Amitabh, Bezzi, Mario, Jenne, Jürgen W., Lango, Thomas, Müller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Günther, Matthias, Dinh, Au Hoang, Niaf, Emilie, Bratan, Flavie, Guillen, Nicolas, Souchon, Rémi, Lartizien, Carole, Crouzet, Sebastien, Rouviere, Olivier, Han, Yang, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, van Breugel, Johanna M., van den Bosch, Maurice A., Fellah, Benjamin, Le Bihan, Denis, Hernandez-Garcia, Luis, Cain, Charles A., Lyka, Erasmia, Elbes, Delphine, Li, Chunhui, Tamano, Satoshi, Jimbo, Hayato, Yoshizawa, Shin, Fujiwara, Keisuke, Itani, Kazunori, Umemura, Shin-ichiro, Stoianovici, Dan, Zaini, Zulfadhli, Takagi, Ryo, Zong, Shenyan, Watkins, Ron, Pascal-Tenorio, Aurea, Jones, Peter, Butts-Pauly, Kim, Bouley, Donna, Chen, Yazhu, Lin, Chung-Yin, Hsieh, Han-Yi, Wei, Kuo-Chen, Garnier, Camille, Renault, Gilles, Seifabadi, Reza, Wilson, Emmanuel, Eranki, Avinash, Kim, Peter, Lübke, Dennis, Huber, Peter, Georgii, Joachim, Dresky, Caroline V., Haller, Julian, Yarmolenko, Pavel, Sharma, Karun, Celik, Haydar, Li, Guofeng, Qiu, Weibao, Zheng, Hairong, Tsai, Meng-Yen, Chu, Po-Chun, Webb, Taylor, Vyas, Urvi, Walker, Matthew, Zhong, Jidan, Waspe, Adam C., Hodaie, Mojgan, Yang, Feng-Yi, Huang, Sin-Luo, Zur, Yuval, Assif, Benny, Aurup, Christian, Kamimura, Hermes, Carneiro, Antonio A., Rothlübbers, Sven, Schwaab, Julia, Houston, Graeme, Azhari, Haim, Weiss, Noam, Sosna, Jacob, Goldberg, S. Nahum, Barrere, Victor, Jang, Kee W., Lewis, Bobbi, Wang, Xiaotong, Suomi, Visa, Edwards, David, Larrabee, Zahary, Hananel, Arik, Rafaely, Boaz, Debbiny, Rasha Elaimy, Dekel, Carmel Zeltser, Assa, Michael, Menikou, George, Mouratidis, Petros, Pineda-Pardo, José A., de Pedro, Marta Del Álamo, Martinez, Raul, Hernandez, Frida, Casas, Silvia, Oliver, Carlos, Pastor, Patricia, Vela, Lidia, Obeso, Jose, Greillier, Paul, Zorgani, Ali, Catheline, Stefan, Solovov, Vyacheslav, Vozdvizhenskiy, Michael O., Orlov, Andrew E., Wu, Chueh-Hung, Sun, Ming-Kuan, Shih, Tiffany T., Chen, Wen-Shiang, Prieur, Fabrice, Pillon, Arnaud, Cartron, Valerie, Cebe, Patrick, Chansard, Nathalie, Lafond, Maxime, Seya, Pauline Muleki, Bera, Jean-Christophe, Boissenot, Tanguy, Fattal, Elias, Bordat, Alexandre, Chacun, Helene, Guetin, Claire, Tsapis, Nicolas, Maruyama, Kazuo, Unga, Johan, Suzuki, Ryo, Fant, Cécile, Rogez, Bernadette, Afadzi, Mercy, Myhre, Ola Finneng, Vea, Siri, Bjørkøy, Astrid, Yemane, Petros Tesfamichael, van Wamel, Annemieke, Berg, Sigrid, Hansen, Rune, Angelsen, Bjørn, and Davies, Catharina

Published
2017
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16. Methods and Systems for Rapid, Noninvasive Ablation of Large Tissue-Targets Using Histotripsy

Author

Lundt, Jonathan

Subjects
Histotripsy, Electronic Focal Steering, Bubble Coalescence, Breathing Motion Compensation, Focused Ultrasound Transducer Design
Abstract

