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Your search keyword '"Lychagin, Alexey V."' showing total 16 results
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16 results on '"Lychagin, Alexey V."'

5. Cardiovascular therapy in patients hospitalized for elective large joint arthroplasty: real-world practice review

Author

Okisheva, Elena A., primary, Mironova, Olga Iu., additional, Madoyan, Maria D., additional, Fidanyan, Svetlana E., additional, Semenova, Aida I., additional, Panferov, Alexandr S., additional, Strokov, Andrey V., additional, Tarabarko, Ivan N., additional, Garkavi, Andrey V., additional, Lychagin, Alexey V., additional, and Fomin, Victor V., additional

Published
2023
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8. Grading cartilage damage with diffuse reflectance spectroscopy: Optical markers and mechanical properties

Author

Rovnyagina, Nataliya R., primary, Budylin, Gleb S., additional, Dyakonov, Pavel V., additional, Efremov, Yuri M., additional, Lipina, Marina M., additional, Goncharuk, Yuliya R., additional, Murdalov, Emirkhan E., additional, Pogosyan, David A., additional, Davydov, Denis A., additional, Korneev, Alexander A., additional, Serejnikova, Natalia B., additional, Mikaelyan, Karen A., additional, Evlashin, Stanislav A., additional, Lazarev, Vladimir A., additional, Lychagin, Alexey V., additional, Timashev, Peter S., additional, and Shirshin, Evgeny A., additional

Published
2022
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9. Biodegradable iron-silicon implants produced by additive manufacturing

Author

Bondareva, Julia, primary, Dubinin, Oleg N., additional, Kuzminova, Yulia O., additional, Shpichka, Anastasia I., additional, Kosheleva, Nastasya V., additional, Lychagin, Alexey V., additional, Shibalova, Anastasia A., additional, Pozdnyakov, Artem A., additional, Akhatov, Iskander, additional, Timashev, Peter, additional, and Evlashin, Stanislav Alexandrovich, additional

Published
2022
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10. Grading cartilage damage with diffuse reflectance spectroscopy: Optical markers and mechanical properties.

Author

Rovnyagina, Nataliya R., Budylin, Gleb S., Dyakonov, Pavel V., Efremov, Yuri M., Lipina, Marina M., Goncharuk, Yuliya R., Murdalov, Emirkhan E., Pogosyan, David A., Davydov, Denis A., Korneev, Alexander A., Serejnikova, Natalia B., Mikaelyan, Karen A., Evlashin, Stanislav A., Lazarev, Vladimir A., Lychagin, Alexey V., Timashev, Peter S., and Shirshin, Evgeny A.

Abstract

Osteoarthritis (OA) is one of the most common joint diseases worldwide. Unfortunately, clinical methods lack the ability to detect OA in the early stages. Timely detection of the knee joint degradation at the level of tissue changes can prevent its progressive damage. Here, diffuse reflectance spectroscopy (DRS) in the NIR range was used to obtain optical markers of the cartilage damage grades and to assess its mechanical properties. It was observed that the water content obtained by DRS strongly correlates with the cartilage thickness (R =.82) and viscoelastic relaxation time (R =.7). Moreover, the spectral parameters, including water content (OH‐band), protein content (CH‐band), and scattering parameters allowed for discrimination between the cartilage damage grades (10−4 < P ≤ 10−3). The developed approach may become a valuable addition to arthroscopy, helping to identify lesions at the microscopic level in the early stages of OA and complement the surgical analysis. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Autologous bone marrow-derived mesenchymal stem cells provide complete regeneration in a rabbit model of the Achilles tendon bundle rupture

Author

Chailakhyan, Ruben K., primary, Kon, Elizaveta, additional, Shekhter, Anatoly B., additional, Ivannikov, Sergey V., additional, Telpukhov, Vladimir I., additional, Grosheva, Alla G., additional, Suslin, Dmitry S., additional, Vorobieva, Nataliya N., additional, Gerasimov, Yury V., additional, Churbanov, Semyon N., additional, Kotova, Svetlana, additional, Fayzullin, Alexey L., additional, Lychagin, Alexey V., additional, Lipina, Marina M., additional, and Timashev, Peter S., additional

Published
2021
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13. Lactoferrin as a regenerative agent: The old-new panacea?

Author

Antoshin, Artem A., primary, Shpichka, Anastasia I., additional, Huang, Guilin, additional, Chen, Kuo, additional, Lu, Pengwei, additional, Svistunov, Andrey A., additional, Lychagin, Alexey V., additional, Lipina, Marina M., additional, Sinelnikov, Mikhail Y., additional, Reshetov, Igor V., additional, and Timashev, Peter S., additional

Published
2021
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15. Evaluation of the potential complications of surgical wound drainage in primary total hip arthroplasty: a prospective controlled double-blind study.

Author

Lychagin, Alexey V, Rosenberg, Nahum, and Gritsyuk, Andrey A

Subjects
*C-reactive protein, *TOTAL hip replacement, *CLINICAL trials, *HEMOGLOBINS, *HEMATOCRIT, *POSTOPERATIVE care, *VISUAL analog scale, *HEALTH surveys, *RISK assessment, *T-test (Statistics), *SURGICAL site, *BLIND experiment, *QUESTIONNAIRES, *DESCRIPTIVE statistics, *BLOOD sedimentation, *MEDICAL drainage, *LONGITUDINAL method
Abstract

Background: The routine use of postoperative wound drainage following total hip arthroplasty (THA) to avoid the creation of excessive haematomas is controversial because of the potential risk of blood loss and wound infection. Methods: In a prospective double-blind controlled study, 2 groups of patients with hip joint osteoarthritis were operated with primary THA, 1 with surgical wound negative pressure drainage (Group 1 – 635 patients) and the other without (Group 2 – 527 patients). Postoperative blood haemoglobin and haematocrit levels, the necessity for blood transfusion, values of the potential infection markers (serum C-reactive protein values and erythrocyte sedimentation rate), postoperative pain level (according to the VAS scale) and functional outcome (according to Harris Hip Score [HHS] and SF-36 scores) at 12 months postoperatively were compared. Results: A significantly higher drop in blood haemoglobin and haematocrit values was observed in the Group 1 patients (mean drop of 2.2 gr/dl ± 0.25 vs. 1.6 gr/dl ± 0.35 and mean drop of 16% ± 4.0 vs. 11% ± 3.0, respectively, p < 0.01, paired t test). The need for blood transfusion was significantly higher in the Group 1 patients (4.9% vs. 3.9%, p < 0.05, t test). The severity of pain (VAS scale) on the first day after the operation was significantly lower in the Group 1 patients (p < 0.05, t test), but overall, in both groups it was of low intensity (VAS <3). A similar postoperative wound infection rate was observed in both groups (0.4%). HHS and SF-36 scores were similar in both groups. Conclusions: The drainage of surgical wounds following primary THA due to hip osteoarthritis has a low added value and might cause an increased requirement for blood transfusion. [ABSTRACT FROM AUTHOR]

Published
2021
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