Search

Your search keyword '"Lv, Yanfei"' showing total 155 results
Start Over Author "Lv, Yanfei"
155 results on '"Lv, Yanfei"'

11. Caspase-11-mediated enteric neuronal pyroptosis underlies Western diet-induced colonic dysmotility

Author

Ye, Lan, Li, Ge, Goebel, Anna, Raju, Abhinav V., Kong, Feng, Lv, Yanfei, Li, Kailin, Zhu, Yuanjun, Raja, Shreya, He, Peijian, Li, Fang, Mwangi, Simon Musyoka, Hu, Wenhui, and Srinivasan, Shanthi

Subjects
Obesity -- Comparative analysis, Apoptosis -- Comparative analysis, Electric fields -- Comparative analysis, Neurophysiology -- Comparative analysis, Mitogens -- Comparative analysis, Gastrointestinal diseases -- Comparative analysis, Animal experimentation -- Comparative analysis, Saturated fatty acids -- Comparative analysis, Neurons -- Comparative analysis, Diet -- Comparative analysis, Health care industry
Abstract

Enteric neuronal degeneration, as seen in inflammatory bowel disease, obesity, and diabetes, can lead to gastrointestinal dysmotility. Pyroptosis is a novel form of programmed cell death but little is known about its role in enteric neuronal degeneration. We observed higher levels of cleaved caspase-1, a marker of pyroptosis, in myenteric ganglia of overweight and obese human subjects compared with normal-weight subjects. Western diet-fed (WD-fed) mice exhibited increased myenteric neuronal pyroptosis, delayed colonic transit, and impaired electric field stimulation-induced colonic relaxation responses. WD increased TLR4 expression and cleaved caspase-1 in myenteric nitrergic neurons. Overactivation of nitrergic neuronal NF-[kappa]B signaling resulted in increased pyroptosis and delayed colonic motility. In caspase-11-deficient mice, WD did not induce nitrergic myenteric neuronal pyroptosis and colonic dysmotility. To understand the contributions of saturated fatty acids and bacterial products to the steps leading to enteric neurodegeneration, we performed in vitro experiments using mouse enteric neurons. Palmitate and lipopolysaccharide (LPS) increased nitrergic, but not cholinergic, enteric neuronal pyroptosis. LPS gained entry to the cytosol in the presence of palmitate, activating caspase-11 and gasdermin D, leading to pyroptosis. These results support a role of the caspase-11-mediated pyroptotic pathway in WD-induced myenteric nitrergic neuronal degeneration and colonic dysmotility, providing important therapeutic targets for enteric neuropathy., Introduction The Western diet (WD) is characterized by 50% carbohydrate, 15% protein, and 35% fat (1), in which the intake of fat falls in the upper limit of the 25% [...]

Published
2020
Full Text
View/download PDF

12. Augmented Self-paced Learning with Generative Adversarial Networks

Author

Zhang, Xiao-Yu, Wang, Shupeng, Lv, Yanfei, Li, Peng, Wang, Haiping, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Shi, Yong, editor, Fu, Haohuan, editor, Tian, Yingjie, editor, Krzhizhanovskaya, Valeria V., editor, Lees, Michael Harold, editor, Dongarra, Jack, editor, and Sloot, Peter M. A., editor

Published
2018
Full Text
View/download PDF

17. AAA: A Massive Data Acquisition Approach in Large-Scale System Monitoring

Author

Zhou, Runlin, Lv, Yanfei, Fan, Dongjin, Zhang, Hong, Zhu, Chunge, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Zhan, Jianfeng, editor, Han, Rui, editor, and Zicari, Roberto V., editor

Published
2016
Full Text
View/download PDF

19. Recent Developments in the Electrochemical Determination of Sulfonamides

Author

Zhang Xin-yi, Zhao Shi-chao, Chen Fei, Fu Li, Ding Su, Lv Yanfei, and Zhang Huaiwei

Subjects
Chemistry, Biophysics, Pharmaceutical Science, Molecular Medicine, Nanotechnology, Electrochemistry, Biochemistry
Abstract

Background: Sulfonamides are the anti-bacterial and anti-inflammatory drugs synthesized, which are widely used as medical and veterinary antibiotics. However, the excess dosage of sulfonamides can harm human health. Drug residues in animal products also can harm human health through the food chain. The long-term consumption of animal food containing drug residues will cause some toxicity and side effects on human body functions, which will seriously threaten human health. Methods: Electroanalytical methods are attracting much attention because of their advantage over conventional methods, as they are quick, low-cost, high sensitivity, and portable. This review examines the progress made in the selective electrochemical determination of sulfonamides in the last 20 years. Results: In this review, we describe the development of electrochemical methods for sulfonamides determination. Then, we pay special attention to the detection of sulfonamides using molecular imprinting technology. The linear detection range with the limit of detection has been listed for comparison. Conclusion: Electrochemical determination of sulfonamides is a fast, simple, sensitive, and cost-effective approach. The surface modification of commercial electrodes can significantly improve the sensing performance.