Percutaneous local ablation techniques including radiofrequency and microwave ablation are increasingly supplanting surgical resection as the standard of care for solid-tumor intervention due to lower risk of complications, lower costs, and shorter associated hospital stays. However, these techniques present several risks associated with device insertion and traditionally struggle to treat tumors greater than 3 cm in diameter. Thermally-based high intensity focused ultrasound and stereotactic body radiation are noninvasive but may damage healthy surrounding tissue and require long treatment times. Thus, there is an unmet need for a noninvasive ablation technique capable of treating large tumors rapidly and safely. Histotripsy is a completely extracorporeal, non-thermal ablation technique which uses high-amplitude, short-duration, focused acoustic pulses at low duty cycle to homogenize target-tissue into an acellular slurry by means of finely-controlled acoustic cavitation. This dissertation investigated methods and systems toward the clinical translation of histotripsy for the treatment of large-volume tissue-targets. Hepatocellular carcinoma (HCC) was selected as a test-case to frame development efforts. In the first part of this dissertation, strategies for accelerating treatment based on electronic focal steering of a phased array histotripsy transducer were investigated. Research was centered around the management and manipulation of residual cavitation nuclei, hundreds of which are dispersed throughout the focus following collapse of the cavitation bubble cloud produced by each histotripsy pulse and perturb subsequent de novo cavitation at the intended focus. A novel method in which low-gain regions of the therapy beam were utilized to drive the coalescence of residual nuclei via the secondary Bjerknes force was developed and validated. Results demonstrated 99.9% complete ablation of a 27-mL volume (equivalent to a sphere 3.7 cm in diameter) within 30 s. In the second part of this dissertation, compensation methods for respiratory motion of abdominal organs during histotripsy treatment were investigated. This part of the dissertation reviewed existing methods for respiratory motion compensation, explored the feasibility of integrating these methods with histotripsy therapy, and presented a novel cavitation-based motion tracking technique. Using this technique, residual cavitation nuclei were coalesced into a small bubble-system and used as an in situ fiducial marker which was tracked throughout a predefined trajectory by a histotripsy therapy system capable of receiving acoustic backscatter signals. Results demonstrated the feasibility of receiving acoustic signals from this fiducial cavitation bubble cloud throughout a 16-cm trajectory with a mean error of 0.7 ± 0.3 mm. In the final part of the dissertation, novel design and fabrication techniques were developed for a phased array histotripsy transducer for ablation in the liver. The design implemented algorithms which analyzed human CT data to define the geometry of the array’s aperture, divided the aperture into discrete, nesting elements, and simulated the electronic focal steering range of this aperture as a function of the number of elements. The resulting design yielded an array with 50% greater packing density than previous designs. Simulation shows that this array is capable of electronically steering over a range sufficient to treat tissue-targets up to 3.6 cm in diameter in porcine or human subjects.

