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Your search keyword '"Luo, Fei‐Xian"' showing total 30 results
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30 results on '"Luo, Fei‐Xian"'

25. Synthesis of Dibenzo[c,e]oxepin-5(7 H)-ones from Benzyl Thioethers and Carboxylic Acids: Rhodium-Catalyzed Double CH Activation Controlled by Different Directing Groups.

Author

Zhang, Xi-Sha, Zhang, Yun-Fei, Li, Zhao-Wei, Luo, Fei-Xian, and Shi, Zhang-Jie

Subjects
RHODIUM, CARBOXYLIC acids, CARBON-hydrogen bonds, ORGANIC synthesis, BIOCHEMICAL substrates, CHEMICAL reagents
Abstract

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the formation of two bonds (CC, CO). The formed structure is the privileged core in natural products and bioactive molecules. This work highlights the power of using two different directing groups to enhance the selectivity of a double CH activation, the first of such examples in cross-oxidative coupling. [ABSTRACT FROM AUTHOR]

Published
2015
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27. ChemInform Abstract: Cu-Catalyzed Alkynylation of Unactivated C(sp3)-X Bonds with Terminal Alkynes Through Directing Strategy.

Author

Luo, Fei‐Xian, Xu, Xing, Wang, Ding, Cao, Zhi‐Chao, Zhang, Yun‐Fei, and Shi, Zhang‐Jie

Subjects
*ALKYL chlorides, *ALKYNES, *COPPER catalysts, *CARBON-carbon bonds, *QUINOLINE derivatives
Abstract

Following a scalable procedure alkyl chlorides equipped with a quinoline amide directing group are cross-coupled with various terminal alkynes to afford internal alkynes in high yields. [ABSTRACT FROM AUTHOR]

Published
2016
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28. Unexpected Cascade Dehydrogenation Triggered by Pd/Cu-Catalyzed C(sp 3 )-H Arylation/Intramolecular C-N Coupling of Amides: Facile Access to 1,2-Dihydroquinolines.

Author

Zheng QC, Peng SY, Cong SQ, Ning XY, Guo Y, Li MJ, Wang WS, Cui XJ, and Luo FX

Subjects
Catalysis, Molecular Structure, Amides chemistry, Palladium chemistry
Abstract

In this work, we successfully explored an unexpected dehydrogenation triggered by Pd/Cu-catalyzed C(sp 3 )-H arylation and intramolecular C-N coupling of amides to synthesize the bioactive 1,2-dihydroquinoline scaffold with good regioselectivity and good compatibility of functional groups. This strategy provides an alternative route to realize molecular complexity and diversity from simple and readily available molecules via multiple C-H bond activation. Preliminary mechanistic studies demonstrated that β,γ-dehydrogenation is triggered by the arylation of the C(sp 3 )-H bond and the intramolecular C-N coupling.

Published
2022
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29. Pd/Cu-Catalyzed Cascade C(sp 3 )-H Arylation and Intramolecular C-N Coupling: A One-Pot Synthesis of 3,4-2 H-Quinolinone Skeletons.

Author

Xiao HZ, Wang WS, Sun YS, Luo H, Li BW, Wang XD, Lin WL, and Luo FX

Abstract

In this letter, we successfully explored a cascade Pd/Cu-catalyzed intermolecular C(sp 3 )-H arylation of amides and intramolecular C-N coupling reaction. This method provides a one-pot strategy to synthesize 3,4-2 H-quinolinone with good regioselectivity of C-H arylation and C-N coupling from C-I and C-X bonds from readily available starting materials.

Published
2019
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30. Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: rhodium-catalyzed double C-H activation controlled by different directing groups.

Author

Zhang XS, Zhang YF, Li ZW, Luo FX, and Shi ZJ

Abstract

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the formation of two bonds (CC, CO). The formed structure is the privileged core in natural products and bioactive molecules. This work highlights the power of using two different directing groups to enhance the selectivity of a double CH activation, the first of such examples in cross-oxidative coupling., (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2015
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