Published
2022

22. bCATE: A Balanced Contention-Aware Transaction Execution Model for Highly Concurrent OLTP Systems

Author

Shi, Xiaogang, Lv, Yanfei, Shao, Yingxia, Cui, Bin, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Wang, Jianyong, editor, Xiong, Hui, editor, Ishikawa, Yoshiharu, editor, Xu, Jianliang, editor, and Zhou, Junfeng, editor

Published
2013
Full Text
View/download PDF

23. A Probabilistic Data Replacement Strategy for Flash-Based Hybrid Storage System

Author

Lv, Yanfei, Chen, Xuexuan, Sun, Guangyu, Cui, Bin, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ishikawa, Yoshiharu, editor, Li, Jianzhong, editor, Wang, Wei, editor, Zhang, Rui, editor, and Zhang, Wenjie, editor

Published
2013
Full Text
View/download PDF

24. Log-Compact R-Tree: An Efficient Spatial Index for SSD

Author

Lv, Yanfei, Li, Jing, Cui, Bin, Chen, Xuexuan, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Xu, Jianliang, editor, Yu, Ge, editor, Zhou, Shuigeng, editor, and Unland, Rainer, editor

Published
2011
Full Text
View/download PDF

25. ACAR: An Adaptive Cost Aware Cache Replacement Approach for Flash Memory

Author

Lv, Yanfei, Chen, Xuexuan, Cui, Bin, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Chen, Lei, editor, Tang, Changjie, editor, Yang, Jun, editor, and Gao, Yunjun, editor

Published
2010
Full Text
View/download PDF

26. A Simple But Effective Event-Driven Model for Data Stream Queries

Author

Gu, Yu, Yu, Ge, Wu, Shanshan, Li, Xiaojing, Lv, Yanfei, Yue, Dejun, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Rangan, C. Pandu, editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Dong, Guozhu, editor, Lin, Xuemin, editor, Wang, Wei, editor, Yang, Yun, editor, and Yu, Jeffrey Xu, editor

Published
2007
Full Text
View/download PDF

27. A QoS-Guaranteeing Scheduling Algorithm for Continuous Queries over Streams

Author

Wu, Shanshan, Lv, Yanfei, Yu, Ge, Gu, Yu, Li, Xiaojing, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Rangan, C. Pandu, editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Dong, Guozhu, editor, Lin, Xuemin, editor, Wang, Wei, editor, Yang, Yun, editor, and Yu, Jeffrey Xu, editor

Published
2007
Full Text
View/download PDF

28. Modelling and Guaranteeing Quality of Service over Data Streams

Author

Wu, Shanshan, Gu, Yu, Lv, Yanfei, Yu, Ge, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Feng, Ling, editor, Wang, Guoren, editor, Zeng, Cheng, editor, and Huang, Ruhua, editor

Published
2006
Full Text
View/download PDF

37. Efficacy and safety of bloodletting for herpes zoster

Author

Wang, Xiaoyan, Huang, Shaolei, Shao, Guoliang, Zhang, Jian, Wang, Suyao, Lv, Yanfei, Dong, Feng, Han, Jing, and Yang, Dianhui

Subjects
Male, Herpesvirus 3, Human, bloodletting, herpes zoster, Herpes Zoster, Treatment Outcome, herpesvirus, systematic review, Study Protocol Systematic Review, Humans, Female, protocol, Medicine, Chinese Traditional, Safety, Research Article, Bloodletting, Data Management, Randomized Controlled Trials as Topic
Abstract

Background: The study aims to evaluate the effectiveness and safety of bloodletting therapy for herpes zoster. Methods: The following electronic databases will be searched from PubMed (1966 to March 2020), the Cochrane Central Register of Controlled Trials (update to March 2020), EMBASE (1980 to March 2020), China National Knowledge Infrastructure (1979 to March 2020), Wan Fang Data (1980 to March 2020), Chinese Scientific Journal Database (1989 to March 2020), Chinese Biomedical Database (1978 to March 2020) and traditional Chinese medicine Literature Analysis and Retrieval Database (1949 to March 2020). All randomized controlled trials without any limitation of blinding or publication language about this topic will be included, exclude cohort studies and case reports. Two independent researchers will operate article retrieval, duplication removing, screening, quality evaluation, and data analyses by Review Manager (V.5.3.5). Meta-analyses, subgroup analysis, and/or descriptive analysis will be performed based on the included data conditions. Results: High-quality synthesis and/or descriptive analysis of current evidence will be provided from cure rate, converting to clinical diagnosis rate, and side effects of bloodletting. Conclusion: This study will provide the evidence of whether bloodletting is an effective and safe intervention for herpes zoster. PROSPERO registration number: CRD42020171976