Published
2019

17. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, Sinai, Alon, Goldsher, Dorit, Eran, Ayelet, Nassar, Maria, Schlesinger, Ilana, Parker, Jonathon, Ravikumar, Vinod, Ghanouni, Pejman, Stein, Sherman, Halpern, Casey, Krishna, Vibhor, Hargrove, Amelia, Agrawal, Punit, Changizi, Barbara, Bourekas, Eric, Knopp, Michael, Rezai, Ali, Mead, Brian, Kim, Namho, Mastorakos, Panagiotis, Suk, Jung Soo, Miller, Wilson, Klibanov, Alexander, Hanes, Justin, Price, Richard, Wang, Shutao, Olumolade, Oluyemi, Kugelman, Tara, Jackson-Lewis, Vernice, Karakatsani, Maria Eleni (Marilena), Han, Yang, Przedborski, Serge, Konofagou, Elisa, Hynynen, Kullervo, Aubert, Isabelle, Leinenga, Gerhard, Nisbet, Rebecca, Hatch, Robert, Van der Jeugd, Anneke, Evans, Harrison, Götz, Jürgen, Van der Jeugd, Ann, Fishman, Paul, Yarowsky, Paul, Frenkel, Victor, Wei-Bin, Shen, Nguyen, Ben, Sanchez, Carlos Sierra, Acosta, Camilo, Chen, Cherry, Wu, Shih-Ying, Aryal, Muna, Papademetriou, Iason T., Zhang, Yong-Zhi, Power, Chanikarn, McDannold, Nathan, Porter, Tyrone, Kovacs, Zsofia, Kim, Saejeong, Jikaria, Neekita, Qureshi, Farhan, Bresler, Michele, Frank, Joseph, Odéen, Henrik, Chiou, George, Snell, John, Todd, Nick, Madore, Bruno, Parker, Dennis, Pauly, Kim Butts, Marx, Mike, Jonathan, Sumeeth, Grissom, William, Arvanitis, Costas, Clement, Gregory, de Bever, Joshua, Payne, Allison, Christensen, Douglas, Maimbourg, Guillaume, Santin, Mathieu David, Houdouin, Alexandre, Lehericy, Stéphane, Tanter, Mickael, Aubry, Jean Francois, Federau, Christian, Werner, Beat, Paeng, Dong-Guk, Xu, Zhiyuan, Quigg, Anders, Eames, Matt, Jin, Changzhu, Everstine, Ashli, Sheehan, Jason, Lopes, M. Beatriz, Kassell, Neal, Drake, James, Price, Karl, Lustgarten, Lior, Sin, Vivian, Mougenot, Charles, Donner, Elizabeth, Tam, Emily, Hodaie, Mojgan, Waspe, Adam, Looi, Thomas, Pichardo, Samuel, Lee, Wonhye, Chung, Yong An, Jung, Yujin, Song, In-Uk, Yoo, Seung-Schik, Kim, Hyun-Chul, Lee, Jong-Hwan, Caskey, Charles, Zinke, Wolf, Cosman, Josh, Shuman, Jillian, Schall, Jeffrey, Aurup, Christian, Chen, Hong, Kamimura, Hermes, Carneiro, Antonio, Sun, Tao, Nazai, Navid, Patz, Sam, Livingstone, Margaret, Mainprize, Todd, Huang, Yuexi, Alkins, Ryan, Chapman, Martin, Perry, James, Lipsman, Nir, Bethune, Allison, Sahgal, Arjun, Trudeau, Maureen, Liu, Hao-Li, Hsu, Po-Hung, Wei, Kuo-Chen, Sutton, Jonathan, Alexander, Phillip, Miller, Eric, Kobus, Thiele, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Beccaria, Kevin, Leclercq, Delphine, Lafon, Cyril, Chapelon, Jean Yves, Hoang-Xuan, Khe, Delattre, Jean-Yves, Idbaih, Ahmed, Moore, David, Xu, Alexis, Schmitt, Paul, Foley, Jessica, Sukovich, Jonathan, Cain, Charles, Pandey, Aditya, Chaudhary, Neeraj, Camelo-Piragua, Sandra, Allen, Steven, Cannata, Jon, Teofilovic, Dejan, Bertolina, Jim, Hall, Timothy, Xu, Zhen, Grondin, Julien, Ferrera, Vincent, ter Haar, Gail, Mouratidis, Petros, Repasky, Elizabeth, Timbie, Kelsie, Badr, Lena, Campbell, Benjamin, McMichael, John, Buckner, Andrew, Prince, Jessica, Stevens, Aaron, Bullock, Timothy, Skalina, Karin, Guha, Chandan, Orsi, Franco, Bonomo, Guido, Vigna, Paolo Della, Mauri, Giovanni, Varano, Gianluca, Schade, George, Wang, Yak-Nam, Pillarisetty, Venu, Hwang, Joo