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8 results on '"Lupande, David"'

4. Bhargavaea massiliensis sp. nov. and Dietzia massiliensis sp. nov., Novel Bacteria Species Isolated from Human Urine Samples in Nigeria

Author

Olowo-okere, Ahmed, primary, Ibrahim, Yakubu Kokori Enevene, additional, Lo, Cheikh Ibrahima, additional, Olayinka, Busayo Olalekan, additional, Yimagou, Edmond Kuete, additional, Yacouba, Abdourahamane, additional, Mohammed, Yahaya, additional, Nabti, Larbi Zakaria, additional, Ragueh, Ayan Ali, additional, Lupande, David, additional, Raoult, Didier, additional, Rolain, Jean-Marc, additional, and Diene, Seydina M., additional

Published
2021
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5. Seroprevalence and Risk Factors of the Helicobacter pylori Infection in Bukavu City in the Democratic Republic of Congo

Author

Ngoma, Patrick de Jésus, primary, Longo-Mbenza, Benjamin, additional, Tshibangu-Kabamba, Evariste, additional, Matungo, Bellarmin, additional, Lupande, David, additional, Malu, Christian, additional, Kengibe, Pitchou, additional, Yaba, Antoine Tshimpi Wola, additional, Nlombi, Charles Mbendi, additional, Fiasse, René, additional, Hafid, Dahma, additional, Kabinda, Jeff, additional, Yamaoka, Yoshio, additional, Nkodila, Aliocha, additional, and Deyi, Véronique Yvette Miendje, additional

Published
2021
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8. [Role of GeneXpert MTB/RIF test in the screening for pulmonary tuberculosis at the General Referral Provincial Hospital of Bukavu, in the East of the Democratic Republic of the Congo: balance after 10 months of use].

Author

Lupande D, Kaishusha D, Mihigo C, Itongwa M, Yenga G, and Katchunga P

Subjects
Adult, Democratic Republic of the Congo, Drug Resistance, Multiple, Bacterial, Female, HIV Seropositivity epidemiology, Humans, Male, Middle Aged, Mycobacterium tuberculosis drug effects, Retrospective Studies, Sensitivity and Specificity, Staining and Labeling methods, Tuberculosis, Pulmonary microbiology, Young Adult, Antitubercular Agents pharmacology, Molecular Diagnostic Techniques methods, Rifampin pharmacology, Tuberculosis, Pulmonary diagnosis
Abstract

Introduction: In sub-Saharan Africa, diagnostic methods for tuberculosis are inadequate and are essentially based on microscopy. They constitute a real obstacle to the control of tuberculosis. This study aimed to evaluate the performance of GeneXpert MTB/RIF test compared to classical Ziehl-Neelsen staining at the the general referral provincial hospital of Bukavu, in the east of the Democratic Republic of the Congo after 10 months of use., Methods: The results of Ziehl-Neelsen staining and GeneXpert MTB/RIF molecular biology test performed in 452 patients with suspected tuberculosis were collected. This study compares the validity of these different diagnostic tests in the detection of tuberculosis., Results: In the entire group, the frequency of the pulmonary tuberculosis was 16.3%. The positivity rate was significantly higher in GeneXpert MTB/RIF test than in Ziehl-Neelsen staining in the entire group (15.9% vs 9.3%, p = 0.03) and in HIV seropositive patients (52.0% vs 24.0%; p = 0.007). However, the sensitivity of GeneXpert MTB/RIF test compared to that in Ziehl-Neelsen staining wasn't maximum (95.2%). Finally, GeneXpert MTB/RIF test detected rifampicin resistance in 20.8%., Conclusion: This study confirms the superiority of GeneXpert MTB/RIF test compared to Ziehl-Neelsen staining in the detection of tuberculosis and in the prediction of multi-resistance. Its systematic use coupled with Ziehl-Neelsen staining would better control tuberculosis in sub-Saharan Africa.

Published
2017
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