Published
2021

39. Preparation and Near‐Infrared Photoelectric Properties of n‐Type Cu3P.

Author

Peng, Xue, Lv, Yanfei, Xi, Junhua, Fu, Li, Chen, Fei, Su, Weitao, Li, Jingzhou, and Zhao, Shichao

Subjects
*X-ray emission spectroscopy, *LASER spectroscopy, *FIELD emission electron microscopy, *ELECTRONIC equipment, *RAMAN spectroscopy, *X-ray spectroscopy
Abstract

As intrinsic cuprous phosphide (Cu3P) shows p‐type conductivity, the investigation of n‐type Cu3P (n‐Cu3P) was lacking and hindered its development and application. In this paper, novel n‐type conducting cuprous phosphide (n‐Cu3P) has been prepared by annealing ZnO/Cu3P/Cu structure. The morphology, composition and structure of the thin films were characterized by field emission scanning electron microscopy (FSEM), energy dispersive X‐ray spectrometer (EDX), X‐ray diffraction spectroscopy (XRD) and laser Raman spectroscopy (Raman). The semiconductor conduction type was analyzed by thermal probe method and Hall coefficient method. The transition of conduction type from p‐type to n‐type occurred as ZnO/Cu3P/Cu was annealed at 550 °C. The growth mechanism of n‐Cu3P was discussed. Finally, the infrared absorption and photoelectric properties were investigated. The near‐infrared photoelectronic performance of Cu3P was reported for the first time. The successful preparation of n‐Cu3P is helpful to promote the research and application of Cu3P based electronic devices. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

41. Feature extraction method of football fouls based on deep learning algorithm

Author

Ma, Weicheng and Lv, Yanfei

Abstract

In order to overcome the problems of abnormal detection and low accuracy in the process of football foul feature extraction, this paper proposes a football foul feature extraction method based on deep learning algorithm to accurately identify the fouls in the process of normal competition. In this method, the background is eliminated by the difference between the input image and the background image, so as to obtain the effective detection target. According to the characteristics of football competition, the human motion tracking algorithm is proposed. Through the template representation, candidate target representation, similarity measurement calculation and search strategy, the dynamic target is tracked in real-time, and its dynamic information is obtained. Finally, the star skeleton feature is used to extract the football foul action feature, and the image feature is transformed into available data to realise the data extraction of action feature. The experimental results show that the proposed method can detect the target with low accuracy.

Published
2023
Full Text
View/download PDF

48. Protective effect of Pulsatilla saponin A on acute myocardial infarction via miR-24-3p/p16.

Author

Dong, Feng, Pu, Yanhua, Lv, Yanfei, Liu, Xiujuan, and Cao, Yimin

Subjects
CELL cycle, WESTERN immunoblotting
Abstract

The effect of Pulsatilla saponin A (PsA) on acute myocardial infarction (AMI) was unknown. This study targeted to examine the roles of PsA on hypoxia-triggered toxicity to H9c2 cells and reveal the potential mechanism. H9c2 cells were maintained under a hypoxic environment for 12 h to construct the AMI cell model and the cells were pretreated by PsA. Hypoxia triggered toxicity to H9c2 cells and the anti-toxicity effect of PsA was evaluated by CCK8, TUNEL, and Western blot. The levels of miR-24-3p and p16 in H9c2 cells, AMI group tissues, and their respective controls were assessed using qRT-PCR. The dual-luciferase assay was applied to verify the targeting mechanism of miR-24-3p on p16. Then the effects of miR-24-3p inhibitor or/and si-p16 on H9c2 cells treated with PsA under hypoxia were detected by CCK8, TUNEL, and Western blot. Flow cytometry was executed to determine the cell cycle. Hypoxia decreased viability and proliferation and increased apoptosis of H9c2 cells, which were ameliorated by PsA pretreatment. The level of miR-24-3p was diminished, but p16 expression was elevated in hypoxia-treated cells and AMI group tissues. MiR-24-3p could sponge p16 in hypoxia-treated cells. Furthermore, the impact of applying miR-24-3p inhibitor on PsA and hypoxia-treated cells could be reversed by si-p16. PsA relieved hypoxia-triggered cell toxicity via miR-24-3p/p16 axis. These findings provided some fresh insights into the potential therapeutic effects of the application of PsA in AMI. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results