Ha, Khokhlova, Vera, Bailey, Michael, Khokhlova, Tatiana, Sinilshchikov, Ilya, Yuldashev, Petr, Andriyakhina, Yulia, Kreider, Wayne, Maxwell, Adam, Sapozhnikov, Oleg, Partanen, Ari, Lundt, Jonathan, Preusser, Tobias, Haase, Sabrina, Bezzi, Mario, Jenne, Jürgen, Langø, Thomas, Midiri, Massimo, Mueller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Guenther, Matthias, Melzer, Andreas, Menciassi, Arianna, Tognarelli, Selene, Cafarelli, Andrea, Diodato, Alessandro, Ciuti, Gastone, Rothluebbers, Sven, Schwaab, Julia, Strehlow, Jan, Mihcin, Senay, Tretbar, Steffen, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, Adams, Matthew, Salgaonkar, Vasant, Scott, Serena, Sommer, Graham, Diederich, Chris, Vidal-Jove, Joan, Perich, Eloi, Ruiz, Antonio, Velat, Manuela, Melodelima, David, Dupre, Aurelien, Vincenot, Jeremy, Yao, Chen, Perol, David, Rivoire, Michel, Tucci, Samantha, Mahakian, Lisa, Fite, Brett, Ingham, Elizabeth, Tam, Sarah, Hwang, Chang-il, Tuveson, David, Ferrara, Katherine, Scionti, Stephen, Chen, Lili, Cvetkovic, Dusica, Chen, Xiaoming, Gupta, Roohi, Wang, Bin, Ma, Charlie, Bader, Kenneth, Haworth, Kevin, Holland, Christy, Sanghvi, Narendra, Carlson, Roy, Chen, Wohsing, Chaussy, Christian, Thueroff, Stefan, Cesana, Claudio, Bellorofonte, Carlo, Wang, Qingguo, Wang, Han, Wang, Shengping, Zhang, Junhai, Bazzocchi, Alberto, Napoli, Alessandro, Staruch, Robert, Bing, Chenchen, Shaikh, Sumbul, Nofiele, Joris, Szczepanski, Debra, Staruch, Michelle Wodzak, Williams, Noelle, Laetsch, Theodore, Chopra, Rajiv, Rosenberg, Jarrett, Bitton, Rachelle, LeBlang, Suzanne, Meyer, Joshua, Hurwitz, Mark, Yarmolenko, Pavel, Celik, Haydar, Eranki, Avinash, Beskin, Viktoriya, Santos, Domiciano, Patel, Janish, Oetgen, Matthew, Kim, AeRang, Kim, Peter, Sharma, Karun, Chisholm, Alexander, Aleman, Dionne, Scipione, Roberto, Temple, Michael, Amaral, Joao Guilherme, Endre, Ruby, Lamberti-Pasculli, Maria, de Ruiter, Joost, Campbell, Fiona, Stimec, Jennifer, Gupta, Samit, Singh, Manoj, Hopyan, Sevan, Czarnota, Gregory, Brenin, David, Rochman, Carrie, Kovatcheva, Roussanka, Vlahov, Jordan, Zaletel, Katja, Stoinov, Julian, Bucknor, Matthew, Rieke, Viola, Shim, Jenny, Koral, Korgun, Lang, Brian, Wong, Carlos, Lam, Heather, Shinkov, Alexander, Hu, Jim, Zhang, Xi, Macoskey, Jonathan, Ives, Kimberly, Owens, Gabe, Gurm, Hitinder, Shi, Jiaqi, Pizzuto, Matthew, Dillon, Christopher, Christofferson, Ivy, Hilas, Elaine, Shea, Jill, Greillier, Paul, Ankou, Bénédicte, Bessière, Francis, Zorgani, Ali, Pioche, Mathieu, Kwiecinski, Wojciech, Magat, Julie, Melot-Dusseau, Sandrine, Lacoste, Romain, Quesson, Bruno, Pernot, Mathieu, Catheline, Stefan, Chevalier, Philippe, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Tebebi, Pamela, Burks, Scott, Milo, Blerta, Gertner, Michael, Zhang, Jimin, Wong, Andrew, Liu, Yu, Kheirolomoom, Azadeh, Seo, Jai, Watson, Katherine, Zhang, Hua, Foiret, Josquin, Borowsky, Alexander, Xu, Doudou, Thanou, Maya, Centelles, Miguell, Wright, Mike, Amrahli, Maral, So, Po-Wah, Gedroyc, Wladyslaw, Kneepkens, Esther, Heijman, Edwin, Keupp, Jochen, Weiss, Steffen, Nicolay, Klaas, Grüll, Holger, Nagle, Matthew, Nikolaeva, Anastasia V., Terzi, Marina E., Tsysar, Sergey A., Cunitz, Bryan, Mourad, Pierre, Downs, Matthew, Yang, Georgiana, Wang, Qi, Chen, Johnny, Farry, Justin, Dixon, Adam, Du, Zhongmin, Dhanaliwala, Ali, Hossack, John, Ranjan, Ashish, Maples, Danny, Wardlow, Rachel, Malayer, Jerry, Ramachandran, Akhilesh, Namba, Hirofumi, Kawasaki, Motohiro, Izumi, Masashi, Kiyasu, Katsuhito, Takemasa, Ryuichi, Ikeuchi, Masahiko, Ushida, Takahiro, Crake, Calum, Kothapalli, Satya V. V. N., Leighton, Wan, Wang, Zhaorui, Gach, H. Michael, Straube, William, Altman, Michael, Kim, Young-sun, Lim, Hyo Keun, Rhim, Hyunchul, van Breugel, Johanna, Braat, Manon, Moonen, Chrit, van den Bosch, Maurice, Ries, Mario, Marrocchio, Cristina, Dababou, Susan, Lee, Jae Young, Chung, Hyun Hoon, Kang, Soo Yeon, Kang, Kook Jin, Son, Keon Ho, Zhang, Dandan, Plata, Juan, Jones, Peter, Pascal-Tenorio, Aurea, Bouley, Donna, Bond, Aaron, Dallapiazza, Robert, Huss, Diane, Warren, Amy, Sperling, Scott, Gwinn, Ryder, Shah, Binit, Elias, W. Jeff, Curley, Colleen, Zhang, Ying, Negron, Karina, Abounader, Roger, Samiotaki, Gesthimani, Tu, Tsang-Wei, Papadakis, Georgios, Hammoud, Dima, Silvestrini, Matthew, Wolfram, Frank, Güllmar, Daniel, Reichenbach, Juergen, Hofmann, Denis, Böttcher, Joachim, Schubert, Harald, Lesser, Thomas G., Almquist, Scott, Camarena, Francisco, Jiménez-Gambín, Sergio, Jiménez, Noé, Chang, Jin Woo, Chaplin, Vandiver, Griesenauer, Rebekah, Miga, Michael, Ellens, Nicholas, Airan, Raag, Quinones-Hinojosa, Alfredo, Farahani, Keyvan, Feng, Xue, Fielden, Samuel, Zhao, Li, Wintermark, Max, Meyer, Craig, Guo, Sijia, Lu, Xin, Zhuo, Jiachen, Xu, Su, Gullapalli, Rao, Gandhi, Dheeraj, Brokman, Omer, Baek, Hongchae, Kim, Hyungmin, Leung, Steven, Webb, Taylor, Vykhodtseva, Natalia, Nguyen, Thai-Son, Park, Chang Kyu, Park, Sang Man, Jung, Na Young, Kim, Min Soo, Chang, Won Seok, Jung, Hyun Ho, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Rosnitskiy, Pavel B., Krupa, Steve, Hazan, Eilon, Naor, Omer, Levy, Yoav, Maimon, Noam, Brosh, Inbar, Kahn, Itamar, Cahill, Jessica, Colas, Elodie Constanciel, Wydra, Adrian, Maev, Roman, Aly, Amirah, Sesenoglu-Laird, Ozge, Padegimas, Linas, Cooper, Mark, Waszczak, Barbara, Tehrani, Seruz, Slingluff, Craig, Larner, James, Andarawewa, Kumari, Ozhinsky, Eugene, Shah, Rutwik, Krug, Roland, Deckers, Roel, Linn, Sabine, Suelmann, Britt, Witkamp, Arjen, Vaessen, Paul, van Diest, Paul, Bartels, Lambertus W., Bos, Clemens, Borys, Nicolas, Storm, Gert, Van der Wall, Elsken, Farr, Navid, Alnazeer, Moez, Katti, Prateek, Wood, Bradford, Farrer, Alexis, Ferrer, Cyril, de Senneville, Baudouin Denis, van Stralen, Marijn, Liu, Jingfei, Leach, J. Kent, Zidowitz, Stephan, Lee, Hsin-Lun, Hsu, Fang-Chi, Kuo, Chia-Chun, Jeng, Shiu-Chen, Chen, Tung-Ho, Yang, Nai-Yi, Chiou, Jeng-Fong, Kao, Yi-tzu, Pan, Chia-Hsin, Wu, Jing-Fu, Tsai, Yi-Chieh, Johnson, Sara, Li, Dawei, He, Ye, Karakitsios, Ioannis, Schwenke, Michael, Demedts, Daniel, Xiao, Xu, Cavin, Ian, Minalga, Emilee, Merrill, Robb, Hadley, Rock, Ramaekers, Pascal, de Greef, Martijn, Shahriari, Kian, Parvizi, Mohammad Hossein, Asadnia, Kiana, Chamanara, Marzieh, Kamrava, Seyed Kamran, Chabok, Hamid Reza, Stein, Ruben, Muller, Sébastien, Tan, Jeremy, Zachiu, Cornel, Erasmus, Hans-Peter, Van Arsdell, Glen, Benson, Lee, Jang, Kee W., Angstadt, Mary, Lewis, Bobbi, McLean, Hailey, Hoogenboom, Martijn, Eikelenboom, Dylan, den Brok, Martijn, Wesseling, Pieter, Heerschap, Arend, Fütterer, Jurgen, Adema, Gosse, Wang, Kevin, Zhong, Pei, Joy, Joyce, McLeod, Helen, Kim, Harry, Lewis, Matthew, Ozilgen, Arda, Zahos, Peter, Coughlin, Dezba, Tang, Xinyan, Lotz, Jeff, Jedruszczuk, Kathleen, Gulati, Amitabh, Solomon, Stephen, Kaye, Elena, Mugler, John, Barbato, Gaetano, Scoarughi, Gian Luca, Corso, Cristiano, Gorgone, Alessandro, Migliore, Ilaria Giuseppina, Larrabee, Zachary, Hananel, Arik, Aubry, Jean-Francois, Negussie, Ayele, Wilson, Emmanuel, Seifabadi, Reza, Moon, Hyungwon, Kang, Jeeun, Sim, Changbeom, Chang, Jin Ho, Kim, Hyuncheol, Lee, Hak Jong, Sasaki, Noboru, Takiguchi, Mitsuyoshi, Sebeke, Lukas, Luo, Xi, de Jager, Bram, Heemels, Maurice, Abraham, Christopher, Curiel, Laura, Berriet, Rémi, Janát-Amsbury, Margit, Corea, Joseph, Ye, Patrick Peiyong, Arias, Ana Clauda, Lustig, Micheal, and Svedin, Bryant

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, Fibroadenomata, Cryo-ablation, High-intensity focused ultrasound, Ablative techniques, lcsh:R895-920, Review, Meeting Abstracts, Laser ablation
Abstract

Introduction Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomatic. For symptomatic patients, the lumps can be surgically excised or removed interventionally by vacuum-assisted mammotomy (VAM). Ablative techniques like high-intensity focused ultrasound (HIFU), cryo-ablation and laser ablation have also been used for the treatment of FAD, providing a minimally invasive treatment without scarring or poor cosmesis. This review summarises current trials using minimally invasive ablative techniques in the treatment of breast FAD. Methods A comprehensive review of studies using minimally invasive ablative techniques was performed. Results There are currently several trials completed or recruiting patients using HIFU, cryo-ablation and laser ablation in the treatment of breast FAD. The results look very promising but cannot be compared at this point due to heterogeneity between studies. Conclusion Minimally invasive ablative techniques like HIFU, cryo-ablation and laser ablation are promising in the treatment of breast FAD. Future trials should be randomised and contain larger numbers of patients to determine the effectiveness of ablative techniques with more precision.

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18. Histotripsy for Non-Invasive Ablation of Hepatocellular Carcinoma (HCC) Tumor in a Subcutaneous Xenograft Murine Model.

Author

Worlikar T, Vlaisavljevich E, Gerhardson T, Greve J, Wan S, Kuruvilla S, Lundt J, Ives K, Hall T, Welling TH, Lee F, and Xu Z

Subjects
Animals, Disease Models, Animal, Heterografts, High-Intensity Focused Ultrasound Ablation, Humans, Mice, Mice, Inbred NOD, Mice, SCID, Carcinoma, Hepatocellular, Liver Neoplasms
Abstract

Histotripsy fractionates tissue through a mechanical, non-invasive ultrasonic ablation process that precisely controls acoustic cavitation while utilizing real-time ultrasound (US) imaging guidance. This study investigates the potential, feasibility and tumor volume reduction effects of histotripsy for liver cancer ablation in a subcutaneous in vivo murine Hepatocellular Carcinoma (HCC) model. Hep3B tumors were generated in the right flanks of 14 NSG and 7 NOD-SCID mice. The mice were grouped as follows: A (acute, NSG with n=9 treatment and n=1 control), B (chronic, NSG with n=2 treatment and n=2 control) and C (chronic NODSCID, with n=6 treatment and n=1 control). Treatment was performed when the tumor diameters reached >5 mm. 1-2 cycle histotripsy pulses at 100 Hz PRF (p- >30 MPa) were delivered using a custom built 1 MHz therapy transducer attached to a motorized positioner, which scanned the transducer focus to traverse the targeted tumor volume, guided by real-time US imaging. Tumor ablation effectiveness was assessed by obtaining T1, T2 and T2* weighted MR images. Post euthanasia, treated tumor, brain, and lung tissue samples were harvested for histology. Histology of acute group A showed fractionation of targeted region with a sharp boundary separating it from untreated tissue. Groups B and C demonstrated effective tumor volume reduction post treatment on MRI as the homogenate and edema were resorbed within 23 weeks. However, as the tumor was subcutaneous, it was not possible to set adequate treatment margin and since the mice were immune-compromised, residual viable tumor cells eventually developed into tumor regrowth at 3-9 weeks after histotripsy. Groups B and C showed no signs of metastasis in the lung and brain. Our study successfully demonstrated the potential of histotripsy for non-invasive HCC ablation in a subcutaneous murine model. Additional work is ongoing to study the response of histotripsy in immune-competent orthotopic liver tumor models.

Published
2018
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